Cognitive performance during the first year of treatment in first-episode schizophrenia: a case-control study.

abstract：BACKGROUND:The coronavirus [coronavirus disease 2019 (COVID-19)] pandemic has introduced extraordinary life changes and stress, particularly in adolescents and young adults. Initial reports suggest that depression and anxiety are elevated during COVID-19, but no prior study has explored changes at the within-person lev...

journal_title：Psychological medicine

authors： Hawes MT,Szenczy AK,Klein DN,Hajcak G,Nelson BD

更新日期：2021-01-13 00:00:00

abstract：:A standardized pegboard task was used to investigate changes in manipulative skill as a function of age in 119 right-handed subjects. The typical pattern of cognitive impairment in old age indicates a relative preservation of functions which depend on the integrity of the left hemisphere. In accord with these observat...

journal_title：Psychological medicine

authors： Weller MP,Latimer-Sayer DT

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Neurocognitive functioning may be impaired in the luteal phase of the menstrual cycle due to associated changes in hypothalamic-pituitary adrenal (HPA) axis function. This study examines the relationship between changes in neurocognition and HPA axis function in different phases of the menstrual cycle. METH...

journal_title：Psychological medicine

authors： Symonds CS,Gallagher P,Thompson JM,Young AH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Depressive symptoms above screening thresholds have been shown to predict functional decline in older adults. Less is known about the impact of subthreshold depression, and whether more symptoms confer significantly greater risk compared to fewer symptoms. METHOD:Using data from the Duke Established Populat...

journal_title：Psychological medicine

authors： Hybels CF,Pieper CF,Blazer DG

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The World Mental Health Survey Initiative (WMHSI) has advanced our understanding of mental disorders by providing data suitable for analysis across many countries. However, these data have not yet been fully explored from a cross-national lifespan perspective. In particular, there is a shortage of research o...

journal_title：Psychological medicine

authors： McDowell RD,Ryan A,Bunting BP,O'Neill SM,Alonso J,Bruffaerts R,de Graaf R,Florescu S,Vilagut G,de Almeida JM,de Girolamo G,Haro JM,Hinkov H,Kovess-Masfety V,Matschinger H,Tomov T

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:We developed a comprehensive, 20-hour training programme for primary-care physicians, that sought to improve their ability to detect, diagnose and manage depression. We evaluated the effects of physician training on patient outcomes, using a pre-post design. METHODS:In the pre-training phase of the study, w...

journal_title：Psychological medicine

authors： Tiemens BG,Ormel J,Jenner JA,van der Meer K,Van Os TW,van den Brink RH,Smit A,van den Brink W

更新日期：1999-07-01 00:00:00

abstract：:A cohort of 181 users of community psychiatric services in Camberwell with at least one year's history of contact was traced for two years following a census day. Four of the eight patients who had been given a primary diagnosis of an organic condition died during this period. For the others the population-standardize...

journal_title：Psychological medicine

authors： Sturt E

更新日期：1983-05-01 00:00:00

abstract：:There have been numerous exhortations for more 'translational research'. A selective review of historical examples of research leading to health benefits is used to consider the various forms of successful interplay between basic science and clinical applications. This is followed by a consideration of key neuroscienc...

journal_title：Psychological medicine

authors： Rutter M,Plomin R

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Excessive worry is required by DSM-IV, but not ICD-10, for a diagnosis of generalized anxiety disorder (GAD). No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD. METHOD:Data were analyzed from the US Nationa...

journal_title：Psychological medicine

authors： Ruscio AM,Lane M,Roy-Byrne P,Stang PE,Stein DJ,Wittchen HU,Kessler RC

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The neurodevelopmental model of psychosis was established over 30 years ago; however, the developmental influence on psychotic symptom expression - how age affects clinical presentation in first-episode psychosis - has not been thoroughly investigated. METHODS:Using generalized additive modeling, which allo...

journal_title：Psychological medicine

authors： Bridgwater M,Bachman P,Tervo-Clemmens B,Haas G,Hayes R,Luna B,Salisbury DF,Jalbrzikowski M

更新日期：2020-10-06 00:00:00

abstract：BACKGROUND:Schizophrenia is associated with perceptual organization deficits and abnormal neuronal connectivity has been described in early visual areas. The purpose of this study was to investigate the functional integrity of lateral connections in early visual areas of patients with schizophrenia and type I bipolar d...

journal_title：Psychological medicine

authors： Kéri S,Kelemen O,Benedek G,Janka Z

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:It is clearly established that emotional events tend to be remembered particularly vividly. The neurobiological substrates of this phenomenon are poorly understood. Recently, the noradrenergic system has been implicated in that beta blockade has been shown to reduce significantly the delayed recall of emotio...

journal_title：Psychological medicine

authors： O'Carroll RE,Drysdale E,Cahill L,Shajahan P,Ebmeier KP

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Although numerous studies have examined the latent structure of major depression, less attention has focused on mania. This paper presents the first investigation outside the USA to evaluate the psychometric properties of the DSM-IV criterion B mania symptoms using item response theory (IRT). METHOD:Data we...

journal_title：Psychological medicine

authors： Carragher N,Weinstock LM,Strong D

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Dysregulation of the striatum and altered corticostriatal connectivity have been associated with psychotic disorders. Social anhedonia has been identified as a predictor for the development of schizophrenia spectrum disorders. The aim of the present study was to examine corticostriatal functional connectivit...

journal_title：Psychological medicine

authors： Wang Y,Liu WH,Li Z,Wei XH,Jiang XQ,Geng FL,Zou LQ,Lui SS,Cheung EF,Pantelis C,Chan RC

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Several psychological and neurobiological models imply that patients with schizophrenia (SCZ) are more inclined to utilize emotional cues as response determinants to the detriment of more task-appropriate cognitive or contextual cues. However, there is a lack of behavioural data from human clinical studies t...

journal_title：Psychological medicine

authors： Patrick RE,Christensen BK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:A long-standing issue in the health anxiety literature is the extent to which health anxiety is a dimensional or a categorical construct. This study explores this question directly using taxometric procedures. METHOD:Seven hundred and eleven working adults completed an index of health anxiety [the Whiteley ...

journal_title：Psychological medicine

authors： Ferguson E

更新日期：2009-02-01 00:00:00

abstract：:Inhibition of central dopamine functions appears to be a common basic property of antipsychotic drugs. The mesolimbic and nigrostriatal portions of the dopaminergic system are probably the main targets of these drugs for the mental and the extrapyramidal actions respectively. Dopaminergic hyperfunction, induced by amp...

journal_title：Psychological medicine

authors： Carlsson A

更新日期：1977-11-01 00:00:00

abstract：:A detailed analysis of the results of a multi-centre clinical trial shows that, while the relapse rate following recovery from an operationally defined depressive illness was smaller among patients subsequently treated with either amitryptiline or lithium than with a placebo, there was no clinically significant differ...

journal_title：Psychological medicine

authors： Glen AI,Johnson AL,Shepherd M

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Factor analysis has been employed to identify latent variables that are unifying constructs and that parsimoniously describe correlations among a related group of variables. Confirmatory factor analysis is used to test hypothesized factor structures for a set of variables; it can also, as in this paper be us...

journal_title：Psychological medicine

authors： Jacob KS,Everitt BS,Patel V,Weich S,Araya R,Lewis GH

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Depressive disorders are known to often be chronic and recurrent both in the general population and in psychiatric settings. However, despite its importance for public health and services, the outcome of depression in primary care is not well known. METHOD:In The Vantaa Primary Care Depression Study (PC-VDS...

journal_title：Psychological medicine

authors： Vuorilehto MS,Melartin TK,Isometsä ET

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:This study seeks to clarify the contribution of temporally stable and occasion-specific genetic and environmental influences on risk for major depression (MD). METHOD:Our sample was 2153 members of female-female twin pairs from the Virginia Twin Registry. We examined four personal interview waves conducted ...

journal_title：Psychological medicine

authors： Kendler KS,Gardner CO

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Anxiety disorders are very common and increase risk for suicide attempts. Little is known about predictors of increased risk specifically among individuals with anxiety disorders. The purpose of this study was to investigate whether specific anxiety disorders and other co-morbid psychiatric disorders, physic...

journal_title：Psychological medicine

authors： Uebelacker LA,Weisberg R,Millman M,Yen S,Keller M

更新日期：2013-07-01 00:00:00

abstract：:The SIDAM--a new instrument for the symptomatic diagnosis and measurement of dementia according to DSM-III-R and ICD-10--is described. It comprises a brief structured clinical interview, a range of cognitive tests (e.g. including the Mini-Mental State (Folstein et al. 1975)) which constitute a short neuropsychological...

journal_title：Psychological medicine

authors： Zaudig M,Mittelhammer J,Hiller W,Pauls A,Thora C,Morinigo A,Mombour W

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:The common mental disorders (CMDs) of anxiety and depression are the most common form of poor mental health in the general population. Evidence from the small number of previous cohort studies on the role of neighbourhood factors in mental health is inconclusive. We tested the hypothesis that high levels of ...

journal_title：Psychological medicine

authors： Fone D,White J,Farewell D,Kelly M,John G,Lloyd K,Williams G,Dunstan F

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Spontaneous movement disorders (SMDs), such as spontaneous dyskinesia and parkinsonism, have been described in patients with schizophrenia who have never been treated with antipsychotic medication. Their presence has been documented extensively in chronic schizophrenia but not at the time of illness onset. ...

journal_title：Psychological medicine

authors： Pappa S,Dazzan P

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The usefulness of any diagnostic scheme is directly related to its ability to provide clinically useful information on need for care. In this study, the clinical usefulness of dimensional and categorical representations of psychotic psychopathology were compared. METHOD:A total of 706 patients aged 16-65 ye...

journal_title：Psychological medicine

authors： Van Os J,Gilvarry C,Bale R,Van Horn E,Tattan T,White I,Murray R

更新日期：1999-05-01 00:00:00

abstract：:Age and sex-adjusted first admission rates for operationally-defined schizophrenia and other non-affective psychosis in different ethnic groups were calculated over the period 1988-1992 in a defined catchment area in South London. Standardized rates for schizophrenia, corrected for age- and gender-related under-report...

journal_title：Psychological medicine

authors： Van OS J,Castle DJ,Takei N,Der G,Murray RM

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Belief inflexibility is a thinking style observed in patients with schizophrenia, in which patients tend to refute evidence that runs counter to their prior beliefs. This bias has been related to a dominance of prior expectations (prior beliefs) over incoming sensory evidence. In this study we investigated t...

journal_title：Psychological medicine

authors： Barbalat G,Rouault M,Bazargani N,Shergill S,Blakemore SJ

更新日期：2012-11-01 00:00:00

abstract：:The persistence of psychosis at a high and relatively constant prevalence in the various populations of the world is rendered difficult to explain by the absence of identified environmental precipitants and by reduced fertility of affected individuals. The problem is not confined to schizophrenia but applies also to a...

journal_title：Psychological medicine

authors： Crow TJ

更新日期：1987-11-01 00:00:00

abstract：:In an earlier paper we found that a model of depression developed on a sample of women in a London population was confirmed in a female population in the Outer Hebrides. Differences in the rates of onset and chronic cases between the two populations, however, suggested that the Scottish women might be more likely to b...

journal_title：Psychological medicine

authors： Prudo R,Brown GW,Harris T,Dowland J

更新日期：1981-08-01 00:00:00