Relationship between sum of the four limbs' pulse pressure and brachial-ankle pulse wave velocity and atherosclerosis risk factors in Chinese adults.

Abstract:

:The aim of the present study was to analyze the relationship between the sum of the four limbs' pulse pressure (Sum-PP) and brachial-ankle pulse wave velocity (baPWV) and atherosclerosis risk factors and evaluate the feasibility of Sum-PP in diagnosing atherosclerosis systemically. For the purpose, a cross-sectional study was conducted on the basis of medical information of 20748 adults who had a health examination in our hospital. Both Sum-PP and baPWV exhibited significant variations among different human populations grouped by gender, smoking, drinking, and age. Interestingly, Sum-PP had similar varying tendency with baPWV in different populations. And further study in different populations showed that Sum-PP was significantly positively related to baPWV. We also investigated the relationship between Sum-PP, baPWV, and cardiovascular risk factors, respectively. We found that both Sum-PP and baPWV had significant positive correlation with atherosclerosis risk factors while both of them were negatively related to HDL-c. In addition, there was a significant close correlation between Sum-PP and baPWV in the whole population (r = 0.4616, P < 0.0001). Thus, Sum-PP is closely related to baPWV and is of important value for clinical diagnosis of atherosclerosis.

journal_name

Biomed Res Int

authors

Zheng Y,Li Z,Shu H,Liu M,Chen Z,Huang J

doi

10.1155/2015/434516

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

434516

eissn

2314-6133

issn

2314-6141

journal_volume

2015

pub_type

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