Abstract：
:Fluoride ingestion has been linked to changes in behavior in mice and rats, related to dose, sex of the animal, and the timing of exposure. Previous studies have shown the behavior of female rats to be most affected by postnatal fluoride exposure, and in this study we determined the effects of postnatal fluoride exposure on anxiety related behavior and serotonin. Mice given 50 ppm fluoride in drinking water had increased entries in the open arms of the elevated plus maze, suggesting reduced anxiety. Both peripheral and central serotonin was increased in the fluoride treated mice. In a cohort of children drinking water containing 2.5 ppm fluoride, serum serotonin was also increased as compared to controls. The mechanisms by which fluoride results in an increase peripheral and central serotonin are not well understood, but warrant further study, as these effects may also be relevant to prenatal fluoride related changes in behavior in both mice and humans.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Lu F,Zhang Y,Trivedi A,Jiang X,Chandra D,Zheng J,Nakano Y,Abduweli Uyghurturk D,Jalai R,Onur SG,Mentes A,DenBesten PKdoi
10.1016/j.physbeh.2019.02.017subject
Has Abstractpub_date
2019-07-01 00:00:00pages
76-83eissn
0031-9384issn
1873-507Xpii
S0031-9384(18)30937-5journal_volume
206pub_type
杂志文章abstract：:Hyp mice are a model for X-linked hypophosphatemia, the most common form of vitamin D-resistant rickets. Previous reports indicate alterations in the nervous system of these mice. The present study examined rearing and step climbing behavior in Hyp mice in the staircase test. We found that male Hyp mice have large red...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90195-8
更新日期：1987-01-01 00:00:00
abstract：:Pleasant and unpleasant flavors and odors can modulate pain perception, and the efficacy of sweet flavors in reducing pain seems to be related to its hedonic value. Chronic variate stress paradigm is a model of depression, and is suggested to induce anhedonia. We observed previously that lithium may prevent behavioral...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.04.004
更新日期：2006-07-30 00:00:00
abstract：:The present study examined responsiveness of newborn rats to a surrogate nipple providing fluids with basic tastes (sweet, sour, bitter and salty) and assessed the effects of this first gustatory experience on subsequent responding to the nipple itself (empty nipple) or the nipple providing water. Responsiveness (atta...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00672-2
更新日期：2002-06-01 00:00:00
abstract：:The instrumental methods to induce paradoxical sleep (PS) deprivation are stressful. The modified multiple platform method (MMPM), in which animals are placed with new cohorts inside the water tanks, results in augmented ACTH and corticosterone (CORT) responses. We hypothesised that this increased response could be at...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00181-x
更新日期：2000-01-01 00:00:00
abstract：:Two experiments investigated short-term food deprivation effects on neuroendocrine processes influenced by estrogen. These studies were prompted by prior work indicating that food deprivation increased the number of immunocytochemically identified cells containing estradiol receptors in the medial preoptic area of ova...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(96)00133-3
更新日期：1996-09-01 00:00:00
abstract：:Animal shelters are an extremely stressful environment for a dog, most specifically due to social isolation and novel surroundings. The stress response of dogs housed in this environment may be alleviated through human interaction shortly after arrival. During their second day in a public animal shelter, adult stray d...
journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
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更新日期：2006-03-30 00:00:00
abstract：:Behavioral and physiological consequences of heparinoid injections, which increase plasma levels of nonesterified fatty acids (NEFA) by releasing lipoproteinlipase into the circulation, were studied in rats, because, according to the lipostatic hypothesis of food intake control, changes in plasma metabolite levels sho...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90046-x
更新日期：1983-01-01 00:00:00
abstract：:Changes in thermal environment can invoke a stress response in pigs, which in turn can potentially impact their immune system and disease susceptibility. We investigated effects of heat stress and social rank on behavior, immune responsiveness, and performance of pigs challenged with porcine reproductive and respirato...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.08.029
更新日期：2007-01-30 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90557-5
更新日期：1991-09-01 00:00:00
abstract：:Level of food restriction was manipulated in mice to assess its importance for the acquisition and expression of a conditioned odor discrimination. In training, animals were exposed to odors (either rose or lemon) presented on a piece of filter paper in a pot covered in bedding. For half of the conditioning trials, gr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00439-x
更新日期：2001-03-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00256-5
更新日期：2000-05-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90252-9
更新日期：1982-10-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.03.005
更新日期：2019-07-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.10.017
更新日期：2012-02-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90005-x
更新日期：1989-09-01 00:00:00
abstract：:During later life sleep depth (slow-wave sleep, SWS) and maintenance exhibit deleterious changes, with possible negative effects on daytime function. This study assessed the effect of chronic, supervised exercise on sleep using laboratory-based polysomnography (PSG) and repeated measures in older adults. Thirteen men ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.12.031
更新日期：2015-03-01 00:00:00
abstract：:An analysis of the gross composition of milk in five inbred strains of mice (NZB, CBA/H, BALB/c, C57BL/6, XLII) was conducted for two different days during the lactating period (6th and 9th day after parturition). The quantity of milk and the concentration of proteins, lactose and lipids were measured. Results show a ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90027-8
更新日期：1987-01-01 00:00:00
abstract：:Neuroanatomical and electrophysiological techniques have provided insights into the organization of the spinal cord circuitry and the neurotransmitter mechanisms involved in primitive voiding reflexes in neonatal animals. Patch clamp studies of unitary synaptic transmission in spinal cord slice preparations indicate t...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/s0031-9384(02)00919-8
更新日期：2002-12-01 00:00:00
abstract：:A double sampling procedure, developed originally for investigation of liquid phase gastric emptying in humans, is adapted for use in the rat. The double sampling technique permits repeated measurement of gastric volume, allowing a determination of a time course of emptying in a single experimental session. Further, t...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90226-5
更新日期：1987-01-01 00:00:00
abstract：:Female rats which had been ovariectomized either 7 days earlier (short-term deprivation, N = 11) or 35 days earlier (long-term deprivation, N = 11) were tested for their response to treatments of estradiol benzoate (6.0 micrograms/kg body weight) and progesterone (1.2 mg/kg). The long-term deprived females showed less...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90253-7
更新日期：1985-12-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
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更新日期：2016-08-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90201-c
更新日期：1992-01-01 00:00:00
abstract：:Food-deprived meadow voles were used to test predictions of two hypotheses associated with the recovery of sexual behaviors following re-feeding. Specifically, we tested between the body weight set point and metabolic fuels hypotheses. To do so, we determined whether the body weight of previously food-deprived female ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.02.003
更新日期：2005-03-31 00:00:00
abstract：:Forty-two nondieting adult males were given 8 or 16 oz of lemonade, sweetened to equal intensity with either aspartame or sucrose, or the same volumes of water, or no drink. Subjects were separated into three groups receiving the drinks at different times: with a self-selection lunch, or 30, or 60 min before lunch. Fo...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90254-2
更新日期：1990-07-01 00:00:00
abstract：:Five pigeons were allowed one hour of access to food after variable intervals of deprivation averaging 23 hours. Five other pigeons were allowed one hour of food after fixed 23 hour intervals. It was found that the amount eaten by birds in an environment continually alternating between deprivation and one-hour ad lib ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90249-4
更新日期：1983-06-01 00:00:00
abstract：:Adolescence and excessive intake of saccharin have each been previously associated with enhanced vulnerability to drug abuse. In the present study, we focused on the relationship between these two factors using male adolescent and adult rats selectively bred for high (HiS) and low (LoS) levels of saccharin intake. On ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.02.001
更新日期：2007-05-16 00:00:00
abstract：:Anodal direct currents of 1 or 10 microA were unilaterally applied for 30 min once a day to the premotor area of the cerebral cortex in rabbits, in which the current application was repeated 10 times at intervals of 2-3 days. Peripheral motor behavior was observed during and after each polarization trial, and was comp...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90482-h
更新日期：1992-12-01 00:00:00
abstract：:This report describes a standard procedure for studying the disordered eating behavior of bulimic patients in a laboratory setting. Test meals were given to eight normal weight women with bulimia under four different conditions on non-consecutive days. On day 1 they were asked to consume as much as they "would normall...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90426-9
更新日期：1986-10-01 00:00:00
abstract：:Binge eating disorder (BED), characterized by excessive food consumption within a discrete period of time, is the most prevalent of all eating disorders, with higher rates in women than men. Chronic stress, particularly during adolescence, is a significant risk factor for BED in women, but the mechanism underlying thi...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113194
更新日期：2021-01-01 00:00:00
abstract：:The deterioration of homeostasis between oxidant/antioxidant species may represent an important mechanism linking psychological stress to cardiovascular risk despite the many sex differences in stress responsiveness. The goal of the present study was to investigate the influence of chronic mild stress (CMS), a widely ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.05.011
更新日期：2009-08-04 00:00:00
