Pressure influences the rate of fibrin polymerization: decompression accelerates, compression decelerates.

abstract：INTRODUCTION:Growth differentiation factor-15 (GDF-15) has been identified as a predictor in cardiovascular diseases and acute pulmonary embolism. However, the association of GDF-15 and deep venous thrombosis (DVT) remains unclear. This study aimed to investigate levels of GDF-15 in patients with DVT, and determine its...

journal_title：Thrombosis research

authors： Liang W,Wei F,Yang C,Xie F,Shuai XX,Wang M,Yu M

更新日期：2020-03-01 00:00:00

abstract：:Practice variation, the differences in clinical management between physicians, is one reason why patient outcomes may differ. Identifying factors that contribute to practice variation in areas of clinical uncertainty or equipoise may have implications for understanding and improving patient care. To discern what facto...

journal_title：Thrombosis research

authors： Skeith L,Gonsalves C

更新日期：2017-11-01 00:00:00

abstract：:The thrombin inhibitory role of antithrombin III (ATIII) and heparin cofactor II (HCII) was studied in vitro using intact and injured rabbit aortae. When intact vessels were loaded with thrombin and then exposed to either heat defibrinogenated human plasma (HDHP) or ATIII the same degree of thrombin inhibition was ach...

journal_title：Thrombosis research

authors： Pasche B,Swedenborg J,Frebelius S,Olsson P

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the role of filter implantation in reducing the incidence of fatal pulmonary embolism during the endovascular treatment of thrombosis in the major tributary of the superior vena cava (SVC). METHODS:From October 2004 to October 2008, we conducted a cohort study of 40 patients with thrombosis of t...

journal_title：Thrombosis research

authors： Liang Z,Han R,Qu Y,Cao W,Cui J

更新日期：2014-07-01 00:00:00

abstract：INTRODUCTION:Pathogenesis of idiopathic pulmonary arterial hypertension (iPAH) includes endothelial dysfunction and in situ thrombosis. A hypercoagulable state has also been postulated but never demonstrated. Our objective was to determine whether patients with iPAH had a hypercoagulable state using calibrated automate...

journal_title：Thrombosis research

authors： Tournier A,Wahl D,Chaouat A,Max JP,Regnault V,Lecompte T,Chabot F

更新日期：2010-12-01 00:00:00

abstract：:Three collagenases were purified from the culture medium of human skin fibroblasts using ammonium sulfate fractionation, ion-exchange chromatography and gel filtration. The cationic collagenase had a molecular weight of 42,000; two anionic collagenases had molecular weights of 63,000 and 115,000. Preincubation of the ...

journal_title：Thrombosis research

authors： Pisoni R,Ciaglowski RE,Brown RK,Walz DA

更新日期：1984-07-15 00:00:00

abstract：INTRODUCTION:Patients with type 1 diabetes have high risk of developing microvascular complications, and microangiopathy contributes to premature cardiovascular disease in this population. The role that microvesicles (MVs) may play in the development of microangiopathy in type 1 diabetes remains unclear. MATERIALS AND...

journal_title：Thrombosis research

authors： Bergen K,Mobarrez F,Jörneskog G,Wallén H,Tehrani S

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Viscoelastometry enables rapid evaluation of coagulopathy in settings such as cardiac surgery but may be influenced by red cell concentration. METHODS:In order to study the effects of supra-physiological red cell concentrations on viscoelastometry, we compared ROTEM® viscoelastometry and plasma coagulatio...

journal_title：Thrombosis research

authors： Westbury SK,Lee K,Reilly-Stitt C,Tulloh R,Mumford AD

更新日期：2013-08-01 00:00:00

abstract：:The presence of Factor XIII subunit a was demonstrated in human monocytes by immunoperoxidase staining using specific antisera against Factor XIII and its subunits. This finding was verified by immunobiochemical techniques, as well. In an immunoblotting system after SDS polyacrylamide gel electrophoresis of denatured ...

journal_title：Thrombosis research

authors： Muszbek L,Adány R,Szegedi G,Polgár J,Kávai M

更新日期：1985-02-01 00:00:00

abstract：:Activation of plasma plasminogen to plasmin is the objective of current strategies for thrombolytic therapy. Although thrombolytic activity in blood involves a large cellular component as well as that in plasma, the contribution of this cellular phase to clinical thrombolysis has not been examined. Using a 125I-fibrin...

journal_title：Thrombosis research

authors： Langleben D,Moroz LA,Schlesinger RD

更新日期：1990-07-15 00:00:00

abstract：:Advances in antithrombotic therapy began when traditional anticoagulant agents such as heparin and the vitamin K antagonists like Coumadin became commercially available in the 1940s and 1950s. Inherent limitations of these compounds, including the need for monitoring and multiple food and drug interactions (with couma...

journal_title：Thrombosis research

authors： Spyropoulos AC

更新日期：2008-01-01 00:00:00

abstract：:We investigated the relationship between the procoagulant protease-inhibitory activity and the N-glycan structures in urinary protein C inhibitor (uPCI) by sequential exoglycosidase digestions based on the N-glycan structures elucidated in this report. uPCI was glycosylated on the three potential N-glycosylation sites...

journal_title：Thrombosis research

authors： Izutani W,Fujita M,Nishizawa K,Koga J

更新日期：2001-10-01 00:00:00

abstract：INTRODUCTION:Pseudoprolongation of activated partial thromboplastin time (APTT) is a serious problem in anticoagulation therapy for patients with high hematocrit, such as cyanotic congenital heart diseases. APTT pseudoprolongation occurs when APTT assay is performed using routinely used vacuum sampling tubes containing...

journal_title：Thrombosis research

authors： Kanahara M,Kai H,Okamura T,Wada T,Suda K,Imaizumi T,Sagawa K

更新日期：2008-01-01 00:00:00

abstract：:The fibrin sleeve of venous catheters (VC) and parietal thrombi represent frequent and dangerous side-effects of central venous catheterization (CVC), due to the risk of embolism. Reduced levels of coagulation clotting factors inhibitors (such as Antithrombin III) are known to be associated with increased thrombogenic...

journal_title：Thrombosis research

authors： De Cicco M,Matovic M,Balestreri L,De Angelis V,Fracasso A,Morassut S,Coran F,Babare R,Buonadonna A,Testa V

更新日期：1995-04-15 00:00:00

abstract：:Liquid permeation studies of fibrin gels, which were formed in the presence of thrombin (Fibrin II) and in the presence of Batroxobin (Fibrin I), showed that those gels have distinctly different flow properties. For both gels the permeability coefficient (Ks) and average pore size varied depending on the conditions fo...

journal_title：Thrombosis research

authors： Blombäck B,Okada M

更新日期：1982-01-01 00:00:00

abstract：:Venous thromboembolism remains an important cause of maternal mortality. For women at risk during pregnancy, the recommended venous thromboembolismprophylaxis is unfractionated heparin. Low molecular weight heparins, such as dalteparin, also may be suitable, but randomised trials have not been performed. Pregnant wome...

journal_title：Thrombosis research

authors： Pettilä V,Kaaja R,Leinonen P,Ekblad U,Kataja M,Ikkala E

更新日期：1999-11-15 00:00:00

abstract：:Prothrombin time is a standard screening test to monitor patients treated with oral anticoagulants. We hypothesize that INR measurements will not vary a lot within a given day in a given patient. The present study was thus conducted to compare the change of the international normalized ratio (INR) of prothrombin time ...

journal_title：Thrombosis research

authors： Ho CH,Lin MW,You JY,Chen CC,Yu TJ

更新日期：2002-09-01 00:00:00

abstract：:We previously found evidence (based on the use of 5HT as a marker) that i.v. injection of a lipopolysaccharide (LPS) into mice induces a rapid accumulation of platelets in liver and lung. Our previous studies lacked measurement of the platelet count itself, but we have now compared the LPS-induced changes in 5HT level...

journal_title：Thrombosis research

authors： Ohtaki Y,Shimauchi H,Yokochi T,Takada H,Endo Y

更新日期：2002-12-15 00:00:00

abstract：:beta-Factor XIIa (beta-XIIa, Mr approximately 30,000) was isolated from human plasma by a procedure which utilized, as an initial step, the adsorption of Factor XII to celite. Activation of Factor XII and subsequent release of beta-XIIa was brought about by the proteolytic action of co-adsorbed kallikrein. Two success...

journal_title：Thrombosis research

authors： Tankersley DL,Alving BM,Finlayson JS

更新日期：1982-02-15 00:00:00

abstract：:A significantly higher platelet malondialdehyde-like material (MDA--LM) content after physical and N-ethylmaleimide (NEM) stimulation is found in chronic ischemic heart disease (CHD) patients when compared to the control group. In subjects under aspirin treatment "in vivo" (1 gr/day) no difference is found between CHD...

journal_title：Thrombosis research

authors： Valles J,Aznar J,Santos MT,Fernandez MA

更新日期：1982-09-01 00:00:00

abstract：:Hemorrhagic tendency is frequent in uremic patients and is often associated with prolonged bleeding time and decreased platelet functions in vitro. Similarly, in multiple myeloma, platelet functions are affected, mainly by the inhibitory effect of paraprotein. We have studied patients with renal insufficiency and mult...

journal_title：Thrombosis research

authors： Cieslar P,Másová L,Scheiner T,Rysavá J,Krízová P,Danzigová Z,Spicka I,Tesar V

更新日期：2002-02-15 00:00:00

abstract：:Resistance to Activated Protein C (APC) was evaluated using 3 different methods: two of them were based on the prolongation of the Activated Partial Thromboplastin Time (APTT) using 2 different APTT reagents in the presence of APC, whereas the third method was based on the prolongation of prothrombin time when APC is ...

journal_title：Thrombosis research

authors： Vasse M,Leduc O,Borg JY,Chrétien MH,Monconduit M

更新日期：1994-10-01 00:00:00

abstract：:Cell lysates of the human monoblastic leukemia cell line, THP-1, have procoagulant activity (PCA) that is Ca++-dependent and not demonstrable in either Factor VII-, or Factor X-deficient plasma. The PCA of THP-1 cells was enhanced by human recombinant tumor necrosis factor-alpha (TNF-alpha) up to five fold. There was ...

journal_title：Thrombosis research

authors： Tanaka M

更新日期：1989-10-15 00:00:00

abstract：BACKGROUND:An association between high red cell distribution width (RDW) and venous thromboembolism (VTE) has been observed. However, it is not known whether this association differs within various manifestations of VTE, nor if there is an interaction between RDW and thrombophilia abnormalities on the risk of VTE. AIM...

journal_title：Thrombosis research

authors： Bucciarelli P,Maino A,Felicetta I,Abbattista M,Passamonti SM,Artoni A,Martinelli I

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Arterial calcification is associated with increased risk of cardiovascular events. Osteoprotegerin (OPG) is a cytokine involved in the bone metabolism and vascular calcification. Recent data support a relationship between high serum levels of OPG and increased risk for cardiovascular disease in human. The ai...

journal_title：Thrombosis research

authors： Guldiken B,Guldiken S,Turgut B,Turgut N,Demir M,Celik Y,Arikan E,Tugrul A

更新日期：2007-01-01 00:00:00

abstract：:The Calibrated Automated Thrombogram (CAT), a plate-based assay that measures thrombin generation and inhibition in plasma samples, is modified to measure the procoagulant activity of phospholipid associated with plasma microparticles (MP). The assay uses a tissue factor trigger without addition of 4 μM exogenous phos...

journal_title：Thrombosis research

authors： Owen BA,Xue A,Heit JA,Owen WG

更新日期：2011-01-01 00:00:00

abstract：:Low circulating protein C (PC) levels have been observed in sepsis, especially in patients with Neisseriae Meningitides infections. Poor clinical outcome and high limb amputation rates have been associated in infected patients with low circulating PC levels. Published studies using activated PC replacement therapy pat...

journal_title：Thrombosis research

authors： Piccin A,O' Marcaigh A,Mc Mahon C,Murphy C,Okafor I,Marcheselli L,Casey W,Claffey L,Smith OP

更新日期：2014-07-01 00:00:00

abstract：:Previous studies indicated that human placental anticoagulant protein, a member of the lipocortin family, prolonged the clotting time of normal plasma when clotting was induced by brain thromboplastin or by kaolin in the presence of cephalin and calcium. Using a two-stage amidolytic assay to assess factor X activation...

journal_title：Thrombosis research

authors： Kondo S,Noguchi M,Funakoshi T,Fujikawa K,Kisiel W

更新日期：1987-11-15 00:00:00

abstract：:Preanalytical and biological variability both have strong influences on test results of coagulation. Beyond age and gender, increasing emphasis is now being given to a variety of demographic and lifestyle variables, including ethnicity, smoking, diet, and exercise, which should be taken into account when interpreting ...

journal_title：Thrombosis research

authors： Lippi G,Favaloro EJ,Franchini M,Guidi GC

更新日期：2008-01-01 00:00:00

abstract：:A validated method for assessing hemostasis in vivo is critical for testing the hemostatic efficacy of therapeutic agents in preclinical animal models and in patients with inherited bleeding disorders, such as von Willebrand disease (VWD) and hemophilia A, or with acquired bleeding disorders such as those resulting fr...

journal_title：Thrombosis research

authors： Scola MR,Baggesen LM,Nichols TC,Key NS,Gallippi CM

更新日期：2012-05-01 00:00:00