Climbing and parallel fiber responses recorded intracellularly from Purkinje cell dendrites in guinea pig cerebellar slices.

Abstract:

:Climbing fiber responses (CFRs) evoked by white matter stimulation and parallel fiber responses (PFRs) elicited by the stimulation of the surface of the folium were compared using intracellular recording from the dendrites of Purkinje cells in the in vitro slice preparation of the guinea pig cerebellum. Intracellular injection of caesium ions allowed Purkinje cell dendrites to depolarize to a range of -20 to +30 mV, and to reverse both CFR and PFR. The mean reversal potential for the CFR was less negative than for the PFR. CF exhibited a depleting property of a neurotransmitter. The contribution of the Ca-component at the rising phase of CFR was discussed.

journal_name

Brain Res

journal_title

Brain research

authors

Kimura H,Okamoto K,Sakai Y

doi

10.1016/0006-8993(85)90439-1

subject

Has Abstract

pub_date

1985-12-02 00:00:00

pages

213-9

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(85)90439-1

journal_volume

348

pub_type

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