Abstract:
:Gangliocytic paraganglioma (GP) has been regarded as a rare benign tumor that commonly arises from the second part of the duodenum. As GP does not exhibit either prominent mitotic activity or Ki-67 immunoreactivity, it is often misdiagnosed as neuroendocrine tumor (NET) G1. However, the prognosis might be better in patients with GP than in those with NET G1. Therefore, it is important to differentiate GP from NET G1. Moreover, our previous study indicated that GP accounts for a substantial, constant percentage of duodenal NETs. In the present article, we describe up-to-date data on the clinicopathological characteristics of GP and on the immunohistochemical findings that can help differentiate GP from NET G1, as largely revealed in our new and larger literature survey and recent multi-institutional retrospective study. Furthermore, we would like to refer to differential diagnosis and clinical management of this tumor and provide intriguing information about the risk factors for lymph node metastasis on GP.
journal_name
Gastroenterol Res Practjournal_title
Gastroenterology research and practiceauthors
Okubo Y,Yokose T,Motohashi O,Miyagi Y,Yoshioka E,Suzuki M,Washimi K,Kawachi K,Nito M,Nemoto T,Shibuya K,Kameda Ydoi
10.1155/2016/5257312subject
Has Abstractpub_date
2016-01-01 00:00:00pages
5257312eissn
1687-6121issn
1687-630Xjournal_volume
2016pub_type
杂志文章,评审abstract::Objective. To describe the stroke characteristics of patients with a history of inflammatory bowel disease (IBD). Background. A hypercoagulable state associated with IBD has been frequently implicated as a risk factor for ischemic stroke. Variable mechanisms and infrequent occurrence limit prospective clinical researc...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/672460
更新日期:2015-01-01 00:00:00
abstract:Background:Both long-term proton pump inhibitor use and surgical fundoplication have potential drawbacks as treatments for chronic gastroesophageal reflux disease (GERD). Our aim was to investigate the potential efficacy of antireflux mucosectomy (ARMS) in porcine and determine the optimal circumference of resection in...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2019/3286738
更新日期:2019-02-24 00:00:00
abstract::Despite extensive research, alcohol remains one of the most common causes of liver disease in the United States. Alcoholic liver disease (ALD) encompasses a broad spectrum of disorders, including steatosis, steatohepatitis, and cirrhosis. Although many agents and approaches have been tested in patients with ALD and in...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2016/5491465
更新日期:2016-01-01 00:00:00
abstract::Due to the call for fast KRAS mutation status analysis for treatment of patients with monoclonal antibodies for metastatic colorectal cancer, sensitive, economic, and easily feasible methods are required. Under this aspect, the sensitivity and specificity of the SNaPshot analysis in comparison to the commonly used DNA...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2010/789363
更新日期:2010-01-01 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high rate of mortality and poor prognosis. Numerous studies have proved that microRNA (miRNA) may play a vital role in a wide range of malignancies, including PDAC, and dysregulated miRNAs, including circulating miRNAs, are associated with PDAC...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2014/386561
更新日期:2014-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2014/904307.]. ...
journal_title:Gastroenterology research and practice
pub_type: 已发布勘误
doi:10.1155/2015/804318
更新日期:2015-01-01 00:00:00
abstract::Achieving optimal weight outcomes for patients with obesity is important to the management of their chronic disease. All interventions present risks for weight regain. Bariatric surgery is the most efficacious treatment, producing greater weight losses that are sustained over more time compared to lifestyle interventi...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2013/256145
更新日期:2013-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/819842
更新日期:2012-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/1526981
更新日期:2017-01-01 00:00:00
abstract::Aims. We here investigated whether the combination of simvastatin and irinotecan could induce the synergistic effect on colon cancer cells with or without resistance to irinotecan. Methods. We investigated cell proliferation assay and assessed cell death detection ELISA and caspase-3 activity assay of various concentr...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/7891374
更新日期:2016-01-01 00:00:00
abstract::Reorganization of the actin cytoskeleton underlies cell migration in a wide variety of physiological and pathological processes, such as embryonic development, wound healing, and tumor cell invasion. It has been shown that actin assembly and disassembly are precisely regulated by intracellular signaling cascades that ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2015/930157
更新日期:2015-01-01 00:00:00
abstract:Purpose:Patients with inflammatory bowel disease (IBD) frequently suffer from venous thromboembolic events, and the risk of thromboembolism increases along with disease activity. This study was conducted to discover novel thrombophilic markers using thromboelastography (TEG) and to evaluate the relation between the pre...
journal_title:Gastroenterology research and practice
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doi:10.1155/2020/3245657
更新日期:2020-05-20 00:00:00
abstract:Background and Aims:Endoscopic papillary large balloon dilation (EPLBD) alone is an alternative to endoscopic sphincterotomy (EST) for treatment of common bile duct (CBD) stones. However, limited data exists regarding comparison of the long-term outcomes for these techniques. In this study, we compared the long-term ou...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/6430701
更新日期:2018-07-02 00:00:00
abstract::We determined comparative efficacy of i-Scan for detection and diagnosis of gastric cancer. Ten patients diagnosed with early gastric cancer based on histopathological findings were analyzed. White light and i-Scan moving images recorded from these patients in twin mode were separated into white light and i-Scan. Twel...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/819395
更新日期:2014-01-01 00:00:00
abstract:Background and Aims:Thiopurines are commonly used for treating ulcerative colitis (UC), despite the fact that controlled evidence supporting their efficacy is limited. The aim of this study was to evaluate the long-term outcome of thiopurines as maintenance therapy in a large cohort of UC patients. Methods:All UC pati...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/4195968
更新日期:2018-10-03 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/9415497
更新日期:2016-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/8180323
更新日期:2020-11-28 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/253860
更新日期:2014-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/1615092
更新日期:2018-02-18 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/581523
更新日期:2014-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/2952635
更新日期:2016-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/7532172
更新日期:2016-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/1343969
更新日期:2020-04-21 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2011/631461
更新日期:2011-01-01 00:00:00
abstract::Introduction. Available evidence for routine terminal ileoscopy during colonoscopy is equivocal. We investigated the place of routine terminal ileoscopy and biopsy during colonoscopy, in a tropical setting. Materials and Methods. All consenting adults undergoing colonoscopy had routine TI and biopsy. Patients with rig...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/343849
更新日期:2014-01-01 00:00:00
abstract::Purpose. In the present study, the prognostic significance of CpG island methylator phenotype (CIMP) in stage II/III sporadic colorectal cancer was evaluated using a five-gene panel. Methods. Fifty stage II/III colorectal cancer patients who received radical resection were included in this study. Promoter methylation ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
abstract::Clostridium difficile toxin A is a colonic inflammatory agent that acts partially by activation of TRPV1 (transient receptor potential vanilloid type 1). Resiniferatoxin (RTX) is an excitotoxin that activates TRPV1 at low concentrations and defunctionalizes TRPV1 at high concentrations. RTX at various doses was inject...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/8438172
更新日期:2017-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/3435673
更新日期:2020-07-18 00:00:00
abstract::The injurious effects of NSAIDs on the small intestine were not fully appreciated until the widespread use of capsule endoscopy. It is estimated that over two-thirds of regular NSAID users develop injury in the small intestinal injuries and that these injuries are more common than gastroduodenal mucosal injuries. Rece...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2013/761060
更新日期:2013-01-01 00:00:00
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journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/504179
更新日期:2015-01-01 00:00:00