Stochasticity of gene expression as a motor of epigenetics in bacteria: from individual to collective behaviors.

Abstract:

:Measuring gene expression at the single cell and single molecule level has recently made possible the quantitative measurement of stochasticity of gene expression. This enables identification of the probable sources and roles of noise. Gene expression noise can result in bacterial population heterogeneity, offering specific advantages for fitness and survival in various environments. This trait is therefore selected during the evolution of the species, and is consequently regulated by a specific genetic network architecture. Examples exist in stress-response mechanisms, as well as in infection and pathogenicity strategies, pointing to advantages for multicellularity of bacterial populations.

journal_name

Res Microbiol

journal_title

Research in microbiology

authors

Bury-Moné S,Sclavi B

doi

10.1016/j.resmic.2017.03.009

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

503-514

issue

6

eissn

0923-2508

issn

1769-7123

pii

S0923-2508(17)30069-4

journal_volume

168

pub_type

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