The Epstein-Barr virus BRRF2 gene product is involved in viral progeny production.

abstract：:The heptauridine tract at each gene end and intergenic region (IGR) at the gene junctions of vesicular stomatitis virus (VSV) have effects on synthesis of the downstream mRNA, independent of their respective roles in termination of the upstream mRNA. To investigate the role of the U tract and the IGR in downstream gen...

journal_title：Virology

authors： Hinzman EE,Barr JN,Wertz GW

更新日期：2008-10-25 00:00:00

abstract：:The Autographa californica M nucleopolyhedrovirus (AcMNPV) viral fibroblast growth factor (vFGF) has functional parallels to cellular FGFs. Deletion of the AcMNPV vfgf has no obvious phenotype in cell culture but delays the time of insect death. Here, we determined vFGF production during virus infection. vFGF was dete...

journal_title：Virology

authors： Lehiy CJ,Martinez O,Passarelli AL

更新日期：2009-12-05 00:00:00

abstract：:Woodchuck hepatitis core antigen (WHcAg) particles purified from the liver of chronically infected animals were used for monoclonal antibody production. Most of the putative clones demonstrated anti-WHc specificity. However, the supernatants from several putative clones bound X antigen sequences from woodchuck hepatit...

journal_title：Virology

authors： Feitelson MA,Clayton MM,Phimister B

更新日期：1990-07-01 00:00:00

abstract：:The subgroup II luteovirus barley yellow dwarf virus-RPV (BYDV-RPV) acts as a helper virus for a satellite RNA (satRPV RNA). The subgroup II luteovirus beet western yellows virus (BWYV) and the ST9-associated RNA (ST9a RNA), a BWYV-associated RNA that encodes a polymerase similar to those of subgroup I luteoviruses, w...

journal_title：Virology

authors： Rasochová L,Passmore BK,Falk BW,Miller WA

更新日期：1997-05-12 00:00:00

abstract：:There is growing evidence that the receptor-binding characteristics of influenza viruses are affected by the host-dependent glycosylation of viral hemagglutinin (HA). To better understand these effects, we propagated two variants of the human influenza virus USSR/90/77 (which differed by the mutation Asn131 reversible...

journal_title：Virology

authors： Gambaryan AS,Marinina VP,Tuzikov AB,Bovin NV,Rudneva IA,Sinitsyn BV,Shilov AA,Matrosovich MN

更新日期：1998-08-01 00:00:00

abstract：:The 380-kb chlorella virus NY-2A genome is highly methylated; 45% of the cytosines are 5-methylcytosine (5mC) and 37% of the adenines are N6-methyladenine (6mA). Based on the sensitivity/resistance of NY-2A DNA to 80 methylation-sensitive DNA restriction endonucleases, the virus is predicted to encode at least 10 DNA ...

journal_title：Virology

authors： Zhang Y,Nelson M,Nietfeldt J,Xia Y,Burbank D,Ropp S,Van Etten JL

更新日期：1998-01-20 00:00:00

abstract：:Retroviruses can be grouped by viral interference measurements into classes which use common cell surface receptors. We previously tested a large number of isolates of mink cell focus-inducing (MCF) murine leukemia viruses (MuLVs), and reported that all of them share a distinct receptor on NIH/3T3 cells (A. Rein, Viro...

journal_title：Virology

authors： Rein A,Schultz A

更新日期：1984-07-15 00:00:00

abstract：:We demonstrate that the AL2 gene of Cabbage leaf curl virus (CaLCuV) activates the CP promoter in mesophyll and acts to derepress the promoter in vascular tissue, similar to that observed for Tomato golden mosaic virus (TGMV). Binding studies indicate that sequences mediating repression and activation of the TGMV and ...

journal_title：Virology

authors： Lacatus G,Sunter G

更新日期：2008-06-20 00:00:00

abstract：:Wild-type vaccinia virus WR strain forms non-fusogenic (F-) large plaques and is hemagglutinin positive (HA+) under normal conditions of virus infection. We have analyzed a collection of spontaneous, highly attenuated mutants of vaccinia virus isolated from persistently infected Friend erythroleukemia cells (E. Paez, ...

journal_title：Virology

authors： Ortiz MA,Paez E

更新日期：1994-01-01 00:00:00

abstract：:The antigenic structure of the VP4 protein of human rotavirus (HRV) strains Wa and ST3 was studied by using a panel of Wa- and ST3-derived VP4-specific neutralizing monoclonal antibodies (NMAbs) and NMAb-resistant variants. The VP4-coding genes from three Wa and three ST3 variants were sequenced. For Wa VP4, one homot...

journal_title：Virology

authors： Padilla-Noriega L,Dunn SJ,López S,Greenberg HB,Arias CF

更新日期：1995-01-10 00:00:00

abstract：:The protruding (P) domain of norovirus VP1 is responsible for immune recognition and host receptor interaction. Our previous studies have demonstrated that a modification of the ends of the P domain affects the conformation and/or function of the P protein. An expression of the P domain with or without the hinge, or w...

journal_title：Virology

authors： Tan M,Fang PA,Xia M,Chachiyo T,Jiang W,Jiang X

更新日期：2011-02-20 00:00:00

abstract：:SV(PZF) is a mutant of Sindbis virus (SV) which we selected on the basis of its ability to replicate in mosquito cells treated with pyrazofurin (PZF), a drug which inhibits pyrimidine nucleotide biosynthesis (Lin et al., 2000, Virology 272, 61-71). Three mutations, A6627U, A7543U, and C7593A, were identified in the ns...

journal_title：Virology

authors： Lin YH,Simmonds HA,Stollar V

更新日期：2002-01-05 00:00:00

abstract：:Hepatitis B virus large surface protein has the unusual property of accumulating in a particulate form within a preGolgi compartment, leading to marked proliferation of intracellular membranes. We show here that large surface protein activates the promoters for two lipogenic genes that code for farnesyl diphosphate sy...

journal_title：Virology

authors： Foo NC,Yen TS

更新日期：2000-04-10 00:00:00

abstract：:Deletion of the nef gene results in viral attenuation and confers protection against challenge with wild-type simian immunodeficiency virus in macaques. Regarding HIV-1 infection, a few long-term nonprogressors (LTNP) with nef deletions have been described. In this study, the nef genes of a group of seven LTNP and eig...

journal_title：Virology

authors： Brambilla A,Turchetto L,Gatti A,Bovolenta C,Veglia F,Santagostino E,Gringeri A,Clementi M,Poli G,Bagnarelli P,Vicenzi E

更新日期：1999-07-05 00:00:00

abstract：:A plasmid-based transfection system capable of generating infectious porcine circovirus type 2 (PCV2) was established. This system was then used in mutagenesis studies to investigate the involvement of a "conserved" nonanucleotide (which constitutes a portion of the loop sequence) located at the origin of DNA replicat...

journal_title：Virology

authors： Cheung AK

更新日期：2004-06-20 00:00:00

abstract：:In response to oncogenic insults, normal human cells execute a defense response that culminates in cellular suicide, apoptosis. Normal human diploid fibroblasts expressing the human papillomavirus type 16 (HPV-16) E7 oncoprotein are predisposed to apoptosis when they are deprived of growth factors. Even though a domin...

journal_title：Virology

authors： Eichten A,Rud DS,Grace M,Piboonniyom SO,Zacny V,Münger K

更新日期：2004-02-05 00:00:00

abstract：:Essential host cofactors in retrovirus replication bind cis-acting sequences in the 5'untranslated region (UTR). Although host RBPs are crucial to all aspects of virus biology, elucidating their roles in replication remains a challenge to the field. Here RNA affinity-coupled-proteomics generated a comprehensive, unbia...

journal_title：Virology

authors： Stake M,Singh D,Singh G,Marcela Hernandez J,Kaddis Maldonado R,Parent LJ,Boris-Lawrie K

更新日期：2015-12-01 00:00:00

abstract：:The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) occlusion-derived virus (ODV) envelope protein ODV-E56 is essential for oral infection of larvae of Heliothis virescens. Bioassays with recombinant clones of AcMNPV lacking a functional odv-e56 gene showed that ODV-E56 was required for infectivity of bo...

journal_title：Virology

authors： Sparks WO,Harrison RL,Bonning BC

更新日期：2011-01-05 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus origin-dependent DNA replication requires the core replication proteins plus K-Rta and K-bZIP. To determine which K-bZIP protein domains contribute to oriLyt-dependent DNA replication and facilitate suppression of K-Rta-mediated transcriptional activation, we generated a series ...

journal_title：Virology

authors： Rossetto C,Gao Y,Yamboliev I,Papousková I,Pari G

更新日期：2007-12-20 00:00:00

abstract：:Bacteriophage phi 29 DNA polymerase is sensitive to aphidicolin (APH). DNA polymerase of the APH-resistant mutant, APHr71, was more sensitive to phosphonoacetic acid and butylphenyldeoxyguanosine 5'triphosphate than the wild type. Nucleotide sequence analysis revealed a single transition of G at nucleotide 562 to A in...

journal_title：Virology

authors： Matsumoto K,Kim CI,Kobayashi H,Kanehiro H,Hirokawa H

更新日期：1990-09-01 00:00:00

abstract：:In this study we have used an expression system based on Semliki Forest virus (SFV) to study assembly and intracellular localization of certain capsid proteins of rotavirus in neurons and mammalian epithelial cells. The complete genes of vp2 (vp2A) and vp6 (vp6A) of group A rotavirus (SA-11) and gene 5 encoding vp6 (v...

journal_title：Virology

authors： Nilsson M,von Bonsdorff CH,Weclewicz K,Cohen J,Svensson L

更新日期：1998-03-15 00:00:00

abstract：:Adsorption and one-step growth experiments performed with blue-green algal virus (BGAV) LPP-1 under normal conditions revealed a slow adsorption rate, in comparison with bacteriophage systems, followed by a 7-hour latent period. The burst size was approximately 100 virus particles per cell. The molecular weight of the...

journal_title：Virology

authors： Goldstein DA,Bendet IJ,Lauffer MA,Smith KM

更新日期：1967-08-01 00:00:00

abstract：:Adenovirus vectors are known to induce certain genes and impact innate response networks, but a broad understanding of this process and its mechanisms is currently lacking. For this reason, we chose to investigate and characterize Ad innate immunity using homogeneous, primary MEF cells replete with all the elements of...

journal_title：Virology

authors： Hartman ZC,Black EP,Amalfitano A

更新日期：2007-02-20 00:00:00

abstract：:Incubation of membrane vesicles from normal and Rous sarcoma virus-transformed chick embryo fibroblasts (CEF) with [gamma-32P]ATP resulted in the phosphorylation of a large number of proteins. The major differences observed between the membrane vesicles of untransformed and transformed cells were: (1) a 5- to 10-fold ...

journal_title：Virology

authors： Garber EA,Krueger JG,Hanafusa H,Goldberg AR

更新日期：1983-04-15 00:00:00

abstract：:V-CATH, a cathepsin L-like cysteine protease encoded by the baculovirus Autographa californica M nucleopolyhedrovirus, has been shown to play an essential role in host liquefaction. Similar to cellular cathepsin L, V-CATH is synthesized as an inactive proenzyme and is activated by cleavage of the propeptide. Previous ...

journal_title：Virology

authors： Hom LG,Ohkawa T,Trudeau D,Volkman LE

更新日期：2002-05-10 00:00:00

abstract：:Activation of the minute virus of mice (MVM) P4 promoter is a key step in the life cycle of the virus and is completely dependent on host transcription factors. Since transcription-factor composition varies widely in different cell types, there is the possibility that only some cell types in the host organism have the...

journal_title：Virology

authors： Davis C,Segev-Amzaleg N,Rotem I,Mincberg M,Amir N,Sivan S,Gitelman I,Tal J

更新日期：2003-02-15 00:00:00

abstract：:The mechanism by which lentivirus envelope (Env) glycoproteins are packaged into budding virions is poorly understood. Simian immunodeficiency virus (SIV) contains an Env protein with an unusually long cytoplasmic tail. To investigate the role of this domain in the incorporation of the SIV Env into virions, we generat...

journal_title：Virology

authors： Celma CC,Manrique JM,Affranchino JL,Hunter E,González SA

更新日期：2001-05-10 00:00:00

abstract：:The V protein of Sendai virus (SeV) is nonessential for virus replication in cell culture but indispensable for viral pathogenicity in mice. At the C terminus of the V protein, there are amino acid residues conserved among the members of the Paramyxovinae subfamily that are clustered in three regions: region I, just d...

journal_title：Virology

authors： Fukuhara N,Huang C,Kiyotani K,Yoshida T,Sakaguchi T

更新日期：2002-08-01 00:00:00

abstract：:The amino acid sequence of the coat protein of wild-type cowpea chlorotic mottle virus has been nearly completely determined by direct methods. The sites of amino acid replacements were identified in the coat proteins of an oxidation-sensitive mutant, a temperature-sensitive mutant, and a salt-stable mutant. The repla...

journal_title：Virology

authors： Rees MW,Short MN

更新日期：1982-06-01 00:00:00

abstract：:Selection of high-growth virus variants of strain B/Victoria/504/2000 by serial passage in eggs resulted in three amino acid substitutions, G141E, R162M, and D196Y, in the vicinity of the receptor-binding pocket of viral hemagglutinin. Virus variants containing the identified amino acid substitutions, individually or ...

journal_title：Virology

authors： Lugovtsev VY,Smith DF,Weir JP

更新日期：2009-11-25 00:00:00