Abstract:
BACKGROUND:Aspartate aminotransferase (AST) is an enzyme normally confined to the cytoplasm of cells, but released to the exracellular environment upon cell death. Its levels are associated with the severity of experimental gingivitis and the loss of periodontal attachement. The aim of the present study was to investigate the presence and activity levels of AST in peri-implant crevic-ular fluid (PCF) healthy and diseased endosseous implants in order to assess if AST in PCF can be further studied as a possible objective diognostic aid in oral implantology. METHODS:Eighty-one fitures from 81 systemically healthy subject were divide into 3 groups, 27 healthy implants (HI), 27 implants with mucositis (MI) and 27 implants affected by periimplantities (PI)according to well-defined clinical and radiographic criteria. PCF was collected by the insertion of a # 40 standardized - point to the base of the crevice or pocket for 30 seconds. AST activity was determined spectrophotometrically at 25' C. The results were expressed as AST Units/ml in PCF. RESULTS:An AST activity was detected in each sample from HI, MI and PI. The mean AST activity in HI was 0.26 f 0.16 U/ml; in MI, 0.38 ± 0.27u/ml; in PI, 0.62 k 0.29 U/ml. ANOVA showed that the deference among HI, MI, and PI was statistically significant at P <0.01level. Post-hoc tests demonstrated that a significant difference in AST activity existed between HI/PI (t = 5.14; P <0.01) and MI/PI (t = 3.09; P <0.01). No statistically significant difference was fond between HI/MI (t = 1.07; P>0.1) AST activity was significantly (P <1) associated with probing depth (r = 0.55), the amount of bone loss (r = 0.60) and bleeding on probing (r = 0.67). When the threshold for a positive AST test was set ≥0.4 U/ml, a sensitivity = 0.81 and a specificity = 0.74 were found in the detection of peri-implantitis; the positive predictive value was 61% and the negative predictive value was 88%. CONCLUSIONS:within the limits of this study, our results may suggest the PCF analysis could be further investigated in longitudi-nal studies as a suitable diagnostic strategy in the evaluation of dental implants. J Periodontol2000;71:1151-1157.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Paolantonio M,Di Placido G,Tumini V,Di Stilio M,Contento A,Spoto Gdoi
10.1902/jop.2000.71.7.1151subject
Has Abstractpub_date
2000-07-01 00:00:00pages
1151-1157issue
7eissn
0022-3492issn
1943-3670journal_volume
71pub_type
杂志文章abstract::A 26-year-old hispanic male presented with a nonspecific gingival lesion initially presumed to be of infectious etiology. During continued follow-up over several weeks, the lesion evolved into one typical of desquamative gingivitis. Direct immunofluorescent testing and routine histopathology resulted in a diagnosis of...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.9.611
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus (DM) is a major risk factor for periodontal disease and affects various cellular functions. Periodontal ligament stem cells (PDLSCs) play an important role in periodontal tissue regeneration; however, the effect of hyperglycemia on PDLSCs is unclear. The aim of this study is to investigate ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2015.150474
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Platelet-derived growth factor (PDGF-BB) has been shown to enhance periodontal regeneration. Principles of guided tissue regeneration dictate that one of the goals of therapy is to modulate the wound healing processes to favor repopulation of the wound with cells derived from the periodontal ligament rather ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.3.331
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Neutrophils (PMNs) are critical components of the innate immune system and help to maintain oral health in the face of a constant bacterial challenge. However, along with protecting the periodontium from microbial invasion, these cells release potent lysosomal enzymes and oxygen radicals that can be destruct...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.070107
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:A 10-year follow-up study was conducted to clinically evaluate the long-term results after guided tissue regeneration (GTR) therapy of infrabony defects using non-resorbable and bioabsorbable barriers. METHODS:Twelve pairs of contralateral infrabony defects were treated in 12 subjects with advanced periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2008.070571
更新日期:2008-08-01 00:00:00
abstract::Linear IgA disease (LAD) is a chronic, subepithelial blistering disease that is associated with the presence of linear deposits of IgA along the basement membrane zone. Etiopathogenic aspects of LAD are only partially known. LAD is clinically characterized by vesiculobullous skin and mucous lesions. Although more than...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.6.879
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans), a capnophilic facultative anaerobe, is associated with localized aggressive periodontitis and endocarditis. When grown in broth, the cells begin to die rapidly after overnight growth. The cells also often lose viability ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100590
更新日期:2011-06-01 00:00:00
abstract::The clinical, histopathologic and functional consequences of the genetic deficiency of leukocyte Mac-1, LFA-1 and p150,95 were assessed among three affected patients, heterozygotes and unaffected individuals among two generations of a single kindred. Longitudinal assessments of this family afforded the unique opportun...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.6.400
更新日期:1987-06-01 00:00:00
abstract::In order to compare the effect of partial demineralization with root planing and partial demineralization of cementum with that of dentin on healing, the ultrastructural morphology of the interface between the layer of human periodontal ligament-derived, fibroblast-like cells (HPF) and the treated root surface was stu...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.4.267
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. To the best knowledge of the authors, there are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known micr...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160273
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:One of the success factors in periodontal plastic surgery is the synergistic relationship between involved tissues and vascular supply. Gingiva as a functional unit is unique with a specific vascular configuration and contains the supracrestal portion naturally created to survive over avascular root surfaces...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2012.110685
更新日期:2013-01-01 00:00:00
abstract::The purpose of this single blind clinical study was to determine the effects of two commerical mouthwashes (one containing cetylpyridinium chloride and domiphen bromide and the other containing only cetlypridinium chloride) on existing plaque accumulations. A second purpose was to determine if a residual effect could ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1976.47.7.419
更新日期:1976-07-01 00:00:00
abstract::Healing of extraction sockets where the buccal plate of bone has been destroyed often results in localized ridge deformities. This is most likely due to the ingrowth of extraskeletal connective tissue into the space originally occupied by the tooth which then fills with a combination of bone and soft tissue. Technique...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1994.65.1.17
更新日期:1994-01-01 00:00:00
abstract::To quantify patient perceptions of periodontal therapy, we administered a self-report questionnaire employing a visual analog scale (VAS) to 162 patients following surgical and non-surgical treatments. The questionnaire tested for variables of pain, sensitivity, swelling, function, altered appearance, comparison of po...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.10.990
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to perform alveolar ridge augmentation by distraction osteogenesis (DO) and to enhance bone regeneration through the use of recombinant human bone morphogenetic protein-2 (rhBMP-2), followed by implant placement. METHODS:Alveolar segmental osteotomy was performed in the mandibl...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.11.1524
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Gingival thickness, keratinized tissue width, and bone morphotype are three important parameters used to categorize periodontal phenotypes. These elements all play an important role in the maintenance of periodontal health. The aim of this review is to explore the importance of converting thin phenotype into...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1002/JPER.19-0337
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:In sinus augmentation, when remaining bone height is ≤5 mm, a lateral window approach is often the preferred choice; nonetheless, patients prefer to have a less invasive approach such as crestal sinus augmentation (CSA). Prior case reports have described the use of various staged approaches of a CSA techniqu...
journal_title:Journal of periodontology
pub_type:
doi:10.1002/JPER.18-0632
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Cyclosporin A (CsA) induces gingival overgrowth (GO) in patients who seem to be prone to this disorder. It is still impossible to determine which patients will develop GO. Patients treated with the new immunosuppressive drug tacrolimus seem not to have GO. The aims of this study were to investigate transform...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050086
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Metastases to the oral mucosa are rare, representing less than 1% of the tumors at this site. Most of these metastatic neoplasms originate in the lungs, kidneys, and liver. METHODS:The clinicopathologic features of an occult hepatocellular carcinoma, metastatic to the oral mucosa, are reported. The patient,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.4.641
更新日期:2000-04-01 00:00:00
abstract::The cross-sectional relationship between severe loss of periodontal attachment (LPA) and worsening immune status due to HIV infection was evaluated in 474 HIV-infected subjects (416 men, 58 women) aged 18 to 49 years who had been classified at stages 1 through 6 of the Walter Reed Army Institute of Research (WR) Stagi...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.6.421
更新日期:1995-06-01 00:00:00
abstract::The inter-incisal distance and dimension of the interdental papilla between the mandibular incisors were examined in cyclosporin A (CSA) fed rats over 6 weeks. Rats in the test group received CSA daily in mineral oil by gastric feeding (30 mg/kg body weight); the control group received mineral oil only. The inter-inci...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1997.68.12.1231
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:Gingival melanin depigmentation procedures are commonly associated with recurrence of pigmentation, which starts with migration of melanocytes from the adjacent free gingiva. The extent and rate of recurrence varies according to the treatment modalities used and duration of follow-up. The aim of this study i...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.120094
更新日期:2013-06-01 00:00:00
abstract::The purpose of this study was to evaluate interexaminer and intraexaminer probing force variations in various regions of the mouth and adjacent to different tooth surfaces. Fifty-eight dental clinicians composed of 13 periodontists, 15 general dentists, 15 hygienists and 15 senior dental students probed the facial sur...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1983.54.8.488
更新日期:1983-08-01 00:00:00
abstract::The relation between utilization of dental services from community dentists and the extent and severity of alveolar bone loss is reported for a panel of men followed for over 6 years. Oral health data were collected by the Department of Veterans Affairs, Dental Longitudinal Study, which began in 1969 and still continu...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1994.65.5s.551
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Metastasis of a malignant tumor to the oral cavity is rare, but it can be the first manifestation of a primary tumor. METHODS:The clinicopathologic features of a gingival metastasis originating from lung adenocarcinoma in a female patient are described. A 57-year-old woman showed a rapidly growing, painless...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070246
更新日期:2008-01-01 00:00:00
abstract::Clinical and laboratory data were compared in 72 patients with localized periodontitis (LP) and 103 patients with generalized periodontitis (GP). Significantly more LP than GP cases had decreased neutrophil chemotaxis (CTX), and were seropositive for Actinobacillus actinomycetemcomitans (Aa). Significantly, more GP ca...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1989.60.10.557
更新日期:1989-10-01 00:00:00
abstract::Supragingival plaque and calculus indices, salivary flow rates, pH, ionic and total calcium concentrations, total phosphate concentration, and the number of cervical restorations and caries lesions were measured in 29 subjects using systemic beta-(beta) blockers and in 28 subjects who were not taking any systemic medi...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1996.67.4.428
更新日期:1996-04-01 00:00:00
abstract::The purpose of this study was to assess the clinical and microbiological effects of a newly developed root conditioning gel system containing tetracycline or a mixture of tetracycline and citric acid on non-surgical periodontal therapy. Sixty-four (64) single-rooted teeth with a probing depth of 4 to 6 mm were randoml...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1994.65.9.840
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Procedures to improve peri-implant soft-tissue outcomes of single, immediately placed implants are a topic of interest. This systematic review investigates the effect of various surgical and restorative interventions on implant mid-buccal mucosal level. METHODS:An electronic search of five databases (Januar...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2013.130064
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:This case report describes a 22-year-old female who was referred with a radiolucent lesion between her mandibular right molars. The original radiographic image suggested an odontogenic cyst. METHODS:The surgical enucleation and osteotomy of the residual cavity were performed with a piezoelectric knife. Hist...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060417
更新日期:2007-07-01 00:00:00