Abstract：
INTRODUCTION:Although recurrent venous thromboembolism is a known risk factor for chronic thromboembolic pulmonary hypertension (CTEPH), the prevalence of CTEPH after recurrent pulmonary embolism (PE) is not clear. MATERIALS AND METHODS:A cohort screening study was performed to clarify the prevalence of echocardiographic variables indicating pulmonary hypertension (PH) in patients after recurrent PE. RESULTS:43 survivors of recurrent PE could be enrolled. Echocardiography indicated likely PH in 7 patients. In 5 out of these 7 patients PH was likely and the left ventricular function was normal. Right heart catheterization and ventilation/perfusion lung scan were performed in these patients. CTEPH could be diagnosed in all 5 patients (11.6% of the total study population). No World Health Organisation functional class (WHO-FC) I patient was suspected to have CTEPH. CTEPH was significantly more often diagnosed in WHO-FC III than in WHO-FC II (33.3% versus 9.5%; p=0.024). CONCLUSIONS:CTEPH was found to be a frequent sequela in patients with recurrent PE. The prevalence of CTEPH is dependent on the patient's functional class. Evaluation for PH might be useful in symptomatic patients after recurrent PE.
journal_name
Thromb Resjournal_title
Thrombosis researchauthors
Berghaus TM,Barac M,von Scheidt W,Schwaiblmair Mdoi
10.1016/j.thromres.2011.07.045subject
Has Abstractpub_date
2011-12-01 00:00:00pages
e144-7issue
6eissn
0049-3848issn
1879-2472pii
S0049-3848(11)00417-8journal_volume
128pub_type
杂志文章abstract：:Low circulating protein C (PC) levels have been observed in sepsis, especially in patients with Neisseriae Meningitides infections. Poor clinical outcome and high limb amputation rates have been associated in infected patients with low circulating PC levels. Published studies using activated PC replacement therapy pat...
journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2014.04.019
更新日期：2014-07-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(82)90308-5
更新日期：1982-09-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(85)90008-8
更新日期：1985-04-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/s0049-3848(02)00306-7
更新日期：2002-09-01 00:00:00
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journal_title：Thrombosis research
pub_type： 临床试验,杂志文章
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更新日期：2012-09-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(83)90181-0
更新日期：1983-06-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(96)00084-9
更新日期：1996-05-15 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2009.09.025
更新日期：2010-03-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(82)90132-3
更新日期：1982-03-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
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更新日期：1985-10-15 00:00:00
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journal_title：Thrombosis research
pub_type： 信件
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更新日期：2019-07-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(84)90233-0
更新日期：1984-08-15 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章,评审
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更新日期：2016-05-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/s0049-3848(00)00234-6
更新日期：2000-08-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章,评审
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更新日期：2015-02-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/S0049-3848(16)30115-3
更新日期：2016-04-01 00:00:00
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pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2009-06-01 00:00:00
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journal_title：Thrombosis research
pub_type： 临床试验,杂志文章
doi：10.1016/s0049-3848(03)00151-8
更新日期：2003-01-25 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2006.12.004
更新日期：2007-01-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(92)90068-l
更新日期：1992-09-15 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2008.02.007
更新日期：2008-01-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2017.11.002
更新日期：2017-12-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/s0049-3848(01)00329-2
更新日期：2001-08-15 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2013.02.008
更新日期：2013-05-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(89)90122-9
更新日期：1989-06-15 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2003.11.008
更新日期：2003-01-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(86)90257-4
更新日期：1986-05-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章,评审
doi：10.1016/j.thromres.2004.06.038
更新日期：2004-01-01 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/0049-3848(87)90299-4
更新日期：1987-04-15 00:00:00
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journal_title：Thrombosis research
pub_type： 杂志文章
doi：10.1016/j.thromres.2017.06.016
更新日期：2017-08-01 00:00:00
