Melanotic neuroectodermal tumor of infancy: A case report and review of the surgical treatment.

Abstract:

:Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, fast-growing, benign tumor originating from the neural crest. The tumor most often occurs during the first year of life. The predilection site of MNTI is the anterior maxilla, whereas lesions of the mandible are uncommon and account for only 6% of all cases. At present, the most common treatment for MNTI is surgical resection, however, tumor recurrence arises in 10-60% of cases. The optimal extent of surgical resection is a matter of debate; rapid growth and the possibilities of malignant transformation and metastasis indicate aggressive surgical resection. However, extensive resection may interfere with post-operative growth and development. The procedure should therefore preserve as much of the surrounding tissue as possible. The present case study examines a rare case of right-sided mandibular MNTI in a two-month-old female. The association between the tumor and the surrounding sclerotin, affected dental germ and the condition of the inferior alveolar nerve, were observed during the operative and post-operative periods. In addition, previous cases of MNTI were reviewed to evaluate the optimal scope of surgical resection.

journal_name

Oncol Lett

journal_title

Oncology letters

authors

Cui Y,Mao Z,Liao C

doi

10.3892/ol.2014.2665

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

29-34

issue

1

eissn

1792-1074

issn

1792-1082

pii

ol-09-01-0029

journal_volume

9

pub_type

杂志文章
  • Crizotinib induces apoptosis of lung cancer cells through JAK-STAT pathway.

    abstract::Effect of crizotinib on apoptosis of lung cancer cells was investigated. Human non-small cell lung adenocarcinoma H2228 cells were cultured in the presence of 0, 20, 40, 80, 160 and 320 nmol/l of crizotinib for 3 days, respectively. The inhibition rate of cell proliferation was measured by MTT assay, and half maximal ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.9387

    authors: Lu H,Wu S,Chen H,Huang Y,Qiu G,Liu L,Li Y

    更新日期:2018-11-01 00:00:00

  • Regulation of miR-155 affects the invasion and migration of gastric carcinoma cells by modulating the STAT3 signaling pathway.

    abstract::Studies investigating the effects of microRNA (miR)-155 on the behavior of tumor cells have concentrated primarily on proliferation and apoptosis. The aim of the present study was to investigate the effect of miR-155 inhibitor on the metastatic and invasive ability of gastric carcinoma cells and whether this effect is...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.9152

    authors: Wei H,Li Y,Ning Q,Suo ZM

    更新日期:2018-10-01 00:00:00

  • SIRT6 inhibits colorectal cancer stem cell proliferation by targeting CDC25A.

    abstract::Silent information regulator 6 (SIRT6) is broadly considered as a tumor suppressor due to its function in the suppression of oncogene expression. However, the role of SIRT6 in colorectal cancer stem cells (CSCs) remains uncharacterized. In the present study, it was demonstrated that SIRT6 expression was reduced in col...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.7989

    authors: Liu W,Wu M,Du H,Shi X,Zhang T,Li J

    更新日期:2018-04-01 00:00:00

  • Magnetic resonance imaging of the brain in survivors of childhood acute lymphoblastic leukemia.

    abstract::The issue of delayed neurological damage as a result of treatment is becoming increasingly important now that an increased number of children survive treatment for acute lymphoblastic leukemia (ALL). Following modification of the treatment protocols, severe symptomatic late effects are rare, and most adverse effects a...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2012.1072

    authors: Badr MA,Hassan TH,El-Gerby KM,Lamey ME

    更新日期:2013-02-01 00:00:00

  • Primary malignant gastrointestinal neuroectodermal tumor occurring in the ileum with intra-abdominal granulomatous nodules: A case report and review of the literature.

    abstract::Malignant gastrointestinal neuroectodermal tumors (GNETs) are rare aggressive malignant neoplasms that exclusively occur within the wall of the gastrointestinal tract. The GNET was first described as an 'osteoclast-rich tumor of the gastrointestinal tract with features resembling clear cell sarcoma (CCS) of soft parts...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10060

    authors: Huang GX,Chen QY,Zhong LL,Chen H,Zhang HP,Liu XF,Tang F

    更新日期:2019-04-01 00:00:00

  • The role of mast cell tryptases in cardiac myxoma: Histogenesis and development of a challenging tumor.

    abstract::A number of available studies have focused on the role of mastocytes and their angiogenic factors, such as tryptase expression, in cancer growth as a major research objective. Cardiac myxoma is a rare neoplasia and is the most common primary tumor of the heart. The cellular elements of cardiac myxoma have an endotheli...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2104

    authors: Donato G,Conforti F,Camastra C,Ammendola M,Donato A,Renzulli A

    更新日期:2014-07-01 00:00:00

  • Dysregulation of N6-methyladenosine regulators predicts poor patient survival in mantle cell lymphoma.

    abstract::N6-methyladenosine (m6A) is the most abundant eukaryote mRNA modification, modulated by regulators known as epigenetic writers, erasers and readers, which are known to serve crucial roles in mRNA metabolism. However, the role of m6A during B-cell development and B-cell tumorigenesis remains poorly understood. By analy...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10708

    authors: Zhang W,He X,Hu J,Yang P,Liu C,Wang J,An R,Zhen J,Pang M,Hu K,Ke X,Zhang X,Jing H

    更新日期:2019-10-01 00:00:00

  • Anaplastic thyroid carcinoma with diffuse thoracic skin metastasis: A case report.

    abstract::Anaplastic thyroid carcinoma is a significantly fatal endocrine neoplasm, with an average survival time of 4-12 months following diagnosis. The present study reports the case of a 57-year-old male patient who presented to the Bağcılar Training and Research Hospital (Istanbul, Turkey) due to swelling in the neck and di...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2036

    authors: Altinay S,Taş B,Ozen A,Süt PA

    更新日期:2014-06-01 00:00:00

  • Long non-coding RNA urothelial cancer associated 1 can regulate the migration and invasion of colorectal cancer cells (SW480) via myocardin-related transcription factor-A.

    abstract::Colorectal cancer (CRC) is the third leading cause of cancer-associated mortalities. Long non-coding RNAs (lncRNAs) have been identified as key regulators in the occurrence and development of CRC. The lncRNA urothelial cancer associated 1 (UCA1) has been demonstrated to promote the development of numerous different ty...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10737

    authors: Zhang L,Zheng C,Sun Z,Wang H,Wang F

    更新日期:2019-10-01 00:00:00

  • K9(C4H4FN2O2)2Nd(PW11O39)2·25H2O induces apoptosis in human lung cancer A549 cells.

    abstract::Lung cancer is the leading cause of cancer-associated mortality worldwide. The present study investigated the effects of K9(C4H4FN2O2)2Nd(PW11O39)2·25H2O (FNdPW), a chemically synthesized polyoxometalate that contains rare earth elements, on lung cancer growth, and explored the mechanism underlying its actions. The ef...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.5543

    authors: Xia RY,Zhang RR,Jiang Z,Sun YJ,Liu J,Chen FH

    更新日期:2017-03-01 00:00:00

  • Ophiopogonin D inhibits cell proliferation and induces apoptosis of human laryngocarcinoma through downregulation of cyclin B1 and MMP-9 and upregulation of p38-MAPK signaling.

    abstract::The pharmacological actions of Ophiopogonin D include resistance to cardiovascular and cerebrovascular diseases, anti-aging effects, improvement in learning deficit and dysmnesia, anti-tumor, anti-radiation and anti-inflammatory effects, immunoregulation, and the relief of cough and hepatopulmonary pathological lesion...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.9788

    authors: Yan Z,Liu G,Liang M,Xu Y

    更新日期:2019-02-01 00:00:00

  • Serum GP73 is complementary to AFP and GGT-II for the diagnosis of hepatocellular carcinoma.

    abstract::Golgi protein 73 (GP73) is a resident Golgi type II transmembrane protein that has been reported to markedly increase in chronic liver disease, particularly in hepatocellular carcinoma (HCC). However, it remains unclear as to whether serum GP73 represents a reliable serum marker for the diagnosis of HCC. The aim of th...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2013.1522

    authors: Hou SC,Xiao MB,Ni RZ,Ni WK,Jiang F,Li XY,Lu CH,Chen BY

    更新日期:2013-10-01 00:00:00

  • Metaplastic carcinoma of the breast with transformation from adenosquamous carcinoma to osteosarcomatoid and spindle cell morphology.

    abstract::Metaplastic carcinoma of the breast refers to a heterogenous group of mammary carcinomas that contain a mixture of various cell types, including squamous cells, spindle cells and/or a mesenchymal component, such as bone or cartilage. To the best of our knowledge, the clinical course of a tumour that has undergone a tr...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2013.1464

    authors: Chuthapisith S,Warnnissorn M,Amornpinyokiat N,Pradniwat K,Angsusinha T

    更新日期:2013-09-01 00:00:00

  • Long-term survival of a patient with scalp angiosarcoma and multiple metastases treated using combination therapy: A case report.

    abstract::Angiosarcoma is a rare and deadly malignancy originating from the vascular endothelial cells. Surgery is the most effective method to cure this disease, but for metastatic angiosarcoma, a chemotherapy-based treatment is the main therapeutic choice. However, there is currently no standard chemotherapy regimen. The curr...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.2919

    authors: Ye J,Li XF,Wang YD,Yuan Y

    更新日期:2015-04-01 00:00:00

  • Delta-like ligand 4: A predictor of poor prognosis in clear cell renal cell carcinoma.

    abstract::Delta-like ligand 4 (Dll4)-Notch signaling is important in tumor angiogenesis; however, the prognostic value of D114 detection in patients with clear cell renal cell carcinoma (CCRCC) remains unclear. The present study aimed to determine whether the presence of high Dll4 expression levels was correlated with poor prog...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2554

    authors: Wang W,Yu Y,Wang Y,Li X,Bao J,Wu G,Chang H,Shi T,Yue Z

    更新日期:2014-12-01 00:00:00

  • Medical termination of a partial hydatidiform mole and coexisting fetus during the second trimester: A case report.

    abstract::Partial hydatidiform mole and coexisting fetus (PHMCF) is a rare condition that presents a dilemma for physicians and the parents of the fetus, particularly when PHMCF is detected during the second trimester of pregnancy. The present study reports a case of PHMCF terminated by induction of labor via administration of ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.3743

    authors: Wang Y,Qian H,Wang J

    更新日期:2015-12-01 00:00:00

  • Downregulation of FHL1 protein in glioma inhibits tumor growth through PI3K/AKT signaling.

    abstract::Human four-and-a-half LIM domains protein 1 (FHL1) is a member of the FHL protein family, which serves an important role in multiple cellular events by interacting with transcription factors using its cysteine-rich zinc finger motifs. A previous study indicated that FHL1 was downregulated in several types of human can...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2020.11476

    authors: Li SZ,Hu YY,Zhao JL,Zang J,Fei Z,Han H,Qin HY

    更新日期:2020-06-01 00:00:00

  • Cytotoxic effect and tissue penetration of phenol for adjuvant treatment of giant cell tumours.

    abstract::Local adjuvant treatment of giant cell tumours (GCTs) of the bone with phenol has led to a significant reduction in recurrence rates. In the current study, the optimal phenol concentration and duration of intralesional exposure were evaluated. Specimens of GCTs were exposed to various concentrations of phenol solution...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2013.1244

    authors: Mittag F,Leichtle C,Kieckbusch I,Wolburg H,Rudert M,Kluba T,Leichtle U

    更新日期:2013-05-01 00:00:00

  • Special AT-rich sequence binding protein 1 regulates the multidrug resistance and invasion of human gastric cancer cells.

    abstract::Special AT-rich sequence binding protein 1 (SATB1) is a nuclear factor that functions as a global chromatin organizer to regulate gene expression. Recent studies have suggested an oncogenic role of SATB1 in breast cancer. However, the role of SATB1 in gastric cancer, especially in regulating the malignant phenotypes, ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2012.681

    authors: Sun F,Lu X,Li H,Peng Z,Wu K,Wang G,Tong Q

    更新日期:2012-07-01 00:00:00

  • Tanshinone IIA inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells via p53-cyclin B1/CDC2.

    abstract::Tanshinone IIA exhibits natural antioxidative and antineoplastic activity. However, to the best of our knowledge, the effects of tanshinone IIA on human nasopharyngeal carcinoma cells remains unknown. The present study aimed to investigate whether tanshinone IIA inhibits proliferation and induces apoptosis of human na...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10658

    authors: Liu B,Liu L,Zang A,Song Z,Yang H,Wang Z,Shang Y,Ma T,Zhang Y

    更新日期:2019-09-01 00:00:00

  • Effect of the LPA-mediated CXCL12-CXCR4 axis in the tumor proliferation, migration and invasion of ovarian cancer cell lines.

    abstract::Ovarian cancer is the most fatal gynecological cancer, with a 5-year survival rate of only 30%. Lysophosphatidic acid (LPA), which possesses growth factor-like functions, is a major regulatory factor in the peritoneal metastasis of ovarian cancer. LPA stimulates the expression of numerous genes that are associated wit...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.1926

    authors: Wang H,Liu W,Wei D,Hu K,Wu X,Yao Y

    更新日期:2014-05-01 00:00:00

  • Ex vivo hepatectomy and partial liver autotransplantation for hepatoid adenocarcinoma: A case report.

    abstract::We previously reported the case of a 56-year-old male who underwent surgical treatment for gastric hepatoid adenocarcinoma and splenic metastasis. The present study reports the case of the same patient who underwent successful ex vivo hepatectomy and partial liver autotransplantation. Computed tomography scans demonst...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.3041

    authors: Wang FQ,Lu Q,Yan J,Peng YY,Xie CR,Su YJ,Zhou JY,Wang BL,Zhao WX,Wang XM,Bie P,Yin ZY

    更新日期:2015-05-01 00:00:00

  • Therapy with transcutaneous administration of imiquimod combined with oral administration of sorafenib suppresses renal cell carcinoma growing in an orthotopic mouse model.

    abstract::Imiquimod is an imidazoquinoline immune response modifier that is used in antiviral and antiallergic creams. Combination therapy using transcutaneous imiquimod and oral sorafenib was previously demonstrated to reduce the tumor burden of renal cell carcinoma growing cutaneously in a mouse model. In the present study, a...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.6235

    authors: Karashima T,Udaka K,Niimura M,Suzuki K,Osakabe H,Shimamoto T,Fukata S,Inoue K,Kuroda N,Seiki M,Shuin T

    更新日期:2017-07-01 00:00:00

  • Corosolic acid inhibits the proliferation of osteosarcoma cells by inducing apoptosis.

    abstract::Corosolic acid (CRA), a pentacyclic triterpene isolated from medicinal herbs, has been reported to exhibit anticancer properties in several cancers. However, the anticancer activity of CRA in osteosarcoma cells is still unclear. In the present study, the inhibitory effect of CRA in osteosarcoma MG-63 cells was investi...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.5185

    authors: Jia Y,Yuan H,Shan S,Xu G,Yu J,Zhao C,Mou X

    更新日期:2016-11-01 00:00:00

  • Multiple regulatory mechanisms of hepatocyte growth factor expression in malignant cells with a short poly(dA) sequence in the HGF gene promoter.

    abstract::Hepatocyte growth factor (HGF) expression is a poor prognostic factor in various types of cancer. Expression levels of HGF have been reported to be regulated by shorter poly(dA) sequences in the promoter region. In the present study, the poly(dA) mononucleotide tract in various types of human cancer cell lines was exa...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2702

    authors: Sakai K,Takeda M,Okamoto I,Nakagawa K,Nishio K

    更新日期:2015-01-01 00:00:00

  • Genetics and epigenetics of melanoma.

    abstract::Cancer affects multiple organs in the body Malignant melanoma involves the invasion of skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of cutaneous malignant melanoma is on the increase worldwide and is a major concern in current research. The increase is associated with UV irradiation-i...

    journal_title:Oncology letters

    pub_type: 杂志文章,收录出版

    doi:10.3892/ol.2016.5093

    authors: Zhang XY,Zhang PY

    更新日期:2016-11-01 00:00:00

  • TRIM59 is a novel potential prognostic biomarker in patients with non-small cell lung cancer: A research based on bioinformatics analysis.

    abstract::Lung cancer is the leading cause of cancer-associated mortality worldwide and its prognosis is poor. Few effective biomarkers for non-small cell lung cancer (NSCLC) have been translated into the clinical practice aiming to assist in the treatment plan design and prognosis evaluation. The aim of the present study was t...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.6467

    authors: Hao L,Du B,Xi X

    更新日期:2017-08-01 00:00:00

  • Eps15 homology domain 1 promotes the evolution of papillary thyroid cancer by regulating endocytotic recycling of epidermal growth factor receptor.

    abstract::Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy, and it is often observed to overexpress epidermal growth factor receptor (EGFR). Previous research has indicated that EH domain-containing 1 (EHD1) is associated with EGFR-mediated endocytotic recycling in multiple tumor types. The objective...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.9200

    authors: Liu Y,Liang Y,Li M,Liu D,Tang J,Yang W,Tong D,Jin X

    更新日期:2018-10-01 00:00:00

  • Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats.

    abstract::Metabolic syndrome (Mets), including diabetes and hypertension, increases the risk of colorectal cancer via the induction of chronic inflammation, acceleration of oxidative stress, and activation of the renin-angiotensin system. The present study examined the possible inhibitory effects of captopril, an angiotensin-co...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2136

    authors: Kochi T,Shimizu M,Ohno T,Baba A,Sumi T,Kubota M,Shirakami Y,Tsurumi H,Tanaka T,Moriwaki H

    更新日期:2014-07-01 00:00:00

  • Intensity modulated radiation therapy to treat primary female mediastinal seminoma and massive pericardial effusion: A case report.

    abstract::Primary mediastinal seminoma is a rare extragonadal germ cell tumour that mainly occurs in males. The present study reports the case of a 27-year-old woman that presented with superior vena cava syndrome and a large mass in the mediastinum, which was diagnosed as primary female mediastinal seminoma. The patient receiv...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.5555

    authors: Cao J,Zhou Y,Zou F,Ma JA,Hu C

    更新日期:2017-03-01 00:00:00