当前位置： SCI文献检索 > THROMBOSIS RESEARCH期刊下所有文献 > ABO blood group is associated with peripheral arterial disease in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA).

ABO blood group is associated with peripheral arterial disease in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA).

Abstract：

INTRODUCTION:Peripheral artery disease (PAD) affects 8.5 million Americans and thus improving our understanding of PAD is critical to developing strategies to reduce disease burden. The objective of the study was to determine the association of ABO blood type with ankle brachial index (ABI) as well as prevalent and incident PAD in a multi-ethnic cohort. METHODS:The Multi-Ethnic Study of Atherosclerosis includes non-Hispanic White, African, Hispanic, and Chinese Americans aged 45-84. ABO blood type was estimated using ABO genotypes in 6027 participants who had ABI assessed at the baseline exam. Associations with ABO blood type were evaluated categorically and under an additive genetic model by number of major ABO alleles. After excluding those with ABI>1.4, prevalent PAD was defined as ABI≤0.9 at baseline and incident PAD as ABI≤0.9 for 5137 participants eligible for analysis. RESULTS:There were 222 prevalent cases and 239 incident cases of PAD. In African Americans, each additional copy of the A allele was associated with a 0.02 lower baseline ABI (p=0.006). Each copy of the A allele also corresponded to 1.57-fold greater odds of prevalent PAD (95% CI, 1.17-2.35; p=0.004), but was not associated with incident PAD. No associations were found in other racial/ethnic groups for ABI, prevalent PAD, or incident PAD across all races/ethnicities. CONCLUSIONS:Blood type A and the A allele count were significantly associated with baseline ABI and prevalent PAD in African Americans. Further research is needed to confirm and study the mechanisms of this association in African Americans.

journal_name

Thromb Res

journal_title

Thrombosis research

authors

Pike MM,Larson NB,Wassel CL,Cohoon KP,Tsai MY,Pankow JS,Hanson NQ,Decker PA,Berardi C,Alexander KS,Cushman M,Zakai NA,Bielinski SJ

doi

10.1016/j.thromres.2017.02.018

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

1-6

eissn

0049-3848

issn

1879-2472

pii

S0049-3848(17)30053-1

journal_volume

153

pub_type

杂志文章

相关文献

THROMBOSIS RESEARCH文献大全
  • The effect of sulphinpyrazone on whole blood thromboxane and prostacyclin generation in man.

    abstract：:A new method, based on the observation that leukocytes contain PGI2-synthetase activity, was used to measure the effect of pharmacological levels of sulphinpyrazone on the TXA2 and PGI2 production in whole blood. Four human volunteers took 400 mg sulphinpyrazone twice daily for 5 1/2 days. Blood was drawn before the s...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(82)90033-0

    authors： Badenhorst PN,Deckmyn H,Vermylen J

    更新日期：1982-10-01 00:00:00

  • Potentiation of wheat germ agglutinin aggregation of platelets by von Willebrand protein and by a 116,000 molecular weight tryptic fragment.

    abstract：:This study compares selected properties of purified tryptic fragments of human von Willebrand (vW) protein in order to better understand how the M(r) 116,000 fragment retains activity in ristocetin-induced platelet agglutination. Wheat germ agglutinin (WGA) aggregation of platelet-rich plasma was potentiated by preinc...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(83)90408-5

    authors： Martin SE,Francis CW,Marder VJ

    更新日期：1983-08-01 00:00:00

  • Low dose of aPCC after the initial treatment in acquired haemophilia A is useful to reduce bleeding relapses: Data from the FAIR registry.

    abstract：BACKGROUND:Bypassing agents are the first line therapy in patients with acquired haemophilia A (AHA). Activated prothrombin complex concentrate (aPCC) proved to be effective as initial treatment, but 20% of patients (pts) had relapses. aPCC as short-term prophylaxis to reduce subsequent bleeds is still not clear. AIM:...

    journal_title：Thrombosis research

    pub_type： 信件

    doi：10.1016/j.thromres.2018.12.006

    authors： Zanon E,Pasca S,Siragusa S,Napolitano M,Santoro C,Mameli L,Rocino A,FAIR Study Group.

    更新日期：2019-02-01 00:00:00

  • A new model of arterial thrombosis.

    abstract：:A new model of arterial thrombosis in rats was based on a combination of a localizing hemodynamic factor /partial mechanical constriction of aorta/, generalized mild endothelial lesion /i.v.hypotonic saline/ and a humoral factor/i.v. serotonin/. The resulting aortic occlusion was indicated by measuring rectal temperat...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(86)90362-2

    authors： Hladovec J

    更新日期：1986-03-01 00:00:00

  • Changes in thrombomodulin level in plasma of endotoxin-infused rabbits.

    abstract：:Changes in the plasma thrombomodulin (TM) level were examined in endotoxin-infused rabbits. The plasma TM level in normal rabbits was 143.8 +/- 8.4 ng/ml (n = 67) and the molecular weight of the major TM was about 55 kd. Endotoxin (lipopolysaccharide, LPS, E. Coli B8:0127) was intravenously infused. LPS infusion incre...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(92)90240-b

    authors： Sawada K,Yamamoto H,Matsumoto K,Yago H,Suehiro S,Tahara C,Ishii H,Kazama M,Abe T

    更新日期：1992-01-15 00:00:00

  • Pressure influences the rate of fibrin polymerization: decompression accelerates, compression decelerates.

    abstract：:We report here that the rate of fibrin polymerization is accelerated by decompression: the rate is essentially doubled by reducing the pressure by one-half (380 torr, 14.7 PSI or 1/2 ATM) and increased by 3.6 times with respect to the control at 25 torr (0.48 PSI or 1/30th ATM). We also report here that the rate of fi...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(88)90251-4

    authors： Murayama M

    更新日期：1988-03-15 00:00:00

  • A two-step approach (Enzyme-linked immunosorbent assay and confirmation assay) to detect antibodies against von Willebrand factor in patients with Acquired von Willebrand Syndrome.

    abstract：BACKGROUND:Acquired von Willebrand Syndrome is a rare bleeding disorder, which arises in individuals with no personal or family history of bleeding, associated with lymphoproliferative and myeloproliferative disorders or other diseases. AIM:To develop a two-step approach assay to detect autoantibodies against VWF and ...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2014.09.020

    authors： Franchi F,Biguzzi E,Stufano F,Siboni SM,Baronciani L,Peyvandi F

    更新日期：2014-12-01 00:00:00

  • Premature arterial and venous events in three families. Effect of folate levels and MTHFR mutation mediated by family/generation and homocysteine levels.

    abstract：:Plasma homocysteine levels result from the effect of genetic and environmental factors. We investigated the hypothesis of familial association between folates, methylenetetrahydrofolate reductase (MTHFR) and hyperhomocysteinemia with acute events, studying three families through pedigree analysis and log-linear graphi...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/s0049-3848(01)00408-x

    authors： Assanelli D,Grassi M,Bonanome A,Salvadori G,Bonetti P,Boldini A,Archetti S,Ruggeri G,Pezzini A,Pagnan A

    更新日期：2002-01-15 00:00:00

  • Risk of bleeding in low-risk atrial fibrillation patients on warfarin waiting for elective cardioversion.

    abstract：INTRODUCTION:Systemic embolism is the most serious complication of cardioversion of atrial fibrillation (AF) and the immediate post-cardioversion period is associated with increased risk for thrombus formation. For this reason, treatment with vitamin K antagonist (VKA) is recommended for patients with AF. No informatio...

    journal_title：Thrombosis research

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.thromres.2011.08.031

    authors： Poli D,Antonucci E,Grifoni E,Paoletti O,Rancan E,Dentali F,Testa S

    更新日期：2012-05-01 00:00:00

  • Improvement of anticoagulant treatment using a dynamic decision support algorithm: a Danish Cohort study.

    abstract：INTRODUCTION:Warfarin is the most widely prescribed vitamin K antagonist and in the United States and Europe more than 10 million people are currently in long-term oral anticoagulant treatment. This study aims to retrospectively validate a dynamic statistical model providing dosage suggestions to patients in warfarin t...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2013.12.042

    authors： Nielsen PB,Lundbye-Christensen S,Rasmussen LH,Larsen TB

    更新日期：2014-03-01 00:00:00

  • Cardioprotective effects of defibrotide in acute myocardial ischemia in the cat.

    abstract：:We investigated the effects of Defibrotide (D), a natural polydeoxyribonucleotide, on acute myocardial ischemia (AMI) in anesthetized cats. A permanent ligature was placed around the left anterior descending coronary artery (LAD) 12-14 mm from its origin. Ventricular fibrillation and death were exceptional and when th...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(85)90008-8

    authors： Niada R,Porta R,Pescador R,Mantovani M,Prino G

    更新日期：1985-04-01 00:00:00

  • Platelet-leukocyte interactions in thrombosis.

    abstract：:Activated platelets may adhere to leukocytes and form circulating mixed aggregates. The latter are considered a reliable marker of a prothrombotic state and are associated with several cardiovascular conditions. The molecular mechanisms responsible of this cellular interaction include a central role of platelet P-sele...

    journal_title：Thrombosis research

    pub_type： 杂志文章,评审

    doi：10.1016/j.thromres.2011.10.010

    authors： Cerletti C,Tamburrelli C,Izzi B,Gianfagna F,de Gaetano G

    更新日期：2012-03-01 00:00:00

  • MiR-188-3p upregulation results in the inhibition of macrophage proinflammatory activities and atherosclerosis in ApoE-deficient mice.

    abstract：BACKGROUND:Atherosclerosis occurs as a result of a chronic inflammatory response in the arterial wall associated with an increased uptake of low-density lipoprotein by macrophages and the subsequent transformation of this lipoprotein into foam cells. It has been found that miR-188-3p can suppress autophagy and myocardi...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2018.09.043

    authors： Zhang XF,Yang Y,Yang XY,Tong Q

    更新日期：2018-11-01 00:00:00

  • Alpha-tocopherol, a potent modulator of endothelial cell function.

    abstract：:The effect of alpha-tocopherol on various endothelial cell functions was evaluated in vitro using cultures of human umbilical vein endothelial cells. Prostacyclin synthesis, plasminogen activator activity and von Willebrand factor activity were evaluated in control and alpha-tocopherol supplemented cultures. Alpha-toc...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(88)90203-4

    authors： Huang N,Lineberger B,Steiner M

    更新日期：1988-05-15 00:00:00

  • Assessment for evidence of non A-non B hepatitis in patients given n-heptane-suspended heat-treated clotting factor concentrates.

    abstract：:Nineteen patients, (2 adults, 17 children) with inherited bleeding disorders were infused with n-heptane-suspended-heated clotting factor concentrates. Twelve of the nineteen were previously untreated. Six patients were infused with Profilnine Heat-Treated and 13 with Profilate Heat-Treated. Five separate centers part...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(87)90074-0

    authors： Carnelli V,Gomperts ED,Friedman A,Aledort L,Hilgartner M,Dietrich S,Fedor EJ

    更新日期：1987-06-15 00:00:00

  • The effects of angiotensin II and genetic hypertension upon extracellular nucleotide hydrolysis by rat platelet ectoenzymes.

    abstract：:The extracellular nucleotides, ATP and ADP, as well as adenosine have been implicated in a great number of physiological functions. ADP is one of the major platelet recruiting factors, whereas ATP is considered to be a competitive inhibitor of ADP-induced platelet aggregation and adenosine is able to induce vasodilata...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2007.01.006

    authors： Fürstenau CR,Trentin DS,Barreto-Chaves ML,Sarkis JJ

    更新日期：2007-01-01 00:00:00

  • Preoperative direct oral anticoagulants treatment and all-cause mortality in elderly patients with hip fracture: A retrospective cohort study.

    abstract：INTRODUCTION:Hip fracture is common among the elderly and is associated with increased morbidity and mortality, particularly when surgery is delayed. Direct oral anticoagulants (DOACs) use might increase bleeding and postpone hip repair surgery. We aimed to assess the association between preoperative DOACs use and adve...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2020.03.002

    authors： Saliba W,Arbel A,Abu-Full Z,Cohen S,Rennert G,Preis M

    更新日期：2020-05-01 00:00:00

  • The activation of plasminogen by T-PA-PAI-1 complex in the absence of fibrin.

    abstract：:The activity of tissue plasminogen activator-plasminogen activator inhibitor-1 (t-PA-PAI-1) complex to convert plasminogen to plasmin was examined by using fibrin autography and casein zymography where plasminogen was added or removed for casein layer. Fibrin autography was more sensitive to the activity of t-PA even ...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(91)90279-6

    authors： Takada Y,Takada A

    更新日期：1991-07-01 00:00:00

  • The role of biomarkers of endothelial activation in predicting morbidity and mortality in patients with severe sepsis and septic shock in intensive care: A prospective observational study.

    abstract：INTRODUCTION:Endothelial dysfunction plays an essential role in the pathogenesis of sepsis. The study aimed to illustrate the associations between the dynamic change (from day 1 to day 7) in biomarker concentration of endothelial dysfunction and outcomes in severe sepsis and septic shock in the intensive care unit (ICU...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2018.09.059

    authors： Fang Y,Li C,Shao R,Yu H,Zhang Q

    更新日期：2018-11-01 00:00:00

  • Anticoagulant effects of an antidiabetic drug on monocytes in vitro.

    abstract：INTRODUCTION:Monocyte- and microparticle (MP)-associated tissue factor (TF) is upregulated in diabetes. Lipopolysaccharide (LPS) induces expression of TF and alternatively spliced TF (asTF) and increases MP release from monocytes. Using LPS-stimulated TF-bearing human monocytes, we examined whether glibenclamide, a sul...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2011.07.007

    authors： Henriksson CE,Hellum M,Haug KB,Aass HC,Joø GB,Øvstebø R,Trøseid AM,Klingenberg O,Kierulf P

    更新日期：2011-11-01 00:00:00

  • Fibrinogen does not protect von Willebrand factor against proteolysis by human cathepsin G.

    abstract：:The susceptibility of von Willebrand factor /vWF/ to digestion by human neutrophil cathepsin G in highly purified FVIII/vWF concentrate /BHS/ and in cryoprecipitate has been studied. In contrast to human neutrophil elastase, cathepsin G inactivates and degrades vWF not only in BHS but also in cryoprecipitate. Fibrinog...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(91)90657-i

    authors： Jeleńska M,Kopeć M,Sopata I,Vigh Z,Scharrer I,Breddin K

    更新日期：1991-02-15 00:00:00

  • First visualization of circulating neutrophil extracellular traps using cell fluorescence during human septic shock-induced disseminated intravascular coagulation.

    abstract：:Disseminated intravascular coagulation (DIC) is a severe complication of septic shock. Polymorphonuclear neutrophils (PMNs) may play a key role in septic shock-induced DIC via the release of neutrophils extracellular traps (NETs). NETs capture invading pathogens, but also act as a pro-coagulant surface at the interfac...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2019.09.036

    authors： Stiel L,Mayeur-Rousse C,Helms J,Meziani F,Mauvieux L

    更新日期：2019-11-01 00:00:00

  • Pro- and anti-inflammatory effects of histamine on tissue factor and TNFα expression in monocytes of human blood.

    abstract：BACKGROUND:Histamine is classified as an inflammatory mediator and has been reported to have anti- as well as pro-inflammatory properties. The aim of this study was to explore the role of histamine on the production of LPS-induced tissue factor (TF) activity and TNFα in monocytes of whole blood in the absence and prese...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2013.12.022

    authors： Østerud B,Olsen JO

    更新日期：2014-03-01 00:00:00

  • Proaggregatory and inhibitory effects of 2-O-ethyl analogues of platelet-activating factor (PAF) on human and rabbit platelets.

    abstract：:A series of 8 analogues of platelet-activating factor (PAF) in which both the acetyl group and the polar head are changed, were tested for biological activities on human and rabbit platelets in plasma. Two of these compounds, 1-O-hexadecyl-2-O-ethyl-rac-glycero-3-phosphoric acid-5'-trimethylammoniumpentyl ester and 1-...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(88)90244-7

    authors： Hofmann B,Ostermann G,Kertscher HP,Till U

    更新日期：1988-02-15 00:00:00

  • Heparanase procoagulant effects and inhibition by heparins.

    abstract：:Heparanase is an endo-beta-D-glucuronidase capable of cleaving heparan sulfate (HS) side chains of heparan sulfate proteoglycans (HSPG) on cell surfaces and the extracellular matrix, activity that is strongly implicated in tumor metastasis and angiogenesis. Evidence was provided that heparanase over-expression in canc...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/S0049-3848(10)70018-9

    authors： Nadir Y,Brenner B

    更新日期：2010-04-01 00:00:00

  • Comparison of the binding character of triflavin on resting and activated alpha(IIb)beta(3) integrin in human platelets by electron microscopy.

    abstract：:Triflavin, an Arg-Gly-Asp (RGD)-containing disintegrin purified from venom peptide inhibited platelet aggregation by interfering with the interaction of fibrinogen with alpha(IIb)beta(3) integrin. Using an immunostaining technique and electron microscopy, we investigated and compared the distribution of triflavin bind...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/s0049-3848(03)00104-x

    authors： Chuang WJ,Wu CH,Huang HN,Chen SH,Hsiao G,Lin CH,Sheu JR

    更新日期：2003-01-01 00:00:00

  • Platelet adherence and thrombus formation with flowing human blood on atherosclerotic plaque: reduced thrombogenicity of Watanabe-heritable hyperlipidemic rabbit aortic subendothelium.

    abstract：:Platelet adherence and aggregation are important in the development of ischemic sequelae in atherosclerosis. To directly examine platelet interaction with plaque, everted, deendothelialized aortic fibrous plaques from Watanabe-heritable hyperlipidemic rabbits were exposed to flowing human blood in an annular perfusion...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(89)90040-6

    authors： Lawrence JB,Prevosti LG,Kramer WS,Lu DY,Leon MB

    更新日期：1989-04-15 00:00:00

  • Hemorrhagic and thrombotic complications in bone marrow transplant recipients.

    abstract：:Hemostatic challenges occur throughout the period of stem cell transplantation (SCT). Endothelial cells injury due to chemotherapy, growth factors, intravenous catheter, and graft-versus-host disease and profound thrombocytopenia are the major components involved in the hemostatic complications. Diffuse alveolar hemor...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/S0049-3848(07)70136-6

    authors： Nadir Y,Brenner B

    更新日期：2007-01-01 00:00:00

  • The antithrombotic effect of aspirin and dipyridamole in relation to prostaglandin synthesis.

    abstract：:The antithrombotic effect of aspirin (ASA) and dipyridamole (DIP) was evaluated in rabbits in which platelet thromboxane A2 (TXA2) and arterial prostacyclin (PGI2) were measured. An intracarotid cannula thrombosis model previously shown to be sensitive to antiplatelet agents was used. Prostaglandins were determined by...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(83)90224-4

    authors： Louie S,Gurewich V

    更新日期：1983-05-15 00:00:00

  • The activity of constitutive nitric oxide synthase is increased by the pathway cAMP/cAMP-activated protein kinase in human platelets. New insights into the antiaggregating effects of cAMP-elevating agents.

    abstract：:Human platelets synthesize nitric oxide (NO) through an endothelial-type NO synthase (ecNOS) activated also by substances enhancing 3',5'-cyclic adenosine monophosphate (cAMP) concentrations, such as catecholamines, beta-adrenoceptor agonists and adenosine. To verify whether cAMP directly activates ecNOS through the c...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2004.06.036

    authors： Russo I,Doronzo G,Mattiello L,De Salve A,Trovati M,Anfossi G

    更新日期：2004-01-01 00:00:00