Abstract:
BACKGROUND:Gingival melanin depigmentation procedures are commonly associated with recurrence of pigmentation, which starts with migration of melanocytes from the adjacent free gingiva. The extent and rate of recurrence varies according to the treatment modalities used and duration of follow-up. The aim of this study is to compare the surgical stripping; carbon dioxide (CO2); and erbium-doped:yttrium, aluminum, and garnet (Er:YAG) laser techniques for gingival depigmentation and to evaluate their effect on histologic changes in melanocyte activity and clinical repigmentation. METHODS:In this study, 140 sites from 35 patients with bilateral melanin hyperpigmentation were treated with surgical stripping (two sites per patient), "epithelial-peel" (CO2 laser, 2 to 4 W, continuous wave),and "brushstroke" (Er:YAG laser, 180 mJ, 10 Hz, long pulse) techniques. Surgical microscope monitoring was performed intraoperatively. Patient preference and perception of pain, change in Dummett oral pigmentation index (DOPI), Hedin index, and change in area of pigmentation from baseline to 6 months postoperatively were recorded. Twenty samples each from the three treatment modalities were selected for histologic analysis using hematoxylin and eosin and dihydroxyphenylalanine oxidase special stains. RESULTS:At the 6-month postoperative visit, 15 of 70 (21.4%) and three of 20 (15%) of the surgical-treated; 10 of 35 (28.6%) and six of 20 (30%) of the Er:YAG-laser-treated; and eight of 35 (22.8%) and four of 20 (20%) of the CO2-laser-treated sites showed clinical and histologic repigmentation, respectively. Paired t test, analysis of variance, and χ(2) tests were used for statistical analyses. P values for comparison of microscopic evaluation, change in DOPI, Hedin index, and area of pigmentation were 0.001, which were statistically significant. Comparison for patient preference and pain indices gave statistically significant values for Er:YAG laser depigmentation (P = 0.001). CONCLUSIONS:Clinical repigmentation after gingival depigmentation is an outcome of histologic changes in the melanocyte activity and density of the melanin pigments. Surgical stripping for gingival depigmentation remains the gold standard; however, Er:YAG laser and CO2 lasers can be effectively used but with distinct differences.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Hegde R,Padhye A,Sumanth S,Jain AS,Thukral Ndoi
10.1902/jop.2012.120094subject
Has Abstractpub_date
2013-06-01 00:00:00pages
738-48issue
6eissn
0022-3492issn
1943-3670journal_volume
84pub_type
杂志文章abstract::Oral melanin pigmentation is not uncommon in some races and ethnic groups. Repigmentation of depigmented oral mucosa has been described after chemical, thermal, surgical, pharmacologic or idiopathic factors. Information on the repigmentation of oral tissues after surgical procedures is extremely limited. The communica...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1986.57.1.48
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:A major challenge for dental implantology is to consistently obtain appropriate bone augmentation before implant placement. The aim of this study is to evaluate the effect of recombinant human bone morphogenetic protein 2 (rhBMP-2) associated with bone substitute materials beta-tricalcium phosphate (β-TCP), ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110674
更新日期:2013-03-01 00:00:00
abstract::Nineteen young adult Caucasian males had an average Gingival Index Score of 0.47. Each was asked to demonstrate his present method of toothbrushing: thirteen used the scrub method, and six combined the scrub and roll methods. Control gingival tissue specimens were taken from the mandibular left first bicuspid or first...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.4.163
更新日期:1978-04-01 00:00:00
abstract::The Keyes technique came to national attention following a reference in The New York Times in the late 1970s. Several lay press articles and discussions on national television served to further focus the interest of patients, general dentists, and periodontists on this potential approach to periodontal therapy. Early ...
journal_title:Journal of periodontology
pub_type: 杂志文章,收录出版
doi:
更新日期:1998-08-01 00:00:00
abstract::A multitude of new procedures and materials are being tested for their ability to promote periodontal wound healing. This review provides an overview of the most well-accepted methods for evaluating periodontal wound healing procedures/materials. Topics discussed include appropriate patient selection, general principl...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.12s.1085
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Periodontal root coverage procedures to treat recession areas are indicated for unesthetic, exposed, and/or painful root surfaces. Many methods, most using autogenous soft tissue grafts, have been utilized, but with associated morbidity at the donor sites. An alternative donor material would reduce the morbi...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2001.72.8.998
更新日期:2001-08-01 00:00:00
abstract::In this investigation periodontal destruction was produced by a combination of inflammatory and traumatic factors. After the inflammation was resolved and the trama stopped, a significant amount of alveolar bone regeneration took place. The implications of these findings for the management of advanced periodontal dise...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1976.47.12.687
更新日期:1976-12-01 00:00:00
abstract::Periodontal diseases are thought to result from inflammatory responses to bacterial challenges in the gingival crevicular area. Antibodies are a major host-protective mechanism in many bacterial infections. Consequently, the antibody responses to suspected periodontal pathogenic bacteria have been extensively measured...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1993.64.8s.807
更新日期:1993-08-01 00:00:00
abstract::Periodontal data typically have a hierarchical structure, with sites grouped within individuals, and individuals grouped within communities. Also, the occasion may be regarded as another level since the acquired knowledge indicates that periodontal disease activity may vary over time. Conventional statistical tests ar...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.8.690
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:Prostaglandin E2 (PGE2 ), which exerts its actions via EP receptors (EP1 , EP2 , EP3 , and EP4 ), is a bioactive metabolite produced by cyclooxygenase (COX)-1 and/or COX-2 from arachidonic acid. In the present study, we investigated whether COX-2-derived PGE2 regulated matrix metalloproteinase (MMP)-3 produc...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.6.929
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Little evidence is available regarding the effects of long-term periodontal infection on diabetes mellitus (DM) control. The aim of this retrospective cohort study is to evaluate influence of periodontal status on changes of glycated hemoglobin (HbA1c) levels of patients with type 2 DM (DMt2). METHODS:Eight...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160140
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Metastases to the oral mucosa are rare, representing less than 1% of the tumors at this site. Most of these metastatic neoplasms originate in the lungs, kidneys, and liver. METHODS:The clinicopathologic features of an occult hepatocellular carcinoma, metastatic to the oral mucosa, are reported. The patient,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.4.641
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Enhanced neutrophil responses play a critical role in the activation of the innate immune system and causation of aggressive periodontitis (AgP). The hypothesis that comprehensive periodontal treatment expedites resolution of amplified leukocyte activity and facilitates the reconstitution of periodontal heal...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2002.73.9.995
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:The aim of this study was to compare the clinical outcome of intrabony periodontal defects following treatment with a novel nanocrystalline hydroxyapatite (NHA) paste to open flap debridement. METHODS:Twenty-eight subjects, each displaying one intrabony defect with probing depth (PD) > or =6 mm and radiogra...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2008.070378
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:This study examined conditions under which gingival crevicular blood (GCB) could be used to obtain a useful glucose reading to screen for undiagnosed diabetes during routine dental visits. METHODS:GCB and capillary finger-stick blood (CFB) glucose readings obtained with a glucometer were compared for 46 pat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2009.080542
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:In the treatment of periodontal intrabony defects, the benefits of adding platelet-rich plasma (PRP) to a bone replacement grafting material have not been tested. The purpose of this study was to compare the clinical outcomes obtained by the combination of PRP and a bovine derived xenograft (BDX) to those ob...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2004.75.12.1668
更新日期:2004-12-01 00:00:00
abstract::Supragingival plaque and calculus indices, salivary flow rates, pH, ionic and total calcium concentrations, total phosphate concentration, and the number of cervical restorations and caries lesions were measured in 29 subjects using systemic beta-(beta) blockers and in 28 subjects who were not taking any systemic medi...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1996.67.4.428
更新日期:1996-04-01 00:00:00
abstract:SCOPE:These Guidelines apply to products used to promote the regeneration of periodontal tissues lost due to periodontal diseases or other causes. Periodontal regeneration is defined histologically as regeneration of the tooth's supporting tissues, including alveolar bone, periodontal ligament, and cementum over a prev...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1998.69.9.1081
更新日期:1998-09-01 00:00:00
abstract::Langerhans cells (LC) are antigen-presenting cells which express high levels of Class II MHC antigens on their plasma membranes. While the expression of these antigens on gingival LC has been documented, their functional significance is unclear. In this study, the mixed epithelial cell-lymphocyte culture reaction (MEC...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.6.328
更新日期:1990-06-01 00:00:00
abstract::This study investigated a possible association between bruxism and severity of periodontal disease. Subjects consisted of 51 patients (mean age 47.3 years) referred to the Department of Periodontology for treatment of moderate to severe periodontal disease (Perio-group) and 40 patients (mean age 48.9 years) referred t...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.3.173
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:Subantimicrobial-dose doxycycline (SDD) is widely used as an adjunctive treatment to scaling and root planing (SRP), but its long-term effectiveness remains controversial. The purpose of this systematic review was to assess the actual evidence of the effectiveness of SRP + SDD compared to SRP + placebo in th...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1902/jop.2011.110026
更新日期:2011-11-01 00:00:00
abstract::The botryoid odontogenic cyst is considered to be a multiloculated variant of the lateral periodontal cyst. Fewer than 40 of these lesions have been described, many of which have recurred. This paper describes the demographic, clinical, microscopic, and radiographic features of 33 unreported cases from the files of th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.12.1069
更新日期:1995-12-01 00:00:00
abstract::T-cell subsets extracted from chronically inflamed periodontal tissues were identified using monoclonal antibodies, and their functional activity was analysed using the autologous mixed lymphocyte reaction (AMLR). Tissue was obtained from a total of 33 adult periodontitis (AP) patients and 6 normal/marginal gingivitis...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.8.569
更新日期:1987-08-01 00:00:00
abstract:BACKGROUND:Morning breath odor is an often-encountered complaint. This double-blind, crossover, randomized study aimed to examine the bad breath-inhibiting effect of 3 commercially available mouthrinses on morning halitosis during an experimental period of 12 days without mechanical plaque control. METHODS:Twelve medi...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2000.72.9.1183
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Periodontitis patients harboring Actinobacillus actinmycetemcomitans (Aa) are prime candidates for systemic antibiotic therapy. Besides tetracycline and the combination of metronidazole and amoxicillin the fluoroquinolones are also believed to have antibacterial activity against Aa. The aim of the present st...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2000.71.2.202
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:It is unknown whether cone beam computed tomography (CBCT) image reconstruction characteristics, including section thickness, may affect linear bone measurements of periodontal intrabony defects. The aim of this study was to compare intrasurgical and CBCT-based linear measurements of intrabony defects focusi...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.20-0338
更新日期:2020-08-21 00:00:00
abstract:BACKGROUND:Implants replacing missing teeth provide advantages over clinical orthodontic treatment as compensation for reaction forces is no longer necessary and the lack of teeth is immediately resolved. METHODS:A total of 38 two-stage implants were inserted (16 in maxilla, 22 in mandible) in 10 partially edentulous ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.1.176
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study is to evaluate whether β-tricalcium phosphate (β-TCP) could be a promising modality to help augment alveolar bone in periodontal tissue regeneration by bone marrow mesenchymal stem cells (BMMSCs). METHODS:Expanded BMMSCs and atelocollagen (Col) were mixed together (MSC/Col). A comb...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.140384
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Gingival augmentation procedures are indicated primarily to increase an insufficient amount of gingiva and sometimes to halt the progression of gingival recession. The aim of this retrospective long-term study was to evaluate changes in the amount of keratinized tissue (KT) and in the position of the gingiva...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070414
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Periodontal wound healing has been accelerated by different low-level laser therapy (LLLT) protocols. However, just a few studies have evaluated use of this therapy adjunctive to periodontal plastic surgery procedures. The present study shows 2-year results of a connective tissue graft (CTG) associated with ...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2016.160391
更新日期:2017-04-01 00:00:00