Monte carlo simulation of an X-ray pixel beam microirradiation system.

abstract：:Nearly 2% of the male population of Estonia aged 20-39 years were sent to Chernobyl to assist in the cleanup activities after the reactor accident. A cohort of 4,833 cleanup workers was assembled based on multiple and independent sources of information. Information obtained from 3,704 responses to a detailed questionn...

journal_title：Radiation research

authors： Tekkel M,Rahu M,Veidebaum T,Hakulinen T,Auvinen A,Rytömaa T,Inskip PD,Boice JD Jr

更新日期：1997-05-01 00:00:00

abstract：:Understanding the cognitive and behavioral consequences of brain exposures to low-dose ionizing radiation has broad relevance for health risks from medical radiation diagnostic procedures, radiotherapy and environmental nuclear contamination as well as for Earth-orbit and space missions. Analyses of transcriptome prof...

journal_title：Radiation research

authors： Lowe XR,Bhattacharya S,Marchetti F,Wyrobek AJ

更新日期：2009-01-01 00:00:00

abstract：:Numerous experimental and clinical studies have been completed regarding the effects of carbogen and nicotinamide on tumor oxygenation and radiosensitivity. The current study incorporates three physiological measurement techniques to further define spatial variations in oxygen availability and development of hypoxia a...

journal_title：Radiation research

authors： Fenton BM,Lord EM,Paoni SF

更新日期：2000-01-01 00:00:00

abstract：:The lineal energy distribution and several other dosimetric parameters were measured for the neutrons emitted from a replica of the Hiroshima bomb to determine their usefulness in biological experiments designed to estimate the effectiveness of actual Hiroshima neutrons. The "Little-Boy" replica (LBR) was constructed ...

journal_title：Radiation research

authors： Straume T,McDonald JC,Pederson RA,Brenner DJ,Dobson RL

更新日期：1991-11-01 00:00:00

abstract：:Carcinogenesis is a multistep process, involving the irreversible conversion of a stem cell to a terminal-differentiation-resistant cell ("initiation"), followed by the clonal expansion of this cell ("promotion") and by the acquisition of other genetic alterations leading to malignancy ("progression"). The initiation ...

journal_title：Radiation research

authors： Trosko JE,Chang CC,Madhukar BV

更新日期：1990-09-01 00:00:00

abstract：:Tritium that is bound to organic molecules is of special risk for living systems, in particular when such molecules are components of the cell nucleus. Therefore, [3H]thymidine and [3H]arginine were studied for radiotoxicity in early mammalian embryo development. Starting with the two-cell stage, mouse embryos were in...

journal_title：Radiation research

authors： Müller WU,Streffer C,Molls M,Glück L

更新日期：1987-05-01 00:00:00

abstract：:Ion microscopy was used for subcellular quantitative imaging of the isotopes 10B and 11B in the same cell to evaluate boron delivery using a mixture of two neutron capture therapy drugs, p-boronophenylalanine-fructose (BPA-F) and sodium borocaptate (BSH). The application of 10B-labeled BPA-F and 11B-labeled BSH allowe...

journal_title：Radiation research

authors： Chandra S,Lorey II DR,Smith DR

更新日期：2002-06-01 00:00:00

abstract：:Metallothionein (MT), the synthesis of which can be induced by metalloelement administration, is a known radical scavenger. This study investigated the possible protective effect of MT against acute radiation injury. Manganese chloride (10 mg of manganese/kg) was administered intraperitoneally to male C3H/He mice 24 h...

journal_title：Radiation research

authors： Murata R,Nishimura Y,Hiraoka M,Abe M,Satoh M

更新日期：1995-09-01 00:00:00

abstract：:Studies have causally linked external thyroid radiation exposure in childhood with thyroid cancer. In 1995, investigators conducted relative risk analyses of pooled data from seven epidemiologic studies. Doses were mostly <10 Gy, although childhood cancer therapies can result in thyroid doses >50 Gy. We pooled data fr...

journal_title：Radiation research

authors： Veiga LH,Holmberg E,Anderson H,Pottern L,Sadetzki S,Adams MJ,Sakata R,Schneider AB,Inskip P,Bhatti P,Johansson R,Neta G,Shore R,de Vathaire F,Damber L,Kleinerman R,Hawkins MM,Tucker M,Lundell M,Lubin JH

更新日期：2016-05-01 00:00:00

abstract：:This commentary considers modulation as a factor of potential biological importance in assessment of risk of radiofrequency (RF) energy emitted by communications systems and other technologies. Modulation introduces a spread of frequencies into a carrier waveform, but in nearly all cases this spread is small compared ...

journal_title：Radiation research

authors： Foster KR,Repacholi MH

更新日期：2004-08-01 00:00:00

abstract：:The response of the testes of two strains of adult rats (Sprague-Dawley and Wistar) to graded single doses and split doses of 230 kVp X rays has been investigated. A marked difference was noted between the strains in the response of the clonogenic spermatogonia to irradiation, as measured histologically by the repopul...

journal_title：Radiation research

authors： Delic JI,Schlappack OK,Harwood JR,Stanley JA

更新日期：1987-10-01 00:00:00

abstract：:The current status of particle radiotherapy from a historical perspective is presented. This is done with a personal view and contains personal references and memories during the development of particle radiotherapy. The particles covered are fast neutrons, neutron capture therapy, protons, helium ions, pions and heav...

journal_title：Radiation research

authors： Raju MR

更新日期：1996-04-01 00:00:00

abstract：:Involvement of gap junctional intercellular communication (GJIC) in bystander responses of confluent human fibroblasts irradiated with a carbon-ion beam was investigated. It was found that the lower the radiation dose, the higher the yield of radiation-induced micronuclei per nuclear traversal, suggesting the existenc...

journal_title：Radiation research

authors： Shao C,Furusawa Y,Aoki M,Ando K

更新日期：2003-09-01 00:00:00

abstract：:The monohydroxylated fatty acid content of peripheral blood mononuclear cells from 23 cleanup workers and 16 unexposed individuals was studied in relation to their immune status after the Chernobyl accident. Men with absorbed doses below 0.32 Gy showed higher levels of free and esterified 12-hydroxyeicosatetraenoic ac...

journal_title：Radiation research

authors： Chumak A,Thevenon C,Gulaya N,Guichardant M,Margitich V,Bazyka D,Kovalenko A,Lagarde M,Prigent AF

更新日期：2001-11-01 00:00:00

abstract：:On future missions into deep space, astronauts will be required to work more autonomously than on previous missions, and thus their ability to perform executive functions could be critical to mission success. In this study, we determined the effect that ≤15 cGy of 600 MeV/n 56Fe particles has on attentional set-shifti...

journal_title：Radiation research

authors： Jewell JS,Duncan VD,Fesshaye A,Tondin A,Macadat E,Britten RA

更新日期：2018-12-01 00:00:00

abstract：:Sequential examinations were done on the pulmonary cytokinetics and pulmonary lesions in rats after inhalation exposure to (239)PuO(2) aerosols to investigate the pathogenesis of lung tumors. Total cell yields of lavaged bronchoalveolar cells as well as the estimated numbers of pulmonary alveolar macrophages were sign...

journal_title：Radiation research

authors： Oghiso Y,Yamada Y

更新日期：2000-09-01 00:00:00

abstract：:The widely distributed xanthine oxidoreductase (XOR) system has been shown to be modulated upon exposure of animals to ionizing radiation through the conversion of xanthine dehydrogenase (XDH) into xanthine oxidase (XO). In the present work, radiomodification of the XOR system by phenylmethylsulfonyl fluoride (PMSF) a...

journal_title：Radiation research

authors： Srivastava M,Kale RK

更新日期：2000-07-01 00:00:00

abstract：:The effect of heat exposure on the repair of radiation-induced DNA damage which inhibits the ability of nuclear DNA to undergo supercoiling changes was studied using the fluorescent halo assay in thermotolerant and nonthermotolerant (normal) cells. The assay utilizes an intercalating, fluorescent dye to unwind and rew...

journal_title：Radiation research

authors： Wynstra JH,Wright WD,Roti Roti JL

更新日期：1990-10-01 00:00:00

abstract：:We present measurements of low-energy (<18 eV) electron-stimulated desorption of anions from acetamide (CH(3)CONH(2)) and dimethyl disulfide [DMDS: (CH(3)S)(2)] films. Electron irradiation of physisorbed CH(3)CONH(2) produces H(-), CH(3)(-) and O(-) anions, whereas the H(-), CH(2)(-), CH(3)(-), S(-), SH(-) and SCH(3)(...

journal_title：Radiation research

authors： Abdoul-Carime H,Cecchini S,Sanche L

更新日期：2002-07-01 00:00:00

abstract：:Cellular nonprotein thiols (NPSH) consist of glutathione (GSH) and other low molecular weight species such as cysteine, cysteamine, and coenzyme A. GSH is usually less than the total cellular NPSH, and with thiol reactive agents, such as diethyl maleate (DEM), its rate of depletion is in part dependent upon the cellul...

journal_title：Radiation research

authors： Biaglow JE,Varnes ME,Clark EP,Epp ER

更新日期：1983-09-01 00:00:00

abstract：:Although skin is usually exposed during human exposures to ionizing radiation, there have been no thorough examinations of the transcriptional response of skin fibroblasts and keratinocytes to radiation. The transcriptional response of quiescent primary fibroblasts and keratinocytes exposed to from 10 cGy to 5 Gy and ...

journal_title：Radiation research

authors： Warters RL,Packard AT,Kramer GF,Gaffney DK,Moos PJ

更新日期：2009-07-01 00:00:00

abstract：:The German Thorotrast study comprises 2,326 patients and 1,890 controls. Forty-eight Thorotrast patients and 239 controls are still alive and are invited for a follow-up examination every 2 years. In the deceased patients, the following neoplastic diseases with excess rates were registered (Thorotrast/controls): liver...

journal_title：Radiation research

authors： van Kaick G,Dalheimer A,Hornik S,Kaul A,Liebermann D,Lührs H,Spiethoff A,Wegener K,Wesch H

更新日期：1999-12-01 00:00:00

abstract：:After total-body exposure to various doses of ionizing radiation, the ability of lymphocytes to interact specifically with high endothelial venules of rat cervical and mesenteric lymph nodes was analyzed in frozen sections. Following a radiation dose of 1.5 Gy, high endothelial venules remained intact and the binding ...

journal_title：Radiation research

authors： Hale ML,Briggs R,McCarthy KF

更新日期：1991-02-01 00:00:00

abstract：:Potentially lethal damage (PLD) repair has been defined as that property conferring the ability of cells to recover from DNA damage depending on the postirradiation environment. Using a novel cyclin dependent kinase 1 inhibitor RO-3306 to arrest cells in the G2 phase of the cell cycle, examined PLD repair in G2 in cul...

journal_title：Radiation research

authors： Maeda J,Bell JJ,Genet SC,Fujii Y,Genet MD,Brents CA,Genik PC,Kato TA

更新日期：2014-10-01 00:00:00

abstract：:Peroxidation of unconjugated polyunsaturated fatty acids such as linolenic acid proceeds through a free radical chain mechanism and is accompanied by the formation of conjugated dienes such as hydroperoxides. In an investigation of radiation-induced oxidation of aqueous linolenate, we have measured two indexes of pero...

journal_title：Radiation research

authors： Hindo J,Hauville C,Rémita S,Thérond P,Couturier M,Jore D,Gardès-Albert M

更新日期：2000-02-01 00:00:00

abstract：:The relationship of ionizing radiation to the age-related ophthalmological findings of the 1978-1980 ophthalmological examination of A-bomb survivors of Hiroshima and Nagasaki has been reanalyzed using DS86 eye organ dose estimates. The main purpose of this reevaluation was to determine whether age and radiation expos...

journal_title：Radiation research

authors： Otake M,Finch SC,Choshi K,Takaku I,Mishima H,Takase T

更新日期：1992-09-01 00:00:00

abstract：:An in vitro assay was used to assess cell killing and induction of neoplastic transformation in C3H 10T1/2 cells exposed to X rays and a range of monoenergetic neutrons administered at various dose rates. Curves for cell survival and induction of neoplastic transformation showed nonlinearity for cells exposed to acute...

journal_title：Radiation research

authors： Miller RC,Hall EJ

更新日期：1991-10-01 00:00:00

abstract：:We report here on a qualitative and quantitative comparison of four kinetic photon cell survival models. The commonly used linear-quadratic model extended by a dose protraction factor, the lethal potentially lethal model, the repair misrepair model and the recently reported Giant LOop Binary LEsion (GLOBLE) model are ...

journal_title：Radiation research

authors： Herr L,Friedrich T,Durante M,Scholz M

更新日期：2015-11-01 00:00:00

abstract：:Radiation-induced apoptosis in lymphocyte-derived cell lines is characterized by endonucleolytic cleavage of cellular DNA within hours after radiation exposure. We have studied this phenomenon qualitatively (DNA gel electrophoresis) and quantitatively (diphenylamine reagent assay) in murine EL4 T-lymphoma cells expose...

journal_title：Radiation research

authors： Palayoor ST,Macklis RM,Bump EA,Coleman CN

更新日期：1995-03-01 00:00:00

abstract：:Deep-space travel presents risks of exposure to ionizing radiation composed of a spectrum of low-fluence protons (1H) and high-charge and energy (HZE) iron nuclei (e.g., 56Fe). When exposed to galactic cosmic rays, each cell in the body may be traversed by 1H every 3-4 days and HZE nuclei every 3-4 months. The effects...

journal_title：Radiation research

authors： Sasi SP,Yan X,Zuriaga-Herrero M,Gee H,Lee J,Mehrzad R,Song J,Onufrak J,Morgan J,Enderling H,Walsh K,Kishore R,Goukassian DA

更新日期：2017-08-01 00:00:00