Incidence of tonsillar cancer in northern Sweden: Impact of human papilloma virus.

abstract：:The Mantle Cell Lymphoma International Prognostic Index (MIPI) combines four factors to differentiate low-, intermediate- and high-risk prognostic groups in advanced mantle cell lymphoma using data from patients treated in clinical trials. To evaluate its use in routine practice, we applied the simplified index retros...

journal_title：Oncology letters

authors： Lim SY,Horsman JM,Hancock BW

更新日期：2010-01-01 00:00:00

abstract：:To assess the influence of microRNA-183 (miR-183) on the migration and invasion of A375 human melanoma cells, an A375 cell line with stable miR-183 overexpression or knockdown was constructed using lentiviral transfection. The change of miR-183 expression in these cells and in non-transfected controls was verified usi...

journal_title：Oncology letters

authors： Zhang Y,Wang G

更新日期：2019-01-01 00:00:00

abstract：:Cancer is a histologically and genetically heterogeneous population of tumor cells that exhibits distinct molecular profiles determined by epigenetic alterations. P-element-induced wimpy testis (PIWI) proteins in complex with PIWI-interacting RNA (piRNA) have been previously demonstrated to be involved in epigenetic r...

journal_title：Oncology letters

authors： Litwin M,Szczepańska-Buda A,Piotrowska A,Dzięgiel P,Witkiewicz W

更新日期：2017-05-01 00:00:00

abstract：:Hypericum ascyron L. (Great St. Johnswort), which belongs to the Hypericaceae family, has been used for the treatment of hematemesis, metrorrhagia, rheumatism, swelling, stomach ache, abscesses, dysentery and irregular menstruation for >2,000 years in China. The aim of the present study was to clarify the anticancer a...

journal_title：Oncology letters

authors： Li XM,Luo XG,He JF,Wang N,Zhou H,Yang PL,Zhang TC

更新日期：2018-03-01 00:00:00

abstract：:Special AT-rich sequence binding protein 1 (SATB1) has regulatory effects on gene expression and appears to play an important role in tumor progression. The present study screened the promoter region of the SATB1 gene for polymorphisms, evaluated the corresponding haplotypes regarding alterations in promoter activity ...

journal_title：Oncology letters

authors： Heubner M,Kimmig R,Aktas B,Siffert W,Frey UH

更新日期：2014-06-01 00:00:00

abstract：:Previously, the preoperative neutrophil-to-lymphocyte ratio (NLR) has been demonstrated to be a beneficial prognostic marker in patients with upper tract urothelial carcinoma (UTUC). However, to the best of our knowledge, the postoperative NLR has rarely been investigated. Therefore, the present study evaluated the pr...

journal_title：Oncology letters

authors： Nishihara K,Suekane S,Ueda K,Nakiri M,Matsuo M,Igawa T

更新日期：2019-06-01 00:00:00

abstract：:An alteration in the mitochondrial DNA (mtDNA) copy number has been detected in numerous human cancers. However, certain changes in the mtDNA copy number that occur during the initiation and progression of gastric cancer remain undetected. In the present study, using quantitative PCR analysis, the quantitative changes...

journal_title：Oncology letters

authors： Wen SL,Zhang F,Feng S

更新日期：2013-10-01 00:00:00

abstract：:We present the case of a patient with a solitary left frontoparietal brain metastasis of melanoma previously treated with surgery. Three months later, the patient was admitted to the emergency room in a confusional state with meningeal signs. A cerebrospinal fluid (CSF) test and magnetic resonance imaging findings sug...

journal_title：Oncology letters

authors： Moyano MS,Gutiérrez-Gutiérrez G,Rodríguez-Esteban I,Crespo GS,Casado E

更新日期：2010-11-01 00:00:00

abstract：:Giant cell tumor of bone (GCTB) is a primary benign bone tumor with a locally aggressive character. Definitive descriptions of the site of origin for this type of tumor are not available. The aim of the present study was to evaluate the site of origin of GCTB of long bones with regards to epiphyseal lines by means of ...

journal_title：Oncology letters

authors： Futamura N,Urakawa H,Tsukushi S,Arai E,Kozawa E,Ishiguro N,Nishida Y

更新日期：2016-04-01 00:00:00

abstract：:The role of tumor-infiltrating lymphocytes (TILs) suggests that cancer is a disease with not only a genetic, but also an immunological basis. Additionally, immune cell infiltration is an important feature of oral cancer. C-X-C motif chemokine ligand 12 (CXCL12) serves an important role in immune suppression in the tum...

journal_title：Oncology letters

authors： Zhang B,Wu C,Zhang Z,Yan K,Li C,Li Y,Li L

更新日期：2019-08-01 00:00:00

abstract：:Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, fast-growing, benign tumor originating from the neural crest. The tumor most often occurs during the first year of life. The predilection site of MNTI is the anterior maxilla, whereas lesions of the mandible are uncommon and account for only 6% of all cases....

journal_title：Oncology letters

authors： Cui Y,Mao Z,Liao C

更新日期：2015-01-01 00:00:00

abstract：:Lymph node metastasis is the primary site of metastasis for patients with gallbladder cancer (GBC). Vascular endothelial growth factor-C (VEGF-C) has been implicated in the control of lymphangiogenesis and lymph node metastasis in various malignant tumors. However, the function of circulating VEGF-C is unclear and it ...

journal_title：Oncology letters

authors： Jiang L,Liu M,Cai X,Xie L,She F,Chen Y

更新日期：2018-11-01 00:00:00

abstract：:Isolated cortical vein thrombosis (ICoVT) is a rare form of cerebral venous thrombosis and is easily misdiagnosed as brain tumor due to its atypical clinical presentations and radiological findings similar to brain tumors. The present study focused on 4 patients with ICoVT, 2 men and 2 women. In the 2 male patients, t...

journal_title：Oncology letters

authors： Yu Y,Ren M,Yao S,Zhao X,Qi X

更新日期：2016-01-01 00:00:00

abstract：:The present study was undertaken to characterize carbon and iron ion radiation-induced adverse biological effects in terms of toxicity and transformation in vitro. HTori-3 human thyroid epithelial cells were irradiated with 0.3-GeV/n (13.6 KeV/µm) carbon ions and 1-GeV/n (150 KeV/µm) iron ions, both of which represent...

journal_title：Oncology letters

authors： Zhou Z,Ware JH,Kennedy AR

更新日期：2011-09-01 00:00:00

abstract：:Cancer affects multiple organs in the body Malignant melanoma involves the invasion of skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of cutaneous malignant melanoma is on the increase worldwide and is a major concern in current research. The increase is associated with UV irradiation-i...

journal_title：Oncology letters

authors： Zhang XY,Zhang PY

更新日期：2016-11-01 00:00:00

abstract：:Selective amino acid restriction targets mitochondria to induce apoptosis of DU145 and PC3 prostate cancer cells. Biochemical assays and flow cytometry were uitilized to analyze the glucose consumption, lactate production, pyruvate dehydrogenase (PDH), nicotinamide adenine dinucleotide (NAD)/NADH and nicotinamide aden...

journal_title：Oncology letters

authors： Liu X,Fu YM,Meadows GG

更新日期：2011-01-18 00:00:00

abstract：:Poor nutritional status is common in ovarian cancer. It is well known that the nutritional status of a patient with malignant disease is associated with survival, and that it can be assessed by serum levels of rapid turnover proteins (RTPs), such as retinol binding protein, prealbumin and transferrin. Systemic inflamm...

journal_title：Oncology letters

authors： Watanabe T,Shibata M,Nishiyama H,Soeda S,Furukawa S,Gonda K,Takenoshita S,Fujimori K

更新日期：2014-02-01 00:00:00

abstract：:A 72-year-old man initially presented with lumbar and right chest pain, but was later found out to also have an elevated prostate-specific antigen (PSA) level at 2,000.0 ng/ml. Further evaluation disclosed metastatic prostate cancer involving the bones and lymph nodes. The patient was initially treated with combined a...

journal_title：Oncology letters

authors： Kato T,Komiya A,Yuasa J,Kaga K,Kaga M,Kojima S,Naya Y,Isaka S

更新日期：2018-02-01 00:00:00

abstract：:Nucleobindin 2 (NUCB2) is mainly expressed in the hypothalamic nuclei and has a proven role in energy homeostasis. It has also been recently reported to have a key role in tumor progression. However, the clinical significance of NUCB2 in colorectal cancer (CRC) remains unknown. In the present study, the level of NUCB2...

journal_title：Oncology letters

authors： Xie J,Chen L,Chen W

更新日期：2018-06-01 00:00:00

abstract：:In the present study, a low molecular weight polysaccharide, ABP-AW1, isolated from Agaricus blazei Murill was assessed for its potential adjuvant activity. ABP-AW1 is considered to create a 'depot' of antigen at a subcutaneous injection site. ICR mice were immunized with 100 μg ovalbumin (OVA) alone or with 100 μg OV...

journal_title：Oncology letters

authors： Cui L,Sun Y,Xu H,Xu H,Cong H,Liu J

更新日期：2013-10-01 00:00:00

abstract：:The basic helix-loop-helix transcription factor AP4 (TFAP4) gene serves an important function in the genesis and progression of tumors. However, few studies to date have defined the role of this gene in colorectal cancer (CRC). The aim of the present study was to assess the expression of TFAP4 in CRC and its impact on...

journal_title：Oncology letters

authors： Yang J,Ma JP,Xiao S,Zhang XH,Xu JB,Chen CQ,Cai SR,He YL

更新日期：2018-05-01 00:00:00

abstract：:The present study reviewed three patients with acute myeloid leukemia (AML) who had the specific genetic abnormality t(16;21)(p11;q22). To investigate the clinical and laboratory characteristics of AML with t(16;21)(p11;q22) translocation, the similarities and differences of clinical characteristics and laboratory exa...

journal_title：Oncology letters

authors： Zhang Z,Zou J,Li Y,Liu Z,Xu R,Tian W,Zhao Z,Sun H,Han J,Wang J,Zhang B,Ju Y

更新日期：2015-05-01 00:00:00

abstract：:Patients with longstanding ulcerative colitis have an increased risk of colorectal cancer. Mouse models for colitis-associated tumors are indispensable for the development of novel strategies for prevention and intervention, as well as an improved understanding of the mechanisms underlying tumor formation. The present...

journal_title：Oncology letters

authors： Yamauchi R,Kominato K,Mitsuyama K,Takedatsu H,Yoshioka S,Kuwaki K,Yamasaki H,Fukunaga S,Mori A,Akiba J,Tsuruta O,Torimura T

更新日期：2017-09-01 00:00:00

abstract：:A significant factor that affects the value of the Ki-67 proliferation index (IK) is the interpretation and implementation approach. This method is based on visual or automated methods to count tumor nuclei labeled with Ki-67 antigen, and is prone to errors. Detection of Ki-67 is a useful tool in breast cancer and con...

journal_title：Oncology letters

authors： Suciu C,Muresan A,Cornea R,Suciu O,Dema A,Raica M

更新日期：2014-01-01 00:00:00

abstract：:The role of mitogen-activated protein kinase (MAPK) signaling pathways in cell growth and differentiation has been well established. The present study aimed to investigate the anti-proliferative effect of stevioside on human colon cancer HT-29 cells. Additionally, the effect of stevioside on cell cycle arrest and MAPK...

journal_title：Oncology letters

authors： Ren HP,Yin XY,Yu HY,Xiao HF

更新日期：2017-04-01 00:00:00

abstract：:Trefoil factor 2 (TFF2) plays a protective role in gastric mucosa and may be involved in the progression of gastric cancer, but the detailed functions and underlying molecular mechanisms are not clear. The present study used a combination of clinical observations and molecular methods to investigate the correlation be...

journal_title：Oncology letters

authors： Jiang P,Yu G,Zhang Y,Xiang Y,Zhu Z,Feng W,Lee W,Zhang Y

更新日期：2014-05-01 00:00:00

abstract：:MicroRNAs (miRNAs/miRs) are identified to serve key functions in the progression of various tumors. miR-214 is aberrantly expressed in various types of cancer. In the present study, the function of miR-214 and its feasibility as a potential non-invasive biomarker for patients with prostate cancer (PCa) in a hyperplasi...

journal_title：Oncology letters

authors： Fang Y,Qiu J,Jiang ZB,Xu SR,Zhou ZH,He RL

更新日期：2019-01-01 00:00:00

abstract：:Current therapy for rheumatoid arthritis (RA) relies on global suppression of the immune response or specific blockade of inflammatory cytokines. However, it is unclear how immunosuppressants affect patients with cancer. Therefore, in the present study, the effect of three biological agents, tofacitinib, anti-mouse IL...

journal_title：Oncology letters

authors： Shimaoka H,Takeno S,Maki K,Sasaki T,Hasegawa S,Yamashita Y

更新日期：2017-09-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/ol.2017.6360.]. ...

journal_title：Oncology letters

authors： Liu X,Guo H,Wei Y,Cai C,Zhang B,Li J

更新日期：2021-02-01 00:00:00

abstract：:The downregulation of farnesoid X receptor (FXR; gene name, nuclear receptor subfamily 1 group h member 4), an enteric nuclear bile acid receptor, has been reported in colorectal carcinoma (CRC), and FXR expression has been inversely correlated with CRC stage and clinical outcome. FXR knockdown in chronic colitis mous...

journal_title：Oncology letters

authors： Mao J,Chen X,Wang C,Li W,Li J

更新日期：2020-07-01 00:00:00