Abstract:
:5-Mycoloyl-beta-arabinofuranosyl-(1-->2)-5-mycoloyl-alpha-ar abinofuranosyl-(1-->1')-glycerol, an antigenic glycolipid from the Mycobacterium avium-intracellulare complex (MAC) was examined for its applicability to the serodiagnosis of MAC infection by ELISA. Serum IgM antibody titres against this glycolipid in healthy controls, pulmonary tuberculosis patients and sputum-MAC-culture-negative MAC patients were generally below the cut-off point (ELISA-negative), whereas most of the MAC-culture-positive MAC patient sera were ELISA-positive (93.5%) and their titres were often very high. Thus, high serum IgM titres against this glycolipid may be said to imply that the MAC disease is in an active phase.
journal_name
Res Microbioljournal_title
Research in microbiologyauthors
Honda I,Kawajiri K,Watanabe M,Toida I,Kawamata K,Minnikin DEdoi
10.1016/0923-2508(93)90048-7subject
Has Abstractpub_date
1993-03-01 00:00:00pages
229-35issue
3eissn
0923-2508issn
1769-7123pii
0923-2508(93)90048-7journal_volume
144pub_type
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