Comparisons of Efficacy of Intravitreal Aflibercept and Ranibizumab in Eyes with Diabetic Macular Edema.

abstract：:The success rate of oral implants is lower in type 2 diabetes mellitus (T2DM) patients than in nondiabetic subjects; functional impairment of bone marrow-derived mesenchymal stem cells (BMSCs) is an important underlying cause. Many factors in the blood can act on BMSCs to regulate their biological functions and influe...

journal_title：BioMed research international

authors： Liang C,Sun R,Xu Y,Geng W,Li J

更新日期：2020-06-07 00:00:00

abstract：Purpose:3D nonfluoroscopic mapping systems (NMSs) are generally used in the catheter ablation (CA) of complex ventricular and atrial arrhythmias. The aim of this study was to evaluate the efficacy, safety, and long-term effect of the extended, routine use of NMSs for CA. Methods:Our study involved 1028 patients who un...

journal_title：BioMed research international

authors： Marini M,Martin M,Ravanelli D,Del Greco M,Quintarelli S,Guarracini F,Coser A,Valentini A,Bonmassari R

更新日期：2019-03-10 00:00:00

abstract：:Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and drug responses. Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP markers of diseases an...

journal_title：BioMed research international

authors： Ponomarenko P,Rasskazov D,Suslov V,Sharypova E,Savinkova L,Podkolodnaya O,Podkolodny NL,Tverdokhleb NN,Chadaeva I,Ponomarenko M,Kolchanov N

更新日期：2016-01-01 00:00:00

abstract：:Healthcare professionals undergo high levels of occupational stress as a result of their working conditions. Thus, the aim of this study is to develop a model that focuses on healthcare professionals so as to analyze the influence that job demands, control, social support, and recognition have on the likelihood that a...

journal_title：BioMed research international

authors： García-Herrero S,Lopez-Garcia JR,Herrera S,Fontaneda I,Báscones SM,Mariscal MA

更新日期：2017-01-01 00:00:00

abstract：:Human cytoplasmic alpha-fetoprotein (AFP) has been classified as a member of the albuminoid gene family. The protein sequence of AFP has significant homology to that of human serum albumin (HSA), but its biological characteristics are vastly different from HSA. The AFP functions as a regulator in the phosphatidylinosi...

journal_title：BioMed research international

authors： Zhu M,Lin B,Zhou P,Li M

更新日期：2015-01-01 00:00:00

abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

journal_title：BioMed research international

authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

更新日期：2020-09-09 00:00:00

abstract：:Probiotic Lactobacillus casei Shirota (LcS) is a potential decontaminating agent of aflatoxin B1 (AFB1). However, few studies have investigated the influence of diet, especially a high protein (HP) diet, on the binding of AFB1 by probiotics. This research was conducted to determine the effect of HP diet on the ability...

journal_title：BioMed research international

authors： Nurul Adilah Z,Liew WP,Mohd Redzwan S,Amin I

更新日期：2018-05-23 00:00:00

abstract：Background:The chromobox (CBX) proteins CBX2, CBX4, CBX6, CBX7, and CBX8, also known as Polycomb (Pc) proteins, are canonical components of the Polycomb repressive complex 1 (PRC1). Abundant evidence indicates that abnormal expression of Pc proteins is associated with a variety of tumors, but their role in the pathogen...

journal_title：BioMed research international

authors： Tan C,Bei C,Zhu X,Zhang Y,Qin L,Tan S

更新日期：2019-05-09 00:00:00

abstract：:Autoimmunity remains a complex physiologic deviation, enabled and perpetuated by a variety of interplayers and pathways. Simplistic approaches, targeting either isolated end-effectors of more centrally placed interactors of these mechanisms, are continuously tried in an effort to comprehend and halt cascades with pote...

journal_title：BioMed research international

authors： Pateinakis P,Pyrpasopoulou A

更新日期：2014-01-01 00:00:00

abstract：:Nowadays, a growing number of young and more active patients receive hip replacement. More strenuous activities in such patients involve higher friction and wear rates, with friction on the bearing surface being crucial to ensure arthroplasty survival in the long term. Over the last years, the polycarbonate-urethane h...

journal_title：BioMed research international

authors： Gabarre S,Herrera A,Mateo J,Ibarz E,Lobo-Escolar A,Gracia L

更新日期：2014-01-01 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease, where chondrocyte apoptosis is responsible for cartilage degeneration. Bax is a well-known proapoptotic protein of the Bcl-2 family, involved in a large number of physiological and pathological processes. However, the regulation mechanisms of Bax underlying ...

journal_title：BioMed research international

authors： Miao G,Zang X,Hou H,Sun H,Wang L,Zhang T,Tan Y,Liu W,Ye P,Gao L,Zha Z

更新日期：2019-03-12 00:00:00

abstract：:Information and communications technology (ICT) could support ambient assisted living (AAL) based interventions to provide support to informal caregivers of people with dementia, especially when they need to cope with their feelings of overburden or isolation. An e-learning platform (understAID application) was tested...

journal_title：BioMed research international

authors： Núñez-Naveira L,Alonso-Búa B,de Labra C,Gregersen R,Maibom K,Mojs E,Krawczyk-Wasielewska A,Millán-Calenti JC

更新日期：2016-01-01 00:00:00

abstract：:Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking. Autophagy is a cellular process that degrades damaged o...

journal_title：BioMed research international

authors： Song Y,Zhao Y,Wang F,Tao L,Xiao J,Yang C

更新日期：2014-01-01 00:00:00

abstract：Background:A multifactorial decision support system (mDSS) is a tool designed to improve the clinical decision-making process, while using clinical inputs for an individual patient to generate case-specific advice. The study provides an overview of the literature to analyze current available mDSS focused on prostate ca...

journal_title：BioMed research international

authors： van Wijk Y,Halilaj I,van Limbergen E,Walsh S,Lutgens L,Lambin P,Vanneste BGL

更新日期：2019-06-06 00:00:00

abstract：:Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful fo...

journal_title：BioMed research international

authors： Henriquez-Camacho C,Losa J

更新日期：2014-01-01 00:00:00

abstract：Objective:The aim of this study is to explore the potential pathogenesis of juvenile dermatomyositis by bioinformatics analysis of gene chips, which would screen the hub genes, identify potential biomarkers, and reveal the development mechanism of juvenile dermatomyositis. Material and Methods:We retrieved juvenile de...

journal_title：BioMed research international

authors： Qiu CC,Su QS,Zhu SY,Liu RC

更新日期：2019-12-07 00:00:00

abstract：:Tsetse flies (Glossina spp.) are the primary vectors of trypanosomes, which can cause human and animal African trypanosomiasis in Sub-Saharan African countries. The objective of this study was to explore the genome of Glossina morsitans morsitans for evidence of horizontal gene transfer (HGT) from microorganisms. We e...

journal_title：BioMed research international

authors： Nakao R,Abe T,Funayama S,Sugimoto C

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Noninvasive tools to diagnose nonalcoholic fatty liver disease (NAFLD), including transient elastography (TE) and enhanced liver fibrosis panel (ELF), have only been evaluated in children with biopsy-proven NAFLD. We evaluated the prevalence of ELF and TE abnormalities in obese children without clinical live...

journal_title：BioMed research international

authors： Goldschmidt I,Di Nanni A,Streckenbach C,Schnell K,Danne T,Baumann U

更新日期：2015-01-01 00:00:00

abstract：Background:This study explored the therapeutic efficacy of standard triple therapy combined with sucralfate suspension gel as well as the mechanisms of action in mouse models of H. pylori infection. Materials and Methods:C57BL/6J mice were randomly divided into 5 groups: NC (natural control), HP (H. pylori infection),...

journal_title：BioMed research international

authors： Teng G,Liu Y,Wu T,Wang W,Wang H,Hu F

更新日期：2020-08-31 00:00:00

abstract：:In spite of the declining incidence of gastric cancer (GC) in recent years, the mortality rate is still high. The asymptomatic nature and nonspecific clinical manifestations combined with the lack of efficient screening programs delay the diagnosis of GC. Therefore, the prevalence of advanced gastric cancer (AGC) has ...

journal_title：BioMed research international

authors： Xu W,Beeharry MK,Liu W,Yan M,Zhu Z

更新日期：2016-01-01 00:00:00

abstract：:Dengue fever, a reemerging disease, is putting nearly 2.5 billion people at risk worldwide. The number of infections and the geographic extension of dengue fever infection have increased in the past decade. The disease is caused by the dengue virus, a flavivirus that uses mosquitos Aedes sp. as vectors. The disease ha...

journal_title：BioMed research international

authors： De La Guardia C,Lleonart R

更新日期：2014-01-01 00:00:00

abstract：:This study investigated the role of gender as a potential predictor of health behaviour and potential moderator of the relationship between emotional intelligence and health behaviour. This cross-sectional study included 1214 students (597 males and 617 females). Data were collected using the Schutte Self-Report Inven...

journal_title：BioMed research international

authors： Malinauskas R,Dumciene A,Sipaviciene S,Malinauskiene V

更新日期：2018-06-04 00:00:00

abstract：:In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially limited to Th1 and T...

journal_title：BioMed research international

authors： Ivanova EA,Orekhov AN

更新日期：2015-01-01 00:00:00

abstract：:Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can b...

journal_title：BioMed research international

authors： Kang J,Fan W,Deng Q,He H,Huang F

更新日期：2019-01-29 00:00:00

abstract：Background:The aim of this article is to present a short review of noninvasive, nonpharmacological treatment methods used in somatic illnesses that fall under the umbrella of approach called behavioral medicine. Methods:The narrative review method was applied in the study. Science paper databases, including PubMed, ha...

journal_title：BioMed research international

authors： Białkowska J,Juranek J,Wojtkiewicz J

更新日期：2020-11-03 00:00:00

abstract：:Taking into account that there are controversial antioxidative effects of inhalational anesthetics isoflurane and sevoflurane and absence of comparison of genotoxicity of both anesthetics in animal model, the aim of this study was to compare DNA damage and antioxidant status in Wistar rats exposed to a single time to ...

journal_title：BioMed research international

authors： Rocha TL,Dias-Junior CA,Possomato-Vieira JS,Gonçalves-Rizzi VH,Nogueira FR,de Souza KM,Braz LG,Braz MG

更新日期：2015-01-01 00:00:00

abstract：:Natural plant extracts contain a variety of phenolic compounds which are assigned various biological activities. Our work aims to make a quantitative and qualitative characterization of the Zest (ZL) and the Flesh (FL) of lemon (Citrus limon), to valorize the pharmacological uses of lemon, by evaluating in vitro activ...

journal_title：BioMed research international

authors： Makni M,Jemai R,Kriaa W,Chtourou Y,Fetoui H

更新日期：2018-01-15 00:00:00

abstract：:We evaluated single nucleotide polymorphism (SNP) detection via a target-capture, C-probe ligation, and RAM assay in a single-blind comparison to clinical samples that had been tested with FDA-cleared tests for up to 4 different vascular disease-related SNPs. In the RAM assay circulizable linear probes (C- or padlock ...

journal_title：BioMed research international

authors： Smith JH,Cui M,Zhang DY,Beals TP,Ye F

更新日期：2014-01-01 00:00:00

abstract：:Estimation of the spread and advancement of Plasmodium falciparum artemisinin-resistant parasites can be done by probing polymorphisms in the kelch (Pfk13) domain (a validated molecular marker). This study aimed to provide baseline information for future artemisinin surveillance by analyzing the k13-propeller domain i...

journal_title：BioMed research international

authors： Rana R,Ranjit M,Bal M,Khuntia HK,Pati S,Krishna S,Das A

更新日期：2020-03-15 00:00:00

abstract：:Alterations in muscle protein turnover of the unaffected side of stroke patients could contribute to physical disability. We investigated whether hypercatabolic activity occurred in unaffected arm muscle and whether supplemented essential amino acids (EAAs) could limit muscle hypercatabolism (MH). Thirty-eight dysphag...

journal_title：BioMed research international

authors： Aquilani R,Boselli M,D'Antona G,Baiardi P,Boschi F,Viglio S,Iadarola P,Pasini E,Barbieri A,Dossena M,Bongiorno AI,Verri M

更新日期：2014-01-01 00:00:00