Melanoma antigen-encoding gene family member A1-6 and hTERT in the detection of circulating tumor cells following CD45- depletion and RNA extraction.

abstract：:MicroRNAs (miRs) are often located in genomic breakpoint regions and are hypothesized to be important regulators involved in the regulation of critical cell processes, including cell apoptosis, proliferation and differentiation. miR-299 has been reported to be upregulated in acute promyelocytic leukemia (APL); however...

journal_title：Oncology letters

authors： Wu SQ,Zhang LH,Huang HB,Li YP,Niu WY,Zhan R

更新日期：2016-07-01 00:00:00

abstract：:In previous studies, we observed that STAT1 and Survivin correlated negatively with gastric cancer tissues, and that the functions of the IFN-γ-STAT1 pathway and Survivin in gastric cancer are the same as those reported for other types of cancer. In this study, the SGC7901 gastric cancer cell line and 83 gastric cance...

journal_title：Oncology letters

authors： Deng H,Zhen H,Fu Z,Huang X,Zhou H,Liu L

更新日期：2012-01-01 00:00:00

abstract：:Nucleobindin 2 (NUCB2) is mainly expressed in the hypothalamic nuclei and has a proven role in energy homeostasis. It has also been recently reported to have a key role in tumor progression. However, the clinical significance of NUCB2 in colorectal cancer (CRC) remains unknown. In the present study, the level of NUCB2...

journal_title：Oncology letters

authors： Xie J,Chen L,Chen W

更新日期：2018-06-01 00:00:00

abstract：:The histological boundary between benign and malignant vascular tumors is not clear. Thus, the discrepancies between clinical judgement and pathological diagnosis often lead to a difficult clinical decision, and may result in misdiagnosis. In order to develop more effective treatment methods, the clinical and patholog...

journal_title：Oncology letters

authors： Li F,Ma L,Zhang L,Zheng L,Lv X,Fu J

更新日期：2013-02-01 00:00:00

abstract：:The purpose of this study was to evaluate the cytotoxic effect of thalidomide on 4T1 and 4THMpc mouse breast cancer cell lines. Mouse breast cancer cells (4T1) and cells derived from metastatic lesions (4THMpc) were treated with various doses of thalidomide [10(-2)-100 µM dissolved in dimethyl sulfoxide (DMSO) as reco...

journal_title：Oncology letters

authors： Oz ES,Aydemir E,Fışkın K

更新日期：2012-04-01 00:00:00

abstract：:The present study aimed to investigate the expression levels and clinical value of miR-365 and miR-25 in serum of patients with non-small cell lung cancer (NSCLC). Patients (180) diagnosed with NSCLC at the Affiliated Hospital of Guangdong Medical University from July 2011 to December 2013 were used as the experimenta...

journal_title：Oncology letters

authors： Huang D,Ou W,Tong H,Peng M,Ou Y,Song Z

更新日期：2020-11-01 00:00:00

abstract：:The present study aimed to investigate the imaging characteristics of primary malignant bone tumors in children. The imaging results of 34 children with primary malignant bone tumors confirmed by histopathological diagnosis between March 2008 and January 2014 were retrospectively analyzed. In total, 25 patients had os...

journal_title：Oncology letters

authors： Sun Y,Liu X,Pan S,Deng C,Li X,Guo Q

更新日期：2017-11-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is a relatively rare low-grade sarcoma that occasionally exhibits melanin-containing spindle cells within the tumor. Fibrosarcomatous DFSP (FS-DFSP) is a variant that is characterized by areas which are histopathologically indistinguishable from fibrosarcoma. In the present study...

journal_title：Oncology letters

authors： Ishida M,Okabe H

更新日期：2012-09-01 00:00:00

abstract：:Epigenetic regulatory mechanisms are a current focus in studies investigating cancer. Chromatin remodeling alters chromatin structure and regulates gene expression, and aberrant chromatin remodeling is involved in carcinogenesis. AT-rich interactive domain-containing protein 1A (ARID1A) and SWItch/sucrose non-fermenta...

journal_title：Oncology letters

authors： Okawa R,Banno K,Iida M,Yanokura M,Takeda T,Iijima M,Kunitomi-Irie H,Nakamura K,Adachi M,Umene K,Nogami Y,Masuda K,Kobayashi Y,Tominaga E,Aoki D

更新日期：2017-11-01 00:00:00

abstract：:A 72-year-old man initially presented with lumbar and right chest pain, but was later found out to also have an elevated prostate-specific antigen (PSA) level at 2,000.0 ng/ml. Further evaluation disclosed metastatic prostate cancer involving the bones and lymph nodes. The patient was initially treated with combined a...

journal_title：Oncology letters

authors： Kato T,Komiya A,Yuasa J,Kaga K,Kaga M,Kojima S,Naya Y,Isaka S

更新日期：2018-02-01 00:00:00

abstract：:Abnormal regulation of long non-coding RNAs (lncRNAs) appears to be a primary feature of numerous types of human cancer. However, the association between the dysregulation of lncRNAs and functional alterations in gastric cancer (GC) remains unclear. In previous studies, we applied microarray and bioinformatics analyse...

journal_title：Oncology letters

authors： Li CY,Liang GY,Yao WZ,Sui J,Shen X,Zhang YQ,Ma SM,Ye YC,Zhang ZY,Zhang WH,Yin LH,Pu YP

更新日期：2018-06-01 00:00:00

abstract：:Lymph node metastasis is the primary site of metastasis for patients with gallbladder cancer (GBC). Vascular endothelial growth factor-C (VEGF-C) has been implicated in the control of lymphangiogenesis and lymph node metastasis in various malignant tumors. However, the function of circulating VEGF-C is unclear and it ...

journal_title：Oncology letters

authors： Jiang L,Liu M,Cai X,Xie L,She F,Chen Y

更新日期：2018-11-01 00:00:00

abstract：:In patients with bladder cancer (BC), the association between ST3 β-galactoside α-2,3-sialyltransferase 5 (ST3GAL5) expression and clinical outcomes, particularly regarding muscle-invasive disease, high tumor grade and prognosis, remain unknown. In the present study, the expression of ST3GAL5 and its association with ...

journal_title：Oncology letters

authors： Ouyang S,Liu JH,Ni Z,Ding GF,Wang QZ

更新日期：2020-07-01 00:00:00

abstract：:Over the latest decade, the role of microRNAs (miRNAs/miRs) has received more attention. miRNAs are small non-coding RNAs that may serve a role as oncogenes or tumor suppressor genes. Certain miRNAs regulate the apoptosis pathway by influencing pro- or anti-apoptotic genes. We hypothesized that increases in the expres...

journal_title：Oncology letters

authors： Ostadrahimi S,Fayaz S,Parvizhamidi M,Abedi-Valugerdi M,Hassan M,Kadivar M,Teimoori-Toolabi L,Asgari M,Shahrokh H,Abolhasani M,Mahdian R,Fard-Esfahani P

更新日期：2018-05-01 00:00:00

abstract：:The aim of the present study was to investigate the association between the clinicopathological and demographic factors, and the survival time of patients with triple-negative breast cancer (TNBC) in China. The patients had received adjuvant chemotherapy consisting of 5-fluorouracil, epirubicin and cyclophosphamide (F...

journal_title：Oncology letters

authors： Sun W,Li C,Liu M,Liu W,Yang C,Cai LI

更新日期：2016-03-01 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (ICC) is an aggressive type of cancer, and its incidence and mortality rates are increasing worldwide. Mortalin is a highly conserved chaperone protein involved in multiple pathological and physiological processes, including anti-apoptosis, carcinogenesis and metastasis. The Bcl-2 famil...

journal_title：Oncology letters

authors： Kang Q,Zou H,Yang X,Cai JB,Liu LX,Xie N,Wang LM,Li YH,Zhang XW

更新日期：2018-02-01 00:00:00

abstract：:Breast cancer is the second leading cause of cancer-associated mortality in females in the USA. Hsa-miR-599 was demonstrated to function as a tumour suppressor during cancer progression. However, the function and mechanism of the hsa-miR-599 in human breast cancer remain elusive. Thus, the aim of the present study was...

journal_title：Oncology letters

authors： Wang Y,Sui Y,Zhu Q,Sui X

更新日期：2017-09-01 00:00:00

abstract：:The aim of the current study was to investigate the effects of resveratrol (Res) on vascular endothelial growth factor (VEGF) expression and cell proliferation in the human osteosarcoma cell line U20S. U20S cells were treated with Res at various concentrations (0, 10, 20 and 40 μmol/l) for various times (24, 48 and 72...

journal_title：Oncology letters

authors： Liu Z,Li Y,Yang R

更新日期：2012-10-01 00:00:00

abstract：:The aim of the present study was to identify the differentially expressed microRNAs (DEMs) between Lynch syndrome (LS) and the normal colonic (N-C) control samples, predict the target genes (TGs) and analyze the potential functions of the DEMs and TGs. The miRNA expression dataset GSE30454, which included data of 13 L...

journal_title：Oncology letters

authors： Zhou C,Li J,Li J,Wan Y,Li T,Ma P,Wang Y,Sang H

更新日期：2016-09-01 00:00:00

abstract：:Isolated cortical vein thrombosis (ICoVT) is a rare form of cerebral venous thrombosis and is easily misdiagnosed as brain tumor due to its atypical clinical presentations and radiological findings similar to brain tumors. The present study focused on 4 patients with ICoVT, 2 men and 2 women. In the 2 male patients, t...

journal_title：Oncology letters

authors： Yu Y,Ren M,Yao S,Zhao X,Qi X

更新日期：2016-01-01 00:00:00

abstract：:Skeletal muscle is rich in lymphatic vessels, with an abundant blood supply, and it is an infrequent site of cancer metastasis. Previous studies have demonstrated that enhanced secretion of MyoD may occur when skeletal muscle is injured or becomes cancerous. It was hypothesized that MyoD may act as an endogenous cytok...

journal_title：Oncology letters

authors： Cai C,Qin X,Wu Z,Shen Q,Yang W,Zhang S,Duan J,Liang F,Liu C

更新日期：2016-06-01 00:00:00

abstract：:The aim of the present study was to investigate the treatment options for patients with tuberous sclerosis complex (TSC)-associated renal angiomyolipomas (AMLs). A total of 17 patients who were consecutively diagnosed with TSC-associated renal AMLs at the Department of Urology of Zhongshan Hospital between 1998 and 20...

journal_title：Oncology letters

authors： Wang H,Long Q,Wang Y,Liu L,Zhou L,Guo J

更新日期：2016-08-01 00:00:00

abstract：:This study was designed to explore the expression of phosphoinositide-dependent protein kinase 1 (PDK-1), deleted in malignant brain tumors (DMBT1) in the thyroid carcinoma. A total of 87 fresh samples of thyroid carcinoma from surgical resection in The Second People's Hospital of Lianyungang from June 2016 to March 2...

journal_title：Oncology letters

authors： Sun Z,Xu L

更新日期：2019-09-01 00:00:00

abstract：:Homoisoflavanone-1 is a natural compound that may be extracted from the Chinese medicinal herb Polygonatum odoratum, which has pronounced antioxidant activities. The present study reports that homoisoflavanone-1 significantly inhibited tumor cell growth and induced apoptosis in A549 non-small cell lung cancer (NSCLC) ...

journal_title：Oncology letters

authors： Ning D,Jin M,Xv T,Sun J,Li M

更新日期：2018-09-01 00:00:00

abstract：:Patients with non-platinum-sensitive recurrent ovarian cancer have a poor prognosis. Non-pegylated liposomal doxorubicin (Myocet®) is a promising drug that may be able to improve treatment for such patients. In the current study, patients with recurrent ovarian cancer relapsing within 12 months after primary treatment...

journal_title：Oncology letters

authors： Brucker J,Mayer C,Gebauer G,Mallmann P,Belau AK,Schneeweiss A,Sohn C,Eichbaum M

更新日期：2016-08-01 00:00:00

abstract：:Cancer and embryo expression protein 65 (CEP65) is a centrosomal protein that is expressed at relatively high levels in embryonic tissue and different cancerous tissues, but its role in tumorigenesis remains unknown. In the present study, CEP65 was stably expressed in AGS gastric cancer cells. CEP65 was found to promo...

journal_title：Oncology letters

authors： Jin G,Peng L,Zhang J,Qu L,Shou C

更新日期：2015-04-01 00:00:00

abstract：:Pulmonary large-cell neuroendocrine carcinoma (LCNEC) is a rare and malignant form of lung cancer with a poor prognosis for patients. The common sites of metastases are the liver, adrenal glands, bone and brain. LCNEC rarely metastasizes to the small intestine, ovaries, tonsils, mandible, vulva or spine. To the best o...

journal_title：Oncology letters

authors： Yang G,Pan Z,Ma N,Qu L,Yuan T,Pang X,Yang X,Dong L,Liu S

更新日期：2017-10-01 00:00:00

abstract：:Current endocrine therapies for females with estrogen receptor-positive breast cancer have facilitated substantial improvements in outcomes. The effectiveness of endocrine therapy is limited by either initial de novo resistance or acquired endocrine resistance. Multiple mechanisms responsible for endocrine resistance ...

journal_title：Oncology letters

authors： Zhou J,Teng R,Wang Q,Xu C,Guo J,Yuan C,Shen J,Hu W,Wang L,Xie S

更新日期：2013-08-01 00:00:00

abstract：:Plumbagin, a naphthoquinone constituent of Plumbago zeylanica L. (Plumbaginaceae) is widely used in traditional Chinese medicine as an antifungal, antibacterial and anti-inflammatory agent. Plumbagin is known to exhibit proapoptotic, antiangiogenic and antimetastatic effects in cancer cells. The transcriptional co-fac...

journal_title：Oncology letters

authors： Xue YL,Meng XQ,Ma LJ,Yuan Z

更新日期：2016-08-01 00:00:00

abstract：:The present study reviewed three patients with acute myeloid leukemia (AML) who had the specific genetic abnormality t(16;21)(p11;q22). To investigate the clinical and laboratory characteristics of AML with t(16;21)(p11;q22) translocation, the similarities and differences of clinical characteristics and laboratory exa...

journal_title：Oncology letters

authors： Zhang Z,Zou J,Li Y,Liu Z,Xu R,Tian W,Zhao Z,Sun H,Han J,Wang J,Zhang B,Ju Y

更新日期：2015-05-01 00:00:00