Abstract:
Background/Aim:Endoscopic balloon dilation (EBD) has been effective for small-bowel strictures in patients with Crohn's disease (CD). However, its efficacy and indication for small-bowel strictures in non-CD patients have not been established. This study evaluated the clinical efficacy and safety of EBD for small-bowel strictures in non-CD patients compared with CD patients. Methods:Ninety-eight consecutive patients (mean age, 53 years; average observation period, 45 months) with small-bowel strictures diagnosed by double-balloon endoscopy were retrospectively evaluated at Hiroshima University Hospital from August 2003 to April 2017. The average number of procedures, short-term and long-term EBD success rates, and safety profiles between the non-CD and CD groups were examined. Results:Surgery was selected as the initial treatment in 44 cases (45%) (non-CD group, 27 (61%); CD group, 17 (39%)) as EBD is not indicated. Fourteen non-CD patients had strictures due to malignant tumors, while 13 patients had benign strictures. Twenty-three patients (non-CD, 12; CD, 11) underwent EBD. Forty-three EBD procedures were performed for 17 stricture sites (average: 2.5 procedures/site) in non-CD patients and 41 EBD procedures for 18 stricture sites (average: 2.3 procedures/site) in CD patients. The short-term success rate was 100% (23/23), whereas the long-term success rate was 92% (11/12) in non-CD patients and 82% (9/11) in CD patients. No significant differences in the surgery-free rate occurred between both groups. Furthermore, one adverse event, bleeding after EBD, was encountered in the non-CD group (8%, 1/12). Conclusion:EBD for small-bowel strictures demonstrated good clinical outcomes in non-CD patients.
journal_name
Gastroenterol Res Practjournal_title
Gastroenterology research and practiceauthors
Tsuboi A,Oka S,Tanaka S,Iio S,Otani I,Kunihara S,Hayashi R,Chayama Kdoi
10.1155/2019/1262595subject
Has Abstractpub_date
2019-05-06 00:00:00pages
1262595eissn
1687-6121issn
1687-630Xjournal_volume
2019pub_type
杂志文章abstract::Background and Aim. EUS-guided intervention (EGI) for biliary therapy has been increasingly used in recent years. This report aims to describe the spectrum and experience of EUS-guided interventions in biliary diseases in a single-tertiary center. Methods. All patients with EGI were analyzed retrospectively by retriev...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/680753
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Preoperative chemoradiotherapy is the standard treatment for patients with locally advanced rectal cancer, although tumor responses vary widely; some patients may achieve a pathologic complete response rate (pCR) after chemoradiotherapy. Controversy exists with regard to the efficacy of different preoperativ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2017/1373092
更新日期:2017-01-01 00:00:00
abstract::Aim. Chronic gastritis was assessed serologically, endoscopically and histologically to identify correlations between these methods. Methods. Subjects comprised 319 patients who had provided informed consent. Serological assessment of chronic gastritis was based on the pepsinogen test method. Endoscopic gastritis and ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2011/631461
更新日期:2011-01-01 00:00:00
abstract::Gastric ectopic pancreas is an uncommon developmental anomaly and its histological diagnosis is usually difficult by using a conventional biopsy forceps. In the literature, most cases of gastric ectopic pancreas were usually diagnosed by gross pattern during endoscopic examination or features of endoscopic ultrasound....
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/160601
更新日期:2014-01-01 00:00:00
abstract:Background:We conducted this meta-analysis to compare the efficacy and safety of simultaneous hepatectomy and splenectomy (HS) with hepatectomy alone (HA) in patients with hepatocellular carcinoma (HCC) and hypersplenism. Materials and Methods:A systematic search was conducted in PubMed, Embase, Cochrane Library, and ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2019/9065845
更新日期:2019-08-14 00:00:00
abstract::Background. There has been an increasing interest in the use of volatile organic compounds (VOCs) as potential surrogate markers of gut dysbiosis in gastrointestinal disease. Gut dysbiosis occurs when pathological imbalances in gut bacterial colonies precipitate disease and has been linked to the dysmetabolism of bile...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2015/398585
更新日期:2015-01-01 00:00:00
abstract::Primary biliary cirrhosis (PBC) is a chronic cholestatic liver condition characterized by the immune-mediated damage of the intrahepatic bile ducts. Polymorphisms of vitamin D receptor (VDR) are considered to contribute to its pathogenesis however their incidence varies in different populations and their potential ass...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/408723
更新日期:2012-01-01 00:00:00
abstract:Objectives:The aims of this study were to evaluate the C-reactive protein/albumin ratio (CRP/ALB), inflammatory markers, and parameters from the complete blood count (CBC) in patients with inflammatory bowel disease (IBD) and their associations with disease activity. Methods:A total of 876 IBD patients, composed of 27...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/3467419
更新日期:2020-06-22 00:00:00
abstract:Objective:Fucosterol is derived from the brown alga Eisenia bicyclis and has various biological activities, including antioxidant, anticancer, and antidiabetic properties. The aim of this study was to investigate the protective effects of fucosterol pretreatment on Concanavalin A- (ConA-) induced acute liver injury in ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/2824139
更新日期:2018-07-17 00:00:00
abstract::Confocal laser endomicroscopy (CLE) is one of several novel methods that provide real-time, high-resolution imaging at a micronscale via endoscopes. CLE and related technologies are often termed "virtual biopsy" as they simulate the images seen in traditional histology. Recently, the use of CLE was reported in the stu...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/525098
更新日期:2012-01-01 00:00:00
abstract::Reorganization of the actin cytoskeleton underlies cell migration in a wide variety of physiological and pathological processes, such as embryonic development, wound healing, and tumor cell invasion. It has been shown that actin assembly and disassembly are precisely regulated by intracellular signaling cascades that ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2015/930157
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:A relationship between intestinal motility and ileostomy prolapse has been suggested but not demonstrated objectively. AIMS:This study evaluated the association between ileostomy prolapse and intestinal dysmotility in children. METHODS:IRB-approved retrospective review of 163 patients with ileostomies (199...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/7182429
更新日期:2017-01-01 00:00:00
abstract:Materials and Methods:This was a multicenter retrospective cohort study. The subjects were patients aged ≥20 years treated for chronic constipation from May 2018 to November 2019 at 12 related institutions. Patients were divided into ≤74 years and ≥75 years old. Elobixibat at 10 mg/day was prescribed for two weeks. We ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/9656040
更新日期:2020-04-28 00:00:00
abstract:Background and Aim:As part of the EC-IBD prospective inception cohort study, we had unique opportunity to follow up our patients since diagnosis in the early 1990s. Patients and Methods:All patients from the greater Dublin area (n = 192) were followed up from inception between 1991 and 1993 until the 30 September 2009...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/4946068
更新日期:2017-01-01 00:00:00
abstract::Background. An increasing resistance of Helicobacter pylori strains to antimicrobial agents is the serious therapeutic problem. The aim of this study was to compare the primary and secondary resistance of H. pylori strains isolated between 2006-2008 (data published) and 2009-2011 to clarithromycin and levofloxacin. Ma...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/418010
更新日期:2012-01-01 00:00:00
abstract::Evodiamine (Evo) is an indole alkaloid extracted from the traditional Chinese medicinal herb Evodia rutaecarpa. Evo may regulate gastrointestinal motility, but the evidence is insufficient, and the mechanisms remain unknown. The aim of this study was to investigate the effect of Evo on colonic motility of rats and the...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/8610653
更新日期:2020-04-03 00:00:00
abstract::Objective. Role of dysfunction of the sphincter of Oddi (SO) in choledocholithiasis is controversial. This study was to evaluate SO motor activity in patients with common bile duct (CBD) stones in the Han population of China. Patients and Methods. In this study, 76 patients with CBD stones were enrolled in a single te...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/9031438
更新日期:2017-01-01 00:00:00
abstract::The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endos...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2018/7823182
更新日期:2018-07-26 00:00:00
abstract::Background. Surgical treatment of hydatid liver disease (HLD) is divided into conservative and radical procedures. While conservative techniques are easier and faster to perform, there is an emerging need to reduce their morbidity and recurrence rates. Our aim was to present and evaluate the efficiency and safety of t...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/1078653
更新日期:2016-01-01 00:00:00
abstract::Alterations in gut microbiota are postulated to be an etiologic factor in the pathogenesis of irritable bowel syndrome (IBS). To determine whether IBS patients in China exhibited differences in their gut microbial composition, fecal samples were collected from diarrhea-predominant IBS (IBS-D) and healthy controls and ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/6961783
更新日期:2018-06-05 00:00:00
abstract::Background. Since the incidence of adenocarcinoma of the oesophagus is rising, the prognosis is poor, and surveillance programs are expensive and mostly cost ineffective, there is a need to increase the knowledge of risk factors in Barrett's oesophagus and oesophageal cancer in order to be able to give attention to me...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/408470
更新日期:2014-01-01 00:00:00
abstract::Background. Transanal irrigation (TAI) can successfully treat neurogenic bowel dysfunction (NBD), but patient perception of its use in chronic idiopathic constipation (CIC) is unknown. Objective. To evaluate patient perceptions of the efficacy and safety of TAI for CIC and whether there are predictive factors of perce...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/3826087
更新日期:2017-01-01 00:00:00
abstract::Previous studies have shown the high diagnostic accuracy of narrow-band imaging magnifying endoscopy (NBI-ME) and Lugol chromoendoscopy with pink-color sign assessment (LCE-PS) for superficial esophageal squamous cell carcinoma (SESCC). However, there has been no controlled trial comparing these two diagnostic techniq...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/639462
更新日期:2015-01-01 00:00:00
abstract:Background:Tumor regression grade (TRG) is widely used in gastrointestinal carcinoma to evaluate pathological responses to neoadjuvant chemotherapy (NCT), but whether it is an independent prognostic factor is still controversial. The aim of this study is to investigate the value of TRG in locally advanced gastric adeno...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/3435673
更新日期:2020-07-18 00:00:00
abstract::Objective. To establish a standardized animal model for liver fibrosis with the same assessment criteria for liver fibrosis studies that have been established on a unified platform. Methods. The standardized liver fibrosis model was established using Sprague-Dawley (SD) rats that either received an intraperitoneal inj...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/560345
更新日期:2012-01-01 00:00:00
abstract::Objective. We aimed to determine the effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) in patients with inoperable perihilar cholangiocarcinoma and establish the incidence of cholangitis development following ERCP. Material and Method. This retrospective study enrolled patients diagnosed with inop...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/508286
更新日期:2014-01-01 00:00:00
abstract::Background. Endoscopic-Ultrasonography- (EUS-) guided puncture and drainage of pancreatic pseudocyst is currently one of the most widely accepted nonsurgical treatments. To date, this technique has only been used for pancreatic pseudocysts adhesive to the gastric wall. This study introduces the technique of EUS-guided...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2013/785483
更新日期:2013-01-01 00:00:00
abstract::Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postcon...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/2604032
更新日期:2016-01-01 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high rate of mortality and poor prognosis. Numerous studies have proved that microRNA (miRNA) may play a vital role in a wide range of malignancies, including PDAC, and dysregulated miRNAs, including circulating miRNAs, are associated with PDAC...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2014/386561
更新日期:2014-01-01 00:00:00
abstract::We explain the state of the art of the immunohistochemical markers of response in rectal cancers treated with neoadjuvant medical therapies and its implication with prognosis. Neoadjuvant chemoradiotherapy is widely used to improve the outcome of patients with locally advanced rectal cancer, and the evaluation of the ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2017/2808235
更新日期:2017-01-01 00:00:00