Abstract：
:Padina sanctae-crucis Børgesen is distributed worldwide in tropical and subtropical seas; belongs to the Dictyotaceae family, and has proven to be an exceptional source of biologically active compounds. Four compounds were isolated and identified, namely: dolastane diterpene new for the genus Padina; phaeophytin and hidroxy-phaeophytin new for the family Dictyotaceae, and; mannitol first described in this species. Saturated fatty acids as compared to the percentages of unsaturated fatty acids were shown to be present in greater abundance. Palmitic and linolenic acid were the main saturated and unsaturated acids, respectively. Cytotoxic and antioxidant activities were evaluated using human erythrocytes. In vivo evaluations of acute toxicity and genotoxicity were performed in mice. Methanolic extract of P.sanctae-crucis presented antioxidant activity and did not induce cytotoxicity, genotoxicity or acute toxicity. Since Padina sanctae-crucis is already used as food, has essential fatty acids for the nutrition of mammals, does not present toxicity and has antioxidant activity, it can be considered as a potential nutraceutical.
journal_name
Mar Drugsjournal_title
Marine drugsauthors
Nogueira RBSS,Tomaz ACA,Pessoa DR,Xavier AL,Pita JCLR,Sobral MV,Pontes MLC,Pessôa HLF,Diniz MFFM,Miranda GEC,Vieira MAR,Marques MOM,Souza MFV,Cunha EVLdoi
10.3390/md15100251subject
Has Abstractpub_date
2017-09-26 00:00:00issue
10issn
1660-3397pii
md15100251journal_volume
15pub_type
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