Irritant contact stomatitis: a review of the condition.

Abstract:

:Several different types of interactions are possible between a chemical, a mixture of chemicals, and associated extrinsic factors (i.e., mechanical irritation) in the oral mucosa. These interactions can be broadly classified as irritative or allergenic in nature. In each case, the pathology usually includes mucosal inflammation. The information compiled and reviewed in this article suggests that, given the broad definition of surface lesions/mucosal abnormalities, there may be a continuum of irritation that can be termed "irritant contact stomatitis." This may be due to the fact that the mouth is lined with highly vascular mucosa that turns over rapidly compared to the skin, and may or may not be covered by keratin. Some regions in the mouth are uniquely sensitive to irritants because they can penetrate through the tissue easily. Key factors involved in the potential development of irritation are: inherent irritation potential of the agent, amount of exposure (concentration, duration, and frequency), ability to penetrate the tissue, and inherent reactivity of the subject as well as other extrinsic factors. Irritation leading to oral mucosal alterations is a common occurrence caused by a wide variety of exposures and insults to the oral cavity. Various irritants such as foods, chemicals, friction, thermal/mechanical injury, metals, spices, and oral care products have been documented to cause irritant reactions in susceptible individuals, particularly if used under exaggerated exposure conditions. It is important to note that most irritation in the oral cavity tends to reverse quickly when the causative agent is removed. Oral irritation is a commonly occurring phenomenon. Thus, it is important that the clinician be aware of the clinical manifestations and etiology of the condition.

journal_name

J Periodontol

authors

Davis CC,Squier CA,Lilly GE

doi

10.1902/jop.1998.69.6.620

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

620-31

issue

6

eissn

0022-3492

issn

1943-3670

journal_volume

69

pub_type

杂志文章,评审
  • Can toothpaste or a toothbrush with antibacterial tufts prevent toothbrush contamination?

    abstract:BACKGROUND:Periopathogens and cariogenic species survive more than 48 hours on toothbrushes even under dry storage. This study examined a decontamination of toothbrushes by means of the bactericidal effect of different toothpastes or a special coating of the tufts. METHODS:Eight untreated periodontitis patients were p...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2003.74.3.312

    authors: Quirynen M,De Soete M,Pauwels M,Gizani S,Van Meerbeek B,van Steenberghe D

    更新日期:2003-03-01 00:00:00

  • Periodontal parameters around implants anchoring orthodontic appliances: a series of case reports.

    abstract:BACKGROUND:Implants replacing missing teeth provide advantages over clinical orthodontic treatment as compensation for reaction forces is no longer necessary and the lack of teeth is immediately resolved. METHODS:A total of 38 two-stage implants were inserted (16 in maxilla, 22 in mandible) in 10 partially edentulous ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2004.75.1.176

    authors: Molly L,Willems G,van Steenberghe D,Quirynen M

    更新日期:2004-01-01 00:00:00

  • Effects of cigarette smoke condensate and nicotine on human gingival fibroblast-mediated collagen degradation.

    abstract:BACKGROUND:Members of the matrix metalloproteinase (MMP) family have been shown to be involved in periodontal disease. Risk factors for periodontal disease include tobacco smoking. Cigarette smoke condensate (CSC) is comprised of thousands of chemicals. Nicotine is one of the active components in tobacco. This study co...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.100540

    authors: Zhang W,Fang M,Song F,Windsor LJ

    更新日期:2011-07-01 00:00:00

  • Effect of systemically administered naproxen sodium on clinical parameters and myeloperoxidase and elastase-like activity levels in gingival crevicular fluid.

    abstract:BACKGROUND:The present study was conducted to determine the possible effect of naproxen sodium on clinical status and the enzymatic profile of gingival crevicular fluid (GCF) when given as adjunct to periodontal treatment. METHODS:A total of 34 subjects with chronic periodontitis were selected and divided into two gro...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2007.060412

    authors: Aras H,Cağlayan F,Güncü GN,Berberoğlu A,Kilinç K

    更新日期:2007-05-01 00:00:00

  • Levels of pentraxin-3 in gingival crevicular fluid and plasma in periodontal health and disease.

    abstract:BACKGROUND:Pentraxins are classic mediators of inflammation and markers of acute-phase reactions. Pentraxin-3 (PTX3) is the first-identified long pentraxin and is believed to be a true independent indicator of disease activity. Although a classic pentraxin, C-reactive protein, and its association with various systemic ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.100526

    authors: Pradeep AR,Kathariya R,Raghavendra NM,Sharma A

    更新日期:2011-05-01 00:00:00

  • Serum lipoprotein-associated phospholipase A₂ and C-reactive protein levels in association with periodontal disease and hyperlipidemia.

    abstract:BACKGROUND:The aim of this study is to evaluate the levels of serum lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) and high-sensitivity C-reactive protein (hsCRP) in association with periodontal disease and hyperlipidemia. METHODS:A total of 123 subjects with hyperlipidemia and 68 systemically healthy controls ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.100417

    authors: Fentoğlu O,Köroğlu BK,Kara Y,Doğan B,Yılmaz G,Sütçü R,Ay ZY,Tonguç MÖ,Orhan H,Tamer MN,Kırzıoğlu FY

    更新日期:2011-03-01 00:00:00

  • Histologic evaluation of autogenous connective tissue and acellular dermal matrix grafts in humans.

    abstract:BACKGROUND:The clinical success of root coverage with autogenous connective tissue (CT) or acellular dermal matrix (ADM) has been well documented. However, limited histological results of CT grafts have been reported, and a case report of a human block section has been published documenting an ADM graft. The purpose of...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.2005.76.2.178

    authors: Cummings LC,Kaldahl WB,Allen EP

    更新日期:2005-02-01 00:00:00

  • Individual composition of human leukocyte antigens and periodontopathogens in the background of periodontitis.

    abstract:BACKGROUND:Human leukocyte antigens (HLAs) are a basic precondition to induce the immune response to pathogens. Therefore, this study evaluates associations among periodontitis, five key periodontopathic bacteria, and HLAs to test their impact together with additional risk factors in multivariate analyses. METHODS:Eig...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.110545

    authors: Reichert S,Altermann W,Stein JM,Schaller HG,Machulla HK,Schulz S

    更新日期:2013-01-01 00:00:00

  • Periodontal regeneration of human intrabony defects. IV. Determinants of healing response.

    abstract::The purpose of this study was to identify factors which might affect the healing response in intrabony defects treated with guided tissue regeneration. Selected sites presented with deep periodontal lesions with 1, 2, and 3 wall combination intrabony component of 6.1 +/- 2.5 mm. The significance of patient, tooth, and...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1993.64.10.934

    authors: Tonetti MS,Pini-Prato G,Cortellini P

    更新日期:1993-10-01 00:00:00

  • Long-term results of guided tissue regeneration therapy in the treatment of class II furcation defects: a randomized clinical trial.

    abstract:BACKGROUND:The purpose of this study was to evaluate the results after guided tissue regeneration (GTR) using a bioabsorbable membrane in Class II furcation defects in mandibular molars over a 24-month period. METHODS:Nine patients with 2 comparable Class II furcation defects were included. The defects in each patient...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.2003.74.1.3

    authors: Cury PR,Sallum EA,Nociti FH Jr,Sallum AW,Jeffcoatt MK

    更新日期:2003-01-01 00:00:00

  • Periodontal assessment by right- and left-handed examiners: is there a difference?

    abstract:BACKGROUND:Multiple factors that influence the precision of periodontal probing measurements have been identified. These factors can be categorized as being dependent upon host-related, probe-related, or examiner-related variables. However, the potential influence of examiner handedness (right or left) on the measureme...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050185

    authors: Khan SM,Blanchard SB,Dowsett SA,Eckert GJ,Kowolik MJ

    更新日期:2006-07-01 00:00:00

  • Analysis of consecutively placed loaded root-form and plate-form implants in adult Macaca mulatta monkeys.

    abstract::The present paper describes 36 consecutively treated non-human primates (Macaca mulatta) as part of a balanced block design study to examine osseointegration in root- and plate-form implants prepared by atraumatic preparation of bone. Clinical measurements around selected teeth and digital radiology were utilized to m...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.12.1322

    authors: Fritz ME,Braswell LD,Koth D,Jeffcoat M,Reddy M,Brogan D,Cotsonis G,Winter M,Lemons JE

    更新日期:1996-12-01 00:00:00

  • The role of CD4+ cells in vivo on the induction of the immune response to Porphyromonas gingivalis in mice.

    abstract:BACKGROUND:It has previously been suggested that CD4+ T cells play a pivotal role in regulating the immune response to periodontal pathogens. The aim of the present study therefore was to determine delayed type hypersensitivity (DTH), spleen cell proliferation, serum and splenic anti-Porphyromonas gingivalis antibody l...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2002.73.10.1133

    authors: Sosroseno W,Bird PS,Gemmell E,Seymour GJ

    更新日期:2002-10-01 00:00:00

  • Effects of repeated hand instrumentation on the marginal portion of a cast gold crown.

    abstract::A study was conducted to evaluate the effects of repeated hand instrumentation on the marginal portion of a cast gold crown. Seven extracted periodontally diseased premolars were used. The finishing line of the preparation was placed on the root surface and then the crown was cast and cemented in the usual manner. One...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1998.69.1.41

    authors: Yagi H,Ito K,Eda M,Murai S

    更新日期:1998-01-01 00:00:00

  • Forty-eight-month periodontal attachment loss incidence in a population-based cohort study: role of baseline status, incident tooth loss, and specific behavioral factors.

    abstract:BACKGROUND:The objectives of this study were to: 1) test hypotheses that behavioral factors, baseline clinical status, and incident tooth loss are significantly associated with attachment loss incidence (ALI) and 2) quantify the effect of incident tooth loss on conclusions made about ALI. METHODS:The Florida Dental Ca...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2005.76.7.1161

    authors: Gilbert GH,Shelton BJ,Fisher MA

    更新日期:2005-07-01 00:00:00

  • Bone demineralization with citric acid enhances adhesion and spreading of preosteoblasts.

    abstract:BACKGROUND:Previous studies have demonstrated that bone demineralization can improve consolidation in bone grafts. The biologic mechanisms underlying this phenomenon remain unclear. METHODS:Twelve adult male guinea pigs were used in this experiment. Forty-five bone samples removed from the calvaria of nine animals wer...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2014.130657

    authors: de Rezende ML,Coesta PT,de Oliveira RC,Salmeron S,Sant'Ana AC,Damante CA,Greghi SL,Consolaro A

    更新日期:2015-01-01 00:00:00

  • Fusobacterium nucleatum T18 aggregates human mononuclear cells and inhibits their PHA-stimulated proliferation.

    abstract::In previous studies Fusobacterium nucleatum has been shown to induce either stimulatory or inhibitory effects on human mononuclear cells. We examined the interaction of human mononuclear cells with human and cynomolgus monkey strains of F. nucleatum. Peripheral blood mononuclear cells (PBMCs) isolated from normal dono...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1997.68.1.39

    authors: Kinder Haake S,Lindemann RA

    更新日期:1997-01-01 00:00:00

  • Longitudinal observation of cementum regeneration through multiple fluorescent labeling.

    abstract::The assessment of new attachment after periodontal treatment has been the focus of continuous research. An approach to longitudinally examine the deposition of cementum was devised by using fluorescence microscopy (FL), contact microradiography (CMR), and toluidine blue staining (TBS) after the injection of three labe...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1991.62.4.284

    authors: Ogura N,Mera T,Sato F,Ishikawa I

    更新日期:1991-04-01 00:00:00

  • In vivo assay of crevicular leukocyte migration. Its development and potential applications.

    abstract::Defects in neutrophil or polymorphonuclear leukocyte (PMNL) chemotaxis have been observed in a number of clinical conditions, including Down's syndrome and insulin-dependent diabetes mellitus (IDDM), which tend to be associated with severe forms of periodontal disease. In addition, impaired PMNL chemotaxis is frequent...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.1985.56.11s.56

    authors: Iacono VJ,Singh S,Golub LM,Ramamurthy NS,Kaslick R

    更新日期:1985-11-01 00:00:00

  • Traumatic lesions of the gingiva: a case series.

    abstract:BACKGROUND:The most recent classification of periodontal diseases includes a new section on traumatic gingival lesions. Traumatic lesions of the gingiva are thought to be highly prevalent, yet the periodontal literature contains few references on the topic. The purpose of this article is to present a broad spectrum of ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2004.75.5.762

    authors: Rawal SY,Claman LJ,Kalmar JR,Tatakis DN

    更新日期:2004-05-01 00:00:00

  • Cyclooxygenase-2-Dependent Prostaglandin (PG) E2 Downregulates Matrix Metalloproteinase-3 Production via EP2 /EP4 Subtypes of PGE2 Receptors in Human Periodontal Ligament Cells Stimulated With Interleukin-1α.

    abstract:BACKGROUND:Prostaglandin E2 (PGE2 ), which exerts its actions via EP receptors (EP1 , EP2 , EP3 , and EP4 ), is a bioactive metabolite produced by cyclooxygenase (COX)-1 and/or COX-2 from arachidonic acid. In the present study, we investigated whether COX-2-derived PGE2 regulated matrix metalloproteinase (MMP)-3 produc...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2005.76.6.929

    authors: Yan M,Noguchi K,Ruwanpura SMPM,Ishikawa I

    更新日期:2005-06-01 00:00:00

  • The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model.

    abstract:BACKGROUND:Low-calorie diets are commonplace for reducing body weight. However, no information is available on the effects of a reduced-calorie diet on periodontal inflammation and disease. The purpose of this study was to evaluate the clinical effects of a long-term calorie-restriction (CR) diet on periodontitis in an...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.070629

    authors: Branch-Mays GL,Dawson DR,Gunsolley JC,Reynolds MA,Ebersole JL,Novak KF,Mattison JA,Ingram DK,Novak MJ

    更新日期:2008-07-01 00:00:00

  • Periodontal wound healing with and without platelet-rich plasma: histologic observations and assessment of flap tensile strength.

    abstract:BACKGROUND:Platelet-rich plasma (PRP) has been promoted as a surgical adjunct to enhance hard and soft tissue wound healing. Although anecdotally reported to be of value, the results of controlled studies examining the added effects of PRP on surgical procedures have been mixed. The purpose of this study was to test th...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.080626

    authors: Powell CA,Bannister SR,Mackey SA,Maller SC,McDonnell HT,Deas DE

    更新日期:2009-06-01 00:00:00

  • Interferon-γ, interleukins-6 and -4, and factor XIII-A as indirect markers of the classical and alternative macrophage activation pathways in chronic periodontitis.

    abstract:BACKGROUND:Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which interferon (IFN)-γ and interleukin-6 (IL)-6 of the classic pathway and IL-4 of the alternative pathway ha...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.130078

    authors: Navarrete M,García J,Dutzan N,Henríquez L,Puente J,Carvajal P,Hernandez M,Gamonal J

    更新日期:2014-05-01 00:00:00

  • Axonal transport of fluorescent carbocyanine dyes allows mapping of peripheral nerve territories in gingiva.

    abstract::Sensory innervation of gingival tissue can cause neurogenic inflammation that depends on the extent of the branching area of the peripheral nerve fibers. We designed the present study to determine whether single trigeminal axons branch to both the buccal and palatal gingiva of maxillary molars of adult rats. Accumulat...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1995.66.9.817

    authors: Sugaya A,Chudler EH,Byers MR

    更新日期:1995-09-01 00:00:00

  • Association between periodontal pockets and elevated cholesterol and low density lipoprotein cholesterol levels.

    abstract:BACKGROUND:Periodontitis is associated with increased prevalence of cardiovascular morbidity and mortality; however, the nature of this association is unclear. There is a rationale that indicates that the presence of periodontal pockets which can harbor pathogenic microorganisms and evoke a host response could elicit a...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2002.73.5.494

    authors: Katz J,Flugelman MY,Goldberg A,Heft M

    更新日期:2002-05-01 00:00:00

  • Alveolar bone resorption induced by CD4+CD45RB high-density T-cell transfer in immunocompromised mice.

    abstract:BACKGROUND:The aims of this study are to determine whether the antigen-inexperienced (naive, CD45RB high-density) T-cell (CD4(+)CD45RB(High) T-cell) transfer model is associated with alveolar bone resorption, to elucidate the local osteogenic/adipogenic potential of alveolar bone marrow stromal cells (ABCs) from T-cell...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2014.140077

    authors: Park JC,Kim BK,Jung IH,Choi E,Kim CS

    更新日期:2014-09-01 00:00:00

  • Periodontal manifestations of the heritable Mac-1, LFA-1, deficiency syndrome. Clinical, histopathologic and molecular characteristics.

    abstract::The clinical, histopathologic and functional consequences of the genetic deficiency of leukocyte Mac-1, LFA-1 and p150,95 were assessed among three affected patients, heterozygotes and unaffected individuals among two generations of a single kindred. Longitudinal assessments of this family afforded the unique opportun...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1987.58.6.400

    authors: Waldrop TC,Anderson DC,Hallmon WW,Schmalstieg FC,Jacobs RL

    更新日期:1987-06-01 00:00:00

  • The relationship between clinical periodontal status and insulin-dependent diabetes mellitus. Results after 5 years.

    abstract::The clinical periodontal status of 44 insulin-dependent diabetic children and adolescents and 20 healthy control subjects was compared for a period of approximately 5 years. Fasting blood glucose, fructosamine, and glycosylated hemoglobin (HbA1) values were determined at baseline and 5 years later. The differences in ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1997.68.2.136

    authors: Firatli E

    更新日期:1997-02-01 00:00:00

  • Periodontal disease in HIV seropositive patients and its relation to lymphocyte subsets.

    abstract::This study was performed to determine the type of periodontal pathology found in a group of HIV+ patients and its relation to serum levels of CD4. The sample consisted of 101 individuals: intravenous drug users (84%), homosexuals (7%), and heterosexuals (10%). Each patient was examined clinically and radiographically....

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.1.33

    authors: Martínez-Canut P,Guarinos J,Bagán JV

    更新日期:1996-01-01 00:00:00