Clinical and laboratory characterization of early onset periodontitis.

Abstract:

:Clinical and laboratory data were compared in 72 patients with localized periodontitis (LP) and 103 patients with generalized periodontitis (GP). Significantly more LP than GP cases had decreased neutrophil chemotaxis (CTX), and were seropositive for Actinobacillus actinomycetemcomitans (Aa). Significantly, more GP cases were seropositive for Bacteroides gingivalis (Bg). All clinical indices were similar on affected teeth in LP and GP, but the attachment loss was greater on clinically unaffected teeth in GP when compared with LP. LP cases with CTX defects had a significantly lower mean age, were more often seropositive for Aa antibodies, and were more often female than LP patients with normal CTX. Significantly more GP cases with CTX defects were seropositive for Aa antibody. GP patients with normal CTX had a higher plaque index on both affected and unaffected teeth than did GP patients with a CTX defect. Our data suggest that chemotaxis and/or specific bacteria may be contributory, but not always necessary, factors in these disorders. The overlap in clinical and laboratory profiles of LP and GP continues to cloud the distinction of these early onset forms of periodontitis.

journal_name

J Periodontol

authors

Astemborski JA,Boughman JA,Myrick PO,Goodman SB,Wooten RK,Agarwal S,Vincent JW,Suzuki JB

doi

10.1902/jop.1989.60.10.557

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

557-63

issue

10

eissn

0022-3492

issn

1943-3670

journal_volume

60

pub_type

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