Abstract：
:Balb/c mice were infected with influenza virus PR8 (H1N1) by the intranasal route. At various subsequent times, brain samples were examined for their content of catecholamine and indoleamine metabolites, and plasma corticosterone was measured. Virus infection was associated with a progressive loss of body and thymus weights, and an increase in plasma corticosterone. Spleen weight initially increased then decreased. There were also increases in the cerebral content of free tryptophan throughout the brain, and of MHPG, a major catabolite of norepinephrine, especially prominent in the hypothalamus. Thus influenza virus can be regarded as a stressor because, like behavioral stressors, it activates the hypothalamic-pituitary-adrenal axis, and increases cerebral concentrations of tryptophan and norepinephrine catabolites. These changes resemble those observed following administration of sheep red blood cells and Newcastle disease virus, noninfectious activators of the immune system, suggesting that noradrenergic and HPA activation are common concomitants of antigenic stimulation. The mediator of these effects may be interleukin-1 released by activated macrophages. It should be noted that animals infected with viruses can be expected to exhibit stress-like endocrine and neurochemical changes.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Dunn AJ,Powell ML,Meitin C,Small PA Jrdoi
10.1016/0031-9384(89)90078-4subject
Has Abstractpub_date
1989-03-01 00:00:00pages
591-4issue
3eissn
0031-9384issn
1873-507Xpii
0031-9384(89)90078-4journal_volume
45pub_type
杂志文章abstract：:There is considerable evidence suggesting that endogenous opioid peptides (EOP) might play a role in the defensive response to stressful stimuli. The stress associated with receipt of aggression from a female conspecific and physical restraint for collection of serial blood samples (at 10-min intervals) resulted in a ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90241-2
更新日期：1989-05-01 00:00:00
abstract：:Sexual behavior in female rats is dependent on gonadal steroids. In ovariectomized rats, progesterone treatment typically exerts a biphasic effect on copulatory behavior induced by prior treatment with estradiol. Thus, there is an initial augmentation of the facilitative effect of estradiol occurring 4-10 h after prog...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90378-f
更新日期：1992-11-01 00:00:00
abstract：:Calorie restriction (CR) has been promoted to increase longevity. Previous studies have indicated that CR can negatively affect mood and therefore the effect of CR on mood and quality of life (QOL) becomes crucial when considering the feasibility of CR in humans. We conducted a three month clinical trial on CR (reduct...
journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.physbeh.2011.07.007
更新日期：2011-10-24 00:00:00
abstract：:Gustatory avoidance studies normally focus on the diminished occurrence of a consummatory behavior as the primary dependent variable. Several reports have described behaviors which accompany this gustatory avoidance response but no attempt has been made to automate collection of such data. In the following studies lit...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90213-6
更新日期：1985-03-01 00:00:00
abstract：:The central effect of oxytocin (OT) on the aggressive behavior of lactating rats was studied. Female rats are more aggressive than nonlactating resident females, vigorously attacking conspecific intruder male or females. This behavior is considered important for pup protection against infanticide. The present work aim...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.05.002
更新日期：2005-06-30 00:00:00
abstract：:Recent studies suggest that the decreased drinking response to hypertonic saline produced by bilateral subdiaphragmatic vagotomy (VGX) is a function of the route of saline administration and the length of postoperative recovery. We determined the effects of VGX on drinking during the two hours after intraperitoneal an...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90086-5
更新日期：1982-02-01 00:00:00
abstract：:The effect of epileptogenic lesion of amygdala on spatial working memory was examined in rats after unilateral (U, n = 9) or bilateral (B, n = 8) injection of 1 or 0.5 mu of 0.2% kainate into the amygdaloid complex. Another group of unilaterally lesioned rats (T, n = 9) received 8 days after kainate injection grafts o...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90124-8
更新日期：1989-02-01 00:00:00
abstract：:We examined the physiological and psychological status of men and women who spent the summer (n=100) and/or winter (n=85) seasons in Antarctica at McMurdo (latitude 78.48 S, elevation 12 m) and South Pole (latitude 90 S, elevation 3880 m) stations to determine whether there were any significant differences by severity...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.06.008
更新日期：2007-12-05 00:00:00
abstract：PURPOSE:The aim of this observational study was to identify biomechanical differences, as measured by pharyngeal manometric pressure patterns, between discrete and continuous water swallowing, as well as volitionally initiated and reflexive swallowing. METHODS:Using pharyngeal manometry, swallowing-related pressures f...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.12.029
更新日期：2015-03-01 00:00:00
abstract：:The effect of breakfast and breakfast omission on daily food intake in normal and overweight participants was investigated. 37 participants were recruited for this experimental study and assigned to one of four groups on the basis of their body mass index (BMI) (normal weight BMI <25 kg/m(2) or overweight/obese BMI >2...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.05.015
更新日期：2014-06-22 00:00:00
abstract：:Oxytocin treatment in rats induces long-lasting antistress and growth promoting effects. This study investigated whether prolyl-leucyl-glycinamide (PLG) (the c-terminal tripeptide of oxytocin) or tocinoic acid (the ring structure of oxytocin) could induce some of these effects in male rats. For this purpose, PLG (2 or...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.08.034
更新日期：2004-12-15 00:00:00
abstract：:Early overnutrition disrupts leptin sensitivity and the development of hypothalamic pathways involved in the regulation of metabolism and feeding behavior. While previous studies have largely focused on the development of neuronal projections, few studies have examined the impact of early nutrition on hypothalamic syn...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.04.002
更新日期：2019-07-01 00:00:00
abstract：:The aim of the present study was to test the hypothesis that vesicular glutamate transporter 3 (VGluT3) deficiency is associated with cognitive impairments. Male VGluT3 knockout (KO) and wild type (WT) mice were exposed to a behavioral test battery covering paradigms based on spontaneous exploratory behavior and reinf...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.112688
更新日期：2019-12-01 00:00:00
abstract：:Male rats which ingest feces of lactating females produce anal excreta which is attractive to pups. This excreta is as attractive as that of lactating females and more attractive than the excreta of males eating a diet of lab chow only. Anal excreta of males which consume feces of lactating females is more attractive ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90098-7
更新日期：1983-07-01 00:00:00
abstract：:This study compared subjective effort perception with objective physiological measures during high-intensive intermittent exercise performed in normoxia, moderate hypoxia (FiO2: 16.5%) and severe hypoxia (FiO2: 13.5%). Sixteen physically active subjects performed an equal training session on three different days. Trai...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.04.035
更新日期：2016-09-01 00:00:00
abstract：:Difficulty in initiating sleep is an important problem because it is associated with an increased incidence of depression, diabetes, myocardial infarction, and higher all-cause mortality. Although experimental studies in controlled settings have shown that warm skin temperature of the extremities (feet and hands) befo...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.05.022
更新日期：2015-10-01 00:00:00
abstract：:The pituitary-adrenal response of mother and infant squirrel monkeys was assessed under basal conditions and after 5, 10, or 20 min of separation followed by 30 min of reunion. All separation conditions produced equal increments of cortisol (approximately 50%) in both mothers and infants. These increments were lower t...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90029-0
更新日期：1985-06-01 00:00:00
abstract：:The aim of the study was to examine the Spielberger's hypothesis, according to which changes in state-anxiety level would correspond exactly to adverse changes in mood states. We analyzed the correlation coefficients between state-anxiety and low moods, and further investigated whether these correlation coefficients i...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00575-3
更新日期：2001-11-01 00:00:00
abstract：:Scopolamine induced blockade of play fighting in juvenile rats and the rapid induction of behavioral tolerance to an initially effective dosage suggested a rebound in social play following chronic scopolamine exposure. Juvenile rats received daily intraperitoneal scopolamine or saline injections for one week. Play sol...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90132-x
更新日期：1984-02-01 00:00:00
abstract：:Recent research suggests that gratitude is associated with better cardiovascular health. Here, we investigated whether trait and/or state gratitude was associated with cardiovascular responses to acute stress. Eighty-six young adults completed measures of gratitude and had their cardiovascular responses monitored thro...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.112896
更新日期：2020-07-01 00:00:00
abstract：:A binge drinking pattern of alcohol consumption has been shown to have an impact on brain structures that continue to develop into late adolescence. These same brain structures have been implicated in processing self-movement cues. The current study applies an array of existing and novel kinematic analysis techniques ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.04.027
更新日期：2016-07-01 00:00:00
abstract：:Eight obese patients (exceeding ideal body weight by 50% or more) with no endocrinological or metabolic disorders and 8 healthy, age-matched, normal-weight volunteers were submitted to an overnight short dexamethasone (DXM) suppression test and to a psychological assessment through various psychometric scales. Plasma ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90456-7
更新日期：1986-01-01 00:00:00
abstract：:Sjogren's Syndrome (SS) patients have impaired salivary gland function and an elevated frequency of oral complaints. The taste complaints are thought to be due to sensory deficits that arise in the absence of sufficient saliva to maintain taste receptors. We assessed the subjective complaints, salivary production and ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)00211-m
更新日期：1995-01-01 00:00:00
abstract：:The ontogenetic development of postingestive inhibitory control of ingestion by an oil preload was examined in preweaning rats. Gastric preloads (5% b.wt) of water, mineral oil or corn oil were administered 5 min before a 30-min intake test in which pups licked milk from the floor of a test chamber. Preloads of corn o...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00256-4
更新日期：1997-10-01 00:00:00
abstract：:Chronic exposure to a diet rich in fats changes the gastrointestinal milieu and alters responses to several signals involved in the control of food intake. Oleoylethanolamide (OEA) is a gut-derived satiety signal released from enterocytes upon the ingestion of dietary fats. The anorexigenic effect of OEA, which requir...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.04.039
更新日期：2014-09-01 00:00:00
abstract：:The zebrafish has become increasingly utilized in behavioral neuroscience, psychopharmacology, and behavior genetics research. However, little attention has been paid to the potential effects of environmental conditions fish are exposed to before and during behavioral testing. One such important factor is temperature,...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113169
更新日期：2020-12-01 00:00:00
abstract：:The deterioration of homeostasis between oxidant/antioxidant species may represent an important mechanism linking psychological stress to cardiovascular risk despite the many sex differences in stress responsiveness. The goal of the present study was to investigate the influence of chronic mild stress (CMS), a widely ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.05.011
更新日期：2009-08-04 00:00:00
abstract：:We recorded evoked potentials during performance of a reaction-time task, in which rats had to release a lever quickly in response to either a visual or an auditory stimulus for a food reward. We found two distinct peaks in their cortical evoked potentials. The first peak appeared at a fixed time after the stimulus, i...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90145-x
更新日期：1988-01-01 00:00:00
abstract：:Single unit activities from the olfactory bulb were recorded during sniffing in unanesthetized rats. Spectral analyses by the Walsh transform were applied to the spike trains of units. In addition, inter-spike intervals (ISIs) were measured to estimate post-spike excitability and serial correlations. The modulation of...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00137-1
更新日期：1998-07-01 00:00:00
abstract：:Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from intestinal L-cells in response to food entering into the gastrointestinal tract. GLP-1-based pharmaceuticals improve blood glucose regulation and reduce feeding. Specific macronutrients, when ingested, may trigger GLP-1 secretion and enhance the effe...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.04.017
更新日期：2017-08-01 00:00:00
