Transoral robotic total laryngopharyngectomy and free jejunal flap reconstruction for hypopharyngeal cancer.

abstract：:Periodontal infection may exacerbate during cancer therapy and may result in oral pain and infection, and systemic infection, which may cause morbidity and can lead to mortality in neutropenic cancer patients. Periodontal disease in head and neck cancer patients treated with radiation therapy may lead to acute and chr...

journal_title：Oral oncology

authors： Epstein JB,Stevenson-Moore P

更新日期：2001-12-01 00:00:00

abstract：:Large cell neuroendocrine carcinoma is a poorly differentiated neuroendocrine carcinoma that usually occurs in the lung. Although rare in the head and neck, salivary and mucosal subtypes are recognized. This article describes their characteristic light microscopic and immunohistochemical features and highlights the im...

journal_title：Oral oncology

authors： Kusafuka K,Ferlito A,Lewis JS Jr,Woolgar JA,Rinaldo A,Slootweg PJ,Gnepp DR,Devaney KO,Travis WD,Barnes L

更新日期：2012-03-01 00:00:00

abstract：:The purpose of this study was to assess the accuracy of this tissue staining assessment of surgical specimens in delineating deep surgical margins in oral cancer surgery. Fifteen patients who underwent surgery for oral carcinoma were included in the study. Once the tumor was resected, a vertical section of the surgica...

journal_title：Oral oncology

authors： Kurita H,Sakai H,Kamata T,Koike T,Kobayashi H,Kurashina K

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVES:It is well recognized that oral squamous cell carcinoma (OSCC) cases from Asia that are associated with betel quid chewing are phenotypically distinct to those from Western countries that are predominantly caused by smoking/drinking, but the molecular basis of these differences are largely unknown. The aim o...

journal_title：Oral oncology

authors： Saeed AA,Sims AH,Prime SS,Paterson I,Murray PG,Lopes VR

更新日期：2015-03-01 00:00:00

abstract：:The submental artery island flap (SIF) is gaining acceptance as a simple and reliable option in selected oral oncologic reconstructions. The present study aims to assess the usefulness of submental artery flap in oral reconstruction with respect to flap reliability, cosmesis, function, donor site morbidity and oncolog...

journal_title：Oral oncology

authors： Sebastian P,Thomas S,Varghese BT,Iype EM,Balagopal PG,Mathew PC

更新日期：2008-11-01 00:00:00

abstract：:We evaluated the prognostic significance of p34cdc2 expression in 50 tongue squamous cell carcinomas (SCC) using immunohistochemical methods. The p34cdc2 protein was expressed in 33 cases of 50 tumor tissues (66.0%), compared with 15 cases of 42 controlled epithelia (35.7%). The expression of p34cdc2 was significantly...

journal_title：Oral oncology

authors： Wada S,Yue L,Furuta I

更新日期：2004-02-01 00:00:00

abstract：:Oral cancer (OC), which is the most common form of head and neck cancers, has one of the lowest (~50%) overall 5-year survival rates. The main reasons for this high mortality rate are diagnosis of OC in advanced stages in most patients and spread to distant organs via lymph node metastasis. Many studies have shown tha...

journal_title：Oral oncology

authors： Barlak N,Capik O,Sanli F,Karatas OF

更新日期：2020-08-19 00:00:00

abstract：:The aim of this study was to define the appropriate fractionation interval between photodynamic therapies (PDTs) for enhanced anti-tumour effects on human oral squamous cell carcinoma (HOSCC). Reoxygenation of HOSCC and the proliferative kinetics of the tumour cells following PDT exposure were evaluated in terms of im...

journal_title：Oral oncology

authors： Togashi H,Uehara M,Ikeda H,Inokuchi T

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:Esophageal second primary tumors (SPTs) in head and neck cancer (HNC) patients is not uncommon. The impact of image-enhanced endoscopy (IEE) screening for esophageal SPT on the outcome of HNC patients has not been well clarified. METHODS AND METHODS:Patients with malignancies of the head and neck region and...

journal_title：Oral oncology

authors： Chung CS,Lo WC,Chen KC,Lin CL,Wen MH,Hsieh CH,Lin SC,Liao LJ

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:ICIs have expanded treatment options for HNSCC. A minority of the patients respond to these expensive treatments. PATIENTS AND METHODS:This is a single institutional retrospective review on 121 unresectable or metastatic HNSCC patients treated with ICIs. We predicted that inflammatory markers available thro...

journal_title：Oral oncology

authors： Bonomi M,Bhateja P,Issa M,Klamer B,Pan X,Blakaj A,Karivedu V,Mousa L,Mitchell D,Gamez M,Kang S,Seim NB,Old M,Carrau R,Rocco J,Blakaj D

更新日期：2020-11-01 00:00:00

abstract：:Oral malignant melanoma is uncommon, accounting for 1-8% of all malignant melanomas. All previous papers have reported small numbers of cases or have retrospectively reviewed case reports from the literature. The following case reports concern malignant melanoma of the oral cavity seen at the Instituto Nacional de Can...

journal_title：Oral oncology

authors： Lopez-Graniel CM,Ochoa-Carrillo FJ,Meneses-García A

更新日期：1999-07-01 00:00:00

abstract：:In this double-blind, randomized trial, we compared the clinical efficacy of intralesional vinblastine (VNB) and 3% sodium tetradecyl sulfate (STS) in the treatment of oral Kaposi's sarcoma (OKS). Subjects with OKS were randomly assigned to receive a single intralesional injection of either VNB or STS, at a standard d...

journal_title：Oral oncology

authors： Ramírez-Amador V,Esquivel-Pedraza L,Lozada-Nur F,De la Rosa-García E,Volkow-Fernández P,Súchil-Bernal L,Mohar A

更新日期：2002-07-01 00:00:00

abstract：:The purpose of this systematic review and meta-analysis was to evaluate the diagnostic value of salivary biological markers in the diagnosis of head and neck carcinoma. Studies were gathered by searching Cochrane, EMBASE, LILACS, MEDLINE, and PubMed. The references were also crosschecked and a partial grey literature ...

journal_title：Oral oncology

authors： Guerra EN,Acevedo AC,Leite AF,Gozal D,Chardin H,De Luca Canto G

更新日期：2015-09-01 00:00:00

abstract：:The aim of this study is to assess the impact of prognostic factors in patients with locoregionally advanced nasopharyngeal cancer (NPC), WHO type II-III, treated with two different radiation therapy (RT) schedules: standard radiation therapy (SRT), and accelerated hyperfractionated radiation therapy (HART), with or w...

journal_title：Oral oncology

authors： Franchin G,Vaccher E,Talamini R,Gobitti C,Minatel E,Politi D,Sartor G,Trovò MG,Barzan L

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:The main aim was to investigate the incidence of patient adherence to nutritional tube feeding recommendations in patients with head and neck cancer and to determine patient barriers to meeting tube feeding prescription. MATERIALS AND METHODS:This was an observational study from a randomised controlled tria...

journal_title：Oral oncology

authors： Brown T,Banks M,Hughes BGM,Lin C,Kenny L,Bauer J

更新日期：2017-09-01 00:00:00

abstract：:Betel quid (BQ) and matrix metalloproteinase-8 (MMP-8) play roles in oral diseases. Here, we analyzed the regulation of MMP-8 by BQ and its effect on cell migration. We found that BQ extract (BQE) increased the secretion of an 85kDa caseinolytic proteinase, specifically precipitated by an anti-MMP-8 antibody, in the c...

journal_title：Oral oncology

authors： Liu SY,Liu YC,Huang WT,Huang GC,Chen TC,Lin MH

更新日期：2007-11-01 00:00:00

abstract：:Recently, we reported the preliminary results of a prospective study on the possible premalignant character of oral lichen planus (OLP) and oral lichenoid lesions (OLL). Based on these data it was concluded that there was some but no convincing support for the hypothesis that patients with OLL have an increased risk o...

journal_title：Oral oncology

authors： van der Meij EH,Mast H,van der Waal I

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:There is a clinical need to improve outcomes for patients with locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN), especially in Human Papilloma Virus (HPV) negative and HPV positive subtypes with a significant history of tobacco use. In animal models bearing SCCHN, Cabazitaxel showed a...

journal_title：Oral oncology

authors： Camille N,Rozehnal J,Roy E,Uczkowski D,Olson A,Genden E,Teng M,Bakst R,Gupta V,Posner M,Misiukiewicz K

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:Adenoid cystic carcinoma (ACC) is one of the most common malignancies of salivary glands, characterized by poor prognosis, particularly due to pulmonary metastasis. We previously reported that transforming growth factor (TGF)-β1 promoted ACC cell migration and invasion via the Smad pathway in vitro. The aim ...

journal_title：Oral oncology

authors： Dong L,Ge XY,Wang YX,Yang LQ,Li SL,Yu GY,Gao Y,Fu J

更新日期：2013-11-01 00:00:00

abstract：:We investigated the presence of neural cell adhesion molecule (N-CAM) in the adenoid cystic carcinoma cell line CAC2 using immunofluorescence microscopy. Additionally, we analysed the role of laminin and type IV collagen in N-CAM expression. We demonstrated that cultured adenoid cystic carcinoma cells express N-CAM. C...

journal_title：Oral oncology

authors： França CM,Jaeger MM,Jaeger RG,Araújo NS

更新日期：2000-03-01 00:00:00

abstract：:In our previous study, we established an in vitro cellular carcinogenesis model of oral squamous cell carcinoma (OSCC), including a human immortalized oral epithelial cell (HIOEC) and a cancerous cell line (HB96). Microarray analysis showed that the gene encoding Yes-associated protein (YAP) was significantly increase...

journal_title：Oral oncology

authors： Zhang L,Ye DX,Pan HY,Wei KJ,Wang LZ,Wang XD,Shen GF,Zhang ZY

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:High risk human papillomavirus (HR-HPV) infection leads to a subgroup of oropharyngeal cancer (OPSCC) characterized by improved treatment response. However an universally accepted definition of an HR-HPV-attributable cancer is lacking. METHODS:Detailed, type-specific HPV antibody responses were analyzed by ...

journal_title：Oral oncology

authors： Broglie MA,Jochum W,Michel A,Waterboer T,Foerbs D,Schoenegg R,Stoeckli SJ,Pawlita M,Holzinger D

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the role of the extended Abbé flap in the reconstruction of complex midfacial defects (upper lip, nasal base and medial cheek). We describe our personal experience with this method and present some interesting aspects from the relevant literature. MATERIALS AND METHO...

journal_title：Oral oncology

authors： Mantsopoulos K,Iro H,Constantinidis J

更新日期：2020-01-01 00:00:00

abstract：:Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) generates microvascular parameters from the tracer kinetic analysis of a series of MRI images obtained in under 15 min. DCE-MRI parameters are associated with tumour hypoxia, which is well-established as a cause of treatment failure in head and neck squamo...

journal_title：Oral oncology

authors： Bernstein JM,Homer JJ,West CM

更新日期：2014-10-01 00:00:00

abstract：:Spindle-cell lipoma (SCL) is a distinct histological variant of lipoma. Clinically, it appears as a solitary, subcutaneous, circumscribed lesion. SCL accounts for about 1.5% of all adipocytic tumours. Only nine cases of intraoral SCL were found in the literature. Microscopically, mature adipocytes and spindle cells ar...

journal_title：Oral oncology

authors： Piattelli A,Rubini C,Fioroni M,Iezzi G

更新日期：2000-09-01 00:00:00

abstract：:The objective of this study was to analyze the role of adjuvant chemotherapy and prognostic factors in malignant mucosal melanoma of the head and neck (HNMM). Thirty-two patients with mucosal melanoma of the head and neck who received local treatment with or without adjuvant chemotherapy were reviewed. Clinicopatholog...

journal_title：Oral oncology

authors： Ahn HJ,Na II,Park YH,Cho SY,Lee BC,Lee GH,Koh JS,Lee YS,Shim YS,Kim YK,Kang HJ,Ryoo BY,Yang SH

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:The need to improve chemotherapeutic efficacy against head and neck squamous cell carcinomas (HNSCC) is well recognized. In this study, we investigated the potential of targeting the established tumor vasculature in combination with chemotherapy in head and neck cancer. METHODS:Experimental studies were carrie...

journal_title：Oral oncology

authors： Folaron M,Kalmuk J,Lockwood J,Frangou C,Vokes J,Turowski SG,Merzianu M,Rigual NR,Sullivan-Nasca M,Kuriakose MA,Hicks WL Jr,Singh AK,Seshadri M

更新日期：2013-09-01 00:00:00

abstract：:Histone deacetylases (HDACs) are enzymes that are involved in the remodeling of chromatin and play a key role in the epigenetic regulation of gene expression. In addition, the activity of non-histone proteins can be regulated through HDAC-mediated hypoacetylation. In recent years, inhibition of HDACs has emerged as a ...

journal_title：Oral oncology

authors： Iglesias-Linares A,Yañez-Vico RM,González-Moles MA

更新日期：2010-05-01 00:00:00

abstract：:Several reports have indicated that nuclear factor-kappa B (NF-κB) is constitutively activated in a variety of cancer cells including human oral squamous carcinoma cells, and play a key role in their growth and survival. Recent studies report that NF-κB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), inhibits proli...

journal_title：Oral oncology

authors： Yasuda A,Kondo S,Nagumo T,Tsukamoto H,Mukudai Y,Umezawa K,Shintani S

更新日期：2011-05-01 00:00:00

abstract：:Traumatic eosinophilic granuloma of the oral mucosa, also known as eosinophilic ulcer, is considered to be a reactive lesion of unknown aetiology. It usually presents as a tongue ulcer and injury has been considered to play a role in its cause. We present a 72-year-old man who had suffered multiple episodes of recurre...

journal_title：Oral oncology

authors： Ficarra G,Prignano F,Romagnoli P

更新日期：1997-09-01 00:00:00