Arterial interventional chemotherapy and IMRT with concurrent chemotherapy for nasopharyngeal carcinoma with intracranial involvement.

abstract：:Non-small cell lung cancer (NSCLC) is the leading cause of death in smokers and the most common cause for cancer mortality in both males and females in the United States. Predisposition of this malignancy to distant metastasis leads to poor prognosis; therefore, it is urgent to discover novel therapeutic agents for me...

journal_title：Oncology letters

authors： Zhang Y,Lian J,Wang X

更新日期：2018-03-01 00:00:00

abstract：:Resistance to apoptosis is an characteristic of cancer cells that serves a critical function in tumor development and represents a target for antitumor therapy. Isoimperatorin (ISOIM), a coumarin compound, exhibits antitumor functions in multiple types of tumor cells. However, its antitumor effects and molecular mecha...

journal_title：Oncology letters

authors： Yang HB,Gao HR,Ren YJ,Fang FX,Tian HT,Gao ZJ,Song W,Huang SM,Zhao AF

更新日期：2018-05-01 00:00:00

abstract：:Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors, and has high incidence and mortality rates, worldwide. Myelodysplastic syndrome (MDS), a disorder of hematopoietic stem or progenitor cells, results in marrow failure, which increases the risk of acute myeloid leukemia (AML). Few stu...

journal_title：Oncology letters

authors： Liu L,Liu X,Sun Y,Zeng Y,Tang X,Li X,Liu J,Xiao R

更新日期：2020-11-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a common tumor in south China. Kinesin family member 2A (KIF2A) belongs to the kinesin-13 family and is associated with the growth and invasion of a number of different types of human cancer, including ovarian, breast and prostate cancer. The aim of the present study was to evaluate t...

journal_title：Oncology letters

authors： Zhang Q,Lu D,Liu W,Ye S,Guo H,Liao T,Chen C

更新日期：2019-09-01 00:00:00

abstract：:Bortezomib is approved for treating relapsed multiple myeloma (MM) and mantle cell lymphoma, and clinical evidence has shown complete clinical responses in MM patients. Peripheral neuropathy is one of the most common adverse effects of bortezomib. However, rare evidence has shown that bortezomib is associated with Gui...

journal_title：Oncology letters

authors： Dai X,Sun X,Ni H,Zhu X

更新日期：2015-11-01 00:00:00

abstract：:The present study reports a case of pancreatic vasoactive intestinal peptide-secreting tumor (VIPoma), of 2.2 cm in diameter, arising from the region of the uncus of the pancreas with liver metastases in a 50-year-old patient, which demonstrated unusual multiple-phase spiral computed tomography (MPSCT) results. The pa...

journal_title：Oncology letters

authors： Chen Y,Shi D,Dong F,Han SG,Qian ZH,Yang LI,Wang Y,Yu RS,Li QH,Fu YB

更新日期：2015-10-01 00:00:00

abstract：:Aminoacylase 1 (ACY1) is important for regulating the proliferation of numerous types of cancer. However, the expression and mechanisms underlying the function of ACY1 in colorectal cancer remain unclear. In order to investigate the expression and function of ACY1 in colorectal cancer, tumor tissue and blood samples w...

journal_title：Oncology letters

authors： Yu B,Liu X,Cao X,Zhang M,Chang H

更新日期：2017-04-01 00:00:00

abstract：:A growing body of evidence suggests that oncogenesis is associated with systemic inflammation. The present study investigated white blood cell and platelet indices, whose values change during the inflammatory response, in women with invasive ductal breast carcinoma. Preoperatively obtained white blood cell and platele...

journal_title：Oncology letters

authors： Mantas D,Kostakis ID,Machairas N,Markopoulos C

更新日期：2016-08-01 00:00:00

abstract：:AR-42 is a member of a novelly discovered class of phenylbutyrate-derived histone deacetylase inhibitors, and has a number of antitumor effects in a variety of tumor types; however, the role of AR-42 and its possible mechanisms have not been reported in the treatment of breast cancer. The aim of the present study was ...

journal_title：Oncology letters

authors： Zhou R,Wu J,Tang X,Wei X,Ju C,Zhang F,Sun J,Shuai D,Zhang Z,Liu Q,Lv XB

更新日期：2018-08-01 00:00:00

abstract：:Prostate cancer is the most common form of cancer in men, with increased incidence rates observed in older individuals. Prostate cancer is primarily driven via activation of the androgen receptor (AR), the principal transcriptional factor governing prostate cancer cellular programming and its associated metabolism. On...

journal_title：Oncology letters

authors： Dan C,Zhang H,Zeng W,Huang L,Gong X,Li H,Yang E,Wang L,Yao Q

更新日期：2019-01-01 00:00:00

abstract：:There is increasing evidence that microRNAs (miRNAs) play important roles in tumor progression and development by targeting different genes, including gastric cancer (GC). However, the role of miR-16 in GC is so far unclear. Herein, we examined the function and potential mechanism of miR-16 in GC. Reverse transcriptio...

journal_title：Oncology letters

authors： Jiang X,Wang Z

更新日期：2018-09-01 00:00:00

abstract：:The aim of the present study was to analyze potential therapy targets for prostate cancer using integrated analysis of two gene expression profiles. First, gene expression profiles GSE38241 and GSE3933 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) between prostate can...

journal_title：Oncology letters

authors： Zhao R,Wang Y,Zhang M,Gu X,Wang W,Tan J,Wei X,Jin N

更新日期：2017-11-01 00:00:00

abstract：:Liver X receptors (LXRs) are important members of the nuclear receptor family that were originally determined to function in cholesterol transport and the regulation of immune responses. Synthetic LXR ligands have been developed to treat various diseases including diabetes, Alzheimer's disease and atherosclerosis. Pre...

journal_title：Oncology letters

authors： Ju X,Huang P,Chen M,Wang Q

更新日期：2017-12-01 00:00:00

abstract：:Leptomeningeal metastasis (LM) is an uncommon presentation of relapse in breast cancer, which is associated with poor clinical outcomes and poor prognosis. Notably, LM most commonly occurs in breast cancer. The aim of the present review was to investigate the occurrence of LM as the primary presentation of relapse fol...

journal_title：Oncology letters

authors： Sacco K,Muhammad A,Saleem W,Alshaker H,Monzon L,Islam MR,Pchejetski D

更新日期：2016-08-01 00:00:00

abstract：:The novel synthesis of dibenzofluorene has been achieved by a cyclodehydration method. Several derivatives have also been prepared using this hydrocarbon. These compounds have been tested against a number of cancer cell lines in vitro, and useful selectivity has been observed. ...

journal_title：Oncology letters

authors： Banik BK,Mukhopadhyay C,Becker FF

更新日期：2010-03-01 00:00:00

abstract：:Immunotherapy based on the tumor microenvironment is a feasible method for treating cancer; therefore, it is necessary to investigate the immune microenvironment of pancreatic cancer and the influencing factors of the immune microenvironment. Chemokines are an important factor affecting the tumor immune microenvironme...

journal_title：Oncology letters

authors： Wu B,Wang J,Wang X,Zhu M,Chen F,Shen Y,Zhong Z

更新日期：2020-11-01 00:00:00

abstract：:Despite improvements in diagnosis and treatment, the survival of patients with advanced stages of esophageal squamous cell carcinoma (ESCC) remains poor. Therefore, novel biomarkers that can assist with early detection of ESCC are required. In the present study, three paired ESCC and normal esophageal tissue samples f...

journal_title：Oncology letters

authors： Cheng L,Shi G,Fang C,Li G,Zheng Y,Chen W

更新日期：2019-03-01 00:00:00

abstract：:Damnacanthal, an anthraquinone compound, is isolated from the roots of Morinda citrifolia L. (noni), which has been used for traditional therapy in several chronic diseases, including cancer. Although noni has long been consumed in Asian and Polynesian countries, the molecular mechanisms by which it exerts several ben...

journal_title：Oncology letters

authors： Aziz MY,Omar AR,Subramani T,Yeap SK,Ho WY,Ismail NH,Ahmad S,Alitheen NB

更新日期：2014-05-01 00:00:00

abstract：:Lysine-specific demethylase 1 (LSD1) functions as a transcriptional coregulator by modulating histone methylation and has been associated with numerous high-risk cancers. Previously, our group and others identified LSD1 as an upregulated gene in ovarian cancer, and reported that the upregulation of LSD1 was associated...

journal_title：Oncology letters

authors： Shao G,Wan X,Lai W,Wu C,Jin J,Liu X,Wei Y,Lin Q,Zhang L,Shao Q

更新日期：2018-06-01 00:00:00

abstract：:The aim of the present study was to investigate the feasibility and value of serum microRNAs (miRNAs/miRs) as biological markers for the prediction of the behavior and prognosis of esophageal squamous cell cancer (ESCC). The differential expression of serum miRNA was detected by an miRNA microarray of 9 patients with ...

journal_title：Oncology letters

authors： Hui B,Chen X,Hui L,Xi R,Zhang X

更新日期：2015-11-01 00:00:00

abstract：:Glycocholic acid (GCA) is a novel identified biomarker for hepatocellular carcinoma (HCC). However, clinical pathological study of GCA has not been extensive due to the limited availability of anti-GCA monoclonal antibodies (mAbs) and restricted detection methods. In the present study, using human GCA conjugated with ...

journal_title：Oncology letters

authors： Wu M,Zhai S,Gao J,Wei D,Xue J,Zhou Y,Li N,Hu L

更新日期：2019-03-01 00:00:00

abstract：:Gene therapy with adenoviral early region gene (E1A) may enhance the susceptibility of neoplastic cells to chemotherapy-induced cell death. Our previous study developed a urothelium-specific oncolytic serotype 5 adenovirus (Ad5) with the uroplakin II (UPII) promoter controlling E1A expression. The present study invest...

journal_title：Oncology letters

authors： Li S,Wang F,Zhai Z,Fu S,Lu J,Zhang H,Guo H,Hu X,Li R,Wang Z,Rodriguez R

更新日期：2017-08-01 00:00:00

abstract：:Vestibular schwannoma (VS) is a benign, slow-growing cranial tumor that originates from the hypertrophy of Schwann cells. The majority of sporadic VS are unilateral, and the mechanisms underlying VS tumorigenesis are not fully understood. The human neurofibromin 2 (NF2) gene encodes the tumor suppressor protein merlin...

journal_title：Oncology letters

authors： Su F,Zhou Z,Su W,Wang Z,Wu Q

更新日期：2016-08-01 00:00:00

abstract：:Secretory breast carcinoma is a very rare and distinct subtype of breast cancer, characterized by the presence of intracellular and extracellular secretory material. Secretory breast carcinoma has a good clinical outcome and systemic involvement is rare. The majority of studies of this tumor have been case reports or ...

journal_title：Oncology letters

authors： Lee SG,Jung SP,Lee HY,Kim S,Kim HY,Kim I,Bae JW

更新日期：2014-08-01 00:00:00

abstract：:Plumbagin, a naphthoquinone constituent of Plumbago zeylanica L. (Plumbaginaceae) is widely used in traditional Chinese medicine as an antifungal, antibacterial and anti-inflammatory agent. Plumbagin is known to exhibit proapoptotic, antiangiogenic and antimetastatic effects in cancer cells. The transcriptional co-fac...

journal_title：Oncology letters

authors： Xue YL,Meng XQ,Ma LJ,Yuan Z

更新日期：2016-08-01 00:00:00

abstract：:Circulating tumor cells (CTCs), isolated as a 'liquid biopsy', may provide important diagnostic and prognostic information. Therefore, rapid, reliable and unbiased detection of CTCs are required for routine clinical analyses. It was demonstrated that negative enrichment, an epithelial marker-independent technique for ...

journal_title：Oncology letters

authors： Xu Y,Liu B,Ding F,Zhou X,Tu P,Yu B,He Y,Huang P

更新日期：2017-06-01 00:00:00

abstract：:The present study aimed to investigate the effect of microRNA-150 (miRNA/miR-150) in osteosarcoma (OS) cell invasion and metastasis by the regulation of Ezrin. To compare the differences in the expression of miR-150 and Ezrin, cell models of OS metastasis were established by exogenous transfection of miR-150 on the ba...

journal_title：Oncology letters

authors： Zhan C,Li C,Zhang H,Tang H,Ji F,Qiao SC,Xu WD,Wang ZW

更新日期：2016-11-01 00:00:00

abstract：:Few reports have explored laparoscopic adnexal tumorectomy as a treatment for large and symptomatic ovarian leiomyomas during pregnancy. The current study presents the case of a patient with a large and symptomatic ovarian leiomyoma at 14 weeks of pregnancy. A laparoscopic adnexal tumorectomy was performed without com...

journal_title：Oncology letters

authors： Zhao X,Chen L,Zeng W,Jin B,DU W

更新日期：2014-12-01 00:00:00

abstract：:The aim of the present study was to evaluate the curative effect of fludeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT)-guided intensity-modulated radiotherapy (IMRT) for 42 patients with International Federation of Gynecology and Obstetrics (FIGO) stage III/IV ovarian cancer. Between Jan...

journal_title：Oncology letters

authors： Dang YZ,Li X,Ma YX,Li XL,Yang T,Lu WL,Huang SG

更新日期：2019-01-01 00:00:00

abstract：:Factor that binds to the inducer of short transcripts of the human immunodeficiency virus-1 (FBI-1) represents as a crucial gene regulator in colorectal cancer; however, the correlation between FBI-1 and preoperative radiotherapy (RT) in rectal cancer (RC) has not yet been reported. The aim was to detect FBI-1 express...

journal_title：Oncology letters

authors： Wang CJ,Chao CR,Liu HM,Zhu YY,Adell G,Jarlsfelt I,Zhang H,Sun XF

更新日期：2019-11-01 00:00:00