Abstract:
:We have used a yeast two-hybrid system to identify a baculoviral gene encoding a protein kinase-interacting protein (PKIP). The pkip gene is located at 15.8-16.2 m.u (map units) and represents ORF 24 in the sequence of Ayres et al. (1994) of the Autographa californica nuclear polyhedrosis virus. PKIP is a 19.2-kDa protein and appears to stimulate the activity of the viral protein kinase-1 in vitro. Northern blotting analysis revealed that pkip is a late gene. Attempts to plaque purify a pkip- virus were unsuccessful.
journal_name
Virologyjournal_title
Virologyauthors
Fan X,McLachlin JR,Weaver RFdoi
10.1006/viro.1997.8944subject
Has Abstractpub_date
1998-01-20 00:00:00pages
175-82issue
2eissn
0042-6822issn
1096-0341pii
S0042-6822(97)98944-3journal_volume
240pub_type
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