Abstract：
:Single unit activities from the olfactory bulb were recorded during sniffing in unanesthetized rats. Spectral analyses by the Walsh transform were applied to the spike trains of units. In addition, inter-spike intervals (ISIs) were measured to estimate post-spike excitability and serial correlations. The modulation of firing due to respiration cycles was observed only in four units (10%). Thirty-three units (82.5%) displayed low-frequency fluctuations such as 1/f noise in spike density. Their spectral density for the low-frequency range was inversely proportional to the frequency, to the power of 0.08-0.55. These units also showed "hyper-recovery" in post-spike excitability. In addition, the first-order serial correlation of ISIs was significantly positive in 36 units (90%). The degree of 1/f fluctuation was significantly correlated with the amplitude of "hyper-recovery" in post-spike excitability and with the serial correlation coefficient. To test the hypothesis that the self-facilitation of a neuron causes 1/f fluctuations in its spike trains, simulations of single neuron activity with self-facilitation were performed using an integrate-and-fire neuron model, and its spike trains were analyzed. The model neuron with self-facilitation mimicked the characteristics observed in olfactory bulb neurons such as 1/f fluctuations in spike density, positive correlations between successive ISIs and "hyper-recovery" in post-spike excitability. These results suggest that olfactory bulb neurons have a mechanism for self-facilitation causing 1/f fluctuations in spike density.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Ogawa Ydoi
10.1016/s0031-9384(98)00137-1subject
Has Abstractpub_date
1998-07-01 00:00:00pages
755-64issue
5eissn
0031-9384issn
1873-507Xpii
S0031938498001371journal_volume
64pub_type
杂志文章abstract：BACKGROUND:Hydrogen sulfide (H2S) is the third gasotransmitter recently discovered after nitric oxide (NO) and carbon monoxide. Both NO and H2S are involved in multiple physiological functions. Whereas NO has been shown to vary with psychological stress, the influence of stress on H2S and the relationship between H2S a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.05.023
更新日期：2017-10-01 00:00:00
abstract：:This review article discusses the well-established role of the dorsomedial hypothalamic nucleus (DMN) in feeding, drinking and body weight (BW) regulation. DMN lesions (L) in both weanling and mature rats of both sexes produce hypophagia, hypodipsia and reduced ponderal and linear growth in the presence of normal body...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/s0031-9384(02)00756-4
更新日期：2002-07-01 00:00:00
abstract：:The functional effects of chronic administration of 60 mg kg-1 chloroquine or quinacrine given as daily intraperitoneal injections for 84 days on normal and denervated expansor secundariorum muscles, a smooth muscle from the wing of chicks wholly innervated by noradrenergic nerves, have been investigated. Administrati...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90121-u
更新日期：1993-08-01 00:00:00
abstract：:The effect of exercise on central nervous system function was investigated in relation to the mechanism of calcium-calmodulin-dependent dopamine synthesis in the brain. It is shown here through animal experiments that exercise leads to an increase in the calcium level in the brain. This in turn enhances brain dopamine...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(96)00011-x
更新日期：1996-07-01 00:00:00
abstract：:Enkephalins facilitate female reproductive behavior. Within the limbic system and hypothalamus, estrogen induced the expression of preproenkephalin (PPE) mRNA. Estrogen injection caused a biphasic increase in the PPE mRNA levels within the ventromedial hypothalamic nucleus and posterodorsal medial amygdala. The first ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00261-9
更新日期：2000-06-01 00:00:00
abstract：:Rats secrete saliva in response to heat. In the present study, details of thermal salivation were investigated using the FOK rat in comparison with Sprague-Dawley (SD), Donryu, and ACI rats. The FOK rat is a strain inbred for genotypic heat adaptation and endures heat for long periods. Conscious rats of all four strai...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00541-6
更新日期：1998-03-01 00:00:00
abstract：:Women in the reproductive age are more vulnerable to develop affective disorders than men. This difference may attribute to anatomical differences, hormonal influences and environmental factors such as stress. However, the higher prevalence in women normalizes once menopause is established, suggesting that ovarian hor...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
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更新日期：2009-05-25 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90008-7
更新日期：1982-08-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90080-6
更新日期：1986-01-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.02.017
更新日期：2019-07-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90040-6
更新日期：1988-01-01 00:00:00
abstract：:Insulin is mainly known for its peripheral effects on the metabolism of glucose, fats, and proteins. However, insulin also exerts important actions within the brain, and functions as a neuropeptide. The brain can thus be regarded as both an insulin-sensitive and a glucose-sensitive organ. Its neuroanatomical basis is ...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2004.07.022
更新日期：2004-10-30 00:00:00
abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by a progressive loss of cognitive function. Despite considerable progress, a complete description of the molecular pathology of this disease has yet to be elucidated. In this respect, the need for an animal model that develops some or all aspects...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/s0031-9384(01)00524-8
更新日期：2001-08-01 00:00:00
abstract：:Diet is an environmental factor with significant potential to affect the brain and behavior in both positive and negative ways. Work in animals is necessary to understand this relationship and how it may apply to mental health in humans. One area which has been investigated extensively is whether diet, specifically a ...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2020.112965
更新日期：2020-09-01 00:00:00
abstract：:Isometric handgrip is commonly used in stress research because the task reliably increases sympathetic arousal. Various handgrip protocols have been used; they vary in handgrip strength, duration of grip, and the number of cycles of handgrip and rest. However, most protocols require the calibration of a maximum volunt...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.01.031
更新日期：2015-04-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.03.001
更新日期：2017-07-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00167-4
更新日期：1997-10-01 00:00:00
abstract：:There is a wide body of literature to suggest that sexual experience may influence androgen secretion in various species, in turn, androgens may also influence anxiety. We hypothesized that sexual experience may alter anxiety behavior and secretion of endogenous androgens. Experiment 1: anxiety behavior of rats with a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.04.018
更新日期：2007-10-22 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.02.003
更新日期：2011-06-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)02231-7
更新日期：1996-06-01 00:00:00
abstract：AIMS:Ghrelin is one of the most potent orexigens known to date. While the prevailing view is that ghrelin participates in the homeostatic control of feeding, the question arose as to whether consummatory responses evoked by this compound could be related to search for reward. We therefore attempted to delineate the inv...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2010.05.017
更新日期：2010-09-01 00:00:00
abstract：:Puberty is a critical period for neurodevelopment of schizophrenia. In the present study, we investigated the effects of peri-pubertal social isolation on psychotic behaviors in rats and its relationship to dopamine expression. Wistar male rats were randomly divided into pubertal isolation (ISO; isolate housing, 38-51...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.05.021
更新日期：2009-09-07 00:00:00
abstract：:Amino acid deficiency was modeled by feeding rats a diet deficient in the essential L-amino acid, L-lysine (L-lys). There is a rapid anorectic response to such a diet, and a strong preference for L-lys develops during the deficiency. While the brain appears to trigger this preference, the peripheral pathways that info...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00426-7
更新日期：2001-04-01 00:00:00
abstract：:Body temperature (Tb) was monitored telemetrically in adult deer mice kept in an environmental chamber at low ambient temperature (Ta = 15 degrees C). Mice were challenged with various doses of 2-deoxy-D-glucose (2DG, a glycolysis inhibitor) or mercaptoacetate (MA, a fatty acid oxidation inhibitor) or a combination of...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(96)00495-7
更新日期：1997-04-01 00:00:00
abstract：:Four groups of female golden hamsters were exposed to short photoperiods (SP, LD 10:14) for 4, 14, 20, or 27 weeks and tested for physiological markers (uterine weight and estrous cycles) and behavioral (lordosis, approach and aggressive behaviors) measures while in contact with a stud male. After behavioral testing, ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90078-3
更新日期：1991-08-01 00:00:00
abstract：:The ability to utilize oxygen has been shown to affect a wide variety of physiological factors often considered beneficial for survival. As the ability to learn can be seen as one of the core factors of survival in mammals, we studied whether selective breeding for endurance running, an indication of aerobic capacity,...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.01.011
更新日期：2012-05-15 00:00:00
abstract：:Many lateral hypothalamic electrodes that support self-stimulation also elicit feeding. Refractory period and conduction velocity estimates for the axons supporting these behaviors appear identical, suggesting that these behaviors may be elicited by stimulation of a common directly activated substrate. However, it is ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90007-q
更新日期：1990-05-01 00:00:00
abstract：:The role of protein, carbohydrate and fat ingestion on self-rated mood and subsequent food intake was investigated using self-reports of spontaneous food intake. Eight male and 30 female undergraduate students were instructed to list everything they ate, when they ate it, and their mood at the time of ingestion. They ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90154-5
更新日期：1987-01-01 00:00:00
abstract：:Earlier research has demonstrated that opioid involvement in drinking is primarily mediated centrally [8,10]. Drinking is attenuated by the centrally and peripherally active opioid antagonists naloxone and naltrexone in doses as low as 1.0 mg/kg, but not by the quaternary forms of these antagonists [4]. Peripherally a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90099-0
更新日期：1987-01-01 00:00:00
abstract：:Feeding difficulties due to their condition have been widely described for babies, children and adults with Down syndrome (DS). A previous study demonstrated that, compared with wearing a placebo appliance, wearing an occlusal appliance increased inter-arch dental contacts, improved the oral health status of adults wi...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.03.034
更新日期：2015-06-01 00:00:00
