Abstract:
:To clarify the organization of motor representations in posterior parietal cortex, we test how three motor variables (body side, body part, cognitive strategy) are coded in the human anterior intraparietal cortex. All tested movements were encoded, arguing against strict anatomical segregation of effectors. Single units coded for diverse conjunctions of variables, with different dimensions anatomically overlapping. Consistent with recent studies, neurons encoding body parts exhibited mixed selectivity. This mixed selectivity resulted in largely orthogonal coding of body parts, which "functionally segregate" the effector responses despite the high degree of anatomical overlap. Body side and strategy were not coded in a mixed manner as effector determined their organization. Mixed coding of some variables over others, what we term "partially mixed coding," argues that the type of functional encoding depends on the compared dimensions. This structure is advantageous for neuroprosthetics, allowing a single array to decode movements of a large extent of the body.
journal_name
Neuronjournal_title
Neuronauthors
Zhang CY,Aflalo T,Revechkis B,Rosario ER,Ouellette D,Pouratian N,Andersen RAdoi
10.1016/j.neuron.2017.06.040subject
Has Abstractpub_date
2017-08-02 00:00:00pages
697-708.e4issue
3eissn
0896-6273issn
1097-4199pii
S0896-6273(17)30592-5journal_volume
95pub_type
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