Aphidicolin-resistant DNA polymerase of bacteriophage phi 29 APHr71 mutant is hypersensitive to phosphonoacetic acid and butylphenyldeoxyguanosine 5'-triphosphate.

abstract：:The epithelium of the cervix uteri has been reported to be frequently coinfected with both human papillomaviruses (HPV) and helper virus-dependent adenoassociated viruses (AAV). Seroepidemiological data suggest that AAV infection could inhibit cervical cancer that is caused by specific ("high-risk") types of papilloma...

journal_title：Virology

authors： Walz CM,Correa-Ochoa MM,Müller M,Schlehofer JR

更新日期：2002-02-01 00:00:00

abstract：:Significant economic losses in the poultry industries have resulted from H9N2 low pathogenic avian influenza virus infections across North Africa, the Middle East and Asia. The present study investigated the evolutionary dynamics of H9N2 viruses circulating in Korea from 1996 to 2012. Our analysis of viral population ...

journal_title：Virology

authors： Lee DH,Fusaro A,Song CS,Suarez DL,Swayne DE

更新日期：2016-01-15 00:00:00

abstract：:To comprehensively understand the endocytosis of Sapelovirus A (PSV) entry into PK-15 cells, we studied PSV infection in the context of cell perturbations through drug inhibition, siRNA silencing and overexpression of dominant negative (DN) mutants. We showed here that PSV infection of PK-15 cells was unaffected by pr...

journal_title：Virology

authors： Zhao T,Cui L,Yu X,Zhang Z,Shen X,Hua X

更新日期：2019-03-01 00:00:00

abstract：:We have recently described the cloning of a portion of the hepatitis E virus (HEV) and confirmed its etiologic association with enterically transmitted (waterborne, epidemic) non-A, non-B hepatitis. The virus consists of a single-stranded, positive-sense RNA genome of approximately 7.5 kb, with a polyadenylated 3' end...

journal_title：Virology

authors： Tam AW,Smith MM,Guerra ME,Huang CC,Bradley DW,Fry KE,Reyes GR

更新日期：1991-11-01 00:00:00

abstract：:The second smallest subgenomic messenger RNA, mRNA5, of the coronavirus infectious bronchitis virus includes in its "5' unique region" two separate open reading frames (5a and 5b), whose coding function has not so far been established, and thus it may represent a dicistronic messenger RNA. We report here that two poly...

journal_title：Virology

authors： Liu DX,Inglis SC

更新日期：1992-01-01 00:00:00

abstract：:We report the construction of herpes simplex virus 1 recombinants from which all or part of the coding sequences of four open reading frames have been deleted. In recombinants R7101 and R7108, the BamHI D' fragment containing the coding sequences of the dUTPase gene and the promoter-regulatory domain of a late gene wa...

journal_title：Virology

authors： Barker DE,Roizman B

更新日期：1990-08-01 00:00:00

abstract：:Putative replication complexes of cauliflower mosaic virus (CaMV) which resemble hepatitis B virus replication complexes in several respects have been identified. The CaMV replication complexes contain a heterogeneous population of minus-strand DNA ranging in size from less than 600 nucleotides to full genome length o...

journal_title：Virology

authors： Marsh L,Kuzj A,Guilfoyle T

更新日期：1985-05-01 00:00:00

abstract：:Proteins of an aquareovirus isolated from striped bass (SBR strain) were examined. Twelve viral-specific proteins ranging in molecular weight from approximately 130 to 15 kDa were identified in infected cells. Purified virions and infected cell lysates were used to characterize the structural and nonstructural protein...

journal_title：Virology

authors： Subramanian K,McPhillips TH,Samal SK

更新日期：1994-11-15 00:00:00

abstract：:Glycoprotein D (gD) of herpes simplex virus type 1 (HSV-1) plays a key role in multiple events during infection including virus entry, cell-to-cell spread, and virus-induced syncytia formation. Here, we provide evidence that an arginine/lysine cluster located at the transmembrane-cytoplasm interface of gD critically c...

journal_title：Virology

authors： Carmichael JC,Starkey J,Zhang D,Sarfo A,Chadha P,Wills JW,Han J

更新日期：2019-01-15 00:00:00

abstract：:The function of rice dwarf virus segment 11 and the corresponding segments of other phytoreoviruses is not yet determined. The amino acid sequence of Pns11, encoded by segment 11, contains a putative zinc finger and five flanking basic regions at the C-terminus. The full-length Pns11 protein and three truncated deriva...

journal_title：Virology

authors： Xu H,Li Y,Mao Z,Li Y,Wu Z,Qu L,An C,Ming X,Schiemann J,Casper R,Chen Z

更新日期：1998-01-20 00:00:00

abstract：:The amino acid sequence of the fiber from adenovirus type 5 has been deduced from the nucleotide sequence of the fiber gene. This sequence is compared with that of adenovirus type 2, a closely related serotype. We find 69% homology for the fiber protein whereas the known nonstructural proteins of these two serotypes h...

journal_title：Virology

authors： Chroboczek J,Jacrot B

更新日期：1987-12-01 00:00:00

abstract：:ICP27 is an essential herpes simplex virus type 1 (HSV-1) nuclear protein which regulates viral early and late genes during infection. The exact mechanism by which ICP27 modulates viral gene expression is unknown, but considerable evidence suggests that it functions posttranscriptionally. In this study, we have asked ...

journal_title：Virology

authors： Mears WE,Rice SA

更新日期：1998-03-01 00:00:00

abstract：:A system to associate specific genome segments with viral phenotypes and to study factors influencing genome reassortment was developed for tomato spotted wilt Tospovirus (TSWV). Reassortant isolates were generated by co-inoculating a TSWV isolate, TSWV-D, with TSWV-10 or TSWV-MD. The parental origin of each genome se...

journal_title：Virology

authors： Qiu WP,Geske SM,Hickey CM,Moyer JW

更新日期：1998-04-25 00:00:00

abstract：:We have used a yeast two-hybrid system to identify a baculoviral gene encoding a protein kinase-interacting protein (PKIP). The pkip gene is located at 15.8-16.2 m.u (map units) and represents ORF 24 in the sequence of Ayres et al. (1994) of the Autographa californica nuclear polyhedrosis virus. PKIP is a 19.2-kDa pro...

journal_title：Virology

authors： Fan X,McLachlin JR,Weaver RF

更新日期：1998-01-20 00:00:00

abstract：:The amino acid sequence of the coat protein of wild-type cowpea chlorotic mottle virus has been nearly completely determined by direct methods. The sites of amino acid replacements were identified in the coat proteins of an oxidation-sensitive mutant, a temperature-sensitive mutant, and a salt-stable mutant. The repla...

journal_title：Virology

authors： Rees MW,Short MN

更新日期：1982-06-01 00:00:00

abstract：:High levels of nonfused chloramphenicol acetyltransferase, beta-galactosidase, and beta-glucuronidase expressed under the control of new vector constructs of the polyhedrin promoter in Spodoptera frugiperda cells infected with Autographa californica nuclear polyhedrosis virus were investigated by SDS-PAGE and RNA dot ...

journal_title：Virology

authors： Luckow VA,Summers MD

更新日期：1989-05-01 00:00:00

abstract：:The initiation of reverse transcription of the human immunodeficiency virus type 1 (HIV-1) genome requires cellular tRNA(Lys,3) as a primer and occurs at a site in the viral RNA genome, designated as the primer binding site (PBS), which is complementary to the 3'-terminal 18 nucleotides of tRNA(Lys,3). We previously d...

journal_title：Virology

authors： Zhang Z,Kang SM,LeBlanc A,Hajduk SL,Morrow CD

更新日期：1996-12-15 00:00:00

abstract：:Dengue virus (DENV) is an arbovirus that belongs to the Flaviviridae family. Studies reveal that peptides secreted by amphibians have many functions, such as antiviral and antimicrobial activities. As there is no antiviral drug effective against the DENV, the antiviral activity of a synthetic peptide called HS-1, deri...

journal_title：Virology

authors： Monteiro JMC,Oliveira MD,Dias RS,Nacif-Marçal L,Feio RN,Ferreira SO,Oliveira LL,Silva CC,Paula SO

更新日期：2018-01-15 00:00:00

abstract：:Persistent infection with the Edmonston strain of measles virus (MV) has been established in IC-21 cells, an immortalized murine macrophage cell line. Persistence was established immediately without syncytia formation or cytopathic effects. MV was expressed in the majority of the cells as evidenced by immunofluorescen...

journal_title：Virology

authors： Goldman MB,Buckthal DJ,Picciotto S,O'Bryan TA,Goldman JN

更新日期：1995-02-20 00:00:00

abstract：:Our study reports the occurrence of HIV-1 insertional activation events in vivo. Using a previously described PCR assay, small aliquots of broncho-alveolar lavage (BAL) cells obtained from AIDS patients were analyzed. Nine percent (5/54) of the aliquots contained proviral-host sequence transcripts indicating HIV-1 pro...

journal_title：Virology

authors： Raineri I,Solèr M,Senn HP

更新日期：1995-04-01 00:00:00

abstract：:Cell-mediated immunity plays a key role in the regression of papillomavirus-induced warts and intra-epithelial lesions but the target antigens that induce this response are not clear. Canine oral papillomavirus (COPV) infection of the oral cavity in dogs is a well-characterized model of mucosal papillomavirus infectio...

journal_title：Virology

authors： Jain S,Moore RA,Anderson DM,Gough GW,Stanley MA

更新日期：2006-12-05 00:00:00

abstract：:The envelope proteins of hepatitis C virus (HCV) are the likely targets of neutralizing antibodies and their molecular and functional characterization is relevant for vaccine development. We previously showed that surface-expressed E2 is a better immunogen than intracellular E2 and, therefore, we were interested in ex...

journal_title：Virology

authors： Forns X,Allander T,Rohwer-Nutter P,Bukh J

更新日期：2000-08-15 00:00:00

abstract：:Human keratinocytes (HKc) immortalized by human papillomavirus type 16 DNA (HKc/HPV16) progress toward malignancy through growth factor-independent (HKc/GFI) and differentiation-resistant stages (HKc/DR). This progression is associated with a loss of sensitivity to growth inhibition by both all-trans-retinoic acid (RA...

journal_title：Virology

authors： Mi Y,Borger DR,Fernandes PR,Pirisi L,Creek KE

更新日期：2000-05-10 00:00:00

abstract：:Virus like particles (17 nm in diameter) associated with maize white line mosaic virus (MWLMV) were shown to be a satellite virus of MWLMV (SV-MWLMV) on the basis of the following properties: (1) The SV-MWLMV was dependent upon the presence of MWLMV for replication in maize, while the latter virus could replicate inde...

journal_title：Virology

authors： Zhang L,Zitter TA,Palukaitis P

更新日期：1991-02-01 00:00:00

abstract：:Human papillomaviruses (HPVs) are epitheliotropic viruses, and their life cycle is intimately linked to the stratification and differentiation state of the host epithelial tissues. Defining a role for the E5 gene product in the differentiation-dependent viral life cycle has been difficult due to the lack of a suitable...

journal_title：Virology

authors： Mayer TJ,Meyers C

更新日期：1998-09-01 00:00:00

abstract：:Replication of Tomato bushy stunt virus (TBSV) RNA takes place on the cytosolic membrane surface of peroxisomes in plants and in yeast, a model host. To identify the host proteins involved in assisting the peroxisomal localization of the tombusvirus p33 replication protein, we tested if p33 could bind directly to yeas...

journal_title：Virology

authors： Pathak KB,Sasvari Z,Nagy PD

更新日期：2008-09-30 00:00:00

abstract：:Previously we have reported that the essential 3a movement gene of icosahedral cowpea chlorotic mottle virus (CCMV) can be functionally replaced by the 30-kDa movement gene of rod-shaped sunn-hemp mosaic virus (SHMV). Because plant RNA viruses differ in requiring or not requiring coat protein for systemic infection, w...

journal_title：Virology

authors： De Jong W,Mise K,Chu A,Ahlquist P

更新日期：1997-05-26 00:00:00

abstract：:Previous serological studies of experimental infection with duck hepatitis B virus (DHBV) have shown that the outcome of infection depends largely on the age of the duck at the time of inoculation. To examine the hypothesis that decreased susceptibility with increased age might be due to the loss of the virus receptor...

journal_title：Virology

authors： Qiao M,Gowans EJ,Burrell CJ

更新日期：1992-02-01 00:00:00

abstract：:Open reading frame 89 (ORF89) is one of the three genes that are believed to be involved in the latent infection of white spot syndrome virus (WSSV). Here, we report the structure and functional characterization of ORF89. cDNA sequencing, 5' RLM-RACE, and 3' RLM-RACE showed that ORF89 gene is transcribed into an unspl...

journal_title：Virology

authors： Hossain MS,Khadijah S,Kwang J

更新日期：2004-07-20 00:00:00

abstract：:Packaging of lambda DNA is mediated by the phage-encoded enzyme, terminase, which acts at a site termed cos. cos consists of cosB, the site where terminase binds lambda DNA, and cosN, the site where nicks are introduced to generate the cohesive ends of virion DNA. cos contains multiple binding sites for gpNu1, the sma...

journal_title：Virology

authors： Yeo A,Kosturka LD,Feiss M

更新日期：1990-01-01 00:00:00