Protective Effects of Emodin-Induced Neutrophil Apoptosis via the Ca2+-Caspase 12 Pathway against SIRS in Rats with Severe Acute Pancreatitis.

abstract：:Coconut palm (Cocos nucifera) is an important commercial crop in many tropical countries, but its industry generates large amounts of residue. One way to address this problem is to use this residue, coconut husk, to produce second-generation (2G) ethanol. The aim of this review is to describe the methods that have bee...

journal_title：BioMed research international

authors： Bolivar-Telleria M,Turbay C,Favarato L,Carneiro T,de Biasi RS,Fernandes AAR,Santos AMC,Fernandes PMB

更新日期：2018-09-27 00:00:00

abstract：:Bone tissue is continuously remodeled through the concerted actions of bone cells, which include bone resorption by osteoclasts and bone formation by osteoblasts, whereas osteocytes act as mechanosensors and orchestrators of the bone remodeling process. This process is under the control of local (e.g., growth factors ...

journal_title：BioMed research international

authors： Florencio-Silva R,Sasso GR,Sasso-Cerri E,Simões MJ,Cerri PS

更新日期：2015-01-01 00:00:00

abstract：:Hosts' innate defense systems are upregulated by antimicrobial peptide elicitors (APEs). Our aim was to investigate the effects of hyperthermia, ultraviolet A rays (UVA), and ultraviolet C rays (UVC) as well as glucose and ascorbic acid (AA) on the regulation of human β-defensin 1 (DEFB1), cathelicidin (CAMP), and int...

journal_title：BioMed research international

authors： Cruz Díaz LA,Flores Miramontes MG,Chávez Hurtado P,Allen K,Gonzalez Ávila M,Prado Montes de Oca E

更新日期：2015-01-01 00:00:00

abstract：:The nonnucleoside reverse transcriptase inhibitors, used for the treatment of HIV infections, are reported to have low bioavailability pertaining to high first-pass metabolism, high protein binding, and enzymatic metabolism. They also show low permeability across blood brain barrier. The CNS is reported to be the most...

journal_title：BioMed research international

authors： Gupta S,Kesarla R,Chotai N,Misra A,Omri A

更新日期：2017-01-01 00:00:00

abstract：:Embryology of normal web space creation and the genetics of syndactyly in humans and experimental animals are well described in the literature. In this review, the author offers a 3-step pathway of pathogenesis for syndactyly. The first step is initiated either by the overactivation of the WNT canonical pathway or the...

journal_title：BioMed research international

authors： Al-Qattan MM

更新日期：2019-09-15 00:00:00

abstract：:This study aims to evaluate whether diets containing mixture of formic and propionic acid alone or supplemented with either capric acid or Bacillus Licheniformis can alleviate immune inflammatory response of piglets challenged with enterotoxigenic Escherichia coli (ETEC). A total of 30 weaning pigs were assigned to 5 ...

journal_title：BioMed research international

authors： Ren C,Zhou Q,Guan W,Lin X,Wang Y,Song H,Zhang Y

更新日期：2019-03-25 00:00:00

abstract：:Iron deficiency anemia has been a widespread disease. As an effective and stable iron supplement, the physiochemical properties of the polysaccharide iron complex have been widely studied. In this study, we characterized a novel polysaccharide-iron(III) complex extracted in an edible fungal species Auricularia auricul...

journal_title：BioMed research international

authors： Liu T,Liu T,Liu H,Fan H,Chen B,Wang D,Zhang Y,Sun F

更新日期：2019-06-11 00:00:00

abstract：:The achievement of successful biostimulation of active microbiomes for the cleanup of a polluted site is strictly dependent on the knowledge of the key microorganisms equipped with the relevant catabolic genes responsible for the degradation process. In this work, we present the characterization of the bacterial commu...

journal_title：BioMed research international

authors： Merlino G,Balloi A,Marzorati M,Mapelli F,Rizzi A,Lavazza D,de Ferra F,Carpani G,Daffonchio D

更新日期：2015-01-01 00:00:00

abstract：:Growing evidence indicates that immune-related biomarkers play an important role in tumor processes. This study investigates immune-related gene expression and its prognostic value in lung squamous cell carcinoma (LUSC). A cohort of 493 samples of patients with LUSC was collected and analyzed from data generated by th...

journal_title：BioMed research international

authors： Yan Y,Zhang M,Xu S,Xu S

更新日期：2020-06-27 00:00:00

abstract：Background:Glucagon-like peptide 1 (GLP-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic β-cell apoptosis. Currently, diabetes mellitus (DM) treatment based on GLP-1 work is being developed, fo...

journal_title：BioMed research international

authors： Kartinah NT,Fadilah F,Ibrahim EI,Suryati Y

更新日期：2019-11-11 00:00:00

abstract：Background:Acute myocardial infarction (AMI) is regarded as an urgent clinical entity, and identification of differentially expressed genes, lncRNAs, and altered pathways shall provide new insight into the molecular mechanisms behind AMI. Materials and Methods:Microarray data was collected to identify key genes and ln...

journal_title：BioMed research international

authors： Sheng X,Fan T,Jin X

更新日期：2020-10-06 00:00:00

abstract：:Sarcopenia is defined as a syndrome characterized by progressive and generalized loss of muscle mass and strength. The more rationale approach to delay the progression of sarcopenia is based on the combination of proper nutrition, possibly associated with the use of dietary supplements and a regular exercise program. ...

journal_title：BioMed research international

authors： Rondanelli M,Faliva M,Monteferrario F,Peroni G,Repaci E,Allieri F,Perna S

更新日期：2015-01-01 00:00:00

abstract：:Cancer is known to have unique metabolic features such as Warburg effect. Current cancer therapy has moved forward from cytotoxic treatment to personalized, targeted therapies, with some that could lead to specific metabolic changes, potentially monitored by imaging methods. In this paper we addressed the important as...

journal_title：BioMed research international

authors： Lin G,Chung YL

更新日期：2014-01-01 00:00:00

abstract：:In the past decade, much emphasis has been put on the transcriptional activation of HIV-1, which is proposed as a promised strategy for eradicating latent HIV-1 provirus. Two drugs, prostratin and hexamethylene bisacetamide (HMBA), have shown potent effects as inducers for releasing HIV-1 latency when used alone or in...

journal_title：BioMed research international

authors： Chen D,Wang H,Aweya JJ,Chen Y,Chen M,Wu X,Chen X,Lu J,Chen R,Liu M

更新日期：2016-01-01 00:00:00

abstract：:The normal physiological loads from muscles experienced by the spine are largely unknown due to a lack of data. The aim of this study is to investigate the effects of varying muscle directions on the outcomes predicted from finite element models of human lumbar spine. A nonlinear finite element model of L3-L5 was empl...

journal_title：BioMed research international

authors： Zhu R,Niu WX,Wang ZP,Pei XL,He B,Zeng ZL,Cheng LM

更新日期：2018-01-03 00:00:00

abstract：:There is minimal research of upper extremity joint dynamics during pediatric wheelchair mobility despite the large number of children using manual wheelchairs. Special concern arises with the pediatric population, particularly in regard to the longer duration of wheelchair use, joint integrity, participation and commu...

journal_title：BioMed research international

authors： Slavens BA,Schnorenberg AJ,Aurit CM,Graf A,Krzak JJ,Reiners K,Vogel LC,Harris GF

更新日期：2015-01-01 00:00:00

abstract：:Purpose. Analysis of early vascular and nerve complications of supracondylar humerus fractures in children. Material and Methods. 220 children hospitalized in the Pediatric Trauma-Orthopedic Department in the years 2004-2014. The group consisted of 143 males and 77 females. Results. Acute neurovascular complications o...

journal_title：BioMed research international

authors： Tomaszewski R,Wozowicz A,Wysocka-Wojakiewicz P

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the value of ecological momentary assessment in evaluating physical activity among children, adolescents, and adults. It also determines whether ecological momentary assessment fulfills the criteria of validity, reliability, objectivity, norms, and standardization appli...

journal_title：BioMed research international

authors： Marszalek J,Morgulec-Adamowicz N,Rutkowska I,Kosmol A

更新日期：2014-01-01 00:00:00

abstract：:Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb, i.e., the aetiological agent); the WHO has established this disease as high priority due to its ensuing mortality. Mtb uses a range of mechanisms for preventing its elimination by an infected host; new, viable alternatives for blocking th...

journal_title：BioMed research international

authors： Sánchez-Barinas CD,Ocampo M,Tabares L,Bermúdez M,Patarroyo MA,Patarroyo ME

更新日期：2019-04-14 00:00:00

abstract：:Antibiotics are among the most counterfeited anti-infectious medicines in developing countries. Amoxicillin is one of the commonly prescribed, affordable, and easily accessible antibiotic in Kenya. It is a broad-spectrum antibiotic hence commonly used in chemotherapy. This study sought to determine the quality and ide...

journal_title：BioMed research international

authors： Koech LC,Irungu BN,Ng'ang'a MM,Ondicho JM,Keter LK

更新日期：2020-06-12 00:00:00

abstract：Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

journal_title：BioMed research international

authors： Zhang L,Song X,Li X,Wu C,Jiang J

更新日期：2018-11-14 00:00:00

abstract：:Understanding the mechanism behind the structure of the internal cellular clock can lead to advances in the knowledge of origins of pairs of monozygotic twins and higher order multiples as well as other biological phenomena. To gain insight into this mechanism, we analyze possible cell labeling schemes that model an o...

journal_title：BioMed research international

authors： Jim C,Berkovich S

更新日期：2015-01-01 00:00:00

abstract：:The p53-related p63 gene encodes multiple protein isoforms, which are involved in a variety of biological activities. p63 protein stability is mainly regulated by the ubiquitin-dependent proteasomal degradation pathway. Several ubiquitin E3 ligases have been identified and some protein kinases as well as other kinds o...

journal_title：BioMed research international

authors： Li C,Xiao ZX

更新日期：2014-01-01 00:00:00

abstract：:Dental modeling resins have been developed for use in areas where highly precise resin structures are needed. The manufacturers claim that these polymethyl methacrylate/methyl methacrylate (PMMA/MMA) resins show little or no shrinkage after polymerization. This study examined the polymerization shrinkage of five denta...

journal_title：BioMed research international

authors： Kwon TY,Ha JY,Chun JN,Son JS,Kim KH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the microshear bond strength (μSBS) of self-adhesive resin (SA) cement on leucite-reinforced glass-ceramic using silane or universal adhesive. MATERIALS AND METHODS:Ceramic blocks were etched with 9.5% hydrofluoric acid and divided into three groups (n = 16): (1) negative control (NC) without tre...

journal_title：BioMed research international

authors： Lee Y,Kim JH,Woo JS,Yi YA,Hwang JY,Seo DG

更新日期：2015-01-01 00:00:00

abstract：:Toxoplasma gondii (T. gondii) can be transmitted by blood transfusion. We determined the prevalence of T. gondii infection in healthy blood donors in Hermosillo city, Mexico, and the association of infection with T. gondii with the sociodemographic, clinical, and behavioral characteristics of blood donors. Four hundre...

journal_title：BioMed research international

authors： Alvarado-Esquivel C,Rascón-Careaga A,Hernández-Tinoco J,Corella-Madueño MA,Sánchez-Anguiano LF,Aldana-Madrid ML,Velasquez-Vega E,Quizán-Plata T,Navarro-Henze JL,Badell-Luzardo JA,Gastélum-Cano JM,Liesenfeld O

更新日期：2016-01-01 00:00:00

abstract：:Natural plant extracts contain a variety of phenolic compounds which are assigned various biological activities. Our work aims to make a quantitative and qualitative characterization of the Zest (ZL) and the Flesh (FL) of lemon (Citrus limon), to valorize the pharmacological uses of lemon, by evaluating in vitro activ...

journal_title：BioMed research international

authors： Makni M,Jemai R,Kriaa W,Chtourou Y,Fetoui H

更新日期：2018-01-15 00:00:00

abstract：:L5 spinal nerve ligation (SNL) in rats is one of the most popular models for studying neuropathic pain because of its high reproducibility. During the surgery, a part of the L5 paraspinal muscle is usually removed, which produces extra trauma and may potentially affect the physiological processes involved in neuropath...

journal_title：BioMed research international

authors： Huang YG,Zhang Q,Wu H,Zhang CQ

更新日期：2016-01-01 00:00:00

abstract：:Schistosomiasis is the most prevalent tropical disease in the world after malaria. According to the World Health Organization, the disease afflicts more than 240 million people in about 80 countries. Recently, an epidemiological surveillance study performed between 1997 and 2010 by the European Network for Tropical Me...

journal_title：BioMed research international

authors： Brindicci G,Santoro CR,De Laurentiis V,Capolongo C,Solarino ME,Papagni R,Ciracì E,Gatti P,Loconsole D,Monno R,Monno L,Miragliotta G,Angarano G

更新日期：2017-01-01 00:00:00

abstract：:Recent reports of retinal stem cells being present in several locations of the adult eye have sparked great hopes that they may be used to treat the millions of people worldwide who suffer from blindness as a result of retinal disease or injury. A population of proliferative cells derived from the ciliary body epithel...

journal_title：BioMed research international

authors： Frøen R,Johnsen EO,Nicolaissen B,Facskó A,Petrovski G,Moe MC

更新日期：2013-01-01 00:00:00