Abstract:
:Adult neuronal cells which can regenerate have been reported. The present study investigated whether acupuncture enhances neuronal regeneration in ischemic stroke rats. We established an ischemic stroke rat model by occluding the cerebral blood flow of the right middle cerebral artery for 15 minutes and then allowing reperfusion in Sprague-Dawley rats. The results indicated that, in these rats, 2 Hz electroacupuncture (EA) at both Zusanli (ST36) and Shangjuxu (ST37) acupoints reduced the infarction/hemisphere ratio 8 days after reperfusion and reduced the modified neurological severity score (mNSS) and increased the rotarod test time 4 and 8 days after reperfusion, respectively. In addition, 2 Hz reduced nestin immunoreactive cells in the penumbra area and the ischemic core area; 2 Hz EA also reduced Ki67 immunoreactive cells and increased glial fibrillary acidic protein immunoreactive cells in the penumbra area. These findings suggest that 2 Hz EA at the ST36 and ST37 acupoints has a neuroprotective role. However, additional studies are needed to further investigate these preliminary results.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Liao SL,Lin YW,Hsieh CLdoi
10.1155/2017/3178014subject
Has Abstractpub_date
2017-01-01 00:00:00pages
3178014eissn
2314-6133issn
2314-6141journal_volume
2017pub_type
杂志文章abstract:BACKGROUND:This study aimed to analyze differences in necrotic changes between cortical and cancellous bone in resection margins after segmental mandibulectomy for advanced mandibular osteoradionecrosis. METHODS:Anteroposterior bone specimens from eleven patients who underwent segmental mandibulectomy with simultaneou...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/3125842
更新日期:2017-01-01 00:00:00
abstract::Accurate definition and better understanding of the mechanisms of stroke are crucial as this will guide the effective care and therapy. In this paper, we review the previous basic and clinical researches on the causes or mechanisms of ischemic cerebrovascular diseases (ICVD) and interpret the correlation between embol...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2016/8531958
更新日期:2016-01-01 00:00:00
abstract:Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5046934
更新日期:2019-06-23 00:00:00
abstract:Introduction:The purpose of this study was to investigate the difference in surgical outcomes between symptomatic and asymptomatic patients with primary hyperparathyroidism (PHPT) and between patients with high serum calcium and those with normal blood calcium, as well as to explore the epidemiological trend of PHPT in...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2019/2150159
更新日期:2019-07-01 00:00:00
abstract::Enteric fever caused by Salmonella enterica is a life-threatening systemic illness of gastrointestinal tract especially in tropical countries. Antimicrobial therapy is generally indicated but resistance towards commonly used antibiotics has limited their therapeutic usefulness. Therefore, we aimed to determine the ant...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2868143
更新日期:2017-01-01 00:00:00
abstract::Diabetic patients are at risk for spontaneous foot ulcers, chronic wounds, infections, and tissue necrosis. Current theories suggest that the development and progression of diabetic foot ulcers are mainly caused by arteriosclerosis and peripheral neuropathy. Tissue necrosis plays a primordial role in the progression o...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/490964
更新日期:2013-01-01 00:00:00
abstract::Somatostatin (SST) receptors (SSTRs) belong to the typical 7-transmembrane domain family of G-protein-coupled receptors. Five distinct subtypes (termed SSTR1-5) have been identified, with SSTR2 showing the highest affinity for natural SST and synthetic SST analogs. Most neuroendocrine tumors (NETs) have high expressio...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/917968
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:We investigated the integron types and their relation with antibiotic resistance among A. baumannii isolates collected from intensive care unit patients, Babol, north of Iran. METHODS:In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibili...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/7157923
更新日期:2017-01-01 00:00:00
abstract::Although the application of patient-specific instruments (PSI) for total knee arthroplasty (TKA) increases the cost of the surgical procedure, PSI may reduce operative time and improve implant alignment, which could reduce the number of revision surgeries. We report our experience with TKA using PSI techniques in 120 ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/978686
更新日期:2015-01-01 00:00:00
abstract::Osteocalcin (Ocn) and testosterone play important roles in male skeleton. However, the concentrations of serum osteocalcin and testosterone have never been systematically compared between populations with and without primary male osteoporosis, a common skeletal disorder in adult males. We searched the PubMed, Embase, ...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2017/9892048
更新日期:2017-01-01 00:00:00
abstract::Purpose. We examined the role of miR-20b in development of thymoma-associated myasthenia gravis, especially in T cell proliferation and activation. Materials and Methods. Using qRT-PCR, we assessed expression levels of miR-20b and its target genes in cultured cells and patient samples and examined the proliferation of...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/9595718
更新日期:2016-01-01 00:00:00
abstract::Epithelial Cl(-) secretion plays important roles in water secretion preventing bacterial/viral infection and regulation of body fluid. We previously suggested that quercetin would be a useful compound for maintaining epithelial Cl(-) secretion at a moderate level irrespective of cAMP-induced stimulation. However, we n...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/902735
更新日期:2014-01-01 00:00:00
abstract::Lung cancer is one of the most malignant tumors in the world. Early diagnosis and treatment of lung cancer are vitally important to reduce the mortality of lung cancer patients. In the present study, we attempt to identify the candidate biomarkers for lung cancer by weighted gene co-expression network analysis (WGCNA)...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/3416807
更新日期:2020-06-10 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/575079
更新日期:2015-01-01 00:00:00
abstract:Background:The purpose of this study was to evaluate the association between the non-high-density lipoprotein cholesterol (non-HDL-C) to high-density lipoprotein cholesterol (HDL-C) ratio and the risk of coronary artery disease (CAD). We also explored the potential role of non-HDL-C/HDL-C in the prognosis of CAD. Meth...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/7146028
更新日期:2020-03-07 00:00:00
abstract::In consequence of the key role of factor Xa in the clotting cascade and absence of its activity in the processes that do not affect coagulation, this protein is an attractive target for development of new blood coagulation inhibitors. Factor Xa is more effective and convenient target for creation of anticoagulants tha...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/120802
更新日期:2015-01-01 00:00:00
abstract::Professional phagocytic cells, such as dendritic cells, are mainly responsible for phagocytosis, antigen presentation, and cytokine secretion, which induce subsequent activation of T cell-mediated immunity. Thus, strategies that deliver antigens and stimulatory signals to the cells have significant implications for va...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/562924
更新日期:2013-01-01 00:00:00
abstract:Background:Currently, effective genetic markers are limited to predict the clinical outcome of melanoma. High-throughput multiomics sequencing data have provided a valuable approach for the identification of genes associated with cancer prognosis. Method:The multidimensional data of melanoma patients, including clinic...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5323614
更新日期:2020-05-08 00:00:00
abstract::Over the last years, a number of therapeutic strategies have emerged to promote axonal regeneration. An attractive strategy is the implantation of biodegradable and nonimmunogenic artificial scaffolds into injured peripheral nerves. In previous studies, transplantation of decellularized veins filled with spider silk f...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/906819
更新日期:2014-01-01 00:00:00
abstract::In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially limited to Th1 and T...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/327470
更新日期:2015-01-01 00:00:00
abstract:Methods:The implantation sites, fetus resorption, and abnormal fetuses were studied in pregnant mice treated with different doses of BaP by oral gavage from day 1 to day 10 of gestation. Additionally, apoptosis and related signaling pathway, and the migration and invasion of trophoblasts, were assessed before and after...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8983494
更新日期:2020-10-16 00:00:00
abstract::This study aimed to examine the expression of and the relationship between CD44V6, CDH11, and β-catenin. The expression of these cell adhesion molecules was detected in 90 osteosarcoma and 20 osteochondroma specimens using immunohistochemistry. Associations between these parameters and clinicopathological data were al...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/496193
更新日期:2013-01-01 00:00:00
abstract::The Purkinje network is a specialized conduction system within the heart that ensures the proper activation of the ventricles to produce effective contraction. Its role during ventricular arrhythmias is less clear, but some experimental studies have suggested that the Purkinje network may significantly affect the gene...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/621034
更新日期:2015-01-01 00:00:00
abstract::Despite the rapid progression of cancer pharmacotherapy, the high drug resistance of pancreatic ductal adenocarcinoma (PDA) makes it one of the most lethal malignancies. Therefore, there are high expectations associated with experimental therapies, such as electrochemotherapy (ECT). This technique involves the applica...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/7364539
更新日期:2018-03-19 00:00:00
abstract:Aims:To investigate demographics and socioeconomic status in patients with ulnar nerve compression and the influence of socioeconomic factors on patient-reported outcome measurements (PROM) as evaluated by QuickDASH (short version of Disabilities of Arm, Shoulder and Hand) after surgery for ulnar nerve compression at t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5928649
更新日期:2020-12-18 00:00:00
abstract::Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the present study, antiproliferative potential of gedunin was evaluated in human embryonal carcinoma cells (NTERA-2, a cancer stem cell model) and peripheral blood mononuclear cells (PBMCs), using Sulforhodamine (SRB) and WST-1 assay...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2413197
更新日期:2017-01-01 00:00:00
abstract::Here we wanted to investigate predictive value of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in the diagnosis of brucellosis. Thirty-two brucellosis patients diagnosed with positive serum agglutination test and thirty-two randomized healthy subjects were enrolled in this study retrospectivel...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/210502
更新日期:2015-01-01 00:00:00
abstract::Saponins are a group of naturally occurring plant glycosides with the features of their strong foam-forming properties and multibiological effects such as antitumor activity. Though Misaponin B, one of the triterpenoid saponins from Madhuca longifolia, is known to have spermicidal and antioxidant activity, the other b...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5925094
更新日期:2020-02-07 00:00:00
abstract:Objective:To compare the effectiveness of arthroscopic partial meniscectomy (APM) and physical therapy (PT) for degenerative meniscus tears. Method:We conducted a literature search through PubMed, Embase, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov. Randomized controlled trials in adults...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2020/1709415
更新日期:2020-03-03 00:00:00
abstract::Translocations are the most common type of structural chromosomal abnormalities. Unbalanced translocations are usually found in children who present with congenital abnormalities, developmental delay, or intellectual disability. Balanced translocations are usually found in adults who frequently present with reproducti...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9797104
更新日期:2019-04-02 00:00:00