Abstract:
:Salivary gland carcinomas are rare tumors, representing ~0.5% of all malignancies. Myoepithelioma is also uncommon, representing ~1% of all salivary gland tumors. Myoepithelial carcinoma (MC) is even rarer, representing 0.2 to 0.6% of all salivary gland tumors. We herein report a case of MC with multiple metastases arising from a submandibular gland in a 71-year-old male patient and present the associated imaging findings. The patient was considered to have a de novo type of myoepithelial carcinoma, which is reportedly associated with higher malignancy than the transformation type of the disease (i.e., a malignant change from pleomorphic adenoma or myoepithelioma). This was reflected in the multiple lung and bone metastases sites and strong positivity for p53 and Ki-67.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Panelli Santos KCP,Matsuzaki H,Unetsubo T,Tsuyoshi S,Nagatsuka H,Asaumi JIdoi
10.3892/ol.2017.5783subject
Has Abstractpub_date
2017-04-01 00:00:00pages
2679-2683issue
4eissn
1792-1074issn
1792-1082pii
OL-0-0-5783journal_volume
13pub_type
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