Suppression of immune response induction in Peyer's patch lymphoid cells from mice infected with mouse hepatitis virus.

abstract：:The cellular requirements for stimulating primed alloreactive T cells have been investigated. In vitro-primed secondary alloreactive cells, long-term lines, and Ly 1+2- noncytolytic clones which reacted with allo-H-2K, D, or Mls (M locus) antigens were tested. The data indicated that a specialized antigen-presenting c...

journal_title：Cellular immunology

authors： Sunshine GH,Mitchell TJ,Czitrom AA,Edwards S,Glasebrook AL,Kelso A,MacDonald HR

更新日期：1985-03-01 00:00:00

abstract：:Adenomatous polyposis coli (APC) functions are involved in the heterotypic interactions occurring between intestinal epithelial cells (IECs) and intra-epithelial lymphocytes (IELs). These interactions may be of interest in cancer prevention, since recent data provide evidence for lymphocyte mediated immunosurveillance...

journal_title：Cellular immunology

authors： Forest V,Pierre F,Bassonga E,Meflah K,Olivier C,Menanteau J

更新日期：2003-05-01 00:00:00

abstract：:The induction of ornithine decarboxylase (ODC) activity in lymphocytes is associated with activation and the initiation of cellular proliferation. ODC is also an essential component in tumor promotion. Phorbol myristic acetate (PMA) is a mitogen for lymphocytes, but can also promote tumor formation. Tumor promotion is...

journal_title：Cellular immunology

authors： Fidelus RK

更新日期：1988-04-15 00:00:00

abstract：:The internalization of surface immunoglobulin (Ig) by B lymphocytes is the first step in the antigen-presenting function performed by these cells. Mature B cells coexpress on their surface IgM and IgD. At this time, there is controversy over whether these two isotypes serve different functions in the antigen-presentin...

journal_title：Cellular immunology

authors： Guarini L,Weber DA,Pernis B

更新日期：1989-10-15 00:00:00

abstract：:Mouse thyroglobulin (MTg)-sensitized spleen cells activated in vitro with MTg induced experimental autoimmune thyroiditis (EAT) in which the thyroid infiltrate consists primarily of mononuclear cells (MNC) (lymphocytic EAT). MTg-sensitized spleen cells cultured with MTg together with anti-IL2R antibody induce a granul...

journal_title：Cellular immunology

authors： McMurray RW,Hoffman RW,Tang H,Braley-Mullen H

更新日期：1996-08-25 00:00:00

abstract：:We investigated the influence of Panagen DNA preparations on laboratory animals and IFN-induced human dendritic cells, as well as analyzed the data from a phase II clinical trial in the therapy of breast cancer. It was shown that this treatment resulted in increased number of CD8+/perforin+ T cells in peripheral lymph...

journal_title：Cellular immunology

authors： Alyamkina EA,Leplina OY,Ostanin AA,Chernykh ER,Nikolin VP,Popova NA,Proskurina AS,Gvozdeva TS,Dolgova EV,Orishchenko KE,Rogachev VA,Sidorov SV,Varaksin NA,Ryabicheva TG,Bogachev SS,Shurdov MA

更新日期：2012-03-01 00:00:00

abstract：:The complement receptor 2 (CR2; CD21), a 145,000 MW glycoprotein, has been useful as a marker of B lymphocyte maturation. It is expressed on the 1:13 monoclonal, EBV-transformed, B cell line which produces TNP-specific IgM-kappa and displays an in vitro capacity for differentiation. The line expresses the CD20+CD21+ p...

journal_title：Cellular immunology

authors： Pillemer SR,Tsokos GC,Barbieri SA,Balow JE,Golding B

更新日期：1990-02-01 00:00:00

abstract：:B-1a cells represent a distinct B cell population with unique phenotype, self-renewing capacity and restricted Igμ repertoire. They primarily locate in body cavity and also exist in spleen. The different subpopulations of B-1a cells are heavily affected by local environment. Our previous studies revealed that MARVEL-d...

journal_title：Cellular immunology

authors： Liu Z,Liu Y,Li T,Wang P,Mo X,Lv P,Ma D,Han W

更新日期：2020-06-01 00:00:00

abstract：:Nickel (Ni) can cause delayed-type hypersensitivity reactions, which are thought to be mediated by the accumulation of T cells into inflamed skin. Accumulated T cells at the developmental stages in metal allergy are poorly characterized because a suitable animal model has not been established. To investigate the accum...

journal_title：Cellular immunology

authors： Eguchi T,Kumagai K,Kobayashi H,Shigematsu H,Kitaura K,Suzuki S,Horikawa T,Hamada Y,Ogasawara K,Suzuki R

更新日期：2013-07-01 00:00:00

abstract：:Mucus production by goblet cells in the gastrointestinal tract following Salmonella typhimurium infection using a ligated ileal loop model in mice was investigated. Assessment of the morphology of the loop tissue after Salmonella challenge revealed generalized tissue inflammation, characterized by edema and an inflamm...

journal_title：Cellular immunology

authors： Arnold JW,Klimpel GR,Niesel DW

更新日期：1993-10-15 00:00:00

abstract：:Stimulation via the CD3/TCR molecular complex induces proliferation of resting T cells, but triggers programmed cell death (apoptosis) in immature thymocytes and preactivated mature T cells. Activation-induced cell death (AICD) triggered by anti-CD3/TCR mAb or by staphylococcus enterotoxin superantigen is associated w...

journal_title：Cellular immunology

authors： Pohl T,Pechhold K,Oberg HH,Wilbert OM,Kabelitz D

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Piper nigrum L. (Piperaceae) is commonly used as a spice and traditional medicine in many countries. It has been reported to have anti-oxidant, anti-bacterial, anti-tumor, anti-mutagenic, anti-diabetic, and anti-inflammatory properties. However, the protective role of P. nigrum on epithelial function of uppe...

journal_title：Cellular immunology

authors： Bui TT,Fan Y,Piao CH,Nguyen TV,Shin DU,Jung SY,Hyeon E,Song CH,Lee SY,Shin HS,Chai OH

更新日期：2020-05-01 00:00:00

abstract：:This investigation shows that Epstein-Barr virus (EBV)-activated human B cells from marrow transplant recipients can produce in vitro IgG anti-tetanus toxoid antibody (anti-TT) without booster immunizations with tetanus toxoid (TT). Purified B cells (E-rosette negative) from 8 normal subjects, 6 healthy long-term marr...

journal_title：Cellular immunology

authors： Jin NR,Lum LG

更新日期：1986-08-01 00:00:00

abstract：:A majority (42/62) of TCR2+ interleukin 2-dependent human T lymphocyte clones was found concordantly to express not only the CD28 co-receptor structure at the cell surface but also its ligand B7. Interactions between CD28 and B7 can have important consequences for T cell activation, particularly in providing "signal 2...

journal_title：Cellular immunology

authors： Friccius H,Siegels-Hübenthal P,Rehbein A,Schlotz E,Pawelec G

更新日期：1993-10-15 00:00:00

abstract：:Activated macrophages are known to release a variety of immunoregulatory substances including the low-molecular-weight substances hydrogen peroxide and lactate. We report here that lactate but not hydrogen peroxide is capable of supporting a substantial production of T-cell growth factor (TCGF) in cultures of accessor...

journal_title：Cellular immunology

authors： Roth S,Dröge W

更新日期：1987-09-01 00:00:00

abstract：:Although it is known that IGF-1 increases T lymphocyte proliferation, the regulation of its receptor expression during the process has not been defined. Consequently the regulation of IGF-1R expression by IGF-1 and the activation events in human blood T lymphocytes and the Jurkat T cell line were now investigated. IGF...

journal_title：Cellular immunology

authors： Schillaci R,Brocardo MG,Galeano A,Roldán A

更新日期：1998-02-01 00:00:00

abstract：:Dendritic cells initiate the immune response by presenting antigen in the context of varying levels of costimulation. The maturation state of the dendritic cell determines the quantity and quality (Th1, Th2) of the subsequent T cell response. Members of the NF-kappaB family of transcription factors have previously bee...

journal_title：Cellular immunology

authors： Boffa DJ,Feng B,Sharma V,Dematteo R,Miller G,Suthanthiran M,Nunez R,Liou HC

更新日期：2003-04-01 00:00:00

abstract：:Macrophages in varying states of activation differ in their ability to perform antibody-dependent cellular cytotoxicity (ADCC) and antibody-independent macrophage-mediated tumor cytotoxicity (MTC). To define further the activation requirements for macrophages to perform various cytolytic functions, we stimulated pepto...

journal_title：Cellular immunology

authors： Fan S,Fehr HG,Adams D

更新日期：1991-06-01 00:00:00

abstract：:Vitamin D regulates homeostasis, anti-microbial response, and inflammation. The vitamin D receptors are expressed in the macrophages and other immune cells, regulating the transcription of many different genes, including those coding the anti-microbial peptides. One of the most severe complications of the SARS-CoV-2 i...

journal_title：Cellular immunology

authors： Kloc M,Ghobrial RM,Lipińska-Opałka A,Wawrzyniak A,Zdanowski R,Kalicki B,Kubiak JZ

更新日期：2021-02-01 00:00:00

abstract：:Twenty-seven different CD45 monoclonal antibodies (mAb) were assessed for their ability to block cytotoxicity of alloreactive CD4+ MHC class II-specific or CD8+ class I-specific human T cell clones (n = 3 and 5, respectively). Twelve of 27 blocked the former but only 1/27 the latter, although all 27 significantly inhi...

journal_title：Cellular immunology

authors： Pawelec G,Bühring HJ,Müller C

更新日期：1990-05-01 00:00:00

abstract：:We have previously used human Epstein Barr virus (EBV)-transformed B lymphoblastoid cell lines for the identification and purification of a novel cytokine, natural killer cell stimulatory factor (NKSF/IL-12), that has pleiotropic effects on human lymphocytes. B cell lines are also routinely employed as feeder cells fo...

journal_title：Cellular immunology

authors： Valiante NM,Rengaraju M,Trinchieri G

更新日期：1992-11-01 00:00:00

abstract：:Chronic relapsing experimental allergic encephalomyelitis (CR-EAE) can be adoptively transferred using myelin basic protein (BP)-specific helper T cell lines, and suppressor cells may be important in recovery from EAE. In order to generate suppressor cells, spleen cells obtained from BP-complete Freund's adjuvant (CFA...

journal_title：Cellular immunology

authors： Whitham RH,Vandenbark AA,Bourdette DN,Chou YK,Offner H

更新日期：1990-04-01 00:00:00

abstract：:In this study, skin-infiltrating cells were prepared from guinea pig delayed-type hypersensitivity reaction sites, and their phenotypic properties and cytokine production were examined. Our cell preparations contained around 45% nonspecific esterase-positive cells and a few skin-derived cells. Skin-infiltrating cells ...

journal_title：Cellular immunology

authors： Higashi N,Yoshizuka N,Kobayashi Y

更新日期：1995-08-01 00:00:00

abstract：:Prevention of ultraviolet radiation- or chemical carcinogen-induced morphologic transformation and inhibition of tumor-producing transformed cell growth by lymphotoxin and by normal spleen leukocytes were quantitatively compared to define the antineoplastic activity spectra of these natural immune mediators. When Syri...

journal_title：Cellular immunology

authors： Evans CH,Heinbaugh JA,DiPaolo JA

更新日期：1983-03-01 00:00:00

abstract：:The antigenic phenotype of individual PHA-induced T lymphocyte colonies was studied with a direct immunofluorescence technique using fluorescein-labeled anti-Leu-2a and anti-Leu-3a antibodies. Of the colonies grown from mononuclear peripheral blood cells 85% were Leu-3a+ (inducer/helper phenotype), 12% were Leu-2a+ (s...

journal_title：Cellular immunology

authors： Claësson MH,Petersen J,Sønderstrup-Hansen G,Röpke C,Sørensen T

更新日期：1983-10-15 00:00:00

abstract：:Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curable strategy for the treatment of hematological malignancies and nonmalignant diseases. However, graft-versus-host disease (GVHD) and relapse are still two major causes of morbidity and mortality after allo-HSCT, and both restrict the improvement ...

journal_title：Cellular immunology

authors： Gu G,Yang JZ,Zhang JQ,Sun LX

更新日期：2019-12-01 00:00:00

abstract：:Murine peritoneal macrophages (M phi), activated in vivo or in vitro, remarkably inhibited the uptake of thymidine by a lens epithelial cell line, while resident M phi, or M phi induced by thioglycollate, exhibited much lower or no cytostatic capacity. The target cells were partially protected from the cytostatic acti...

journal_title：Cellular immunology

authors： Mochizuki M,Zigler JS Jr,Russell P,Gery I

更新日期：1984-01-01 00:00:00

abstract：:The clinical outcome of Leishmania pathogenesis ranges from active skin lesions to fatal visceral dissemination and severely impaired T cell immunity. It is well established that a strong Th1 immune response is protective against cutaneous forms of the disease, however a mixed Th1/Th2 response is most commonly observe...

journal_title：Cellular immunology

authors： Banerjee A,Bhattacharya P,Joshi AB,Ismail N,Dey R,Nakhasi HL

更新日期：2016-11-01 00:00:00

abstract：:The mechanism by which purinergic agonists modulate murine T-lymphocyte activation and proliferation was investigated. Adenosine and other compounds such as ATP and 2-chloroadenosine (ClAdo) were found to block T-cell mitogenesis induced by concanavalin A (Con A) in a dose-dependent fashion. The nonmetabolizable adeno...

journal_title：Cellular immunology

authors： DosReis GA,Nóbrega AF,de Carvalho RP

更新日期：1986-08-01 00:00:00

abstract：:We investigated the effects of prostaglandin E2 and IL-4 on the acquisition of cytokine-producing ability by naive CD4(+) T cells in human umbilical cord blood. The presence of PGE2 or IL-4 at primary stimulation inhibited the production of IFN-gamma at secondary stimulation, and the combination of these stimuli resul...

journal_title：Cellular immunology

authors： Abe N,Katamura K,Shintaku N,Fukui T,Kiyomasu T,Iio J,Ueno H,Tai G,Mayumi M,Furusho K

更新日期：1997-10-10 00:00:00