Abstract:
:The purpose of this study was to assess the clinical and microbiological effects of a newly developed root conditioning gel system containing tetracycline or a mixture of tetracycline and citric acid on non-surgical periodontal therapy. Sixty-four (64) single-rooted teeth with a probing depth of 4 to 6 mm were randomly subjected to one of the following four treatments; 1) root planing alone (RP group); 2) tetracycline-containing gel alone (TCG group); 3) root planing plus tetracycline-containing gel (RP + TCG group); or 4) root planing plus a mixture of tetracycline and citric acid-containing gel (RP + TC-CAG group). Probing depth, attachment level, and tooth mobility were measured and the presence of dental plaque and gingival inflammation was recorded at baseline and after 2, 4, 8, and 12 weeks. Subgingival plaque samples from each site were collected at the same visits and examined with phase contrast microscopy for proportions of motile rods and spirochetes. Plaque index, gingival sulcus bleeding index (SBI), probing depth, and attachment level decreased significantly in all groups compared to the baseline values (P < 0.05). A significant decrease in probing pocket depth was noted after 12 weeks in RP + TC-CAG group compared to the other groups (P < 0.05). Significantly more gain in attachment was detected in the RP + TC-CAG group compared to the TCG group (P < 0.05). Tooth mobility scores also decreased later in the study. A significant decrease in the proportion of motile rods was found primarily in the RP + TC-CAG group.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Jeong SN,Han SB,Lee SW,Magnusson Idoi
10.1902/jop.1994.65.9.840subject
Has Abstractpub_date
1994-09-01 00:00:00pages
840-7issue
9eissn
0022-3492issn
1943-3670journal_volume
65pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:There are no specific bacterial profiles or diagnostic tests capable of identifying refractory periodontitis patients before a treatment regimen is initiated. Therefore, in this high-risk cohort of patients who do not respond appropriately, host factors that might be partly under genetic control may play a c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050254
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Gingival recession (GR) defects can be treated by various methods, including acellular dermal matrix (ADM) or coronally advanced flaps (CAFs). The aim of this histomorphometric experiment is to compare the efficacy of ADM and CAF for treating GR defects in dogs. METHODS:In eight beagle dogs, a critical-size...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.120380
更新日期:2013-08-01 00:00:00
abstract::A retrospective study was conducted of 620 patients in a periodontal practice over the years 1960 to 1982. Various periodontal therapies were assessed by using careful office protocols, meticulous record-keeping and well-defined outcome criteria. Four treatment outcome categories were used: two representing satisfacto...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.5.253
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:The purpose of this single-masked, randomized, controlled clinical trial was to evaluate the effects of boric acid irrigation as an adjunct to scaling and root planing (SRP) on clinical and microbiologic parameters and compare this method with chlorhexidine irrigation and SRP alone in patients with chronic p...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2012.120467
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:A wide selection of Interdental Oral Hygiene (IOH) aids is available to consumers. Recommendations for selection are, however, limited by the lack of direct comparisons in available studies. We aimed to assess the comparative efficacy of IOH aids using Bayesian Network Meta-Analysis (BNMA). METHODS:Two inde...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/JPER.17-0368
更新日期:2018-05-01 00:00:00
abstract::Paroxysmal nocturnal hemoglobinuria (PNH) is an uncommon blood stem cell disorder. The acquired defect is in the cell membrane of the precursor of the affected clone, which renders erythrocytes, platelets and granulocytes unusually sensitive to the hemolytic effects of complement. It is characterized by chronic hemoly...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.2.115
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:Autologous bone grafts are usually well consolidated after 4 to 5 months but can be incompletely interlocked with the native bone. This study investigated the effect of acid demineralization of the graft-bed interface on graft consolidation. METHODS:Onlay bone grafts were performed on the calvaria of 36 gui...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.130298
更新日期:2014-05-01 00:00:00
abstract::Periodontal regeneration requires formation of periodontal tissues lost due to periodontal disease. To better understand the formation of new periodontal tissues during periodontal repair and regeneration, immunohistochemical expression of extracellular matrix components of normal as well as healing periodontal tissue...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.7.579
更新日期:1995-07-01 00:00:00
abstract::A study of the predominant subgingival microflora was carried out in 24 periodontitis patients, 18 to 60 years of age, in Santo Domingo, Dominican Republic. Paper point sampling, transport in VMGA III, and conventional microbiological techniques were utilized. Direct microscopic examination revealed that cocci and non...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.9.543
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the effect of strict supragingival plaque control on the subgingival microbiota in smokers and never-smokers. Research into the impact of supragingival plaque control on the number of subgingival bacteria has resulted in contradictory findings. Real-time polymeras...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2008.070558
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:The rehabilitation of the oral cavity with dental implants has become a predictable treatment modality. However, there have been only a few direct comparisons evaluating the submerged and nonsubmerged placement techniques. The purpose of this study was to characterize radiographic peri-implant bone changes f...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.3.248
更新日期:1999-03-01 00:00:00
abstract::This short report offers solutions for three common clinical problems. Based on their experience, the authors suggest using a "spoon" type partial denture for the temporary replacement of maxillary anterior teeth. The denture is unique in that it has no clasps and does not contact the marginal gingiva. Also, conventio...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.6.341
更新日期:1984-06-01 00:00:00
abstract:BACKGROUND:Peri-implantitis is an inflammatory response to bacterial biofilm resulting in bone loss and can ultimately lead to implant failure. Because of the lack of predictable treatments available, a thorough understanding of peri-implantitis's pathogenesis is essential. The objective of this study is to evaluate an...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.17-0541
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:We aimed to analyze clinical, microbiologic, and serologic effects of chlorhexidine (CHX) chips used as a subgingival controlled-release delivery device before and immediately after scaling and root planing (SRP). METHODS:Twenty-four patients presenting with ≥12 teeth with probing depth (PD) ≥5 mm and bleed...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2011.100287
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Collinin is a secondary plant metabolite belonging to the class of geranyloxycoumarins. We explored the potential beneficial impact of collinin on periodontal health by investigating its effect on Porphyromonas gingivalis (P. gingivalis), lipopolysaccharide (LPS)-induced inflammatory response of macrophages,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.120118
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:The aim of this clinical trial was to compare the outcome of non-surgical treatment of interproximal and non-interproximal Class II furcation involvements. METHODS:Thirty-eight patients presenting at least one Class II furcation involvement that bled on probing with a probing depth (PD) > or = 5 mm were rec...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2007.060312
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Caries is recognized as the prevalent proximal dental disease in adolescents, while proximal bone loss is minimal to non-existent in this population. Adolescents demonstrating an inverse disease pattern, i.e., minimal caries and active periodontitis, could provide powerful clues with regard to both diseases....
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.5.710
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Bacterial constituents, such as Gram-negative derived lipopolysaccharide (LPS), can initiate inflammatory bone loss through induction of host-derived inflammatory cytokines. The aim of this study was to establish a model of aggressive inflammatory alveolar bone loss in rats using LPS derived from the periodo...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060321
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Surgical crown lengthening has been proposed as a means of facilitating restorative procedures and preventing periodontal injuries in teeth with structurally inadequate clinical crowns or exposing tooth structure in the presence of deep, subgingival pathologies which may hamper the access for proper restorat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.7.841
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:The habit of chewing areca quid (AQ) has been implicated in oral pathogenesis, including periodontal disease. Little is understood about the roles of AQ in the cytokine secretion by immune cells. The study examined the effects of areca nut, the major ingredient of AQ, on the production of interleukin (IL)-6 ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.060039
更新日期:2006-12-01 00:00:00
abstract::Serial histological sections of gingiva obtained from each of six advanced adult periodontitis, two localized juvenile periodontitis and two periodontally healthy patients were used for specific identification of bacteria within the oral epithelium and adjacent connective tissue. Healthy gingival biopsies served as co...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1986.57.8.492
更新日期:1986-08-01 00:00:00
abstract:BACKGROUND:The purpose of the present study was to assess the effects of adjunctive meloxicam on the matrix metalloproteinase-8 (MMP-8) levels of gingival crevicular fluid (GCF) in chronic periodontitis patients following the initial phase of periodontal therapy. METHODS:Twelve chronic periodontitis patients received ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2002.73.1.103
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The clinical use of an enamel matrix derivative (EMD) has been shown to promote formation of new cementum, periodontal ligament (PDL), and bone and to significantly enhance the clinical outcomes after regenerative periodontal surgery. It is currently unknown to what extent the bleeding during periodontal sur...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.110404
更新日期:2012-07-01 00:00:00
abstract::Twelve gingival samples removed from 6 human volunteers were sectioned in small pieces, parts of which served as uncultured pieces. The remaining pieces were organ cultured for 5 hours in control, compound 48/80, and antihuman IgE media. Uncultured tissues, cultured tissues, and cultured spent media were analyzed spec...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1975.46.3.171
更新日期:1975-03-01 00:00:00
abstract:BACKGROUND:Purified recombinant human platelet-derived growth factor BB (rhPDGF-BB) is a potent wound healing growth factor and stimulator of the proliferation and recruitment of both periodontal ligament (PDL) and bone cells. The hypothesis tested in this study was that application of rhPDGF-BB incorporated in bone al...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2003.74.9.1282
更新日期:2003-09-01 00:00:00
abstract::The American Academy of Periodontology has developed the following parameter on the treatment of "refractory" periodontitis. Patients should be informed of the disease process, therapeutic alternatives, potential complications, expected results, and their responsibility in treatment. Consequences of no treatment shoul...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.5-S.859
更新日期:2000-05-01 00:00:00
abstract::Wounds were prepared in the oral cavity of 15 rabbits and five dogs, and an enzyme-solubilized calfskin collagen was placed over the surgery sites on one side. The contralateral sides acted as controls. Results indicated that the membrane was biologically acceptable to the oral mucosa of rabbits and dogs. Th collagen ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1979.50.5.250
更新日期:1979-05-01 00:00:00
abstract:BACKGROUND:This review addresses the ability of a commercially available genetic susceptibility test to determine the risk of developing severe chronic periodontitis. The test is used to detect the simultaneous occurrence of allele 2 at the IL-1A+4845 and IL-1B+3954 loci. If both of these polymorphisms are present, pat...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析
doi:10.1902/jop.2002.73.2.231
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:The purpose of this multicenter randomly controlled clinical trial was to compare two acellular dermal matrix (ADM) materials produced by different processing techniques, freeze-dried (FDADM) and solvent-dehydrated (SDADM) ADM, in their ability to correct Miller Class I and II recession defects. METHODS:Eig...
journal_title:Journal of periodontology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1902/jop.2014.140198
更新日期:2014-12-01 00:00:00
abstract::Standard wounds of simple incision and partial excision of the dentogingival junction were made in miniature swine. The healing from the 1st to the 14th day were described clinically and histologically, and the standardization of the wounds permitted quantitative and statistical analysis. In wounds that are closely ad...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1980.51.6.318
更新日期:1980-06-01 00:00:00