Beneficial Effects of Probiotic Treatment on Gut Microbiota in Very Low Birth Weight Infants.

Abstract:

:The very low birth weight (VLBW) infant is at great risk for marked dysbiosis of the gut microbiota. In the present study, a total of 36 VLBW infants were randomly divided into two groups, who were treated with combined probiotics and placebo, and 72 fecal specimens on days 14 and 28 of life were collected from them. Finally, 32 fecal specimens extracted from 16 preterm VLBW infants were qualified and analyzed using 16S rRNA gene sequencing. The primary outcome was to evaluate the change of gut microbiota in VLBW infants after combined probiotic supplement. The secondary outcome was to analyze the correlation gut microbial composition and levels of cytokines. We found that probiotic treatment, but not placebo, decreased the α-diversity of gut microbiota in VLBW infants. At the phylum level, probiotic treatment strongly increased the abundance of Firmicutes, whereas that of Proteobacteria was significantly reduced. At the family level, Streptococcaceae and Lactobacillaceae became prevalent after probiotic treatment, while the relative abundance of Enterobacteriaceae was reduced in the meantime. Most notably, significant correlations were observed between Lactobacillaceae abundance and serum cytokine levels. Further studies are required to shed more light on the characteristics of gut microbiota of VLBW neonates. And the modulation of microbiota should be considered to improve the survival rate of VLBW infants.

authors

Li YF,Zhu CR,Gong XL,Li HL,Xiong LK,Wang KJ,Liu GS

doi

10.1155/2019/3682836

subject

Has Abstract

pub_date

2019-10-17 00:00:00

pages

3682836

eissn

1687-6121

issn

1687-630X

journal_volume

2019

pub_type

杂志文章
  • Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease.

    abstract::Activation of innate immunity is associated with the development of liver disease, including non-alcoholic fatty liver disease (NAFLD). In the innate immune system, Toll-like receptors (TLRs) are sensors that recognize bacterial and viral components such as lipopolysaccharide, bacterial DNA, and peptidoglycan. Recent ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2010/362847

    authors: Miura K,Seki E,Ohnishi H,Brenner DA

    更新日期:2010-01-01 00:00:00

  • 2017 Update on Ovarian Cancer Peritoneal Carcinomatosis Multimodal-Treatment Considerations.

    abstract::Ovarian cancer peritoneal carcinomatosis requires a multimodal-treatment approach. Current treatment considerations are analyzed in this update and include the management of recurrent malignant ascites and the understanding of its pathophysiology, the role of peritoneal washing cytology in detecting peritoneal metasta...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2018/5284814

    authors: Halkia E,Chrelias G,Chrelias C,Esquivel J

    更新日期:2018-04-05 00:00:00

  • Prognostic Significance of Microvessel Density Determining by Endoglin in Stage II Rectal Carcinoma: A Retrospective Analysis.

    abstract::Background. The role of endoglin in the Dukes B rectal cancer is still unexplored. The aim of this study was to examine the expression of endoglin (CD105) in resected rectal cancer and to evaluate the relationship between microvessels density (MVD), clinicopathological factors, and survival rates. Methods. The study i...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2015/504179

    authors: Martinovic Z,Kovac D,Martinovic M

    更新日期:2015-01-01 00:00:00

  • Experience with Balloon Dilatation in Crohn's and Non-Crohn's Benign Small-Bowel Strictures: Is There a Difference?

    abstract:Background/Aim:Endoscopic balloon dilation (EBD) has been effective for small-bowel strictures in patients with Crohn's disease (CD). However, its efficacy and indication for small-bowel strictures in non-CD patients have not been established. This study evaluated the clinical efficacy and safety of EBD for small-bowel...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2019/1262595

    authors: Tsuboi A,Oka S,Tanaka S,Iio S,Otani I,Kunihara S,Hayashi R,Chayama K

    更新日期:2019-05-06 00:00:00

  • Aberrant MicroRNAs in Pancreatic Cancer: Researches and Clinical Implications.

    abstract::Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high rate of mortality and poor prognosis. Numerous studies have proved that microRNA (miRNA) may play a vital role in a wide range of malignancies, including PDAC, and dysregulated miRNAs, including circulating miRNAs, are associated with PDAC...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2014/386561

    authors: Sun T,Kong X,Du Y,Li Z

    更新日期:2014-01-01 00:00:00

  • Differentiating Branch Duct and Mixed IPMN in Endoscopically Collected Pancreatic Cyst Fluid via Cytokine Analysis.

    abstract::Background. Differentiating branch duct from mixed intraductal papillary mucinous neoplasm (BD-IPMN) is problematic, but clinically important as mixed IPMNs are managed surgically, while some BD-IPMN may be followed. Inflammatory mediator proteins (IMPs) have been implicated in acute and chronic inflammatory and malig...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/247309

    authors: Lee LS,Bellizzi AM,Banks PA,Sainani NI,Kadiyala V,Suleiman S,Conwell DL,Paulo JA

    更新日期:2012-01-01 00:00:00

  • Association of eNOS Gene Polymorphisms G894T and T-786C with Risk of Hepatorenal Syndrome.

    abstract::Background. There are no studies investigating the relationship between endothelial nitric oxide synthase (eNOS) gene polymorphisms and hepatorenal syndrome (HRS). Aim. The purpose of this study is to elucidate whether eNOS gene polymorphisms (G894T and T-786C) play a role in the development of type-2 HRS. Methods. Th...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/2579626

    authors: Seckin Y,Yigit A,Yesilada E,Gulbay G,Cagin YF,Gozukara H,Bılgıc Y,Yildirim O,Turkoz Y,Aksungur Z

    更新日期:2016-01-01 00:00:00

  • Psychological issues in inflammatory bowel disease: an overview.

    abstract::Inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC) is a chronic and disabling disease with unknown etiology. There have been some controversies regarding the role of psychological factors in the course of IBD. The purpose of this paper is to review that role. First the evidence...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/106502

    authors: Sajadinejad MS,Asgari K,Molavi H,Kalantari M,Adibi P

    更新日期:2012-01-01 00:00:00

  • Does Extending the Waiting Time of Low-Rectal Cancer Surgery after Neoadjuvant Chemoradiation Increase the Perioperative Complications?

    abstract::Background. Traditionally, rectal cancer surgery is recommended 6 to 8 weeks after completing neoadjuvant chemoradiation. Extending the waiting time may increase the tumor response rate. However, the perioperative complication rate may increase. The purpose of this study was to determine the association between extend...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/7870815

    authors: Timudom K,Phothong N,Akaraviputh T,Chinswangwatanakul V,Pongpaibul A,Petsuksiri J,Ithimakin S,Trakarnsanga A

    更新日期:2016-01-01 00:00:00

  • Perioperative nutrition in abdominal surgery: recommendations and reality.

    abstract::Introduction. Preoperative malnutrition is a major risk factor for increased postoperative morbidity and mortality. Definition and diagnosis of malnutrition and its treatment is still subject for controversy. Furthermore, practical implementation of nutrition-related guidelines is unknown. Methods. A review of the ava...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2011/739347

    authors: Cerantola Y,Grass F,Cristaudi A,Demartines N,Schäfer M,Hübner M

    更新日期:2011-01-01 00:00:00

  • Chewing Gum for Intestinal Function Recovery after Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis.

    abstract:Background:This meta-analysis was performed to assess the efficacy and safety of chewing gum in intestinal function recovery after colorectal cancer surgery. Methods:A systematic search was conducted in PubMed, Embase, Science Direct, and Cochrane library for relevant randomized controlled trials (RCTs) published unti...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2017/3087904

    authors: Mei B,Wang W,Cui F,Wen Z,Shen M

    更新日期:2017-01-01 00:00:00

  • Thread-Traction with a Sheath of Polypectomy Snare Facilitates Endoscopic Submucosal Dissection of Early Gastric Cancers.

    abstract::Although the thread-traction (TT) method has been found useful during endoscopic submucosal dissection (ESD) for early gastric cancers, the movement of the thread interferes with the movement of the endoscope, and the lesion can only be pulled to the mouth side. We have developed the novel TT method using a sheath of ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/9415497

    authors: Noda H,Ogasawara N,Koshino A,Fukuta S,Nagoya T,Hoshino H,Nagao K,Sugiyama T,Kondo Y,Ito Y,Izawa S,Ebi M,Funaki Y,Sasaki M,Kasugai K

    更新日期:2016-01-01 00:00:00

  • Efficacy of 7-Day and 14-Day Triple Therapy Regimens for the Eradication of Helicobacter pylori: A Comparative Study in a Cohort of Romanian Patients.

    abstract::Objective. This study compared the eradication rates of of Helicobacter pylori (HP) infection by a 7-day and 14-day anti-HP regimen. Materials and Methods. An open, randomized, prospective study was performed to evaluate the response to anti-HP treatment in adult HP-positive patients following a 7-day course (Regimen ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/5061640

    authors: Arama SS,Tiliscan C,Negoita C,Croitoru A,Arama V,Mihai CM,Pop F,Garg A

    更新日期:2016-01-01 00:00:00

  • Hepatitis B virus-related glomerulonephritis: not a predominant cause of proteinuria in korean patients with chronic hepatitis B.

    abstract::Background/Aims. Hepatitis B virus (HBV) can form immune complexes which may result in various types of glomerulonephritis (GN). However, proteinuria can occur because of other kidney diseases besides HBV-related GN (HBV-GN). The aim of this study is to elucidate the causes of proteinuria and report on the clinical ou...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2015/126532

    authors: Yoo JJ,Lee JH,Yoon JH,Lee M,Lee DH,Cho Y,Jang ES,Cho EJ,Yu SJ,Kim YJ,Lee HS

    更新日期:2015-01-01 00:00:00

  • Bifidobacterium animalis ssp. lactis 420 Protects against Indomethacin-Induced Gastric Permeability in Rats.

    abstract::Gastrointestinal (GI) adverse effects such as erosion and increased permeability are common during the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Our objective was to assess whether Bifidobacterium animalis ssp. lactis 420 protects against NSAID-induced GI side effects in a rat model. A total of 120 male Wi...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/615051

    authors: Lyra A,Saarinen M,Putaala H,Olli K,Lahtinen SJ,Ouwehand AC,Madetoja M,Tiihonen K

    更新日期:2012-01-01 00:00:00

  • The application of functional magnetic resonance imaging in an infant rat model of irritable bowel syndrome.

    abstract::The aim of this study was to use functional magnetic resonance imaging (BOLD-fMRI) to investigate the activated region associated with visceral pain in the brains of infant rats in a model of IBS. Sixteen newborn rats were randomized into an IBS model group and a control group. Those in the IBS group were separated fr...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2014/473846

    authors: Zhu X,Zhu X,Chen W,Chen J

    更新日期:2014-01-01 00:00:00

  • Risk Factors for Mortality in Patients with Aortoesophageal Fistula Related to Aortic Lesions.

    abstract:Objective:Aortoesophageal fistula (AEF) related to aortic aneurysm and dissection is an uncommon but life-threatening condition. We performed a systematic review of risk factors for mortality and factors associated with the prognosis of AEF. Methods:A systematic search of the PubMed, Embase, and Cochrane Library datab...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2020/4850287

    authors: Li S,Gao F,Hu HO,Shi J,Zhang J

    更新日期:2020-09-17 00:00:00

  • Recent Advances in NSAIDs-Induced Enteropathy Therapeutics: New Options, New Challenges.

    abstract::The injurious effects of NSAIDs on the small intestine were not fully appreciated until the widespread use of capsule endoscopy. It is estimated that over two-thirds of regular NSAID users develop injury in the small intestinal injuries and that these injuries are more common than gastroduodenal mucosal injuries. Rece...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2013/761060

    authors: Lim YJ,Chun HJ

    更新日期:2013-01-01 00:00:00

  • Polyglycolic Acid Felt Sealing Method for Prevention of Bleeding Related to Endoscopic Submucosal Dissection in Patients Taking Antithrombotic Agents.

    abstract::Background and Study Aims. When performing endoscopic submucosal dissection (ESD) for patients on antithrombotic agents, the frequency of delayed bleeding is expected to increase. The endoscopic polyglycolic acid (PGA) felt and fibrin glue sealing method could be a new method for prevention of delayed bleeding. Patien...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2016/1457357

    authors: Fukuda H,Yamaguchi N,Isomoto H,Matsushima K,Minami H,Akazawa Y,Ohnita K,Takeshima F,Shikuwa S,Nakao K

    更新日期:2016-01-01 00:00:00

  • ABO incompatible liver transplantation as a bridge to treat HELLP syndrome.

    abstract::The following is a case report of a primiparous woman who developed fulminant liver failure in the setting of HELLP syndrome complicated by hepatic rupture. It is unique in that a timely ABO compatible liver donor was unavailable, necessitating the transplantation of an ABO incompatible organ. Despite aggressive thera...

    journal_title:Gastroenterology research and practice

    pub_type:

    doi:10.1155/2009/713937

    authors: Connor K,Rubin RA,Shrestha R,Johnson M,Sellers M,Butler B

    更新日期:2009-01-01 00:00:00

  • Usefulness of Routine Terminal Ileoscopy and Biopsy during Colonoscopy in a Tropical Setting: A Retrospective Record-Based Study.

    abstract::Introduction. Available evidence for routine terminal ileoscopy during colonoscopy is equivocal. We investigated the place of routine terminal ileoscopy and biopsy during colonoscopy, in a tropical setting. Materials and Methods. All consenting adults undergoing colonoscopy had routine TI and biopsy. Patients with rig...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2014/343849

    authors: Wijewantha HS,de Silva AP,Niriella MA,Wijesinghe N,Waraketiya P,Kumarasena RS,Dassanayake AS,Hewawisenthi Jde S,de Silva HJ

    更新日期:2014-01-01 00:00:00

  • Small intestinal tumours.

    abstract::Objective. Balloon enteroscopy (BE) and capsule enteroscopy (CE) are enteroscopy methods that allow examination and treatment of the small bowel. Before the CE and BE era, the small intestine was difficult to access for investigation. Small intestinal tumours are infrequent conditions, but about half of them are malig...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2013/702536

    authors: Kopáčová M,Rejchrt S,Bureš J,Tachecí I

    更新日期:2013-01-01 00:00:00

  • Colonic Gastrointestinal Stromal Tumor: A Population-Based Analysis of Incidence and Survival.

    abstract:Objectives:The incidence of gastrointestinal stromal tumors (GISTs) located in the colon is rare. Current studies mainly focus on case reports for colonic GISTs. Therefore, a population-based analysis was useful to guide the clinical treatment strategy. Methods:The patients were selected from 2000 to 2015 based on Sur...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2019/3849850

    authors: Liu Z,Sun Y,Li Y,Zhao J,Wu S,Meng Z,Wu H

    更新日期:2019-04-11 00:00:00

  • The Efficacy and Safety of Elobixibat for the Elderly with Chronic Constipation: A Multicenter Retrospective Cohort Study.

    abstract:Materials and Methods:This was a multicenter retrospective cohort study. The subjects were patients aged ≥20 years treated for chronic constipation from May 2018 to November 2019 at 12 related institutions. Patients were divided into ≤74 years and ≥75 years old. Elobixibat at 10 mg/day was prescribed for two weeks. We ...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2020/9656040

    authors: Tomie A,Yoshida N,Kugai M,Hirose R,Dohi O,Inoue K,Okuda K,Motoyoshi T,Fukumoto K,Inagaki Y,Yoriki H,Inada Y,Okuda T,Hasegawa D,Ogiso K,Murakami T,Soga K,Rani RA,Yoshida N,Itoh Y

    更新日期:2020-04-28 00:00:00

  • An Indole Alkaloid Extracted from Evodia rutaecarpa Inhibits Colonic Motility of Rats In Vitro.

    abstract::Evodiamine (Evo) is an indole alkaloid extracted from the traditional Chinese medicinal herb Evodia rutaecarpa. Evo may regulate gastrointestinal motility, but the evidence is insufficient, and the mechanisms remain unknown. The aim of this study was to investigate the effect of Evo on colonic motility of rats and the...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2020/8610653

    authors: Wang GX,Xiang YL,Wang HG,Miu YD,Yu G

    更新日期:2020-04-03 00:00:00

  • Balloon-Assisted Enteroscopy for Retrieval of Small Intestinal Foreign Bodies: A KASID Multicenter Study.

    abstract:Background and Aims:Balloon-assisted enteroscopy (BAE) can be used to retrieve small intestinal foreign bodies (FBs). Here, we aimed at exploring the clinical usefulness of BAE for the retrieval of small intestinal FBs. Methods:We retrospectively reviewed the medical records of 34 patients who underwent BAE to retriev...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2020/3814267

    authors: Kim J,Lee BJ,Ham NS,Oh EH,Choi KD,Ye BD,Byeon JS,Eun CS,Kim JS,Yang DH

    更新日期:2020-05-19 00:00:00

  • Probiotics and Alcoholic Liver Disease: Treatment and Potential Mechanisms.

    abstract::Despite extensive research, alcohol remains one of the most common causes of liver disease in the United States. Alcoholic liver disease (ALD) encompasses a broad spectrum of disorders, including steatosis, steatohepatitis, and cirrhosis. Although many agents and approaches have been tested in patients with ALD and in...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章,评审

    doi:10.1155/2016/5491465

    authors: Li F,Duan K,Wang C,McClain C,Feng W

    更新日期:2016-01-01 00:00:00

  • Subthreshold Psychiatric Psychopathology in Functional Gastrointestinal Disorders: Can It Be the Bridge between Gastroenterology and Psychiatry?

    abstract:Background and Aims:Functional gastrointestinal disorders (FGDs) are multifactorial disorders of the gut-brain interaction. This study investigated the prevalence of Axis I and spectrum disorders in patients with FGD and established the link between FGDs and psychopathological dimensions. Methods:A total of 135 consec...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2017/1953435

    authors: Stasi C,Nisita C,Cortopassi S,Corretti G,Gambaccini D,De Bortoli N,Fani B,Simonetti N,Ricchiuti A,Dell'Osso L,Marchi S,Bellini M

    更新日期:2017-01-01 00:00:00

  • The Spectrum of Endoscopic Ultrasound Intervention in Biliary Diseases: A Single Center's Experience in 31 Cases.

    abstract::Background and Aim. EUS-guided intervention (EGI) for biliary therapy has been increasingly used in recent years. This report aims to describe the spectrum and experience of EUS-guided interventions in biliary diseases in a single-tertiary center. Methods. All patients with EGI were analyzed retrospectively by retriev...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/680753

    authors: Attasaranya S,Netinasunton N,Jongboonyanuparp T,Sottisuporn J,Witeerungrot T,Pirathvisuth T,Ovartlarnporn B

    更新日期:2012-01-01 00:00:00

  • Psychopharmacological treatment and psychological interventions in irritable bowel syndrome.

    abstract::Irritable bowel syndrome (IBS) accounts for 25% of gastroenterology output practice, making it one of the most common disorders in this practice. Psychological and social factors may affect the development of this chronic disorder. Furthermore, psychiatric symptoms and psychiatric diseases are highly prevalent in this...

    journal_title:Gastroenterology research and practice

    pub_type: 杂志文章

    doi:10.1155/2012/486067

    authors: Sinagra E,Romano C,Cottone M

    更新日期:2012-01-01 00:00:00