Abstract：
:Apoptosis stimulated by bacterial toxins is common during infection and is now considered important in disease processes. As a major human pathogen, Staphylococcus aureus also causes apoptosis during infection. In some diseases such as atopic dermatitis and sepsis, the apoptosis induced by S. aureus influences the severity and outcome of diseases. S. aureus has various toxins, many of which have reportedly triggered apoptosis. In this review, we focused on the apoptosis-inducing toxins secreted by S. aureus, and their underlying mechanisms. Novel therapies for cancer that utilized the reconstructed S. aureus toxins were also discussed.
journal_name
Microbiol Resjournal_title
Microbiological researchauthors
Zhang X,Hu X,Rao Xdoi
10.1016/j.micres.2017.08.006subject
Has Abstractpub_date
2017-12-01 00:00:00pages
19-24eissn
0944-5013issn
1618-0623pii
S0944-5013(17)30355-5journal_volume
205pub_type
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