Magnifying Endoscopy with Blue Laser Imaging Improves the Microstructure Visualization in Early Gastric Cancer: Comparison of Magnifying Endoscopy with Narrow-Band Imaging.

Abstract:

BACKGROUNDS:Magnifying endoscopy with blue laser imaging (ME-BLI) for diagnosis of early gastric cancer (EGC) is as effective as magnifying endoscopy with narrow-band imaging (ME-NBI). However, there are different EGCs in microstructure visualization between ME-BLI and ME-NBI. This study aimed to clarify the pathological features of the EGCs, in which microstructure visualization was different between ME-NBI and ME-BLI. METHODS:EGCs were classified into groups A (irregular microsurface pattern (MSP) in ME-BLI and absent MSP in ME-NBI), B (irregular MSP in two modalities), or C (absent MSP in two modalities), according to the vessel plus surface classification. We compared the pathological features of EGCs between the three groups. RESULTS:17, four, and five lesions could be evaluated in detail in groups A, B and C, respectively. Well-differentiated adenocarcinomas with shallow crypts were more frequent in group A than in group B (58.8 and 0%, resp.). The mean crypt depth of group A was significantly shallower than that of group B (56 ± 20, 265 ± 64 μm, resp., P = 0.0002). CONCLUSIONS:ME-BLI could better visualize the microstructures of the EGCs with shallow crypts compared with ME-NBI. Therefore, ME-BLI could enable a more accurate diagnosis of EGC with shallow crypts.

authors

Kimura-Tsuchiya R,Dohi O,Fujita Y,Yagi N,Majima A,Horii Y,Kitaichi T,Onozawa Y,Suzuki K,Tomie A,Okayama T,Yoshida N,Kamada K,Katada K,Uchiyama K,Ishikawa T,Takagi T,Handa O,Konishi H,Kishimoto M,Naito Y,Yanagisa

doi

10.1155/2017/8303046

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

8303046

eissn

1687-6121

issn

1687-630X

journal_volume

2017

pub_type

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