当前位置： SCI文献检索 > THROMBOSIS RESEARCH期刊下所有文献 > Identifying the factors influencing practice variation in thrombosis medicine: A qualitative content analysis of published practice-pattern surveys.

Identifying the factors influencing practice variation in thrombosis medicine: A qualitative content analysis of published practice-pattern surveys.

Abstract：

:Practice variation, the differences in clinical management between physicians, is one reason why patient outcomes may differ. Identifying factors that contribute to practice variation in areas of clinical uncertainty or equipoise may have implications for understanding and improving patient care. To discern what factors may influence practice variation, we completed a qualitative content analysis of all practice-pattern surveys in thrombosis medicine in the last 10years. Out of 2117 articles screened using a systematic search strategy, 33 practice-pattern surveys met eligibility criteria. Themes were identified using constant comparative analysis of qualitative data. Practice variation was noted in all 33 practice-pattern surveys. Contributing factors to variation included lack of available evidence, lack of clear and specific guideline recommendations, past experience, patient context, institutional culture and the perceived risk and benefit of a particular treatment. Additional themes highlight the value placed on expertise in challenging clinical scenarios, the complexity of practice variation and the value placed on minimizing practice variation.

journal_name

Thromb Res

journal_title

Thrombosis research

authors

Skeith L,Gonsalves C

doi

10.1016/j.thromres.2017.09.026

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

52-57

eissn

0049-3848

issn

1879-2472

pii

S0049-3848(17)30512-1

journal_volume

159

pub_type

杂志文章

相关文献

THROMBOSIS RESEARCH文献大全
  • Elevated levels of platelet microparticles in carotid atherosclerosis and during the postprandial state.

    abstract：BACKGROUND:Platelet microparticles (PMPs) possess proatherogenic and procoagulant properties which may play a role in atherogenesis and subsequent thromboembolic complications. The present study was conducted to investigate the possible relationship between carotid atherosclerosis and plasma concentrations of PMPs, and...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2008.10.016

    authors： Michelsen AE,Notø AT,Brodin E,Mathiesen EB,Brosstad F,Hansen JB

    更新日期：2009-04-01 00:00:00

  • Clinical and laboratory predictors of deep vein thrombosis after acute stroke.

    abstract：BACKGROUND:Deep vein thrombosis (DVT) is a common complication of acute stroke, but the new incidence in the era of improved specialist input in stroke care is yet unknown. The models for VTE diagnosis is well established, but prediction models to target at-risk patients for pharmacological prophylaxis is lacking and r...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2016.04.002

    authors： Balogun IO,Roberts LN,Patel R,Pathansali R,Kalra L,Arya R

    更新日期：2016-06-01 00:00:00

  • Danazol-induced factor VIII and IX bypassing activity in hemophiliacs.

    abstract：:Danazol, a synthetic androgen reported to increase factor VIII and IX activity levels, was given to 6 hemophiliacs. With danazol therapy (600 mg/da) the APTTs shortened by 30-45% of pre-treatment times. However, the activity levels of the deficient factors did not increase significantly nor consistently with the APTT ...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(85)90126-4

    authors： Garewal HS,Corrigan JJ Jr,Jeter MA,Damiano ML,Durie BG

    更新日期：1985-07-01 00:00:00

  • The Extracellular Matrix Metalloproteinase Inducer (EMMPRIN, CD147) - a potential novel target in atherothrombosis prevention?

    abstract：:The immunoglobulin superfamily member EMMPRIN (CD147) plays an important role in a number of organ systems, including the cardiovascular system. Here we review the contemporary understanding of EMMPRIN and EMMPRIN-associated sequelae in the course of atherosclerosis. A significant body of data documents the pivotal ro...

    journal_title：Thrombosis research

    pub_type： 杂志文章,评审

    doi：10.1016/j.thromres.2013.04.017

    authors： Joghetaei N,Stein A,Byrne RA,Schulz C,King L,May AE,Schmidt R

    更新日期：2013-06-01 00:00:00

  • Fondaparinux versus nadroparin for thromboprophylaxis following minimally invasive esophagectomy: A randomized controlled trial.

    abstract：BACKGROUND:The methodology of thromboprophylaxis post minimally invasive esophagectomy (MIE) is unclear. Thus, we compared the efficacy and safety of fondaparinux and nadroparin on the prophylaxis of venous thromboembolism (VTE) after MIE. MATERIALS AND METHODS:We conducted a randomized, double-blind, treatment-contro...

    journal_title：Thrombosis research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.thromres.2018.04.001

    authors： Song J,Xuan L,Wu W,Shen Y,Tan L,Zhong M

    更新日期：2018-06-01 00:00:00

  • Novel astaxanthin prodrug (CDX-085) attenuates thrombosis in a mouse model.

    abstract：BACKGROUND:Cardiovascular disease remains the leading cause of morbidity and premature mortality in most industrialized countries as well as in developing nations. A pro-oxidative state appears to promote and/or exacerbate vascular disease complications. Furthermore, a state of low-grade chronic inflammation can promot...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2010.07.003

    authors： Khan SK,Malinski T,Mason RP,Kubant R,Jacob RF,Fujioka K,Denstaedt SJ,King TJ,Jackson HL,Hieber AD,Lockwood SF,Goodin TH,Pashkow FJ,Bodary PF

    更新日期：2010-10-01 00:00:00

  • Physiological changes in membrane-expressed platelet factor 4: implications in heparin-induced thrombocytopenia.

    abstract：BACKGROUND:Many heparin-induced thrombocytopenia (HIT) antibodies cause platelet activation in the serotonin release assay (SRA) in the absence of heparin. This in vitro observation may help unravel the mechanism of delayed-onset HIT, where seropositive patients develop thrombocytopenia and associated thrombosis after ...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2009.10.021

    authors： Prechel MM,Jeske WP,Walenga JM

    更新日期：2010-04-01 00:00:00

  • Acquired activated protein C resistance in pregnancy.

    abstract：:Pregnancy induces several haemostatic perturbations. Some authors described possible acquired activated protein C resistance (APCR) during normal pregnancy. We wanted to test this possibility and to evaluate if this acquired APCR might contribute to the known increased tendency to thrombosis associated with pregnancy....

    journal_title：Thrombosis research

    pub_type： 临床试验,杂志文章

    doi：10.1016/0049-3848(96)00177-6

    authors： Schlit AF,Col-De Beys C,Moriau M,Lavenne-Pardonge E

    更新日期：1996-11-01 00:00:00

  • Compartmentation of 4,6-difluoro-5HT studied by nuclear magnetic resonance in normal and CHS bovine platelets.

    abstract：:A platelet storage pool deficiency (SPD) is present in platelets from cattle with the Chediak-Higashi syndrome (CHS). The most plausible hypothesis for the SPD is that dense granule precursors are simply not formed in CHS megakaryocytes. There is, however, evidence that some recently acquired 5-hydroxytryptamine (5HT)...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(90)90096-u

    authors： Meyers KM,Costa JL,Magnuson J

    更新日期：1990-05-01 00:00:00

  • Direct evidence for systemic fibrinogenolysis in a patient with metastatic prostatic cancer.

    abstract：:Although the possible occurrence of systemic fibrinogenolysis has been suggested in patients with metastasising prostatic cancer (MPC), direct evidence is lacking. We report on a patient with MPC whose laboratory data were consistent with hyperfibrinolysis: marked decrease of alpha 2-antiplasmin (AP) level (less than ...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(92)90047-e

    authors： Okajima K,Kohno I,Tsuruta J,Okabe H,Takatsuki K,Binder BR

    更新日期：1992-06-15 00:00:00

  • Echocardiographic evaluation for pulmonary hypertension after recurrent pulmonary embolism.

    abstract：INTRODUCTION:Although recurrent venous thromboembolism is a known risk factor for chronic thromboembolic pulmonary hypertension (CTEPH), the prevalence of CTEPH after recurrent pulmonary embolism (PE) is not clear. MATERIALS AND METHODS:A cohort screening study was performed to clarify the prevalence of echocardiograp...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2011.07.045

    authors： Berghaus TM,Barac M,von Scheidt W,Schwaiblmair M

    更新日期：2011-12-01 00:00:00

  • Optimal INR for prevention of stroke and death in atrial fibrillation: a critical appraisal.

    abstract：INTRODUCTION:Patients with nonvalvular atrial fibrillation are at increased risk for systemic embolism, predominantly disabling stroke. To study how stroke and mortality rates vary with different degrees of anticoagulation reflected by the international normalised ratio (INR) we critically assess information from diffe...

    journal_title：Thrombosis research

    pub_type： 杂志文章,评审

    doi：10.1016/j.thromres.2004.11.025

    authors： Odén A,Fahlén M,Hart RG

    更新日期：2006-01-01 00:00:00

  • Inhibition of activated protein C by aprotinin and the use of the insolubilized inhibitor for its purification.

    abstract：:The study of the interaction between activated protein C (APC) and non-plasmatic inhibitors allowed us to demonstrate that aprotinin is a potent competitive inhibitor of APC with a Ki of 1.35 mumol/L. It was possible to adsorb immunopurified protein C (PC) activated by venom activator to insolubilized aprotinin and to...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(90)90268-h

    authors： Taby O,Chabbat J,Steinbuch M

    更新日期：1990-07-01 00:00:00

  • Collagen derived octapeptide inhibits platelet procoagulant activity induced by the combined action of collagen and thrombin.

    abstract：:Platelet prothrombin converting activity was measured in a system using washed human platelets and purified coagulation factors Xa, Va and prothrombin. Exposure of platelet prothrombin converting activity evoked by collagen or the combined action of collagen and thrombin was effectively inhibited when a collagen deriv...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(85)90065-9

    authors： Bevers EM,Karniguian A,Legrand YJ,Zwaal RF

    更新日期：1985-02-01 00:00:00

  • Effect of freezing method and storage at -20 degrees C and -70 degrees C on prothrombin time, aPTT and plasma fibrinogen levels.

    abstract：:Clinical and epidemiological trials often involve central laboratory analyses of coagulation tests, including fibrinogen, which requires freezing of the plasma samples. Although rapid freezing by immersion of sample tubes in liquid nitrogen and storage at -70 degrees C is recommended, plasma samples are often transfer...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2008.11.010

    authors： Alesci S,Borggrefe M,Dempfle CE

    更新日期：2009-05-01 00:00:00

  • Effect of remote ischaemic conditioning on coagulation function as measured by whole blood impedance aggregometry and rotational thromboelastometry in off-pump coronary artery bypass surgery: A randomised controlled trial.

    abstract：INTRODUCTION:Remote ischaemic conditioning (RIC) has been shown to prevent platelet activation during ablation for atrial fibrillation. RIC has also been associated with more postoperative transfusion in the off-pump coronary artery bypass graft surgery (OPCAB) patients. We evaluated the effects of RIC on coagulation f...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2020.01.004

    authors： Kim TK,Nam K,Cho YJ,Choi S,Row HS,Jeon Y

    更新日期：2020-03-01 00:00:00

  • CYP2C19*2 and other genetic variants affecting platelet response to clopidogrel in patients undergoing percutaneous coronary intervention.

    abstract：INTRODUCTION:Information regarding any possible additional effect of genetic variants other than CYP2C19*2 on platelet reactivity in patients undergoing percutaneous coronary intervention (PCI), while on dual antiplatelet therapy, is sparse. MATERIALS AND METHODS:Genotyping for CYP2C19*2, CYP2C19*17, CYP2C9*3, CYP2B6*...

    journal_title：Thrombosis research

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.thromres.2011.07.022

    authors： Kassimis G,Davlouros P,Xanthopoulou I,Stavrou EF,Athanassiadou A,Alexopoulos D

    更新日期：2012-04-01 00:00:00

  • Lower dosage of recombinant tissue-type plasminogen activator (rt-PA) in the treatment of acute pulmonary embolism: a systematic review and meta-analysis.

    abstract：BACKGROUND AND OBJECTIVE:According to US Food and Drugs Administration (FDA), 2 hour recombinant tissue plasminogen activator (rt-PA) 100mg infusion is recommended for eligible patients with acute pulmonary embolism (PE). However,there exists evidence implying that a lower dosage of rt-PA can be equally effective but p...

    journal_title：Thrombosis research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.thromres.2013.12.026

    authors： Zhang Z,Zhai ZG,Liang LR,Liu FF,Yang YH,Wang C

    更新日期：2014-03-01 00:00:00

  • Relationship between preoperative status of the fibrinolytic system and occurrence of deep vein thrombosis after major abdominal surgery.

    abstract：:This study comprised 50 patients subjected to major abdominal surgery, of which 13 developed deep vein thrombosis (DVT) according to the 125I-fibrinogen test. Plasma was sampled preoperatively, for the specific analysis of tissue plasminogen activator (t-PA) before and during venous occlusion. The recently described f...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(85)90103-3

    authors： Mellbring G,Dahlgren S,Wiman B,Sunnegårdh O

    更新日期：1985-07-15 00:00:00

  • Effect of dietary canola and reference oils upon serum lipids and platelet aggregation.

    abstract：:To compare Canola a terrestrial (n-3) oil with fish oil (n-3) and common vegetable oil (n-6) in decreasing serum lipids and platelet aggregation, various oils were included in Chow-based diets and fed to rats in an eight-weeks feeding trial. The Chow diet contained 2% cholesterol along with either Canola, menhaden, sa...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(90)90420-h

    authors： Watkins T,Lenz P,Bierenbaum M

    更新日期：1990-08-01 00:00:00

  • Statin use and venous thromboembolism in cancer: A large, active comparator, propensity score matched cohort study.

    abstract：BACKGROUND:Statins have been shown to have a protective effect for venous thromboembolism (VTE) in the general population. This study sought to assess the association between statins and the risk for cancer-associated deep vein thrombosis (DVT) and pulmonary embolism (PE). METHODS:Patients with newly diagnosed cancer ...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2017.08.001

    authors： El-Refai SM,Black EP,Adams VR,Talbert JC,Brown JD

    更新日期：2017-10-01 00:00:00

  • Abnormal Ca2+ homeostasis in platelets of patients with myeloproliferative disorders: low levels of Ca2+ influx and efflux across the plasma membrane and increased Ca2+ accumulation into the dense tubular system.

    abstract：:Ca2+ influx and efflux in unstimulated platelets and Ca2+ uptake by simultaneously isolated two membrane fractions of platelets from patients with myeloproliferative disorders (MPD) have been investigated. In MPD, Ca2+ influx and efflux across the plasma membrane in unstimulated platelets were in equilibrium at signif...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(89)90372-1

    authors： Fujimoto T,Fujimura K,Kuramoto A

    更新日期：1989-01-15 00:00:00

  • Fluorescent activity-based probe for the selective detection of Factor VII activating protease (FSAP) in human plasma.

    abstract：:The zymogen form of circulating Factor VII activating protease (FSAP) is activated by histones that are released as a consequence of tissue damage or excessive inflammation. This is likely to have consequences in a number of disease conditions such as stroke, atherosclerosis, liver fibrosis, thrombosis and cancer. To ...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2019.08.016

    authors： Rut W,Nielsen NV,Czarna J,Poreba M,Kanse SM,Drag M

    更新日期：2019-10-01 00:00:00

  • Clinical relevance of pulmonary infarction in patients with pulmonary embolism.

    abstract：INTRODUCTION:Data regarding the clinical relevance of pulmonary infarction (PI) in patients with pulmonary embolism (PE) are lacking. The aim of this study was to investigate the clinical features of PE patients with PI and the prognostic role of PI for PE patients. MATERIALS AND METHODS:Based on computed tomography s...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2012.03.012

    authors： Cha SI,Shin KM,Lee J,Hwangbo Y,Yoo SS,Lee J,Lee SY,Kim CH,Park JY,Jung TH

    更新日期：2012-09-01 00:00:00

  • The molecular localization of the ability of certain monoclonal immunoglobulins to interfere with fibrin polymerization.

    abstract：:When a purified myeloma protein with the ability to inhibit fibrin polymerization was preincubated with sheep anti-human F(ab')2 antibodies, there was a marked reduction of the ability to prolong the thrombin clotting time, while anti-Fc antibodies had only a slight effect. A monoclonal immunoglobulin which shortens t...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(85)90284-1

    authors： Wisløff F,Michaelsen TE,Kierulf P,Godal HC

    更新日期：1985-11-15 00:00:00

  • Genetic and molecular evidence for complement dysregulation in patients with HELLP syndrome.

    abstract：BACKGROUND:HELLP (Hemolysis, elevated liver enzymes and low platelets) syndrome is a severe and acute pregnancy-related disorder that occurs in approximately 2.5 per 1000 deliveries and represents a major cause of maternal and perinatal morbidity and mortality. This syndrome has been suggested to be a microangiopathy a...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2020.08.038

    authors： Bazzan M,Todros T,Tedeschi S,Ardissino G,Cardaropoli S,Stella S,Montaruli B,Marchese C,Roccatello D,Cugno M

    更新日期：2020-12-01 00:00:00

  • Acute vigorous exercise attenuates sensitivity of platelets to nitric oxide.

    abstract：:We tested whether inhibition of platelet activation by nitric oxide (NO) might be altered by strenuous exercise. Sixteen healthy male non-smokers, aged 20-26 years, underwent treadmill testing. All subjects reached Bruce stage IV without chest pain or abnormal ST-T wave changes. Platelet aggregation by Born's method a...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/s0049-3848(97)00162-x

    authors： Sakita S,Kishi Y,Numano F

    更新日期：1997-09-01 00:00:00

  • Elevated lipid peroxide levels in platelets of chronic ischemic heart disease patients.

    abstract：:A significantly higher platelet malondialdehyde-like material (MDA--LM) content after physical and N-ethylmaleimide (NEM) stimulation is found in chronic ischemic heart disease (CHD) patients when compared to the control group. In subjects under aspirin treatment "in vivo" (1 gr/day) no difference is found between CHD...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(82)90305-x

    authors： Valles J,Aznar J,Santos MT,Fernandez MA

    更新日期：1982-09-01 00:00:00

  • The effect of myelin basic protein on the endogenous phosphorylation of platelets.

    abstract：:Bovine myelin basic protein (BP) induced a shape change and endogenous phosphorylation of a 45,000 (45K) molecular weight protein of intact human platelets. This effect occurred rapidly over an effective concentration range of 5-100 microM BP. BP peptides encompassing residues 1-42, 43-88, and 89-169 from the BP molec...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/0049-3848(82)90090-1

    authors： Chiang TM,Whitaker JN,Kang AH,Beachey EH

    更新日期：1982-03-15 00:00:00

  • Ultrastructure and composition of thrombi in coronary and peripheral artery disease: correlations with clinical and laboratory findings.

    abstract：INTRODUCTION:Fibrin structure and cellular composition of thrombi profoundly affect the clinical outcomes in ischemic coronary and peripheral artery disease. Our study addressed the interrelations of structural features of thrombi and routinely measured laboratory parameters. MATERIALS AND METHODS:Thrombi removed by t...

    journal_title：Thrombosis research

    pub_type： 杂志文章

    doi：10.1016/j.thromres.2015.02.004

    authors： Kovács A,Sótonyi P,Nagy AI,Tenekedjiev K,Wohner N,Komorowicz E,Kovács E,Nikolova N,Szabó L,Kovalszky I,Machovich R,Szelid Z,Becker D,Merkely B,Kolev K

    更新日期：2015-04-01 00:00:00