Photodynamic therapy reduces the inhibitory effect of osteosarcoma cells on dendritic cells by upregulating HSP70.

abstract：:Numerous studies concerning hepatic arterial infusion chemotherapy (HAIC) have been conducted by adopting regimens containing 5-fluorouracil (FU), with a favourable efficacy compared with conventional transcatheter arterial chemoembolisation (TACE) treatment; however, the detailed mechanism of HAIC remains unclear. Th...

journal_title：Oncology letters

authors： Gao J,Zhen R,Liao H,Zhuang W,Guo W

更新日期：2018-05-01 00:00:00

abstract：:The current study reports the case of a large retroperitoneal tumor treated with modified simultaneous integrated boost (SIB) radiotherapy. A 45-year-old female presented to the emergency department complaining of left abdominal pain and fever. A computed tomography scan detected a retroperitoneal tumor of 12×16×16 cm...

journal_title：Oncology letters

authors： Nomiya T,Akamatsu H,Harada M,Ota I,Hagiwara Y,Ichikawa M,Miwa M,Mizutani M,Kato T,Nagaoka A,Tomita Y,Nemoto K

更新日期：2015-06-01 00:00:00

abstract：:Breast metastasis is a rare pattern of distant metastasis from nasopharyngeal carcinoma (NPC) following curative treatment. The present study reported two patients with breast metastasis from NPC and reviewed four such patients reported in the literature, including the analysis of clinical profiles, pathological diagn...

journal_title：Oncology letters

authors： Xiao W,He Z,Xing C,Zhen W,Wang S,Lin H

更新日期：2015-12-01 00:00:00

abstract：:Application of dexmedetomidine combined with sufentanil in colon cancer resection and its effect on immune and coagulation function of patients was studied. Colon cancer cases (n=176) admitted to Xiangya Hospital Central South University were selected into the study. They were divided into group A (n=92) and group B (...

journal_title：Oncology letters

authors： Zhao L,Li Y

更新日期：2020-08-01 00:00:00

abstract：:Vestibular schwannoma (VS) is a benign, slow-growing cranial tumor that originates from the hypertrophy of Schwann cells. The majority of sporadic VS are unilateral, and the mechanisms underlying VS tumorigenesis are not fully understood. The human neurofibromin 2 (NF2) gene encodes the tumor suppressor protein merlin...

journal_title：Oncology letters

authors： Su F,Zhou Z,Su W,Wang Z,Wu Q

更新日期：2016-08-01 00:00:00

abstract：:Ovarian cancer is the most fatal gynecological cancer, with a 5-year survival rate of only 30%. Lysophosphatidic acid (LPA), which possesses growth factor-like functions, is a major regulatory factor in the peritoneal metastasis of ovarian cancer. LPA stimulates the expression of numerous genes that are associated wit...

journal_title：Oncology letters

authors： Wang H,Liu W,Wei D,Hu K,Wu X,Yao Y

更新日期：2014-05-01 00:00:00

abstract：:Ovarian remnant syndrome (ORS) is a rare, but well-known gynecological complication, most often induced by difficult bilateral salpingo-oophorectomy (BSO) procedures that leave residual ovarian tissue on the pelvic wall. The most common preexisting conditions for this complication include endometriosis, pelvic inflamm...

journal_title：Oncology letters

authors： Imai A,Matsunami K,Takagi H,Ichigo S

更新日期：2014-07-01 00:00:00

abstract：:Despite improvements in diagnosis and treatment, the survival of patients with advanced stages of esophageal squamous cell carcinoma (ESCC) remains poor. Therefore, novel biomarkers that can assist with early detection of ESCC are required. In the present study, three paired ESCC and normal esophageal tissue samples f...

journal_title：Oncology letters

authors： Cheng L,Shi G,Fang C,Li G,Zheng Y,Chen W

更新日期：2019-03-01 00:00:00

abstract：:Oncological and functional prognostic factors for patients with foot sarcomas have yet to be clarified. This study was undertaken to identify the prognostic factors for oncological and functional outcomes and the significance of adjuvant radiotherapy in achieving local control in patients with foot sarcomas. We review...

journal_title：Oncology letters

authors： Kozawa E,Nishida Y,Nakashima H,Tsukushi S,Toriyama K,Kamei Y,Ishiguro N

更新日期：2012-01-01 00:00:00

abstract：:Effects of Rapamycin on the proliferation and apoptosis of retinoblastoma cells through the phosphatidylinositol 3-hydroxy kinase (PI3K)/protein kinase B (AKT) signaling pathway were studied. The retinoblastoma Y79 cells were selected and divided into negative control group (NC group), 0.2 µM Rapamycin group and 0.4 µ...

journal_title：Oncology letters

authors： Yao J,Xu M,Liu Z

更新日期：2020-04-01 00:00:00

abstract：:The present study investigated the correlations of the Tspan-1 gene expression with the clinical characteristics and survival prognoses of patients with advanced gastric cancer. A total of 150 patients with advanced gastric cancer were enrolled in the present study, of whom 84 were at stage II and 66 were at stage III...

journal_title：Oncology letters

authors： Cai Y,Zheng M,Zhao Z,Huang H,Fu W,Xu X

更新日期：2017-09-01 00:00:00

abstract：:Expression level of miR-181c in neuroblastoma children and its effect on proliferation of neuroblastoma M17 cells were investigated. Fifty-seven neuroblastoma patients admitted to Weifang People's Hospital from January 2013 to December 2017 were selected and their cancer tissues and normal adjacent tissues were obtain...

journal_title：Oncology letters

authors： Xu X,Wu J,Ren G,Hu Q

更新日期：2019-09-01 00:00:00

abstract：:To assess the influence of microRNA-183 (miR-183) on the migration and invasion of A375 human melanoma cells, an A375 cell line with stable miR-183 overexpression or knockdown was constructed using lentiviral transfection. The change of miR-183 expression in these cells and in non-transfected controls was verified usi...

journal_title：Oncology letters

authors： Zhang Y,Wang G

更新日期：2019-01-01 00:00:00

abstract：:The tumor suppressor protein retinoblastoma protein-interacting zinc finger gene 1 (RIZ1) is downregulated in several types of cancer, including esophageal squamous cell carcinoma (ESCC). The present study used two in vitro methods to re-express RIZ1 in the human ESCC TE13 cell line in order to induce apoptosis. RIZ1 ...

journal_title：Oncology letters

authors： Dong S,Zhang P,Liang S,Wang S,Sun P,Wang Y

更新日期：2013-12-01 00:00:00

abstract：:Ankylosing spondylitis (AS) is a common type of rheumatoid disease, which has recently been demonstrated to be associated with the expression of matrix metalloproteinase (MMP)-2. The aim of the present study was to investigate whether MMP-2 interference reduced the osteogenic differentiation of fibroblasts and to expl...

journal_title：Oncology letters

authors： Yuan B,Wu Z

更新日期：2018-03-01 00:00:00

abstract：:Peritumoral edema (PTE), one of the main characteristics of malignant glioma, is a significant contributor to the morbidity and mortality from glioma, however, a recent systematic review suggested that controversy remains with regard to its prognostic value. To further determine whether PTE was a potential prognostic ...

journal_title：Oncology letters

authors： Wu CX,Lin GS,Lin ZX,Zhang JD,Chen L,Liu SY,Tang WL,Qiu XX,Zhou CF

更新日期：2015-11-01 00:00:00

abstract：:Previous studies have demonstratedf that heat stress can induce injury of the central nervous system and lead to neuronal cell apoptosis. However, the molecular mechanisms underlying these cellular changes remain unclear. In the present study, flow cytometry was used to investigate heat-stress-induced apoptosis, and c...

journal_title：Oncology letters

authors： Li H,Liu Y,Gu Z,Li L,Liu Y,Wang L,Su L

更新日期：2018-01-01 00:00:00

abstract：:This study was designed to explore the expression of phosphoinositide-dependent protein kinase 1 (PDK-1), deleted in malignant brain tumors (DMBT1) in the thyroid carcinoma. A total of 87 fresh samples of thyroid carcinoma from surgical resection in The Second People's Hospital of Lianyungang from June 2016 to March 2...

journal_title：Oncology letters

authors： Sun Z,Xu L

更新日期：2019-09-01 00:00:00

abstract：:Delta-like ligand 4 (Dll4)-Notch signaling is important in tumor angiogenesis; however, the prognostic value of D114 detection in patients with clear cell renal cell carcinoma (CCRCC) remains unclear. The present study aimed to determine whether the presence of high Dll4 expression levels was correlated with poor prog...

journal_title：Oncology letters

authors： Wang W,Yu Y,Wang Y,Li X,Bao J,Wu G,Chang H,Shi T,Yue Z

更新日期：2014-12-01 00:00:00

abstract：:Fatty acid-binding protein 5 (FABP5), which participates in mediating the biological properties of tumor cells, has been recognized in several neoplasms. The present study aims to investigate FABP5 transcriptional expression profiles, reveal its underlying biological interaction networks and define its prognostic valu...

journal_title：Oncology letters

authors： Xu Y,Xu WH,Yang XL,Zhang HL,Zhang XF

更新日期：2020-03-01 00:00:00

abstract：:The present study aimed to investigate the impact of overexpression of long noncoding RNA PEG10 (lncRNA PEG10) on the proliferation, invasion and metastasis of hypopharyngeal squamous cell carcinoma (HSCC). Quantitative reverse transcription polymerase chain reaction was used to quantify lncRNA PEG10 expression levels...

journal_title：Oncology letters

authors： Zhao M,Sun D,Li X,Xu Y,Zhang H,Qin Y,Xia M

更新日期：2017-09-01 00:00:00

abstract：:Regenerating islet-derived family, member 4 (REG4, which encodes Reg IV) is a marker for cancer and inflammatory bowel disease. This study aimed to investigate the diagnostic utility of Reg IV measurement in sera from esophageal cancer patients. Reg IV expression was examined in 269 esophageal cancer samples by immuno...

journal_title：Oncology letters

authors： Oue N,Noguchi T,Anami K,Sentani K,Sakamoto N,Uraoka N,Wakamatsu Y,Sasaki H,Yasui W

更新日期：2011-03-01 00:00:00

abstract：:Breast lumpectomy is usually performed under general or local anesthesia. To the best of our knowledge, whether conscious sedation with intranasal dexmedetomidine and local anesthesia is an effective anesthetic technique has not been studied. Thus, the present study aimed to investigate the effectiveness of conscious ...

journal_title：Oncology letters

authors： Yuan YJ,Zhou P,Xia F,Zhang XB,He SS,Guo DY,Xing YH,Zhao HW

更新日期：2020-10-01 00:00:00

abstract：:Docking protein 2 (Dok2) and Ras p21 protein activator 1 (RASA1) are tumor suppressors which have been identified in numerous solid tumors; however, the association between their expression in breast cancer and patient prognosis remains unclear. A total of 285 consecutive patients diagnosed histopathologically with br...

journal_title：Oncology letters

authors： Huang J,Peng X,Zhang K,Li C,Su B,Zhang Y,Yu W

更新日期：2017-11-01 00:00:00

abstract：:The aim of the present study was to investigate the expression of activin A in esophageal carcinoma and its association with tumor differentiation and metastasis. A total of 57 esophageal carcinoma patients and 36 controls were included in the current study. The mRNA and protein expression levels of activin A in esoph...

journal_title：Oncology letters

authors： Wang Z,Zhang N,Song R,Fan R,Yang L,Wu L

更新日期：2015-07-01 00:00:00

abstract：:This study aims to comparatively analyze the impact of laparoscopic myomectomy (LM) and transcervical resection of myoma (TCRM) on ovarian function, immune function and quality of sexual life of patients with hysteromyoma. Two hundred and forty patients with hysteromyoma admitted into the Second Affiliated Hospital of...

journal_title：Oncology letters

authors： Zhang Y,Gu X,Meng Y,Guo H,Du J,Xing W

更新日期：2018-03-01 00:00:00

abstract：:The present study aimed to investigate the feasibility of using ecto-mesenchymal stem cell (EMSC)-derived dendritic cells (DCs) for glioma immunotherapy following infection by a recombinant adenovirus containing the melanoma-associated antigen D4a (MAGE-D4a) gene. The ex vivo cultured EMSCs were infected by the adenov...

journal_title：Oncology letters

authors： Hu S,Li B,Shen X,Zhang R,Gao D,Guo Q,Jin Y,Fei Z

更新日期：2016-04-01 00:00:00

abstract：:The purpose of this study was to present the results of fertility-sparing treatment using medroxyprogesterone acetate (MPA) for endometrial carcinoma (EC), and to clarify patient characteristics by investigating patient background factors. A total of 59 patients with EC, who received MPA as fertility-sparing therapy a...

journal_title：Oncology letters

authors： Fujiwara H,Jobo T,Takei Y,Saga Y,Imai M,Arai T,Taneichi A,Machida S,Takahashi Y,Suzuki M

更新日期：2012-05-01 00:00:00

abstract：:To aim of the present study was to investigate the association between special AT-rich DNA-binding protein-1 (SATB1) expression and liver cancer metastasis. SATB1 mRNA and protein expression in hepatocellular carcinoma tissues was analyzed by immunohistochemistry, and in two hepatocellular cancer cell lines, MHCC-97H ...

journal_title：Oncology letters

authors： Wu D,Zeng L,Liu F,Zhong Q,Zhang D,Cai C,Zhang W,Wu L,Chen H

更新日期：2016-12-01 00:00:00

abstract：:Skeletal muscle is rich in lymphatic vessels, with an abundant blood supply, and it is an infrequent site of cancer metastasis. Previous studies have demonstrated that enhanced secretion of MyoD may occur when skeletal muscle is injured or becomes cancerous. It was hypothesized that MyoD may act as an endogenous cytok...

journal_title：Oncology letters

authors： Cai C,Qin X,Wu Z,Shen Q,Yang W,Zhang S,Duan J,Liang F,Liu C

更新日期：2016-06-01 00:00:00