Abstract:
BACKGROUND:Morning breath odor is an often-encountered complaint. This double-blind, crossover, randomized study aimed to examine the bad breath-inhibiting effect of 3 commercially available mouthrinses on morning halitosis during an experimental period of 12 days without mechanical plaque control. METHODS:Twelve medical students with a healthy periodontium refrained from all means of mechanical plaque control during 3 experimental periods of 12 days (with intervening washout periods of at least 3 weeks). A professional oral cleaning preceded each period. During each experimental period, as the only oral hygiene measure allowed, the students rinsed twice a day with one of the following formulations in a randomized order: CHX-Alc (a 0.2% chlorhexidine [CHX] solution); CHX-NaF (CHX 0.12% plus sodium fluoride 0.05%); or CHX-CPC-Zn (CHX 0.05% plus cetylpyridinium chloride 0.05% plus zinc lactate 0.14%). After 12 days, morning breath was scored via volatile sulfur compound (VSC) level measurements of the mouth air and organoleptic ratings of the mouth air, the expired air, and a scraping of the tongue coating. At the 12-day visit, a questionnaire (subjective ratings) was completed and samples taken from both the tongue coating and the saliva for anaerobic and aerobic culturing and vitality staining. The de novo supragingival plaque formation was also recorded. All parameters were correlated with the baseline registrations. RESULTS:Although oral hygiene during the 3 experimental periods was limited to oral rinses, bad breath parameters systematically improved, with the exception of a slight increase in VSC levels while using CHX-Alc, a finding which was associated with the direct influence of the CHX on the sulfide monitor. The oral microbial load after the use of CHX-NaF remained unchanged, while for the CHX-Alc and CHX-CPC-Zn, significant reductions in both aerobic and anaerobic colony forming units (CFU)/ml were noticed in comparison with baseline data for both tongue coating and saliva samples. The composition of microflora, on the other hand, did not reveal significant changes. The supragingival plaque formation was inhibited, in descending order, by CHX-Alc, CHX-CPC-Zn, and CHX-NaF. The subjective scores for the rinses indicated a higher appreciation for CHX-CPC-Alc and CHX-NaF because of a better taste and fewer side effects. CONCLUSIONS:The results of this study demonstrate that morning halitosis can be successfully reduced via daily use of mouthrinses. CHX-Alc and CHX-CPC-Zn mouthrinses result in a significant reduction of the microbial load of tongue and saliva.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
van Steenberghe D,Avontroodt P,Peeters W,Pauwels M,Coucke W,Lijnen A,Quirynen Mdoi
10.1902/jop.2000.72.9.1183subject
Has Abstractpub_date
2001-09-01 00:00:00pages
1183-91issue
9eissn
0022-3492issn
1943-3670journal_volume
72pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:Pigmentations of the oral cavity are commonly noted in clinical practice and may have physiologic, non-physiologic, or pathologic etiologies. The most common non-physiologic localized pigmentation is the amalgam tattoo; another, less common, non-physiologic pigmentation is the graphite tattoo. Graphite tatto...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.9.1572
更新日期:2005-09-01 00:00:00
abstract::This report is an example of tumor metastasis to the temporomandibular joint and its effect on pain, restriction of jaw movement, and the subsequent inability of the patient to function normally. Neoplasm is not the usual etiology of myofascial pain dysfunctionsyndrome and the muscle sparm component of this patient's ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1975.46.5.309
更新日期:1975-05-01 00:00:00
abstract:BACKGROUND:The purpose of this prospective study was to compare the changes in periodontal somatosensory function and microcirculation in patients with periodontitis following initial treatment with scaling and root planing (SRP) with or without adjuvant laser therapy. METHODS:Twenty-four patients suffering from perio...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1002/JPER.19-0562
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to compare the clinical outcome of intrabony periodontal defects following treatment with a novel nanocrystalline hydroxyapatite (NHA) paste to open flap debridement. METHODS:Twenty-eight subjects, each displaying one intrabony defect with probing depth (PD) > or =6 mm and radiogra...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2008.070378
更新日期:2008-03-01 00:00:00
abstract::The purpose of the present study was to use a novel intracrevicular lavage technique to evaluate short-term effects of phase I therapy on crevicular cell populations. Nineteen patients with untreated advanced adult periodontitis were selected for phase I therapy. One side of the dentition was treated with ultrasonic c...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1995.66.3.235
更新日期:1995-03-01 00:00:00
abstract::Oral polymorphonuclear leukocytes (pmn) were obtained from 10 adult donors in good oral health using a method employing repeated mouth rinse collection. Interleukin-1β (IL-1β) mRNA was detected in freshly obtained cells by blot hybridization of total cellular RNA with a biotin labeled cDNA probe. Supernates from oral ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.9.761
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the adjunctive effect of the local application of a hyaluronan gel to scaling and root planing in the treatment of chronic periodontitis. METHODS:Twelve patients with chronic periodontitis were recruited to participate in a study with a split-mouth design and pro...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2009.090128
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been found to promote the osteoblastic differentiation of human periodontal ligament cells. Its effect depends on the delivery system used. In this study we examined the effect of rhBMP-2 on the proliferation and osteoblastic differentiation of hum...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.7.982
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Some studies have reported an association between gestational diabetes mellitus (GDM) and periodontitis. The aim of the present study is to analyze this potential association and the influence of risk variables associated with GDM. METHODS:This case-control study includes 360 women, 90 with GDM and 270 cont...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.120350
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Pentraxins are classic mediators of inflammation and markers of acute-phase reactions. Pentraxin-3 (PTX3) is the first-identified long pentraxin and is believed to be a true independent indicator of disease activity. Although a classic pentraxin, C-reactive protein, and its association with various systemic ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100526
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Caries is recognized as the prevalent proximal dental disease in adolescents, while proximal bone loss is minimal to non-existent in this population. Adolescents demonstrating an inverse disease pattern, i.e., minimal caries and active periodontitis, could provide powerful clues with regard to both diseases....
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.5.710
更新日期:2000-05-01 00:00:00
abstract::Cyclosporine A (CSA) is a widely used immunosuppressant for transplant patients and is also used for the treatment of a wide variety of systemic diseases with immunologic components. A prominent side effect of CSA administration is gingival overgrowth (hyperplasia). It has been postulated that CSA alters fibroblast ac...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.3.271
更新日期:1996-03-01 00:00:00
abstract::This longitudinal study of randomly selected Norwegian students and academicians has shown that 50% of the 17-year olds have lost no periodontal support, and the other 50% exhibited slight localized loss of attachment primarily on buccal surfaces of first molars and first bicuspids of both jaws. At 21 all students sho...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.12.607
更新日期:1978-12-01 00:00:00
abstract::This study was conducted to determine the possible influence of diabetes on the pathogenesis of periodontal disease. A total of 148 patients, 120 females and 28 males, were surveyed. Their ages ranged between 9 and 50 years, with an average age of 30. The experimental group consisted of 83 diabetics and there was a co...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.9.445
更新日期:1978-09-01 00:00:00
abstract::The purposes of this study were to determine if: 1) an association exists between cigarette smoking and signs of periodontal disease after controlling for the confounding variables of age, sex, plaque, and calculus; 2) the prevalence of 5 bacteria commonly associated with periodontal disease differs between smokers an...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.12.1225
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:Periodontal disease is one of the major oral problems encountered in patients with diabetes mellitus (DM). Vascular changes, neutrophil dysfunction, altered collagen synthesis, and genetic predisposition observed in DM may contribute to periodontitis; and the vascular alterations observed in such patients ma...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2004.75.1.91
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Epidermolysis bullosa acquisita (EBA) is an uncommon, acquired, chronic subepidermal bullous disease. This report describes a case of EBA with gingival involvement. A 43-year-old woman with EBA was referred to our clinic for periodontal therapy because of gingival tenderness and bleeding. She has been on cyc...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.4.550
更新日期:2001-04-01 00:00:00
abstract::Forty free gingival grafts were performed on 5 adult Rhesus monkeys as follows: 10 grafts were placed on recipient sites with periosteum; 10 grafts on periosteum and perforated cortical plate; 10 grafts on bared bone; and 10 grafts on perforated bared bone. All free autografts (7 X 5 X 1 mm) were taken from the palata...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.1.15
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:The role played by the internal basal lamina (IBL) and hemidesmosomes between an implant and the peri-implant epithelium (PIE) in the adherence of the epithelium to the implant is controversial. This study used rat maxilla implantation models to clarify the ultrastructure of the PIE-implant interface. METHO...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.6.961
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Obesity is considered a risk factor for periodontitis. However, its influence on periodontal therapy has not been clearly determined. The aim of this case-control study is to evaluate the association between adiposity measurements, non-surgical periodontal treatment outcomes, and influencing factors in patie...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2015.140734
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Several recent studies have indicated that total antioxidant capacity (TAOC) of plasma seems to be compromised in chronic periodontitis (ChP). The aim of this study is to investigate plasma TAOC in patients with ChP and to assess the effects of vitamin C as an adjunct to non-surgical periodontal treatment. ...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2010.100173
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:The aim of the present review is to systematically evaluate the effects of autogenous platelet concentrates on clinical outcomes of the surgical treatment of periodontal diseases. METHODS:MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched using a combination of specific se...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1902/jop.2010.100605
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Metabolic syndrome is becoming a common disorder worldwide. Studies have shown a relationship between metabolic syndrome and periodontal disease, although information on the relationship is limited. METHODS:We analyzed 1,070 Japanese people aged 40, 50, 60, and 70 years who participated in health and period...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2009.090218
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Autoinducer (AI)-2 has an important role in biofilm formation in the oral environment. Mature biofilms formed as a result of the cell-to-cell communication make it difficult to overcome periodontitis with the use of antibiotics. Previous in vitro studies suggest that quorum-sensing inhibitors (QSIs) interfer...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160070
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:This study was conducted to assess the clinical, immunological, and patient-centered outcomes of microcurrent electrotherapy on palatal wound healing. METHODS:This was a parallel, double-masked randomized clinical trial, in which 53 patients with ridge preservation indications were selected and randomly ass...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.20-0122
更新日期:2020-08-12 00:00:00
abstract:BACKGROUND:Reports have demonstrated that nutrient supplements, in particular vitamin-B complex (Vit-B), can positively influence wound healing processes. However, limited information is available on the effects of Vit-B on periodontal wound healing. METHODS:A total of 30 patients (13 males, 17 females) presenting wit...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2005.76.7.1084
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Resorption of grafted bone and delayed osseointegration of implants are main problems associated with alveolar bone augmentation in dental implantology, especially for patients with osteoporosis. The aim of this study is to investigate the early healing response of implants to systemic treatment of zoledroni...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.130046
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Guided bone regeneration (GBR) has been widely utilized for the promotion of bone augmentation in bone loss areas. However, little information has been available regarding chronological changes in newly formed bone and alterations in the nature of newly formed bone after removal of a barrier membrane. The pr...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.3.341
更新日期:2000-03-01 00:00:00
abstract::T-cell subsets extracted from chronically inflamed periodontal tissues were identified using monoclonal antibodies, and their functional activity was analysed using the autologous mixed lymphocyte reaction (AMLR). Tissue was obtained from a total of 33 adult periodontitis (AP) patients and 6 normal/marginal gingivitis...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.8.569
更新日期:1987-08-01 00:00:00
abstract:BACKGROUND:Recent studies showed the clinical benefits of a one stage full-mouth disinfection, when compared to the worldwide standard treatment strategy of consecutive root planings per quadrant without proper disinfection of the remaining intraoral niches. The purpose of this study was to investigate the microbiologi...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1999.70.6.646
更新日期:1999-06-01 00:00:00