Abstract:
:Functional recovery after oculomotor nerve injury is very poor. Electrical stimulation has been shown to promote regeneration of injured nerves. We hypothesized that electrical stimulation would improve the functional recovery of injured oculomotor nerves. Oculomotor nerve injury models were created by crushing the right oculomotor nerves of adult dogs. Stimulating electrodes were positioned in both proximal and distal locations of the lesion, and non-continuous rectangular, biphasic current pulses (0.7 V, 5 Hz) were administered 1 hour daily for 2 consecutive weeks. Analysis of the results showed that electrophysiological and morphological recovery of the injured oculomotor nerve was enhanced, indicating that electrical stimulation improved neural regeneration. Thus, this therapy has the potential to promote the recovery of oculomotor nerve dysfunction.
journal_name
Neural Regen Resjournal_title
Neural regeneration researchauthors
Du L,Yang M,Wan L,Wang XH,Li STdoi
10.4103/1673-5374.193248subject
Has Abstractpub_date
2016-10-01 00:00:00pages
1666-1669issue
10eissn
1673-5374issn
1876-7958pii
NRR-11-1666journal_volume
11pub_type
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