Abstract:
:Periodontal data typically have a hierarchical structure, with sites grouped within individuals, and individuals grouped within communities. Also, the occasion may be regarded as another level since the acquired knowledge indicates that periodontal disease activity may vary over time. Conventional statistical tests are based on unilevel analysis of data. However, this approach to statistical analysis is often inconvenient in periodontal research because of the variation in the outcome variables between the various levels in the hierarchy. Lately there have been important developments in the statistical theory which have made available powerful statistical techniques for analyzing multilevel or hierarchical data. This report describes a new approach for analyzing periodontal data and uses an illustrative example to build a model which explains part of the variability in the response variable. The results from this analysis are then compared to results from an earlier report which uses unilevel methods and the findings discussed. The present multilevel approach has several advantages over unilevel methods, mainly due to its statistical validity and efficiency. Further, it permits the incorporation of explanatory variables measured at the site and the subject levels, and those which vary across the time points. Multilevel analyses have a promising potential and are expected to have a significant impact on periodontal research.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Albandar JM,Goldstein Hdoi
10.1902/jop.1992.63.8.690subject
Has Abstractpub_date
1992-08-01 00:00:00pages
690-5issue
8eissn
0022-3492issn
1943-3670journal_volume
63pub_type
杂志文章abstract:BACKGROUND:Maintaining normal weight, engaging in the recommended level of exercise, and eating healthy food are known to improve general health. The impact of these behaviors on periodontal health is not well documented. This study is aimed at examining whether the increased number of these behaviors is associated wit...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.8.1362
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Recent research indicated that periodontal infection may worsen systemic diseases, including pulmonary disease. Respiratory infections, such as pneumonia and the exacerbation of chronic obstructive pulmonary disease, involve the aspiration of bacteria from the oropharynx into the lower respiratory tract. ME...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.100582
更新日期:2011-08-01 00:00:00
abstract::The purpose of the present study was to use a novel intracrevicular lavage technique to evaluate short-term effects of phase I therapy on crevicular cell populations. Nineteen patients with untreated advanced adult periodontitis were selected for phase I therapy. One side of the dentition was treated with ultrasonic c...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1995.66.3.235
更新日期:1995-03-01 00:00:00
abstract::The aim of the present investigation was to evaluate the effectiveness of collagen membrane placement in excluding gingival epithelium and connective tissue cells and guiding new attachment in surgical treatment of created defects in dogs. Sixty defects were chosen at random and balanced in regard to receiving the fol...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.12.830
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:It has been proposed that the presence of a zone of keratinized mucosa (KM) around implants is associated with less discomfort during brushing and improved esthetic outcomes. Therefore, mucogingival procedures have been recommended for patients with discomfort during brushing, and to enhance esthetic results...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.18-0031
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:A specific labeler of the human gingival fibroblast (HGF) does not exist. Anionic maghemite nanoparticles allow labeling of a wide cell variety and their recognition in cellular, organotypical, and animal models. METHODS:We studied internalization effects of nanoparticles on an HGF phenotype in vitro, evalu...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050064
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Periodontitis and osteoporosis are characterized by the loss of bone mass. Osteocalcin levels have been postulated as a marker of inhibition of bone formation. The aim of the present study was to assess plasma, saliva, and gingival crevicular fluid (GCF) levels of osteocalcin and correlate them with periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.4.513
更新日期:2005-04-01 00:00:00
abstract::Repeated measurements of attachment level appear to be important assessments in periodontal clinical trials, yet the lack of reliability for this assessment creates measurement error which in turn demands increased sample sizes or reduces the power of the test. A plastic occlusal stent has been developed as a fixed re...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.2.115
更新日期:1987-02-01 00:00:00
abstract::A study was undertaken to evaluate the antigenic potential of allogeneic freeze-dried skin (FDS) when used as a grafting material and to examine the clinical results when FDS is used for the correction of mucogingival problems in humans. FDS was obtained from an HLA-tissue-type donor according to Navy Tissue Bank prot...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1980.51.10.571
更新日期:1980-10-01 00:00:00
abstract::A review of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu Disease) is presented. Special emphasis is placed on the oral manifestations which include hemorrhagic vesicles, nodules, papules and ulcers that involve the gingiva and other areas of the mucosa. Two cases are included which were seen in a periodont...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1982.53.3.163
更新日期:1982-03-01 00:00:00
abstract:BACKGROUND:The objective of this study was to histologically evaluate periodontal healing following flap surgery in intrabony periodontal defects to determine the influence of the number of bone walls on periodontal regeneration. METHODS:One-, 2-, and 3-wall intrabony periodontal defects were surgically produced at th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.2.229
更新日期:2004-02-01 00:00:00
abstract::The purpose of this study was to evaluate the effects of the Nd:YAG laser on in vitro fibroblast attachment to endotoxin-treated root surfaces and to describe any laser-induced cementum surface alterations. Thirty 4 mm x 4 mm cementum segments were obtained from unerupted third molars. The treatment groups were as fol...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.7.626
更新日期:1992-07-01 00:00:00
abstract::In previous studies Fusobacterium nucleatum has been shown to induce either stimulatory or inhibitory effects on human mononuclear cells. We examined the interaction of human mononuclear cells with human and cynomolgus monkey strains of F. nucleatum. Peripheral blood mononuclear cells (PBMCs) isolated from normal dono...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1997.68.1.39
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:The purpose of the present study was to assess the effects of adjunctive meloxicam on the matrix metalloproteinase-8 (MMP-8) levels of gingival crevicular fluid (GCF) in chronic periodontitis patients following the initial phase of periodontal therapy. METHODS:Twelve chronic periodontitis patients received ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2002.73.1.103
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. To the best knowledge of the authors, there are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known micr...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160273
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:An experimental periodontal sensor probe (SP) equipped with an optical fiber for recording function was developed. The aim was to test the intraexaminer reproducibility of probing using the SP and to assess the consistency with the manual probe (MP). METHODS:The SP was assembled with an external sheath cove...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2011.110047
更新日期:2012-02-01 00:00:00
abstract::A total of 305 dry human skull specimens were examined for the presence of furcation involvements. Of a total of 188 furcation involvements, 142 (75%) were related to the close proximity of the furcation to the cemento enamel junction of the tooth. ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1975.46.10.608
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:Most dental implants are positioned using a drilling surgery technique. However, dentistry recently experienced the implementation of piezoelectric surgery. This technique was introduced to overcome some of the limitations involving rotating instruments in bone surgery. This study used biomolecular and histo...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060285
更新日期:2007-04-01 00:00:00
abstract::Gingival biopsies of the mesial papilla area of the first molar were obtained from each patient at 0-, 14- and 21-day intervals during plaque formation. The biopsies were fixed, serially sectioned, and Gram-stained. The incidence and distribution of the bacteria-like structures were studied by microscopy. In all the s...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.12.837
更新日期:1987-12-01 00:00:00
abstract::Saliva and serum samples were collected from 36 individuals with selective immunoglobulin A deficiency (IgAd) and 23 patients with common variable immunodeficiency (CVI). The oral examination included registration of the teeth, Russell's periodontal index (PI), pocket formation, and salivary flow rate in both unstimul...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.12.984
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Only a few studies have examined the association between periodontitis and glycated hemoglobin (HbA1c) levels in individuals without diabetes. The aim of this study is to compare HbA1c levels in individuals without diabetes and with and without periodontitis before and after non-surgical periodontal therapy....
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.130661
更新日期:2014-12-01 00:00:00
abstract::Matrix metalloproteinases (MMP) are a family of proteolytic enzymes that mediate the degradation of extracellular matrix macromolecules, including interstitial and basement membrane collagens, fibronectin, laminin, and proteoglycan core protein. The enzymes are secreted or released in latent form and become activated ...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1993.64.5s.474
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Morning breath odor is an often-encountered complaint. This double-blind, crossover, randomized study aimed to examine the bad breath-inhibiting effect of 3 commercially available mouthrinses on morning halitosis during an experimental period of 12 days without mechanical plaque control. METHODS:Twelve medi...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2000.72.9.1183
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Lysine, a nutritionally essential amino acid, enters the oral cavity in gingival crevicular fluid (GCF). During oral hygiene restriction (OHR), lysine decarboxylase (LDC) in dento-gingival biofilms converts lysine to cadaverine. Lysine depletion impairs the dental epithelial barrier to bacterial proinflammat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2015.140490
更新日期:2015-10-01 00:00:00
abstract::The purpose of this study was to conduct a direct comparison of two dose regimens of minocycline to determine 1) whether they achieved crevicular fluid concentrations in a therapeutic range; and 2) the frequency of side effects. In a double-blind design, 30 patients divided into 2 groups were given either 100 mg minoc...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1992.63.1.13
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Cyclosporin A (CsA) induces gingival overgrowth (GO) in patients who seem to be prone to this disorder. It is still impossible to determine which patients will develop GO. Patients treated with the new immunosuppressive drug tacrolimus seem not to have GO. The aims of this study were to investigate transform...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050086
更新日期:2006-05-01 00:00:00
abstract::This report describes a case of rapidly progressive periodontal tissue breakdown and bone loss in an HIV-infected markedly immunosuppressed homosexual male. Within 6 months of initial presentation with a necrotizing ulcerative gingivitis, the lesion extended to a necrotizing ulcerative stomatitis involving the surroun...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1998.69.6.710
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Reconstruction and rehabilitation of atrophic maxillae with bone grafts is a lengthy and demanding procedure. This study reports the immediate loading of 50 implants placed on six extremely atrophied edentulous maxillae reconstructed with Le Fort I osteotomy and iliac bone grafting. METHODS:Six patients, ag...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110460
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:A relationship between periodontitis and chronic respiratory disease has been suggested by recent studies. The aim of this study is to explore the association between periodontitis and chronic obstructive pulmonary disease (COPD) in a Chinese population. METHODS:We conducted a case-control study of 581 COPD...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110472
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Simvastatin has been shown to stimulate new bone growth on rat mandibles, but much of the bone is lost over time. The purpose of this study is to evaluate the impact of a locally or systemically applied antiresorptive agent (alendronate) on simvastatin-induced bone formation in and adjacent to a rat periodon...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110683
更新日期:2012-12-01 00:00:00