Foreword: all things considered about probiotics, prebiotics and ıntestinal microbiota in children - from bench to bedside.

Abstract:

:There are numerorus published and ongoing experimental/clinical studies about probiotics and prebiotics, intestinal microbiota and nutrition. Three years ago, at the first International Symposium of Probiotics Prebiotics in Paediatrics in Istanbul (2012) we highlighted the 'paediatric perspective' on these issues and brought together more than 40 global key opinion leaders and 400 attendants to have a chance to extensively discuss the past, present and the future. In 2014, the second state of art congress, held in Antalya, aimed to discuss the gut microbiota and microbiotics and their impact through lifespan. Selected papers of this conference are presented in this special issue 'prebiotics and probiotics in paediatrics' of Beneficial Microbes. A summary of the conference results is provided below.

journal_name

Benef Microbes

journal_title

Beneficial microbes

authors

Ozen M,Dinleyici EC

doi

10.3920/BM2014.x002

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

153-7

issue

2

eissn

1876-2883

issn

1876-2891

pii

7667T56700882327

journal_volume

6

pub_type

  • The use of konjac glucomannan hydrolysates to recover healthy microbiota in infected vaginas treated with an antifungal agent.

    abstract::The aim of this study was to evaluate how konjac glucomannan hydrolysates (GMH) could support the healthy re-colonisation of vaginal microflora post infections. A total of 26 female patients (12 controls and 14 treatments) aged 18 to 25 suffering from vaginal infection were recruited for this study. Patients were assi...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,随机对照试验

    doi:10.3920/BM2011.0021

    authors: Tester R,Al-Ghazzewi F,Shen N,Chen Z,Chen F,Yang J,Zhang D,Tang M

    更新日期:2012-03-01 00:00:00

  • Genes involved in protein metabolism of the probiotic lactic acid bacterium Lactobacillus delbrueckii UFV H2b20.

    abstract::A basic requirement for the prediction of the potential use of lactic acid bacteria (LAB) in the dairy industry is the identification of specific genes involved in flavour-forming pathways. The probiotic Lactobacillus delbrueckii UFV H2b20 was submitted to a genetic characterisation and phylogenetic analysis of genes ...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2011.0025

    authors: Do Carmo AP,da Silva DF,De Oliveira MN,Borges AC,De Carvalho AF,De Moraes CA

    更新日期:2011-09-01 00:00:00

  • Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 assimilate cholesterol and modulate ABCA1, CD36, NPC1L1 and SCARB1 in vitro.

    abstract::There is growing interest in the use of probiotic lactic acid bacteria (LAB) for prevention of hypercholesterolaemia. This study assessed the cholesterol lowering ability of Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 in growth media. Both LAB yielded >98% (39.2 μg/ml) cholesterol lowering in growt...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2016.0048

    authors: Lim FT,Lim SM,Ramasamy K

    更新日期:2017-02-07 00:00:00

  • Enterococcus mundtii ST4SA and Lactobacillus plantarum 423 excludes Listeria monocytogenes from the GIT, as shown by bioluminescent studies in mice.

    abstract::Listeria monocytogenes is an opportunistic food-borne pathogen and is life-threatening to individuals with a weakened immune system. The aim of this study was to determine if Lactobacillus plantarum 423 and Enterococcus mundtii ST4SA could prevent colonisation of L. monocytogenes in the gastro-intestinal tract (GIT). ...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2015.0082

    authors: van Zyl WF,Deane SM,Dicks LM

    更新日期:2016-01-01 00:00:00

  • Influence of Lactobacillus brevis 15 and Lactobacillus plantarum 13 on blood glucose and body weight in rats after high-fructose diet.

    abstract::In recent years, many authors have investigated the possible antidiabetic effect of lactic acid bacteria. Lactobacillus species constitute a major part of the lactic acid bacteria group and have been found to exhibit beneficial effects on the development of diabetes and its complications. In the current study, we inve...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2014.0012

    authors: Yakovlieva M,Tacheva T,Mihaylova S,Tropcheva R,Trifonova K,Toleкova A,Danova S,Vlaykova T

    更新日期:2015-01-01 00:00:00

  • Identification and characterisation of lactobacilli isolated from Kimere, a spontaneously fermented pearl millet dough from Mbeere, Kenya (East Africa).

    abstract::The objective of the study was to isolate potential probiotic lactobacilli from Kimere, a pearl millet dough prepared in the Mbeere community of Kenya, East Africa, by fermentation for 18-24 hours. Kimere samples, collected from 11 different homesteads in Mbeere, showed average pH values of 3.63±0.29. Counts of presum...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2010.0019

    authors: Njeru PN,Rösch N,Ghadimi D,Geis A,Bockelmann W,de Vrese M,Schrezenmeir J,Heller KJ

    更新日期:2010-09-01 00:00:00

  • Bifidobacteria and its rice fermented products on diet induced obese mice: analysis of physical status, serum profile and gene expressions.

    abstract::Obesity is highly correlated with the dysbiosis of intestinal microbiota, and bifidobacteria are one of the soft targets of this metabolic syndrome. The aim of this study is to evaluate the efficacy of Bifidobacterium sp. MKK4 and rice-based fermented foods on physical, haematological, gut microbiota and lypogenic-lyp...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2017.0056

    authors: Ray M,Hor PK,Ojha D,Soren JP,Singh SN,Mondal KC

    更新日期:2018-04-25 00:00:00

  • Phytate-degrading Pediococcus pentosaceus CFR R123 for application in functional foods.

    abstract::The present work looks at the role of phytate-degrading Pediococcus pentosaceus CFR R123 application in functional foods to evaluate the fate of phytate and calcium solubility during fermentation. Under standard conditions, CFR R123 grown in modified MRS containing sodium phytate CFR R123 showed 43% degradation of sod...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2010.0031

    authors: Raghavendra P,Ushakumari SR,Halami PM

    更新日期:2011-03-01 00:00:00

  • Is it who you are or what you do that is important in the human gut?

    abstract::The current leading view is that functionality and not phylotype is the most important determinant for the services provided by the gut microbiota. Here we present an alternative opinion, advocating the importance of phylotype in addition to function. We believe the literature is misled by technical artifacts in defin...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2013.0016

    authors: Avershina E,Rudi K

    更新日期:2013-09-01 00:00:00

  • Lactobacillus paracasei K5 displays adhesion, anti-proliferative activity and apoptotic effects in human colon cancer cells.

    abstract::Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain, isolated recently from feta-type cheese. Its probiotic potential has been demonstrated in a series of established in vitro tests. Moreover, incorporation of L. paracasei K5 as starter culture offered organoleptic and technological advantages to novel f...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2017.0183

    authors: Chondrou P,Karapetsas A,Kiousi DE,Tsela D,Tiptiri-Kourpeti A,Anestopoulos I,Kotsianidis I,Bezirtzoglou E,Pappa A,Galanis A

    更新日期:2018-12-07 00:00:00

  • Correlations between microbiota and metabolites after faecal microbiota transfer in irritable bowel syndrome.

    abstract::Faecal microbiota transfer (FMT) consists of the infusion of donor faecal material into the intestine of a patient with the aim to restore a disturbed gut microbiota. In this study, it was investigated whether FMT has an effect on faecal microbial composition, its functional capacity, faecal metabolite profiles and th...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2020.0010

    authors: Holster S,Repsilber D,Geng D,Hyötyläinen T,Salonen A,Lindqvist CM,Rajan SK,de Vos WM,Brummer RJ,König J

    更新日期:2020-12-22 00:00:00

  • The effect of probiotic Lactobacillus casei Shirota on knee osteoarthritis: a randomised double-blind, placebo-controlled clinical trial.

    abstract::Knee osteoarthritis (OA) treatment is challenging due to inefficacy and adverse effects of current medications. Probiotic treatment has been shown to promote bone metabolism, reduce pain and inflammatory responses of age-related musculoskeletal disorders, including OA. We aimed to investigate the effect of probiotic L...

    journal_title:Beneficial microbes

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3920/BM2016.0207

    authors: Lei M,Guo C,Wang D,Zhang C,Hua L

    更新日期:2017-10-13 00:00:00

  • Modulatory effect of three probiotic strains on infants' gut microbial composition and immunological parameters on a placebo-controlled, double-blind, randomised study.

    abstract::The gut microbiota plays a crucial role in gastrointestinal health. Current use of probiotics is aimed at modulating the bacterial gut composition to alleviate specific diseases. The safety and tolerance of three probiotic strains (Bifidobacterium longum subsp. infantis R0033, Lactobacillus helveticus R0052 and Bifido...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,随机对照试验

    doi:10.3920/BM2017.0132

    authors: De Andrés J,Manzano S,García C,Rodríguez JM,Espinosa-Martos I,Jiménez E

    更新日期:2018-06-15 00:00:00

  • Human milk mycobiota composition: relationship with gestational age, delivery mode, and birth weight.

    abstract::Intestinal and human milk microbiota studies during infancy have shown variations according to geographical location, delivery mode, gestational age, and mother-related factors during pregnancy. In this study, we performed metagenomic mycobiota analyses of 44 transient and mature human milk among five different groups...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2019.0158

    authors: Dinleyici M,Pérez-Brocal V,Arslanoglu S,Aydemir O,Ozumut SS,Tekin N,Vandenplas Y,Moya A,Dinleyici EC

    更新日期:2020-03-27 00:00:00

  • Milk fermented by Lactobacillus species from Brazilian artisanal cheese protect germ-free-mice against Salmonella Typhimurium infection.

    abstract::Ingestion of milks fermented by Lactobacillus strains showing probiotic properties is an important tool to maintain gastrointestinal health. In this study, Lactobacillus rhamnosus D1 and Lactobacillus plantarum B7, isolated from Brazilian artisanal cheese, were used as starters for the functional fermented milks to as...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2016.0163

    authors: Acurcio LB,Sandes SHC,Bastos RW,Sant'anna FM,Pedroso SHSP,Reis DC,Nunes ÁC,Cassali GD,Souza MR,Nicoli JR

    更新日期:2017-08-24 00:00:00

  • Resistant starch, large bowel fermentation and a broader perspective of prebiotics and probiotics.

    abstract::The metabolic end products of the large bowel microbiota contribute significantly to human health. After weaning to solid foods, some of the most important of these are the short chain fatty acids (SCFA) produced by the fermentation of undigested dietary components and endogenous secretions. The main SCFA are acetate,...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,评审

    doi:10.3920/BM2010.0041

    authors: Bird AR,Conlon MA,Christophersen CT,Topping DL

    更新日期:2010-11-01 00:00:00

  • The effects of the Lactobacillus casei strain on obesity in children: a pilot study.

    abstract::There are few data regarding the role of probiotics as a dietary intervention in the management of obesity in children. An open prospective examination was conducted to clarify the effects of Lactobacillus casei strain Shirota (LcS)-containing beverages in obese children. We compared the intestinal microbiota and orga...

    journal_title:Beneficial microbes

    pub_type: 临床试验,杂志文章

    doi:10.3920/BM2016.0170

    authors: Nagata S,Chiba Y,Wang C,Yamashiro Y

    更新日期:2017-08-24 00:00:00

  • Prebiotics to manage the microbial control of energy homeostasis.

    abstract::The prevalence of obesity is continuously growing and has reached epidemic proportions. It is clear that current methods to combat obesity are not effective enough to reduce the problem. Therefore, further investigation is needed to develop new strategies. Recent research pointed out a potential role of the microbial ...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,评审

    doi:10.3920/BM2011.0020

    authors: Grootaert C,Marzorati M,Van den Abbeele P,Van de Wiele T,Possemiers S

    更新日期:2011-12-01 00:00:00

  • Mechanisms and immunomodulatory properties of pre- and probiotics.

    abstract::The human body is exposed to many xenobiotic, potentially harmful compounds. The intestinal immune system is crucial in protecting the human body from these substances. Moreover, many microorganisms, residing in the gastrointestinal tract, play an important role in modulating immune responses. Pre- and probiotics may ...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,评审

    doi:10.3920/BM2018.0066

    authors: Peters VBM,van de Steeg E,van Bilsen J,Meijerink M

    更新日期:2019-04-19 00:00:00

  • Alteration of the intestinal microbiota as a cause of and a potential therapeutic option in irritable bowel syndrome.

    abstract::The intestinal microbiota forms a complex ecosystem that is in close contact with its host and has an important impact on health. An increasing number of disorders are associated with disturbances in this ecosystem. Also patients suffering from irritable bowel syndrome (IBS) show an altered composition of their gut mi...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,评审

    doi:10.3920/BM2013.0033

    authors: König J,Brummer RJ

    更新日期:2014-09-01 00:00:00

  • Lactobacillus acidophilus and Clostridium butyricum ameliorate colitis in murine by strengthening the gut barrier function and decreasing inflammatory factors.

    abstract::Ulcerative colitis is a type of chronic inflammation present in the intestines for which the aetiology is not yet clear. The current therapies for ulcerative colitis cannot be considered to be long-term management strategies due to their significant side effects. Therefore, it is essential to identify an alternative t...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2017.0035

    authors: Wang Y,Gu Y,Fang K,Mao K,Dou J,Fan H,Zhou C,Wang H

    更新日期:2018-09-18 00:00:00

  • Immune modulatory capacity of probiotic lactic acid bacteria and applications in vaccine development.

    abstract::Vaccination is one of the most important prevention tools providing protection against infectious diseases especially in children below the age of five. According to estimates, more than 5 million lives are saved annually by the implementation of six standard vaccines, including diphtheria, hepatitis B, Haemophilus in...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,评审

    doi:10.3920/BM2019.0121

    authors: Mojgani N,Shahali Y,Dadar M

    更新日期:2020-05-11 00:00:00

  • Bifidobacterium breve prevents necrotising enterocolitis by suppressing inflammatory responses in a preterm rat model.

    abstract::Necrotising enterocolitis (NEC) is associated with inflammatory responses and barrier dysfunction in the gut. In this study, we investigated the effect of Bifidobacterium breve M-16V on factors related to NEC development using an experimental rat model. Caesarean-sectioned rats were given formula milk with or without ...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2015.0035

    authors: Satoh T,Izumi H,Iwabuchi N,Odamaki T,Namba K,Abe F,Xiao JZ

    更新日期:2016-02-01 00:00:00

  • Cross-feeding between Bifidobacterium infantis and Anaerostipes caccae on lactose and human milk oligosaccharides.

    abstract::The establishment of the gut microbiota immediately after birth is a dynamic process that may impact lifelong health. At this important developmental stage in early life, human milk oligosaccharides (HMOs) serve as specific substrates to shape the gut microbiota of the nursling. The well-orchestrated transition is imp...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2020.0005

    authors: Chia LW,Mank M,Blijenberg B,Bongers RS,van Limpt K,Wopereis H,Tims S,Stahl B,Belzer C,Knol J

    更新日期:2020-11-16 00:00:00

  • Intestinal microbiota and oral administration of Enterococcus faecium associated with the growth performance of new-born piglets.

    abstract::The oral administration of Enterococcus faecium EF1 to new-born suckling and weaning piglets along with their growth performances and intestinal microbiota was investigated in this study. Twenty-four new-born piglets were initially divided into 2 groups. The probiotics group received 2 ml of 10% sterilised skimmed mil...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,随机对照试验

    doi:10.3920/BM2015.0099

    authors: Wang YB,Du W,Fu AK,Zhang XP,Huang Y,Lee KH,Yu K,Li WF,Li YL

    更新日期:2016-09-01 00:00:00

  • Bacteriocins of Gram-positive bacteria having activity spectra extending beyond closely-related species.

    abstract::Bacteriocins are bacterially-produced antimicrobial peptides that have killing activity principally against other relatively closely-related bacteria. Some bacteriocins of the lactic acid bacteria (LAB) have for many years been extensively applied in food biopreservation. However, especially during the last decade, a ...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,评审

    doi:10.3920/BM2018.0126

    authors: Todorov SD,de Melo Franco BDG,Tagg JR

    更新日期:2019-04-19 00:00:00

  • Dysbiosis in early sepsis can be modulated by a multispecies probiotic: a randomised controlled pilot trial.

    abstract::The gut is hypothesised to play an important role in the development and progression of sepsis. It is however unknown whether the gut microbiome and the gut barrier function is already altered early in sepsis development and whether it is possible to modulate the microbiome in early sepsis. Therefore, a randomised, do...

    journal_title:Beneficial microbes

    pub_type: 杂志文章,随机对照试验

    doi:10.3920/BM2018.0067

    authors: Stadlbauer V,Horvath A,Komarova I,Schmerboeck B,Feldbacher N,Klymiuk I,Durdevic M,Rainer F,Blesl A,Stiegler P,Leber B

    更新日期:2019-04-19 00:00:00

  • Anti-inflammatory properties of probiotic bacteria on Salmonella-induced IL-8 synthesis in enterocyte-like Caco-2 cells.

    abstract::Invasion of the gut by pathogenic Salmonella leads to production of IL-8 that initiates inflammatory reactions to combat the bacterium. However, its persistent production causes tissue damage and interventions that suppress IL-8 production prevent tissue damage. We hypothesised that probiotics could mediate their bene...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2009.0021

    authors: Malago JJ,Tooten PC,Koninkx JF

    更新日期:2010-06-01 00:00:00

  • Living cells of probiotic Bifidobacterium bifidum YIT 10347 detected on gastric mucosa in humans.

    abstract::The probiotic strain Bifidobacterium bifidum YIT 10347 has been demonstrated to inhibit Helicobacter pylori activity, prevent injury to the gastric mucosa, and improve general gastric malaise symptoms in H. pylori positive patients. This study aimed to investigate the adhering activity and localisation of B. bifidum Y...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2015.0138

    authors: Shibahara-Sone H,Gomi A,Iino T,Kano M,Nonaka C,Watanabe O,Miyazaki K,Ohkusa T

    更新日期:2016-06-01 00:00:00

  • On the importance of intraindividual variation in nutritional research.

    abstract::Nutritional intervention studies, like those with pre- and probiotics, are often hampered by low effect sizes, reducing the power to demonstrate potential efficacy. Here, we perform computer simulations of a hypothetical clinical trial using such an intervention in order to elucidate determining factors that can be in...

    journal_title:Beneficial microbes

    pub_type: 杂志文章

    doi:10.3920/BM2020.0044

    authors: Larsen OFA,Claassen E,Brummer RJ

    更新日期:2020-10-12 00:00:00