Abstract:
:Cell size control and homeostasis is a long-standing subject in biology. Recent experimental work provides extensive evidence for a simple, quantitative size homeostasis principle coined adder (as opposed to sizer or timer). The adder principle provides unexpected insights into how bacteria maintain their size without employing a feedback mechanism. We review the genesis of adder and recent cell size homeostasis study on evolutionarily divergent bacterial organisms and beyond. We propose new coarse-grained approaches to understand the underlying mechanisms of cell size control at the whole cell level.
journal_name
Curr Opin Cell Bioljournal_title
Current opinion in cell biologyauthors
Sauls JT,Li D,Jun Sdoi
10.1016/j.ceb.2016.02.004subject
Has Abstractpub_date
2016-02-01 00:00:00pages
38-44eissn
0955-0674issn
1879-0410pii
S0955-0674(16)30011-4journal_volume
38pub_type
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journal_title:Current opinion in cell biology
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