Structure and function of telomerase.

Abstract:

:The study of eukaryotic telomeres at the molecular level began with the discovery of short, tandem repeats at Tetrahymena chromosome ends. In the following two decades, major insights about telomere structure and function have come from investigations of telomerase, the DNA polymerase that synthesizes these repeats. In the past year, three areas of telomerase research have been particularly intense: assays of telomerase activity, isolation of telomerase components, and studies of the regulation of telomerase and telomere length in vivo.

journal_name

Curr Opin Cell Biol

authors

Collins K

doi

10.1016/s0955-0674(96)80013-5

subject

Has Abstract

pub_date

1996-06-01 00:00:00

pages

374-80

issue

3

eissn

0955-0674

issn

1879-0410

pii

S0955-0674(96)80013-5

journal_volume

8

pub_type

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