Resting-State Functional Connectivity Within Medial Prefrontal Cortex Mediates Age Differences in Risk Taking.

Abstract:

:To investigate the association between age-related changes in risk taking and resting-state functional activity, we recorded resting-state scans from both young (n = 26) and older adults (n = 27). In addition, all participants completed two decision-making tasks: the Cambridge Gambling Task and the Balloon Analogue Risk Task. We found that older adults showed decreased functional connectivity within the medial prefrontal cortex, particularly between the ventromedial prefrontal cortex and the dorsal medial prefrontal cortex. Moreover, these changes in resting-state functional connectivity were associated with the individuals' risk-taking behavior, and mediated the influence of age on risk taking.

journal_name

Dev Neuropsychol

authors

Yu J,Li R,Guo Y,Fang F,Duan S,Lei X

doi

10.1080/87565641.2017.1306529

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

187-197

issue

3

eissn

8756-5641

issn

1532-6942

journal_volume

42

pub_type

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