Rapid progression of bone loss in HIV-associated necrotizing ulcerative stomatitis.


:This report describes a case of rapidly progressive periodontal tissue breakdown and bone loss in an HIV-infected markedly immunosuppressed homosexual male. Within 6 months of initial presentation with a necrotizing ulcerative gingivitis, the lesion extended to a necrotizing ulcerative stomatitis involving the surrounding periodontium and palatal mucosa. With only partial compliance to local debridement, chlorhexidine oral rinses, and systemic metronidazole therapy, alveolar bone loss resulted in tooth mobility necessitating extraction of 2 involved teeth. This case illustrates the continuum of necrotizing ulcerative infections of the periodontium in the severely immunosuppressed patient. The implications of these oral manifestations of HIV infection are discussed.


J Periodontol


Patton LL,McKaig R




Has Abstract


1998-06-01 00:00:00












  • Clinical and microbiological effects of topical subgingival application of hyaluronic acid gel adjunctive to scaling and root planing in the treatment of chronic periodontitis.

    abstract:BACKGROUND:Hyaluronic acid (HA) has shown anti-inflammatory effects in gingivitis therapy. The potential benefits of local subgingival application of HA adjunctive to scaling and root planing (SRP) were evaluated in this study. METHODS:Twenty patients with chronic periodontitis were included in this split-mouth study....

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章


    authors: Xu Y,Höfling K,Fimmers R,Frentzen M,Jervøe-Storm PM

    更新日期:2004-08-01 00:00:00

  • Radiographic and digital imaging in periodontal practice.

    abstract::This review defines terms such as accuracy, validity, and reliability, which are used to describe the quality of methods for taking x-rays and for analyzing digital images. Values for these parameters are described for techniques of taking standardized x-rays such as ear-rod fixation and fixation by use of teeth with ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审


    authors: Hausmann E

    更新日期:2000-03-01 00:00:00

  • Longitudinal observation of cementum regeneration through multiple fluorescent labeling.

    abstract::The assessment of new attachment after periodontal treatment has been the focus of continuous research. An approach to longitudinally examine the deposition of cementum was devised by using fluorescence microscopy (FL), contact microradiography (CMR), and toluidine blue staining (TBS) after the injection of three labe...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Ogura N,Mera T,Sato F,Ishikawa I

    更新日期:1991-04-01 00:00:00

  • Inter-implant bone height changes in anterior maxillary immediate and non-immediate adjacent dental implants.

    abstract:BACKGROUND:The purpose of this study was to evaluate inter-implant bone crest height changes between immediate and non-immediate dental implants placed in the anterior maxillary region. METHODS:A retrospective study was conducted on consecutively treated patients requiring at least two adjacent implants in the anterio...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Kupershmidt I,Levin L,Schwartz-Arad D

    更新日期:2007-06-01 00:00:00

  • Cervical enamel projections and associated pouch-like opening in mandibular furcations.

    abstract:BACKGROUND:Cervical enamel projections (CEPs) have been listed among the tooth-associated risk factors that could lead to isolated furcation defects around molar teeth. This is more likely when Grade III CEPs are present. However, the histologic aspects of the CEP interface with regard to the presence or absence of cem...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Blanchard SB,Derderian GM,Averitt TR,John V,Newell DH

    更新日期:2012-02-01 00:00:00

  • Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA-related kinase 7(Nek7) expression.

    abstract:BACKGROUND:Metformin, a classical treatment for diabetes mellitus, has shown sound anti-inflammatory effects. Emerging studies have focused on the mechanism underlying inflammation-related diabetic complications, such as diabetic periodontitis. Herein, we investigated the anti-inflammatory effects of metformin on the N...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Zhou X,Zhang P,Wang Q,Ji N,Xia S,Ding Y,Wang Q

    更新日期:2019-02-19 00:00:00

  • Focal dermal hypoplasia. Current concepts and differential diagnosis.

    abstract::Focal dermal hypoplasia syndrome (FDH) is a congenital disorder of mesodermal derivation with some ectodermal participation. The disorder, first described in 1962, is characterized by tenacious defects consisting of thinning of the skin; herniations of adipose tissue; abnormal skin pigmentation and other skeletal, den...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Greer RO Jr,Reissner MW

    更新日期:1989-06-01 00:00:00

  • Periodontal status and serum antibody responses to oral microorganisms in Sjögren's syndrome.

    abstract::Sjögren's syndrome is an autoimmune disease characterized by keratoconjunctivitis sicca and xerostomia. Rapid bacterial plaque accumulation occurs in Sjögren's syndrome patients due to decreases in salivary flow rate. The purpose of this study was to evaluate the periodontal status of patients with Sjögren's syndrome ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Celenligil H,Eratalay K,Kansu E,Ebersole JL

    更新日期:1998-05-01 00:00:00

  • Introduction of a mixture of β-tricalcium phosphate into a complex of bone marrow mesenchymal stem cells and type I collagen can augment the volume of alveolar bone without impairing cementum regeneration.

    abstract:BACKGROUND:The purpose of this study is to evaluate whether β-tricalcium phosphate (β-TCP) could be a promising modality to help augment alveolar bone in periodontal tissue regeneration by bone marrow mesenchymal stem cells (BMMSCs). METHODS:Expanded BMMSCs and atelocollagen (Col) were mixed together (MSC/Col). A comb...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Nagahara T,Yoshimatsu S,Shiba H,Kawaguchi H,Takeda K,Iwata T,Mizuno N,Fujita T,Kurihara H

    更新日期:2015-03-01 00:00:00

  • Guided tissue regeneration with dentin biomodification.

    abstract::This study was undertaken to provide histologic observations on the effectiveness of citric acid and tetracycline HCl root surface demineralization when used in conjunction with guided tissue regeneration (GTR) procedures. Eight beagle dogs with naturally-occurring periodontitis were initially treated with scaling and...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Dyer BL,Caffesse RG,Nasjleti CE,Morrison EC

    更新日期:1993-11-01 00:00:00

  • Root coverage using the coronally positioned flap with or without a subepithelial connective tissue graft.

    abstract:BACKGROUND:Various surgical techniques have been proposed for treating gingival recession. This randomized clinical trial compared the coronally positioned flap (CPF) alone or in conjunction with a subepithelial connective tissue graft (SCTG) in the treatment of gingival recession. METHODS:Eleven non-smoking subjects ...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: da Silva RC,Joly JC,de Lima AF,Tatakis DN

    更新日期:2004-03-01 00:00:00

  • Specific antibodies and their potential role in periodontal diseases.

    abstract::Periodontal diseases are thought to result from inflammatory responses to bacterial challenges in the gingival crevicular area. Antibodies are a major host-protective mechanism in many bacterial infections. Consequently, the antibody responses to suspected periodontal pathogenic bacteria have been extensively measured...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审


    authors: McArthur WP,Clark WB

    更新日期:1993-08-01 00:00:00

  • Use of furcal bone sounding to improve accuracy of furcation diagnosis.

    abstract::Accurate diagnosis of periodontal destruction in the furcation region of multi-rooted teeth is a critical component of treatment planning, with different therapeutic approaches chosen based upon clinical determination of the severity of involvement. The current study assessed both vertical and horizontal depths of 274...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Mealey BL,Neubauer MF,Butzin CA,Waldrop TC

    更新日期:1994-07-01 00:00:00

  • Gingival crevicular fluid matrix metalloproteinase-8 levels following adjunctive use of meloxicam and initial phase of periodontal therapy.

    abstract:BACKGROUND:The purpose of the present study was to assess the effects of adjunctive meloxicam on the matrix metalloproteinase-8 (MMP-8) levels of gingival crevicular fluid (GCF) in chronic periodontitis patients following the initial phase of periodontal therapy. METHODS:Twelve chronic periodontitis patients received ...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Buduneli N,Vardar S,Atilla G,Sorsa T,Luoto H,Baylas H

    更新日期:2002-01-01 00:00:00

  • Bacterial invasion in experimental gingivitis in man.

    abstract::Gingival biopsies of the mesial papilla area of the first molar were obtained from each patient at 0-, 14- and 21-day intervals during plaque formation. The biopsies were fixed, serially sectioned, and Gram-stained. The incidence and distribution of the bacteria-like structures were studied by microscopy. In all the s...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Saglie FR,Pertuiset JH,Rezende MT,Sabet MS,Raoufi D,Carranza FA Jr

    更新日期:1987-12-01 00:00:00

  • Clinical and laboratory studies on human sclera allografts.

    abstract::In the first section of this two-part report human peripheral blood leukocytes were tested for reactivity to extracts of sclera. Absence of scleral antigenicity is suggested by the results which showed that the leukocytes reacted similarly in sclera stimulated cultures and in the controls. The second part of the repor...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Iacono VJ,Gomes BC,Sciubba JJ,Davis RK,Klingsberg J,Baer PN

    更新日期:1980-04-01 00:00:00

  • Histologic evaluation of the effects of intrasulcular toothbrushing on human sulcular epithelium.

    abstract::Nineteen young adult Caucasian males had an average Gingival Index Score of 0.47. Each was asked to demonstrate his present method of toothbrushing: thirteen used the scrub method, and six combined the scrub and roll methods. Control gingival tissue specimens were taken from the mandibular left first bicuspid or first...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Fry HR,App GR

    更新日期:1978-04-01 00:00:00

  • Correlation between volatile sulphur compounds and certain oral health measurements in the general population.

    abstract::Oral malodor was measured using a portable sulphide monitor in 2,672 individuals aged 18 to 64 years. In addition, dental (DMFT) and periodontal conditions (CPITN and attachment loss), dental plaque, and tongue coating status were assessed. Before clinical examination, subjects were interviewed about their oral health...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Miyazaki H,Sakao S,Katoh Y,Takehara T

    更新日期:1995-08-01 00:00:00

  • Altered cell motility and attachment with titanium surface modifications.

    abstract:BACKGROUND:Titanium implants are widely used in dentistry to replace lost teeth. Various surface modifications have been used to improve implant retention and osseointegration. This study is designed to compare the ability of three titanium surfaces to promote cell attachment and cell motility of cells relevant to peri...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Palaiologou A,Stoute D,Fan Y,Lallier TE

    更新日期:2012-01-01 00:00:00

  • The effect of diabetes on tooth loss caused by periodontal disease: A nationwide population-based cohort study in South Korea.

    abstract:BACKGROUND:Our purpose was to compare the risk of tooth loss caused by periodontal disease between diabetic and nondiabetic individuals and to estimate the relative risk of tooth loss according to the severity and control of diabetes. METHODS:We selected 10,215 individuals who were diagnosed as diabetics in the Korean...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Yoo JJ,Kim DW,Kim MY,Kim YT,Yoon JH

    更新日期:2019-06-01 00:00:00

  • Reexamining the association between smoking and periodontitis in the dunedin study with an enhanced analytical approach.

    abstract:BACKGROUND:Smoking is a major risk factor for periodontal disease. Conventional oral epidemiology approaches have found strong, consistent associations between chronic smoking and periodontal attachment loss (AL) through ages 26, 32, and 38 years, but those statistical methods disregarded the data's hierarchical struct...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Zeng J,Williams SM,Fletcher DJ,Cameron CM,Broadbent JM,Shearer DM,Thomson WM

    更新日期:2014-10-01 00:00:00

  • Association of plasma 25-hydroxyvitamin d concentrations and pathogenic oral bacteria in postmenopausal females.

    abstract:BACKGROUND:Previous findings of an association between 25-hydroxyvitamin D [25(OH)D] concentrations and periodontal disease may be partially explained by the antimicrobial properties of vitamin D. To the best of the authors' knowledge, no study has investigated the association between 25(OH)D and pathogenic oral bacter...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Sahli MW,Wactawski-Wende J,Ram PK,LaMonte MJ,Hovey KM,Genco RJ,Andrews CA,Millen AE

    更新日期:2014-07-01 00:00:00

  • BDNF/HMW-HA complex as an adjunct to nonsurgical periodontal treatment of ligature-induced periodontitis in dogs.

    abstract:BACKGROUND:Recently, brain-derived neurotrophic factor (BDNF)/high molecular weight hyaluronic acid (HMW-HA) complex with flap surgery has been shown to promote periodontal tissue regeneration. The objective of this study was to evaluate the effects of local subgingival application of BDNF/HMW-HA complex adjunctive to ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Sasaki S,Takeda K,Takewaki M,Ouhara K,Kajiya M,Mizuno N,Fujita T,Kurihara H

    更新日期:2019-01-01 00:00:00

  • Comparisons of various anthropometric indexes with localized Stage II/III periodontitis in young adults: The CHIEF oral health study.

    abstract:BACKGROUND:A J-shaped relationship of body mass index (BMI) with severe periodontitis has been reported. However, it is unknown for other anthropometric indexes in young adults. METHODS:A cross-sectional study examined the relationships in 325 military men and women, aged 20 to 45 years in Taiwan. Anthropometric index...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Tsai KZ,Huang RY,Cheng WC,Su FY,Lin YP,Chang CY,Lin GM

    更新日期:2020-11-03 00:00:00

  • Early healing of hydroxyapatite-coated implants in grafted bone of zoledronic acid-treated osteoporotic rabbits.

    abstract:BACKGROUND:Resorption of grafted bone and delayed osseointegration of implants are main problems associated with alveolar bone augmentation in dental implantology, especially for patients with osteoporosis. The aim of this study is to investigate the early healing response of implants to systemic treatment of zoledroni...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Li JP,Li P,Hu J,Dong W,Liao NN,Qi MC,Li JY

    更新日期:2014-02-01 00:00:00

  • Peri-implant soft tissue phenotype modification and its impact on peri-implant health: A systematic review and network meta-analysis.

    abstract:BACKGROUND:The peri-implant soft tissue phenotype (PSP) encompasses the keratinized mucosa width (KMW), mucosal thickness (MT), and supracrestal tissue height (STH). Numerous approaches to augment soft tissue volume around endosseous dental implants have been investigated. To what extent PSP modification is beneficial ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审


    authors: Tavelli L,Barootchi S,Avila-Ortiz G,Urban IA,Giannobile WV,Wang HL

    更新日期:2021-01-01 00:00:00

  • The inductive properties of human dentin and cementum.

    abstract::Studies of the inductive properties of human dentin and cementum have yielded differing results. Comparisons are difficult to draw because of variations in time, donor tissue, host immunologic status, implant site, decalcifying agents and degree of decalcification. Analysis of the many experiments intimates that the a...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Morris ML

    更新日期:1985-11-01 00:00:00

  • Bone demineralization with citric acid enhances adhesion and spreading of preosteoblasts.

    abstract:BACKGROUND:Previous studies have demonstrated that bone demineralization can improve consolidation in bone grafts. The biologic mechanisms underlying this phenomenon remain unclear. METHODS:Twelve adult male guinea pigs were used in this experiment. Forty-five bone samples removed from the calvaria of nine animals wer...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: de Rezende ML,Coesta PT,de Oliveira RC,Salmeron S,Sant'Ana AC,Damante CA,Greghi SL,Consolaro A

    更新日期:2015-01-01 00:00:00

  • Alveolar bone regeneration after removal of inflammatory and traumatic factors.

    abstract::In this investigation periodontal destruction was produced by a combination of inflammatory and traumatic factors. After the inflammation was resolved and the trama stopped, a significant amount of alveolar bone regeneration took place. The implications of these findings for the management of advanced periodontal dise...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Kantor M,Polson AM,Zander HA

    更新日期:1976-12-01 00:00:00

  • Validation of antibiotic efficacy on in vitro subgingival biofilms.

    abstract:BACKGROUND:Systemic antibiotics are often used as adjunctive treatment modalities for periodontal diseases. Testing of antimicrobial efficacy can be relevant only if the bacteria are in the form of biofilms rather than the planktonic state, and at concentrations of physiologic relevance, i.e., reachable in the periodon...

    journal_title:Journal of periodontology

    pub_type: 杂志文章


    authors: Belibasakis GN,Thurnheer T

    更新日期:2014-02-01 00:00:00