Transgenic mouse models of Alzheimer's disease.

abstract：:GPRC6A is an amino acid-sensing receptor highly expressed in the brain and in skeletal muscle. Although recent evidence suggests that genetically engineered GPRC6A receptor knockout (KO) mice are susceptible to develop subtle endocrine and metabolic disturbances, the underlying disruptions in energy metabolism are lar...

journal_title：Physiology & behavior

authors： Clemmensen C,Pehmøller C,Klein AB,Ratner C,Wojtaszewski JF,Bräuner-Osborne H

更新日期：2013-06-13 00:00:00

abstract：:Daily rhythms in glucose tolerance have been reported for several species of mammals, which seem to be linked to factors such as daily rhythms of insulin resistance and feeding habits. In this paper, we studied entrainment to a daily scheduled meal of blood glucose after carbohydrate intake (dextrin or glucose). After...

journal_title：Physiology & behavior

authors： López-Olmeda JF,Egea-Alvarez M,Sánchez-Vázquez FJ

更新日期：2009-03-23 00:00:00

abstract：:The present experiments investigated gene expression in the amygdala following contingent taste/LiCl treatment that supports development of conditioned taste aversion (CTA). The use of whole genome chips and stringent data set filtering led to the identification of 168 genes regulated by CTA compared to non-contingent...

journal_title：Physiology & behavior

authors： Panguluri SK,Kuwabara N,Kang Y,Cooper N,Lundy RF

更新日期：2012-02-28 00:00:00

abstract：:We used the hemagglutination test to investigate differences in the specific immune response to sheep red blood cells (SRBC) of female common voles living in matriarchal groups. The applied test proved to be a useful tool for studying the effect of the social environment on the immune response in small mammals. The re...

journal_title：Physiology & behavior

authors： Heise SR,Van Acker A

更新日期：2000-11-01 00:00:00

abstract：:Feeding difficulties due to their condition have been widely described for babies, children and adults with Down syndrome (DS). A previous study demonstrated that, compared with wearing a placebo appliance, wearing an occlusal appliance increased inter-arch dental contacts, improved the oral health status of adults wi...

journal_title：Physiology & behavior

authors： Hennequin M,Mazille MN,Cousson PY,Nicolas E

更新日期：2015-06-01 00:00:00

abstract：:Repeated delivery of fast rise-time acoustic stimuli elicit cardiac changes in humans that reflect startle, orienting, and defense responses. To test the hypothesis that fast rise-time stimuli produce these responses in the rat, we evaluated magnitude, latency, and habituation of cardiovascular responses to brief airp...

journal_title：Physiology & behavior

authors： Taylor BK,Printz MP

更新日期：1996-09-01 00:00:00

abstract：:Sexually experienced male rats were injected IP with 0, 0.3, 1.5, 3.0, or 6.0 mg/kg cadmium chloride. The highest dose was fatal within 48 h of injection. A dose-related deficit in erectile function was observed in ex copula tests 48 h after injection. Copulatory dysfunction was evident in mating tests 72 h after inje...

journal_title：Physiology & behavior

authors： Clark JT,Jimenez B,Evans SL,Barrow R,Winfree M,Mrotek JJ

更新日期：1994-11-01 00:00:00

abstract：:The examples of "synergism" reported in the taste literature fit the common definition of the term but may merely reflect normal additivity in the taste system. That is, the perceived intensities of these "synergistic" mixtures exceed the sums of the perceived intensities of the unmixed taste components (addition of p...

journal_title：Physiology & behavior

authors： Rifkin B,Bartoshuk LM

更新日期：1980-06-01 00:00:00

abstract：:The oxytocin (OT) neural system is thought to be involved in the underlying mechanisms that guide the development of social behaviors. In the present study, we examined the effects of neonatal oxytocin manipulation in mice. Within 24 hours after birth, pups in the treatment group randomly received an intraperitoneal i...

journal_title：Physiology & behavior

authors： Mogi K,Ooyama R,Nagasawa M,Kikusui T

更新日期：2014-06-22 00:00:00

abstract：:Prenatal exposure to alcohol feminizes saccharin consumption patterns in adult male rats. To study the involvement of testosterone in this effect, testosterone propionate (TP) was administered to pregnant dams in an attempt to reverse that feminized saccharin consumption pattern in the male offspring. Female offspring...

journal_title：Physiology & behavior

authors： McGivern RF,Holcomb C,Poland RE

更新日期：1987-01-01 00:00:00

abstract：:We previously demonstrated that chronic dietary treatment with acarbose, an alpha-glucosidase inhibitor, improves glucose homeostasis in the streptozotocin (STZ)-induced diabetic rat. In this study we evaluated the effects of 4 weeks of acarbose treatment on glucose homeostasis in STZ-diabetic rats for both meal-fed (...

journal_title：Physiology & behavior

authors： Wright BE,Vasselli JR,Katovich MJ

更新日期：1998-03-01 00:00:00

abstract：:Dried bonito dashi is often used in Japanese cuisine with a number of documented positive health effects. Its major taste is thought to be umami, elicited by inosine 5'-monophosphate (IMP) and L-amino acids. Previously we found that lactic acid, a major component of dried bonito dashi, enhanced the contribution of man...

journal_title：Physiology & behavior

authors： Delay ER,Weaver B,Lane DR,Kondoh T

更新日期：2019-02-01 00:00:00

abstract：:The effects of substantia nigra (SN) (pars compacta) stimulation on the rage reaction elicited by ventromedial hypothalamic nucleus (VMH) were investigated in the cat. The studied parameters of the rage reaction were: the current and the frequency threshold for the appearance of the hissing and the hissing latency. A ...

journal_title：Physiology & behavior

authors： Crescimanno G,Piazza P,Benigno A,Amato G

更新日期：1986-01-01 00:00:00

abstract：:The ability of a Nal-Lys gonadotropin releasing-hormone antagonist (Antide) to suppress pituitary-testicular function and male sexual behavior was studied in seven group-living adult male rhesus monkeys. Each male received a single 15 mg/kg b.wt. subcutaneous injection of Antide dissolved in equal volumes of propylene...

journal_title：Physiology & behavior

authors： Wallen K,Eisler JA,Tannenbaum PL,Nagell KM,Mann DR

更新日期：1991-08-01 00:00:00

abstract：:Seventy women students were tested on a short battery of tasks assessing cognitive performance. They also completed self-report ratings of mood, the Dutch Eating Behaviour Questionnaire (DEBQ) to which was appended several additional items concerning their recent dieting behaviour, and a 24-h dietary recall. Heart rat...

journal_title：Physiology & behavior

authors： Green MW,Rogers PJ,Elliman NA,Gatenby SJ

更新日期：1994-03-01 00:00:00

abstract：:To evaluate whether the suprachiasmatic nuclei (SCN) control 24-h rhythmicity in cardiovascular function, rats were subjected to computerized recording of 24-h blood pressure (BP) and heart rate (HR) following SCN lesions. In sham- and nonlesioned rats, circadian patterns of BP and HR ran in phase with those in feedin...

journal_title：Physiology & behavior

authors： Janssen BJ,Tyssen CM,Duindam H,Rietveld WJ

更新日期：1994-02-01 00:00:00

abstract：:Sjogren's Syndrome (SS) patients have impaired salivary gland function and an elevated frequency of oral complaints. The taste complaints are thought to be due to sensory deficits that arise in the absence of sufficient saliva to maintain taste receptors. We assessed the subjective complaints, salivary production and ...

journal_title：Physiology & behavior

authors： Weiffenbach JM,Schwartz LK,Atkinson JC,Fox PC

更新日期：1995-01-01 00:00:00

abstract：:A device is described for eliciting acceleration concussion in the awake rat. Animals, which were manually restrained, were struck on the occipital crest by a rubber knob attached to the striker wire of a spring-loaded rat trap. This method produced concussion with survival in over 50% of animals tested. The remainder...

journal_title：Physiology & behavior

authors： Shaw NA

更新日期：1985-10-01 00:00:00

abstract：:The role of Pavlovian conditioning in humans with perennial allergic rhinitis was investigated using release of tryptase from sensitised mast cells as an indicator of allergic responsiveness. Challenge with house dust mite allergen (unconditioned stimulus) was paired with a drink of novel taste and appearance (conditi...

journal_title：Physiology & behavior

authors： Gauci M,Husband AJ,Saxarra H,King MG

更新日期：1994-05-01 00:00:00

abstract：:The role of the olfactory sense in the expression of cocaine-induced conditioned place preference (CPP) was examined in adult male rats (n = 35) of the N/Nih strain. Consistent with the scientific literature, rats were observed to significantly (p < 0.05) increase (double) the seconds spent in their least-preferred ch...

journal_title：Physiology & behavior

authors： Calcagnetti DJ,Quatrella LA,Schechter MD

更新日期：1996-04-01 00:00:00

abstract：:Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia produced by morphine injection, footshock, vaginal/cervical stimulation, and during late pregnancy in rats. The present study was designed to determine how soon after ingestion the enhancement begins and how long it lasts. Tai...

journal_title：Physiology & behavior

authors： Doerr JC,Kristal MB

更新日期：1989-11-01 00:00:00

abstract：:Wistar rats were exposed to 24-h cycles of sinusoidal varying light intensity at various amplitudes (A) and mean intensity (I) levels. The cycle minimum was at least 0.1 lux. Food approaches and wheel running activity were continuously recorded. Entrainment was observed to light cycles with amplitudes as low as 2 lux....

journal_title：Physiology & behavior

authors： Ruis JF,Rietveld WJ,Buys JP

更新日期：1991-12-01 00:00:00

abstract：:Cocoa flavanols (CF) influence physiological processes in ways that suggest their consumption may improve aspects of neural function, and previous studies have found positive influences of CF on cognitive performance. In this preliminary study we investigated whether visual, as well as cognitive, function is influence...

journal_title：Physiology & behavior

authors： Field DT,Williams CM,Butler LT

更新日期：2011-06-01 00:00:00

abstract：:This study examined spatial memory as measured by radial arm maze (RAM) performance after exposure to two stress conditions and a normothermic-unrestrained control condition. Male Fischer 344 rats were trained on the win-shift RAM procedure for 7 days, by which time they achieved asymptotic performance. The next day, ...

journal_title：Physiology & behavior

authors： Stillman MJ,Shukitt-Hale B,Levy A,Lieberman HR

更新日期：1998-07-01 00:00:00

abstract：:The present study describes an experiment that was carried out to study the effects of mixing pigs once at 25 kg, preceded by transportation for 1.5 h, on the behavior and the circadian rhythmicity of salivary cortisol. The frequency of agonistic interactions was higher for mixed pigs. This was not only the case immed...

journal_title：Physiology & behavior

authors： Ekkel ED,Savenije B,Schouten WG,Wiegant VM,Tielen MJ

更新日期：1997-07-01 00:00:00

abstract：:It is well known that several amino acids, such as arginine, are potent stimuli for insulin and glucagon secretion from the pancreas. Recently, vagal arginine sensors, which modulate arginine-induced pancreatic hormone secretion, have been reported to exist in the liver. The present investigation was designed to evalu...

journal_title：Physiology & behavior

authors： Trabelsi F,Hélie R,Bergeron R,Lavoie JM

更新日期：1995-04-01 00:00:00

abstract：:The startle behaviour of the fetus (both spontaneous and elicited) was examined in fetuses of mothers who drank alcohol and mothers who did not. Fetuses exposed to alcohol showed a higher frequency of spontaneous startles and were less likely to exhibit a normal startle in response to a vibroacoustic stimulus. These d...

journal_title：Physiology & behavior

authors： Little JF,Hepper PG,Dornan JC

更新日期：2002-08-01 00:00:00

abstract：:Binge eating disorder (BED), characterized by excessive food consumption within a discrete period of time, is the most prevalent of all eating disorders, with higher rates in women than men. Chronic stress, particularly during adolescence, is a significant risk factor for BED in women, but the mechanism underlying thi...

journal_title：Physiology & behavior

authors： Lamontagne SJ,Wilkin MM,Menard JL,Olmstead MC

更新日期：2021-01-01 00:00:00

abstract：:Environmental enrichment (EE) is an experimental model which is believed to counteract some of the effects induced by stressors, although few studies have exposed rodents simultaneously to EE and stress. Our aim was to compare the short- and long-term effects of different housing conditions in mice submitted to chroni...

journal_title：Physiology & behavior

authors： Mesa-Gresa P,Ramos-Campos M,Redolat R

更新日期：2016-05-01 00:00:00

abstract：:Propofol is a short acting intravenous anesthetic that has been used in the treatment of status epileptics. However, the occurrence of seizures in epileptic and non-epileptic patients during recovery from propofol induced anesthesia suggests that propofol may have proconvulsant effects. We have previously shown that p...

journal_title：Physiology & behavior

authors： Hasan ZA,Abdel Razzak RL,Alzoubi KH

更新日期：2014-04-10 00:00:00