Impact of Body Mass Index on Surgical and Oncological Outcomes in Laparoscopic Total Mesorectal Excision for Locally Advanced Rectal Cancer after Neoadjuvant 5-Fluorouracil-Based Chemoradiotherapy.

abstract：:Background. Apoptotic rates in peripheral blood lymphocytes can predict radiation induced normal tissue toxicity. We studied whether apoptosis in lymphocytes has a prognostic value for therapy outcome. Methods. Lymphocytes of 87 rectal cancer patients were ex vivo irradiated with 2 Gy, 8 Gy, or a combination of 2 Gy i...

journal_title：Gastroenterology research and practice

authors： Winkler S,Hoppe P,Haderlein M,Hecht M,Fietkau R,Distel LV

更新日期：2016-01-01 00:00:00

abstract：:The incidence of inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), has increased in pediatric populations over the last decade. Patients diagnosed during childhood often survive well into adulthood, and therefore their healthcare requires transfer to an adult gastroenterolo...

journal_title：Gastroenterology research and practice

authors： Bollegala N,Nguyen GC

更新日期：2015-01-01 00:00:00

abstract：:Obesity is nowadays a public health problem both in the industrialized world and developing countries. The different treatments to fight against obesity are not very successful with the exception of gastric surgery. The mechanism behind the achievement of this procedure remains unclear although the modifications in th...

journal_title：Gastroenterology research and practice

authors： Barja-Fernández S,Folgueira C,Castelao C,Leis R,Casanueva FF,Seoane LM

更新日期：2015-01-01 00:00:00

abstract：:Achieving optimal weight outcomes for patients with obesity is important to the management of their chronic disease. All interventions present risks for weight regain. Bariatric surgery is the most efficacious treatment, producing greater weight losses that are sustained over more time compared to lifestyle interventi...

journal_title：Gastroenterology research and practice

authors： Johnson Stoklossa C,Atwal S

更新日期：2013-01-01 00:00:00

abstract：:Hilar cholangiocarcinoma (HCCA) involves a complex anatomical region where bile ducts, arteries, and veins create a complex network. HCCA can lead to biliary strictures at the main hepatic confluence, involving the right and left radicles. Endoscopic drainage of jaundiced patients with HCCA is challenging and carries ...

journal_title：Gastroenterology research and practice

authors： Tringali A,Boškoski I,Costamagna G

更新日期：2019-11-04 00:00:00

abstract：:Objective. We aimed to determine the effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) in patients with inoperable perihilar cholangiocarcinoma and establish the incidence of cholangitis development following ERCP. Material and Method. This retrospective study enrolled patients diagnosed with inop...

journal_title：Gastroenterology research and practice

authors： Ipek S,Alper E,Cekic C,Cerrah S,Arabul M,Aslan F,Unsal B

更新日期：2014-01-01 00:00:00

abstract：:Purpose. In the present study, the prognostic significance of CpG island methylator phenotype (CIMP) in stage II/III sporadic colorectal cancer was evaluated using a five-gene panel. Methods. Fifty stage II/III colorectal cancer patients who received radical resection were included in this study. Promoter methylation ...

journal_title：Gastroenterology research and practice

authors： Wang Y,Long Y,Xu Y,Guan Z,Lian P,Peng J,Cai S,Cai G

更新日期：2014-01-01 00:00:00

abstract：:Background. Here we aimed to evaluate and compare the efficacy and safety between partial full-thickness myotomy and circular muscle myotomy during POEM procedure in achalasia patients. Methods. Clinical data of achalasia of cardia (AC) patients who underwent POEM in our center during January 2014 to January 2015 was ...

journal_title：Gastroenterology research and practice

authors： Li C,Gong A,Zhang J,Duan Z,Ge L,Xia N,Leng J,Li M,Liu Y

更新日期：2017-01-01 00:00:00

abstract：:Due to the call for fast KRAS mutation status analysis for treatment of patients with monoclonal antibodies for metastatic colorectal cancer, sensitive, economic, and easily feasible methods are required. Under this aspect, the sensitivity and specificity of the SNaPshot analysis in comparison to the commonly used DNA...

journal_title：Gastroenterology research and practice

authors： Zinsky R,Bölükbas S,Bartsch H,Schirren J,Fisseler-Eckhoff A

更新日期：2010-01-01 00:00:00

abstract：:Autophagy is a catabolic process by which a cell degrades its intracellular materials to replenish itself. Induction of autophagy under various cellular stress stimuli can lead to either cell survival or cell death via apoptotic and/or autophagic (nonapoptotic) pathways. The NSAID sulindac sulfide induces apoptosis in...

journal_title：Gastroenterology research and practice

authors： Chiou SK,Hoa N,Ge L,Jadus MR

更新日期：2012-01-01 00:00:00

abstract：Background:The da Vinci robotic system was considered an effectively alternative treatment option for early gastric cancer patients in recent years. The aim of our study was to evaluate the safety and feasibility of robot-assisted gastrectomy in our center. Methods:This study included 33 patients who underwent robot-a...

journal_title：Gastroenterology research and practice

authors： Sun LF,Liu K,Su XS,Wei X,Chen XL,Zhang WH,Chen XZ,Yang K,Zhou ZG,Hu JK

更新日期：2019-10-23 00:00:00

abstract：:Hepatocellular carcinoma (HCC) ranks second amongst all causes of cancer deaths globally. It is on a rise in Pakistan and might represent the most common cancer in adult males. Pakistan contributes significantly to global burden of hepatitis C, which is a known risk factor for HCC, and has one of the highest prevalenc...

journal_title：Gastroenterology research and practice

authors： Hafeez Bhatti AB,Dar FS,Waheed A,Shafique K,Sultan F,Shah NH

更新日期：2016-01-01 00:00:00

abstract：:Toll-like receptor (TLR) signaling pathways are strictly coordinated by several mechanisms to regulate adequate innate immune responses. Recent lines of evidence indicate that the suppressor of cytokine signaling (SOCS) family proteins, originally identified as negative-feedback regulators in cytokine signaling, are i...

journal_title：Gastroenterology research and practice

authors： Fujimoto M,Naka T

更新日期：2010-01-01 00:00:00

abstract：:Evodiamine (Evo) is an indole alkaloid extracted from the traditional Chinese medicinal herb Evodia rutaecarpa. Evo may regulate gastrointestinal motility, but the evidence is insufficient, and the mechanisms remain unknown. The aim of this study was to investigate the effect of Evo on colonic motility of rats and the...

journal_title：Gastroenterology research and practice

authors： Wang GX,Xiang YL,Wang HG,Miu YD,Yu G

更新日期：2020-04-03 00:00:00

abstract：Background:Nonselective β-blockers (NSBB) have been associated with increased incidence of paracentesis-induced circulatory dysfunction (PICD) and reduced survival in patients with cirrhosis and refractory ascites. Aim:To prospectively evaluate a hemodynamic response to NSBB in cirrhotics listed for liver transplantat...

journal_title：Gastroenterology research and practice

authors： Ferrarese A,Tikhonoff V,Casiglia E,Angeli P,Fasolato S,Faggian D,Zanetto A,Germani G,Russo FP,Burra P,Senzolo M

更新日期：2018-05-09 00:00:00

abstract：Background:Critically ill patients can benefit from enteral nutrition with postpyloric feeding tubes, but the low success rate limits its wide use. Erythromycin could elevate the success rate of tube insertion, but its clinical efficiency still remains controversial. Methods:Included studies must be RCTs which assesse...

journal_title：Gastroenterology research and practice

authors： Jiang QJ,Jiang CF,Chen QT,Shi J,Shi B

更新日期：2018-04-03 00:00:00

abstract：:Activation of innate immunity is associated with the development of liver disease, including non-alcoholic fatty liver disease (NAFLD). In the innate immune system, Toll-like receptors (TLRs) are sensors that recognize bacterial and viral components such as lipopolysaccharide, bacterial DNA, and peptidoglycan. Recent ...

journal_title：Gastroenterology research and practice

authors： Miura K,Seki E,Ohnishi H,Brenner DA

更新日期：2010-01-01 00:00:00

abstract：Objective:Fucosterol is derived from the brown alga Eisenia bicyclis and has various biological activities, including antioxidant, anticancer, and antidiabetic properties. The aim of this study was to investigate the protective effects of fucosterol pretreatment on Concanavalin A- (ConA-) induced acute liver injury in ...

journal_title：Gastroenterology research and practice

authors： Mo W,Wang C,Li J,Chen K,Xia Y,Li S,Xu L,Lu X,Wang W,Guo C

更新日期：2018-07-17 00:00:00

abstract：:Objective. The aim of the present study was to investigate whether pentraxin 3 (PTX3) can be a new noninvasive marker for prediction of liver fibrosis in patients with NAFLD. We also aimed to evaluate the relationship between PTX3 and atherosclerosis in patients with NAFLD. Method. Fifty-four male patients with biopsy...

journal_title：Gastroenterology research and practice

authors： Ozturk K,Kurt O,Dogan T,Ozen A,Demirci H,Yesildal F,Kantarcioglu M,Turker T,Guler AK,Karslioglu Y,Altun B,Uygun A,Bagci S

更新日期：2016-01-01 00:00:00

abstract：Aim:To determine the risk factors of nonadherence to azathioprine (AZA) maintenance therapy for Crohn's disease (CD) and to evaluate the influence of patients' educational program on adherence to AZA maintenance therapy. Methods:Patients receiving AZA as maintenance therapy for CD were enrolled. Demographic data, clin...

journal_title：Gastroenterology research and practice

authors： Wang L,Fan R,Zhang C,Hong L,Zhang T,Wang Z,Zhong J

更新日期：2020-04-20 00:00:00

abstract：:Background. Functional dyspepsia (FD) is a functional upper gastrointestinal disorder with significant morbidity and medical costs. Previous studies investigated the association of G-protein β3 (GNB3) genetic polymorphisms with FD but with inconsistent results. Therefore, we performed a meta-analysis to derive a preci...

journal_title：Gastroenterology research and practice

authors： Song YZ,You HY,Zhu ZH,Wen ZD,Xu HY,Chen BC,Chen ZJ,Huang QK

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to establish a retrospective evaluation and comparison of the hydrogen/methane (H2/CH4) breath test and genetic test (C/T-13910 polymorphism) results in lactose malabsorption testing. In total 263 consecutive patients with suspected lactose malabsorption were included in this study. They unde...

journal_title：Gastroenterology research and practice

authors： Enko D,Rezanka E,Stolba R,Halwachs-Baumann G

更新日期：2014-01-01 00:00:00

abstract：:Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postcon...

journal_title：Gastroenterology research and practice

authors： Yang M,Dong JX,Li LB,Che HJ,Yong J,Song FB,Wang T,Zhang JW

更新日期：2016-01-01 00:00:00

abstract：Aim:Monocytes play an important role in acute pancreatitis (AP). Hypertriglyceridemic pancreatitis (HTGP) is always more severe than normal lipid-AP, whether the mechanism of aggravation involves monocyte subsets remains unknown though. The present study was aimed to analyze changes of peripheral blood M1 and M2 monocy...

journal_title：Gastroenterology research and practice

authors： Zheng J,Fan J,Huang C,Lu Y,Huang Z,Wang X,Zeng Y

更新日期：2019-06-10 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic cholestatic liver condition characterized by the immune-mediated damage of the intrahepatic bile ducts. Polymorphisms of vitamin D receptor (VDR) are considered to contribute to its pathogenesis however their incidence varies in different populations and their potential ass...

journal_title：Gastroenterology research and practice

authors： Kempińska-Podhorecka A,Wunsch E,Jarowicz T,Raszeja-Wyszomirska J,Loniewska B,Kaczmarczyk M,Milkiewicz M,Milkiewicz P

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study is to investigate the diagnostic efficacy of neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-monocyte ratio (NMR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) in patients with Crohn's disease (CD) and non-CD controls. These ratios were all derived from complete ...

journal_title：Gastroenterology research and practice

authors： Feng JR,Qiu X,Wang F,Chen PF,Gao Q,Peng YN,Lin X,Liu Q,Liu J,Zhao Q,Li J

更新日期：2017-01-01 00:00:00

abstract：Aim:This study aims to analyze factors possibly related to the prognosis of duodenal gastrointestinal stromal tumors (DGISTs). Methods:We collected and retrospectively analyzed clinical and pathological data of 62 patients with primary DGISTs. All the patients were hospitalized and received complete surgical resection...

journal_title：Gastroenterology research and practice

authors： Hong L,Zhang T,Lin Y,Fan R,Zhang M,Cheng M,Zhou X,Sun J,Sun P,Wu Q,Wang L,Wang Z,Zhong J

更新日期：2018-02-20 00:00:00

abstract：Background:Tumor regression grade (TRG) is widely used in gastrointestinal carcinoma to evaluate pathological responses to neoadjuvant chemotherapy (NCT), but whether it is an independent prognostic factor is still controversial. The aim of this study is to investigate the value of TRG in locally advanced gastric adeno...

journal_title：Gastroenterology research and practice

authors： Tong Y,Zhu Y,Zhao Y,Shan Z,Zhang J,Liu D

更新日期：2020-07-18 00:00:00

abstract：Aim:To describe the abnormalities at MR imaging and related complaints in patients with poor outcome after STARR procedure. Materials and Methods:The medical records of 21 symptomatic patients from centre 1, 31 patients from centre 2, and 63 patients from centre 3 were reviewed with regard to findings at MR defecograp...

journal_title：Gastroenterology research and practice

authors： Piloni V,Possanzini M,Bergamasco M,Santi G

更新日期：2017-01-01 00:00:00

abstract：Background and Aims:Functional gastrointestinal disorders (FGDs) are multifactorial disorders of the gut-brain interaction. This study investigated the prevalence of Axis I and spectrum disorders in patients with FGD and established the link between FGDs and psychopathological dimensions. Methods:A total of 135 consec...

journal_title：Gastroenterology research and practice

authors： Stasi C,Nisita C,Cortopassi S,Corretti G,Gambaccini D,De Bortoli N,Fani B,Simonetti N,Ricchiuti A,Dell'Osso L,Marchi S,Bellini M

更新日期：2017-01-01 00:00:00