Abstract：
:C-4 and C-6 bridged haptens of 11 alpha-hydroxyprogesterone, an anti-androgen, were respectively synthesized via 4, 5 and 5 alpha, 6 alpha epoxide ring openings using 3-mercaptopropanoic acid. Substitution of 6-bromo derivative of progesterone using the same reagent unexpectedly afforded a C-4 substituted product instead of the normal C-6 substituted product previously reported in the literature.
journal_name
Steroidsjournal_title
Steroidsauthors
Yoshida H,Nakai S,Nimbari F,Yoshimoto K,Nishimura Tdoi
10.1016/0039-128x(89)90063-9subject
Has Abstractpub_date
1989-06-01 00:00:00pages
727-38issue
6eissn
0039-128Xissn
1878-5867pii
0039-128X(89)90063-9journal_volume
53pub_type
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